The document provides an overview of Node.js architecture, highlighting its server-side nature, single-threaded model, and the use of the Chrome V8 runtime. It details components such as libuv for the event loop, asynchronous I/O, and C/C++ bindings which facilitate interaction between JavaScript and lower-level libraries. Additionally, it discusses async callback mechanisms and best practices to avoid blocking code, emphasizing the importance of managing CPU-bound tasks effectively.