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NEUROLEU A
i‹ s« rxLL andio-iz%o£AMLcases, if neuro-
prophylaxis is not given along with initial therapy.
• Pathnlugical lesions include infilhation by leukemia cells,
hcmc›rrhage, and demye inati .
Symptoms:
• Irtracranial hemorrhage.
• Hyper viscosity syndrome
TREATMENT
g for 6 duct•G. Asingle loveshould
Neuroprophylaxis:
IT MT*:iO-T4mg/m•thick a
not exmd i mg
• ITcYt arakinosidc omg twicea week for 6 closos
CNS involvement should be diagnosed when the CsF count
• 5fcumm with or without the presence nf blast cells.
• Cran  or craniespinal irzadtation combined with IT MTx/ cytosine

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neuroleukemianeurosurgeryneurosurgery.pptx

  • 1. NEUROLEU A i‹ s« rxLL andio-iz%o£AMLcases, if neuro- prophylaxis is not given along with initial therapy. • Pathnlugical lesions include infilhation by leukemia cells, hcmc›rrhage, and demye inati . Symptoms: • Irtracranial hemorrhage. • Hyper viscosity syndrome
  • 2.
  • 3.
  • 4. TREATMENT g for 6 duct•G. Asingle loveshould Neuroprophylaxis: IT MT*:iO-T4mg/m•thick a not exmd i mg • ITcYt arakinosidc omg twicea week for 6 closos CNS involvement should be diagnosed when the CsF count • 5fcumm with or without the presence nf blast cells. • Cran or craniespinal irzadtation combined with IT MTx/ cytosine