The document discusses how inequality in wealth and power affects health disparities and critiques the focus of public health interventions on downstream behavioral risks rather than upstream social determinants. It highlights three challenges to implementing upstream interventions, including resistance from powerful elites, a bias towards biomedical models in public health, and a lack of robust evidence for upstream interventions. The article explores strategies to overcome these obstacles through case studies of campaigns aimed at improving living conditions, such as increasing wages and preventing mortgage foreclosures.