Oral diseases, especially periodontitis has been proposed as having an etiological role in cardiovascular and cerebrovascular disease, diabetes, respiratory disease and adverse pregnancy outcome.
Oral lesions are indicators of disease progression and oral cavity can be a window to systemic disease. Hence good oral health is important to your overall well-being.
Oral lesions are indicators of disease progression and oral cavity can be a window to systemic disease. Hence good oral health is important to your overall well-being.
Oral diseases, especially periodontitis has been proposed as having an etiological role in cardiovascular and cerebrovascular disease, diabetes, respiratory disease and adverse pregnancy outcome.
Oral lesions are indicators of disease progression and oral cavity can be a window to systemic disease. Hence good oral health is important to your overall well-being.
Oral lesions are indicators of disease progression and oral cavity can be a window to systemic disease. Hence good oral health is important to your overall well-being.
Orofacial syndromes are rare but not uncommon, knowledge about these various syndromes aids in early detection, genetic counselling, symptomatic & aesthetic management. The pediatric dentist especially play a pivotal role in assessing & managing such patients for improving the quality of life in such long standing diseases.
Definition
Epidemiology
Causes and Risk Factors
Clinical Presentation
Types
Diagnosis
Treatment
Prognosis
Case Scenario
8 Roles of family physician in psoriasis
Management Options
PREMATURE AGING SYNDROMES AND THEIR CLINICAL MANIFESTATIONSDR. MOHNISH SEKAR
Aging is an inevitable consequence of human life resulting in a gradual deterioration of cell, tissue and organismal function and an increased risk to develop chronic ailments. Premature aging syndromes, also known as progeroid syndromes, recapitulate many clinical features of normal aging and offer a unique opportunity to elucidate fundamental mechanisms that contribute to human aging. Progeroid syndromes can be broadly classified into those caused by perturbations of the nuclear lamina, a meshwork of proteins located underneath the inner nuclear membrane (laminopathies); and a second group that is caused by mutations that directly impair DNA replication and repair.
COMPLICATIONS OF DIABETES BY DR BASHIR AHMED DAR ASSOCIATE PROFESSOR MEDICINE...Prof Dr Bashir Ahmed Dar
The complications of diabetes mellitus are far less common and less severe in people who have well-controlled blood sugar levels.Wider health problems accelerate the deleterious effects of diabetes. These include smoking, elevated cholesterol levels, obesity, high blood pressure, and lack of regular exercise.
3. 3
•Oral manifestation may herald the onset of
some diseases or may be late manifestations
•May be seen in oral soft tissues including
the tongue
•May occur in the jaw bones and/or the teeth
•Both soft and hard tissue manifestations may
arise in some systemic diseases
•A manifestation based approach is presented
•Not comprehensive
4. 4
Angular cheilitis
• Iron deficiency
anaemia
• Folic Acid deficiency
• Vit B12 deficiency
• Vit B2 (riboflavin)
deficiency
• Vit B6 (pyridoxine
deficiency)
• Malabsorption states
(eg: Crohn’s disease)
• AIDS
• Other immune defects
19. 19
Burning sensation in the mouth
• Iron deficiency
• Folate deficiency
• Vitamin B12 deficiency
• Vitamin B complex deficiency
• Diabetes mellitus
• Xerostomia of systemic causes
• States of anxiety and depression
• Hypothyroidism
20. 20
Numbness of orofacial areas
(including lips)
• Intracranial neoplasia
• Trotter’s syndrome
• Leukaemia
• Metastatic disease of the jaws
• Diabetes mellitus
• Sarcoidosis
• Amyloidosis
• Sickle cell disease
29. 29
Some localised gingival
swellings of systemic origin
Strawberry gingivitis
in Wegener’s
granulomatosis
Gingival swellings in
Tuberous sclerosis (mental
handicap, epilepsy and
sebaceous adenomas on
skin)
32. 32
Blood blisters in the mouth
• Any cause of purpura
• Mucous membrane pemphigoid
• Amyloidosis
• (Localized oral purpura- angina bullosa
haemorrhagica)
57. 57
Systemic diseases causing radiological
abnormalities of the jaws
• Hyperparathyroidism and Hypoparathyroidism
• Multiple myeloma
• Haemoglobinopathies
• Acromegaly
• Osteogenesis imperfecta
• Albers-Schonberg disease (marble bone dis)
• Histiocytosis X
• Fibrous dysplasia
• Paget’s disease
• Systemic sclerosis
58. 58
Oral manifestations of internal
cancer
• Metastases in jaws or rarely oral soft tissues
(Breast, Lung, Prostate, Thyroid, Kidney, Stomach)
• Effects of tumour metabolites
– Facial flushing- carcinoid syndrome
– Pigmentation (ectopic ACTH-secreting tumours)
– Amyloidosis (multiple myeloma)
– Oral erosions (glucaganoma)
contd…..
59. 59
Oral manifestations of internal
cancer (contd..)
• Changes caused by other functional disturbances
– Purpura, anaemia, infections (Leukaemia)
– Infections (lymphoma, especially Hodgkin’s dis’se)
– Bleeding (liver cancer)
• Anaemia (bleeding from gastrointestinal tumours)
• Mucocutaneous diseases
– Acanthosis nigricans (gastric Ca)
– Erythema multiforme (lymphoma, leukaemia )
– Pempigus, pemphigoid (paraneoplastic pemphigus in
lymphomas)
contd…..
60. 60
Oral manifestations of internal
cancer (contd..)
• Inherited disorders with predisposition to internal
malignancy and oral lesions
– Gardner’s syndrome
– Cowden’s syndrome
– Multiple endocrine neoplasia syndrome type III
– Neurofibromatosis
– Gorlin Goltz syndrome
– Tylosis
– Tuberous sclerosis
– Maffuci syndrome
61. 61
Conclusion
• Oral manifestations of several systemic diseases are of
considerable diagnostic value
• By recognizing them the dental clinician can contribute to
early diagnosis of the disease and thereby to the welfare of the
patient.
• It is therefore imperative for dental surgeons to be aware of
these manifestations
