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Oral fluid drug testing
- 1. Oral Fluid DrugTesting: A Simple Solution for a Complex World Guest Speaker: Ben Agee Oral Fluid Scientist, Keystone Laboratory Moderator: Kendra McCardle Business Relationship Director for Wolfe, Inc.
- 2. “Never underestimate thepower of a simple tool.” - Craig Bruce ORAL FLUID DRUG TESTING: A SIMPLE SOLUTION FOR A COMPLEX WORLD
- 3. “WOLFE WORDS” Adulterated –made impure by adding extraneous, improper, or inferior ingredients Neat Sample – a sample obtained by expectorating (spitting) rather than through a medium such as a pad or buffer Metabolite – a product of metabolic action Substituted – any sample not produced by the donor
- 4. A “neat” oralfluid sample is the best method of collection for the highest percentage of drug recovery. -SAMHSA Proposed Revisions to Mandatory Guidelines for Federal Workplace Drug Testing Programs Sample Collection is the Key Not all samples are equal (even the best drug test is only as good as the specimen) No buffers No diluents No pads
- 5. Less non-productive timefor donors and collectors Ideal for onsite collecting Totally observable No donor privacy concerns Less set-up time Dual gender observations No “shy bladder” issues
- 6. Saves time and productivity Reducesthe likelihood of possible adulteration/substitution Ideal for post-accident testing, pre-employment testing, random testing and reasonable suspicion testing Only a 5 step collection process If the donor does not have to leave the facility
- 7. Fast, easy andconvenient sample collection Premium Oral Fluid Collector
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- 9. 75,400 websites haveadvice on beating urine-based screening - Google Dilute AdulteratedSubstituted
- 10. Oral fluid drugtesting can detect current drug use. The window of detection in oral fluid drug testing is 12-24 hours. Oral Fluid is great for: For Cause Post Accident Random Tests Return to Duty Pre- Employment
- 11. Marijuana is themost commonly used illicit drug • is the primary compound and psychoactive ingredient in marijuana • (parent) is the most prevalent marijuana compound in saliva • becomes very sticky when warm and tends to cling to porous surfaces • is the most difficult drug to recover in oral fluid testing Δ9- THC
- 12. “The recovery ofΔ9-THC from devices with absorbing components is a problem. The recovery of Δ9-THC is not as good as that of other analytes due to the absorption of Δ9 THC to the plastic and the absorptive compounds of the device.” *Langel, K., C. Engblom, et al. (2008). "Drug testing in oral fluid- evaluation of sample collection devices." Journal of Analytical Toxicology 32(6): 393-401. Inadequate Recovery Δ9-THC in Collection Devices
- 13. * Sample collectionis fast and easy * No pads, no buffers and no diluents to affect sample integrity * Unaltered sample for maximum recovery * Glass is a better collection container vs. plastic for THC recovery and screening accuracy Premium Oral Fluid Collector
- 14. Equally important isa device with a sample volume indicator -SAMHSA Proposed Revisions To Mandatory Guidelines for Federal Workplace Drug Testing Programs Without an Indicator No objective way to measure sample volume Large variations are problematic to get quantitative results for drug recovery Collected sample volume can vary from 18-83%
- 15. � Accurate sample volumesare necessary to ensure accurate results � Easy to read fill line ensures sufficient sample volume � Decreases rejections for insufficient quantity Premium Oral Fluid Collector
- 16. � Δ9-THC � Cocaine �Opiates � PCP � Amphetamine � Methamphetamine � MDMA (Ecstasy)
- 17. � Oral fluidspecimens accounted for only 5% of collected samples in 2009 �We project that by 2016 approximately 20% (over 20 million) of all collected specimens will be oral fluid samples Reproduced from A Five Year Analysis of Oral Fluid Drug Testing Results from a MRO Data Source, 2003-2007; Walsh, J.M., et al., 2008 Society of Forensic Toxicology National Meeting and data collected from the field in 9/09. Data is conservative and only shows one MRO source. 2009 data point from personal communication with J.M.Walsh. 0 500000 1000000 1500000 2000000 2500000 3000000 3500000 2003 2004 2005 2006 2007 2008 2009 Oral Fluid Trends
- 18. � 75%+ ofdrug users have jobs � There are between 10 million and 12 million drug users in the workplace � It is estimated businesses lose between $129 billion and $180 billion per year due to productivity losses to drug use � Drug users are 33% less productive than their co-workers, and on average cost their employers between $7,000 and $15,000 annually U.S. Department of Labor, Occupational Safety & Health Administration website; Safety and Health Topics, Workplace Substance Abuse. Calculating Savings for Higher Positive Rates
- 19. � Easy tocollect � Difficult to adulterate �Better indicator of recent drug use
- 20. Featured Presenter Ben Agee OralFluid Scientist, Keystone Laboratory Ben is the resident Oral Fluid scientist for Keystone Laboratory in Asheville, NC. He graduated from Western Carolina University with a degree in Biology. Contact Ben directly at 1.800.230.2991 or at BennettA@WolfeInc.com
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