The article discusses Salmonellosis, an important zoonotic disease caused by Salmonella bacteria. It causes heavy losses to poultry farmers through diseases like Pullorum disease and Fowl typhoid. In humans, it can cause foodborne illnesses. Strict biosecurity measures, vaccination, rodent control, and proper hygiene during meat processing and cooking can help control Salmonella. Left untreated, it poses a risk to both animal and human health.