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Translating Data into Clinical
Change
Hants Williams, PhD, RN
Founder & Chief Innovation Officer - BioVirtua
The Black Box of Data
Part 1 - Problem
Part 2 – Solutions
and Toolkit
Part 3 – Taking action
and Executing
My Journey
Data & Blackbox
Nurses
Birds eye view of my journey thus far…
Home Education Consulting
Founder
Duke University, PhD
Nonpharmacological pain management
Development of remote MBSR protocols
UMMC, Postdoc
Pain Genetics
RNA sequencing multidimensional pain
Parsley Health
Data Scientist
Customer insights, health outcomes
pulseData
Health Informaticist
Data translation, clinical recommendations
Robincare
Intervention consultant
Mindfulness-based interventions for cancer
Data ? Outcome
Data ML/Ai Outcome
“Data Scientist Stuff”
“Statistics is the science of learning from
data...” - American Statistical Association
Data ML/Ai Outcome
Data ML/Ai ? ⇧ Outcome
Translate into
action
Data ML/Ai OutcomeNurses
Mathematical Models  Translation Improved Health
Basic Science  Translational Science  Clinical Science
Data
Problem
ML/Ai ModelModel Translation
Intervention with
Metric
Real world example:
Background: pulseData, preventable chronic diseases with machine
learning – chronic kidney disease
Problem: exploring partnership with Oscar health, how could they
integrate, provide additional value
Solution:
High Level Game Plane
1. Literature Review [pubmed, ebscho, uptodate]– find evidenced based
interventions to support the implementation of some type of
intervention (most likely nurse, PT, social worker led)
2. Human Capital - hospital/client resources (e.g., social workers, nurse
specialists) that are already in place
3. Understand output from ML/Ai specialists – what it can and can’t do
4. Pairing of human capital resources to EBP’s
Do nurses need
to become
experts in ML/Ai?
No
Do nurses need
to understand
basics of ML/Ai?
Yes
Data scientists are not trained in:
• Anatomy
• Disease/pathology
• Pharmacogenetics
• Acute Health
• Hospital Operations/Management
Data scientists’ are
mathematicians/visualization
experts that should be agnostic
to the context or scenario
Can create ML/Ai models, but not
healthcare professionals, and are
not trained to translate their
findings into improved patient
outcomes
Nurses’ are focused on improving
patient reported outcomes/metrics
through delivery of evidenced-based
care
Nurses are trained and
knowledgeable of healthcare
interventions that could be
delivered, and what may be most
effective
Famous Failures and Problems
IBM Watson – University Texas
“The partnership between IBM and one of the world’s
top cancer research institutions is falling apart. The
project is on hold, MD Anderson confirms, and has
been since late last year. MD Anderson is actively
requesting bids from other contractors who might
replace IBM in future efforts. And a scathing report
from auditors at the University of Texas says the
project cost MD Anderson more than $62 million and
yet did not meet its goals. The report, however, states:
‘Results stated herein should not be interpreted as an
opinion on the scientific basis or functional capabilities
of the system in its current state’….”
https://www.technologyreview.com/s/607965/a-reality-check-for-ibms-ai-ambitions/
Are there opportunities?
• pulseData --> They create risk scores for preventable illnesses, but
what do they do with those scores?
• Parsley Health --> They provide adjunct doctor visits and health
coaching interactions, but lack evidenced-based protocols for coaches
• Robincare  Using non-pharmacological approaches for managing
cancer in young adults, but with approaches that are not matched
with the condition (e.g., generic use of mindfulness)
Omada Care (prediabetes)
Vita Health (weight management)
Flatiron (cancer)
The best part of this ‘blackbox’ - you don’t need to
be a data scientist, you need to be a nurse with
only a basic understanding of what is under the
hood
“…provide input to the overall NIH vision and actions undertaken by
each of the 27 Institutes and Centers in support of biomedical research
as a digital enterprise. Among other duties, the office oversees the Big
Data to Knowledge (BD2K) initiative, stimulating the best developments
in the data science community.”
Patricia Flatley Brennan, RN, PhD
NIH Interim Associate Director for Data Science
National Library of Medicine Director
My Toolbox (“stack”)
How I Utilize Free & Open Source Tools
to…
1. Find opportunities (e.g., clients, projects)
2. Learning basic ‘data science’ – a.k.a how to make pretty graphs and do
statistics
3. Attract and sell my skillset
Discloser: I am receiving no monetary or other forms of compensations from
any of the services I am about to discuss
Findings Opportunities and Clients
Data Specific Tools to Solve The Problems
Interact w/data
Example
code
Visualize &
Report
Getting The Word Out – my skills
Wordpress and the Divi Theme – Getting the Word Out
Wordpress and the Divi Theme – Getting the Word Out
Where’s the value?
Alternatives to VC money-
My contact:
Personal email: hantsawilliams@gmail.com
650-218-3789
Schedule some time to chat with me @
https://calendly.com/hants

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Nurses and Data Science

  • 1. Translating Data into Clinical Change Hants Williams, PhD, RN Founder & Chief Innovation Officer - BioVirtua The Black Box of Data
  • 2. Part 1 - Problem Part 2 – Solutions and Toolkit Part 3 – Taking action and Executing
  • 3. My Journey Data & Blackbox Nurses
  • 4. Birds eye view of my journey thus far… Home Education Consulting Founder
  • 5. Duke University, PhD Nonpharmacological pain management Development of remote MBSR protocols UMMC, Postdoc Pain Genetics RNA sequencing multidimensional pain Parsley Health Data Scientist Customer insights, health outcomes pulseData Health Informaticist Data translation, clinical recommendations Robincare Intervention consultant Mindfulness-based interventions for cancer
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  • 8. Data ML/Ai Outcome “Data Scientist Stuff”
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  • 10. “Statistics is the science of learning from data...” - American Statistical Association
  • 12. Data ML/Ai ? ⇧ Outcome Translate into action
  • 14. Mathematical Models  Translation Improved Health Basic Science  Translational Science  Clinical Science
  • 16. Real world example: Background: pulseData, preventable chronic diseases with machine learning – chronic kidney disease Problem: exploring partnership with Oscar health, how could they integrate, provide additional value Solution:
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  • 19. High Level Game Plane 1. Literature Review [pubmed, ebscho, uptodate]– find evidenced based interventions to support the implementation of some type of intervention (most likely nurse, PT, social worker led) 2. Human Capital - hospital/client resources (e.g., social workers, nurse specialists) that are already in place 3. Understand output from ML/Ai specialists – what it can and can’t do 4. Pairing of human capital resources to EBP’s
  • 20. Do nurses need to become experts in ML/Ai? No Do nurses need to understand basics of ML/Ai? Yes
  • 21. Data scientists are not trained in: • Anatomy • Disease/pathology • Pharmacogenetics • Acute Health • Hospital Operations/Management
  • 22. Data scientists’ are mathematicians/visualization experts that should be agnostic to the context or scenario Can create ML/Ai models, but not healthcare professionals, and are not trained to translate their findings into improved patient outcomes Nurses’ are focused on improving patient reported outcomes/metrics through delivery of evidenced-based care Nurses are trained and knowledgeable of healthcare interventions that could be delivered, and what may be most effective
  • 23. Famous Failures and Problems IBM Watson – University Texas “The partnership between IBM and one of the world’s top cancer research institutions is falling apart. The project is on hold, MD Anderson confirms, and has been since late last year. MD Anderson is actively requesting bids from other contractors who might replace IBM in future efforts. And a scathing report from auditors at the University of Texas says the project cost MD Anderson more than $62 million and yet did not meet its goals. The report, however, states: ‘Results stated herein should not be interpreted as an opinion on the scientific basis or functional capabilities of the system in its current state’….”
  • 26. • pulseData --> They create risk scores for preventable illnesses, but what do they do with those scores? • Parsley Health --> They provide adjunct doctor visits and health coaching interactions, but lack evidenced-based protocols for coaches • Robincare  Using non-pharmacological approaches for managing cancer in young adults, but with approaches that are not matched with the condition (e.g., generic use of mindfulness) Omada Care (prediabetes) Vita Health (weight management) Flatiron (cancer)
  • 27. The best part of this ‘blackbox’ - you don’t need to be a data scientist, you need to be a nurse with only a basic understanding of what is under the hood
  • 28. “…provide input to the overall NIH vision and actions undertaken by each of the 27 Institutes and Centers in support of biomedical research as a digital enterprise. Among other duties, the office oversees the Big Data to Knowledge (BD2K) initiative, stimulating the best developments in the data science community.” Patricia Flatley Brennan, RN, PhD NIH Interim Associate Director for Data Science National Library of Medicine Director
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  • 30. My Toolbox (“stack”) How I Utilize Free & Open Source Tools to… 1. Find opportunities (e.g., clients, projects) 2. Learning basic ‘data science’ – a.k.a how to make pretty graphs and do statistics 3. Attract and sell my skillset Discloser: I am receiving no monetary or other forms of compensations from any of the services I am about to discuss
  • 32. Data Specific Tools to Solve The Problems Interact w/data Example code Visualize & Report
  • 33. Getting The Word Out – my skills
  • 34. Wordpress and the Divi Theme – Getting the Word Out
  • 35. Wordpress and the Divi Theme – Getting the Word Out
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  • 45. My contact: Personal email: hantsawilliams@gmail.com 650-218-3789 Schedule some time to chat with me @ https://calendly.com/hants

Editor's Notes

  1. Part 1: My journey The data translation problem Solving it with nurses Part 2: How you can do the same…. A few modern day tools you will not learn in school Part 3: How I applied the tools to get where I’m at now
  2. San Francisco Educartion: DUKE, SFSU, SJSU, UMB.UMMC > Received multiple individual awards from the NIH, NINR - APS / Board Member, Consulting: PulseData/Parsley Health, RobinCare, Founder: BioVirtua Public Health Nurse, CA PhD – Non-pharm pain management; Duke University Postdoc - Pain genetics, University of Maryland Medical Center Private/individual consultant Formal: Parsley Health & pulseData Informal: Robincare BioVirtua – Founder, Chief Innovation Officer; venture capital backed
  3. [bring in some of the slides, information from old PPT that you gave after going to the NIH data science boot camp] BRING IN A LIST OF ALL THE POTENTIAL COMPANIES THAT ARE TRYING TO DO THINGS WITH ML/AI Then do a quick search of which of those companies have succeeded, failed - ? I think there is a website that also talks about the failed companies, type of angellist version, maybe see if can find out Then bring up the black box – ML/Ai is cool, but what the hell is it? What does it do?
  4. Historically, this is how things have looked:
  5. But what is a data scientist? What do they do?
  6. The real problem isn’t the black box of what the data scientist does, it’s the black box of what to then do after the data scientist finishes
  7. Save this slide for later on
  8. What famous failures our there that I can cite? IBM watson? What other startups? IBM watson: After four years it had not produced a tool for use with patients that was ready to go beyond pilot tests
  9. Wordpress.com –> You need to PAY Wordpress.org  IT IS FREE Elegant themes -> have very nice themes for wordpress  check out the DIVI theme Flaticons  is where I got all the icons for this presentation, as well as my own websites
  10. Look Out for “OLD” Money, stayed focused on healthcare knowledgeable ventures that understand you can’t expect the same return 1-yr out as you would a pure tech company