1. Informatics Research Centre
Virtual Embryo
Education Framework for Embryologists
Dr. Silvester Czanner

2. Informatics Research Centre
Researchers
Patients
MDs, Students
Database
Web service
External resources
Analysis
Evaluation
Validation
Presentation
Images
(ASRM, SART)
PGD results
Live birth outcome
BIG Picture
Embryo
Grading

3. Informatics Research Centre
Biomedical Imaging and Microscopy
• segmentation
• registration
• 3D modelling
• simulations
Rafferty, Drury, Hartshorne, Czanner, Use of Concave
Corners in the Segmentation of Embryological Datasets,
Review of Bioinformatics and Biometrics, 2012

4. Informatics Research Centre
Segmentation Methods
Expert GVF GAC MACWE MGAC
A
B
Expert hand segmentation, GVF - Gradient vector field, GAC - Geodesic
active contours, MACWE - Morphological active contours without edges
and MGAC - Morphological geodesic active contours
Thanks to IVF Unit, Warwick Medical School

5. Informatics Research Centre
Feature
detection
Embryo
selection
Semi-automatic digital embryo
selection and analysis
Analysis
Good
Bad
Mölder, Czanner, Costen, Harshorne,
Automatic Detection of Embryo Location
in Medical Imaging Using Trigonometric
Rotation for Noise Reduction, ICPR, 2014

6. Informatics Research Centre
Automatic feature selection
using image variance
Mölder, Drury, Costen, Hartshorne, Czanner, Usage of
normalized image variance for feature detection in embryonic
imaging. Cytometry, Part A 87 (2), pp 119-128, 2015

7. Informatics Research Centre
Repurpose Gaming Technologies
IVF Simulation
EYE
Tracking

8. Informatics Research Centre
Serious Games
for Training and Clinical Diagnostics

9. Informatics Research Centre
Web Services. Online Database. Security.
Prototype Architecture
Password Protected
Secure Application

10. Informatics Research Centre
Thank you for your attention.
Questions?
Academics
Dr. Silvester Czanner, MMU
Dr. Nicholas Costen, MMU
Prof. Geraldine Hartshorne, University of Warwick
PhD Students
Anna Mölder, MMU
Sarah Drury, University of Warwick
MSc Students
John Gay, Eliza Konstantinidi