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ORAL MANIFESTATIONS OF SYSTEMIC MEDICAL DISORDER.pptx
- 1. ORAL MANIFESTATIONS OF SYSTEMIC MEDICAL DISORDER MODERATER/GUIDE: DR. KAVITA BENDWAL MAM ASSOCIATE PROFESSOR RDGMC UJJAIN PRESENTER: DR. AGRASHI AGRAWAL (JR1)
- 2. ORAL CAVITY
- 3. CLASSIFICATION •SYSTEMIC INFECTIOUS DISEASE •CONNECTIVE TISSUE DISEASE •GASTROINTESTINAL DISEASE •HEMATOLOGICAL DISEASE •ENDOCRINE DISEASE •NUTRITIONAL DEFICIENCY •DRUG REACTION/ RADIOTHERAPY •DERMATOLOGICAL DISEASE
- 5. VIRAL DISEASES 1. Primary herpatic gingivostomatitis 2. Recurrent herpes labialis 3. Recurrent intraoral herpes simplex 4. Chickenpox 5. Herpes zoster 6. Infectious mononucleosis 7. Herpengina 8. Hand foot and mouth disease 9. Primary HIV infection
- 6. HERPES ZOSTER Usual location: Cheek, tongue, gingiva, or palate
- 7. PRIMARY HERPATIC GINGIVOSTOMATITIS Usual location: lip and oral mucosa
- 8. RECURRENT HERPES LABIALIS Usual location: Mucocutaneous junction of lip, perioral skin
- 9. RECURRENT INTRAORAL HERPES SIMPLEX Usual location: Palate and gingiva
- 10. CHICKENPOX Usual location: Gingiva and oral mucosa
- 11. INFECTIOUS MONONUCLEOSIS Usual location: Oral mucosa
- 12. HIV INFECTION Usual location: Gingiva, palate, and pharynx
- 15. BACTERIAL DISEASES 1. Acute necrotizing ulcerative gingivitis (“trench mouth”) 2. Prenatal (congenital) syphilis 3. Primary syphilis (chancre) 4. Secondary syphilis 5. Tertiary syphilis 6. Gonorrhea 7. Tuberculosis
- 16. ACUTE NECROTIZING ULCERATIVE GINGIVITIS (“TRENCH MOUTH”) Usual Location: Gingiva
- 17. SYPHILIS
- 18. Primary syphilis (chancre) Lesion appearing where organism enters body; may occur on lips, tongue, or tonsillar area Secondary syphilis Oral mucosa frequently involved with mucous patches, which occur primarily on palate and also at commissures of mouth Tertiary syphilis Palate and tongue
- 19. GONORRHEA Usual Location: Lesions may occur in mouth at site of inoculation or secondarily by hematogenous spread from a primary focus
- 20. TUBERCULOSIS Usual Location: Tongue, tonsillar area, soft palate
- 21. FUNGAL DISEASES 1. Cervicofacial actinomycosis 2. Histoplasmosis 3. Candidiasis
- 23. CERVICOFACIAL ACTINOMYCOSIS Usual Location: Swellings in region of face, neck, and floor of mouth Infection may be associated with extraction, jaw fracture, or eruption of molar tooth; in acute form, resembles acute pyogenic abscess, but contains yellow “sulfur granules” (gram-positive mycelia and their hyphae)
- 24. HISTOPLASMOSIS
- 25. HISTOPLASMOSIS Ususal Location: Any area of the mouth, particularly tongue, gingiva, or palate Nodular, verrucous, or granulomatous lesions; ulcers are indurated and painful; usual source hematogenous or pulmonary, but may be primary
- 26. CANDIADIASIS
- 27. CANDIADIASIS Usual location: Any area in mouth Clinical feature: Pseudomembranous type (“thrush”): creamy white curdlike patches that reveal a raw, bleeding surface when scraped; found in sick infants, debilitated elderly patients receiving high-dose glucocorticoids or broad-spectrum antibiotics, and patients with AIDS Erythematous type: flat, red, sometimes sore areas in same groups of patients Course same as for pseudomembranous type Candidal leukoplakia: nonremovable white thickening of epithelium due to Candida Angular cheilitis: sore fissures at corner of mouth
- 29. CONNECTIVE TISSUE DISORDERS Systemic lupus erythematosus Discoid lupus erythematosus Sjogrens syndrome Scleroderma Sarcoidosis Wegner’s Granulomatosis Behecet’s Syndrome Amyloidosis Kawasaki Disease Cowden Disease
- 34. SCLERODERMA
- 35. AMYLOIDOSIS
- 36. SARCOIDOSIS
- 39. KAWASAKI DISEASE
- 40. COWDEN DISEASE
- 41. DERMATOLOGIC DISEASES Mucous membrane pemphigoid Stevens-Johnson syndrome Pemphigus vulgaris Lichen planus
- 43. MUCOUS MEMBRANE PEMPHIGOID Usual Location: Typically produces marked gingival erythema and ulceration; other areas of oral cavity, esophagus, and vagina may be affected
- 45. PEMPHIGUS VULGARIS Usual Location: Oral mucosa and skin; sites of mechanical trauma (soft/hard palate, frenulum, lips, buccal mucosa)
- 46. LICHEN PLANUS
- 47. LICHEN PLANUS Usual Location: Oral mucosa and skin White striae in mouth; purplish nodules on skin at sites of friction; occasionally causes oral mucosal ulcers and erosive gingivitis
- 48. HEMAOLOGICAL DISORDERS •Iron deficiency anemia •Pernicious anemia •Plummer vinson syndrome •Leukaemia
- 52. LEUKAEMIA (USUALLY MONOCYTIC) Usual Location: Gingiva
- 53. GASTROINTESTINAL DISEASES Inflammatory bowel diseases Crohn’s disease Ulcerative colitis Gastroesophageal reflux disease Celiac disease Chronic liver disease Malabsorption syndrome
- 54. CROHNS DISEASE
- 55. CELIAC DISEASE
- 60. ADDISON’S DISEASE Usual Location: Any area of mouth, but mostly buccal mucosa Blotches or spots of bluish-black to dark-brown pigmentation occurring early in disease, accompanied by diffuse pigmentation of skin; other symptoms of adrenal insufficiency
- 61. NUTRITIONAL DEFICIENCIES •Vitamin B2 deficiency •Vitamin B3 deficiency •Vitamin C deficiency •Vitamin B12 Deficiency
- 63. VITAMIN B3 (NIACIN) DEFICIENCY
- 67. VITAMIN 12 DEFICIENCY (PERNICIOUS ANEMIA)
- 68. PERNICIOUS ANEMIA Atrophic glossitis in a patient with pernicious anemia. Mucosal atrophy appears as smooth, bald areas devoid of lingual papillae on the dorsal tongue.
Editor's Notes
- Linear ulceration at the depth of the left mandibular buccal vestibule in a patient with Crohn disease. Erythematous, polypoid nodule of the superior buccal mucosa in a patient with Crohn disease.