The document outlines the tablet manufacturing process, including various types of tablets such as compressed, sugar-coated, and enteric-coated tablets, as well as the steps involved in their production. It details processes like blending, granulation, and compression, specifying tooling types and their lifespan. Additionally, it discusses evaluation tests for tablets and the purposes and methods of coating.

1. TABLET MANUFACTURING
PROCESS

2. TABLETS
• Tablets may be defined as the solid
unit dosage form of medicament or
medicaments with suitable excipients
and prepared either by moulding or by
compression. It comprises a mixture of
active substances and excipients.

3. 1. Compressed Tablets (CT)
2. Sugar Coated Tablets (SCT)
3. Film-Coated Tablets (FCT)
4. Enteric-Coated Tablets (ECT)
5. Multiple Compressed tablets
(MCT)
5.1 Layered Tablets,
5.2 Press-Coated Tablets
6. Controlled Release tablets.
TYPES OF TABLETS
7. Tablets for Solution /
Dispersible Tablets
8. Effervescent tablets
9. Compressed Suppositories or
inserts
10. Buccal and Sublingual Tablets.
11. Vaginal tablets...
12. Lozenges.
13. Implants.

4. TABLET PROCESS FLOW
BLENDING
DISPENSING

5. GRANULATION
• Small powder particles are gathered
together into layers, and permanent
aggregates to render them into free-
flowing states.

6. GRANULATION METHODS

7. COMPRESSION
TYPES OF
TOOLING
‘B’ Tooling ‘D’ Tooling
‘BB’ Tooling ‘DB’ Tooling

8. Type of product Punch set life
Circular 20 million / set
Other than circular 16 million / set
Multilayer (circular) 16 million / set
Multilayer (other than circular) 8 million / set
Effervescent tablet 8 million / set
• PUNCH SET LIFE SPAN
• MATERIAL OF CONSTRUCTION
PUNCHES: AISI O1 (OHNS)
DIES: AISI D3 (HCHC)
HIGHLY ABRASIVE PRODUCT: AISI D2 (HCHC)

9. STEPS INVOLVED IN COMPRESSION

10. • PARTS OF A ROTARY PRESS
1. Hopper
2. Feeder system
3. Punches
4. Die system
5. Turret
6. Cam Tracks
7. Fill Cam and Dose Cam
8. Compression Rollers
9. Ejection Cam
10.Discharge Chute

12. Evaluation tests for Tablets
1. Appearance, Height, Length, and Width.
2. Weight variation test
3. Hardness test
4. Friability test
5. Dissolution test
6. Disintegration test

13. COATING
WHY coating is required
1. To mask taste, odour and appearance.
2. Protect drug from gastric environment.
3. Provide physical and chemical protection.
4. To avoid incompatibilities between drugs.
5. Improve pharmaceutical elegance.

14. TYPES OF COATING
SUGAR COATING
FILM COATING
ENTERIC COATING

15. Conventional Pan Coaters Modern Coating Pan

16. FLUIDIZED BED WRUSTER COATING PROCESS