this ppt is the description of natrum (sodium) group from the periodic table. this focuses on the mental, physical and general characteristics of the group.
Understanding Natrum group with elaboration of Natrum Muriaticum personality from Homoeopathic Materia Medica
By Dr. Namrata Bosamia Surati B.H.M.S., M. D. (HOM.)
Homoeopathic Medicines made out of Natrum/ Sodium group and their preparation, properties and clinical indications.
Sodium is a metallic element with symbol Na ,atomic no.11 atomicweight-22.991 silvery white lustrous alkali metal of the consistency of wax oxidising rarely in air or water. The salts of sodium are extensively used in medicine.
The document discusses different ways people eat masala dosa and claims they reveal personal traits. It describes 10 cases of dosa eating styles and assigns traits to each:
1. People who open the dosa are very open about their lives.
2. People who start from both ends and save the masala for last either want exciting lives or prefer extremes with no middle ground.
3. People who start from the middle burn out early by prioritizing pleasures over dealing with hardships.
4. People who pace the masala make sure it lasts the whole dosa, seeking balance and protecting it.
5. People who don't share their dosa are protective of their private lives
This document analyzes different personality types based on how people eat masala dosa. It describes 10 cases of people who eat dosa in different ways, such as opening it up and eating it with their hands, starting from both ends and saving the masala for last, or making sure the masala lasts throughout. Each case is associated with certain personality traits, such as being open about their life, wanting balance, or being overly generous only when their own needs are met. The document suggests looking at how someone eats dosa can reveal things about their personality.
For more such files visit Amazing Files at http://spicyflavours.net
Also plz join our group and share your ppt's with our group members
http://www.slideshare.net/group/spicy-flavours
This article is about how you be happy while feeling lonely. Whenever you feel down, the only thing that comes to mind is find happiness. It is from this background that I have provided a good way of finding happiness in your lonely moments.
Phosphorus is especially suited to tall, slender, narrow – chested persons They have mostly fair skin, blonde or red hair, and delicate eyelashes. Nervousness and sensitiveness in nature is marked among them. It is also adapted to young people, who grow too rapidly and tend to stoop. Apart from above it also suits persons who have a tendency to bleed.
Aurum metallicum is a remedy for people experiencing profound melancholy and a constant desire for suicide. They are ambitious, responsible, and honest but are also highly sensitive, introverted, and easily hurt. They strive for high achievement but experience depression when they fail due to their high expectations. This suppressed depression can manifest as rage, violence, and suicidal tendencies.
Understanding Natrum group with elaboration of Natrum Muriaticum personality from Homoeopathic Materia Medica
By Dr. Namrata Bosamia Surati B.H.M.S., M. D. (HOM.)
Homoeopathic Medicines made out of Natrum/ Sodium group and their preparation, properties and clinical indications.
Sodium is a metallic element with symbol Na ,atomic no.11 atomicweight-22.991 silvery white lustrous alkali metal of the consistency of wax oxidising rarely in air or water. The salts of sodium are extensively used in medicine.
The document discusses different ways people eat masala dosa and claims they reveal personal traits. It describes 10 cases of dosa eating styles and assigns traits to each:
1. People who open the dosa are very open about their lives.
2. People who start from both ends and save the masala for last either want exciting lives or prefer extremes with no middle ground.
3. People who start from the middle burn out early by prioritizing pleasures over dealing with hardships.
4. People who pace the masala make sure it lasts the whole dosa, seeking balance and protecting it.
5. People who don't share their dosa are protective of their private lives
This document analyzes different personality types based on how people eat masala dosa. It describes 10 cases of people who eat dosa in different ways, such as opening it up and eating it with their hands, starting from both ends and saving the masala for last, or making sure the masala lasts throughout. Each case is associated with certain personality traits, such as being open about their life, wanting balance, or being overly generous only when their own needs are met. The document suggests looking at how someone eats dosa can reveal things about their personality.
For more such files visit Amazing Files at http://spicyflavours.net
Also plz join our group and share your ppt's with our group members
http://www.slideshare.net/group/spicy-flavours
This article is about how you be happy while feeling lonely. Whenever you feel down, the only thing that comes to mind is find happiness. It is from this background that I have provided a good way of finding happiness in your lonely moments.
Phosphorus is especially suited to tall, slender, narrow – chested persons They have mostly fair skin, blonde or red hair, and delicate eyelashes. Nervousness and sensitiveness in nature is marked among them. It is also adapted to young people, who grow too rapidly and tend to stoop. Apart from above it also suits persons who have a tendency to bleed.
Aurum metallicum is a remedy for people experiencing profound melancholy and a constant desire for suicide. They are ambitious, responsible, and honest but are also highly sensitive, introverted, and easily hurt. They strive for high achievement but experience depression when they fail due to their high expectations. This suppressed depression can manifest as rage, violence, and suicidal tendencies.
Magnesium carbonate is precipitated from a solution of Epsom salts by dropping in a solution of sodium or potassium carbonate. Magnesium is found in the earth's surface, chiefly as the carbonate, and is associated with potassium and calcium salts. Magnesium carbonate is a well-known remedy for difficult, aggressive children who feel a need for recognition and acceptance. Repressed feelings from a lack of care as an infant can manifest as anxiety, especially about loved ones. Dreams or lack of dreams can also express hidden emotions.
This document discusses different types of toxic personalities to avoid, including manipulative, narcissistic, negative, judgmental, dream-killing, insincere, disrespectful, and demanding people. It provides examples of how each type can negatively impact one's happiness, self-esteem, and overall well-being through manipulation, selfishness, constant criticism, lack of support, disrespect, and unrealistic expectations. The document suggests spending time with these types of toxic personalities can inadvertently influence one's own thoughts and behaviors if not avoided.
The document discusses the color code personality theory which states that there are four core motivations - yellow, blue, red, and white - that drive all people. Each color has distinct personality traits and motivations. A person has both a primary and secondary color that influence their behavior. The combinations of primary and secondary colors result in different personality types with unique strengths and weaknesses. Understanding a person's color combination provides insight into how they are motivated and how they will behave in different situations.
The document contains a portfolio by Darren Dexter P. de Chavez that includes an autobiography, values ranking, reading log, and other works. In his autobiography, he describes himself as an adventurous person who likes exploring nature and becoming independent. He hopes to have a successful career as an engineering professional in another country someday. His values ranking prioritizes family, love, and money as most important. The portfolio is dedicated to his parents, teacher, and God for their support and encouragement.
This document discusses common problems faced by young people and their parents. It identifies lack of parental affection, lack of family time together, social anxiety disorder, eating disorders like anorexia and bulimia, depression, overuse of the internet, substance abuse, and abortion as key issues. The document stresses that these problems negatively impact the relationship between teenagers and their parents as young people become more rebellious and parents fail to establish effective rules and boundaries. It concludes parents must make difficult decisions to address issues early to prevent major problems from developing in their children's lives and families.
This document discusses grief and loss in the context of addiction and recovery. It defines grief and outlines the typical stages of grief: denial, anger, bargaining, depression, and acceptance. It notes that grief from addiction loss involves mourning not just people but old ways of living and relating. The recovery process often involves grieving the loss of rituals, relationships, and roles tied to the addiction. Managing grief in recovery requires acknowledging feelings, avoiding relapse triggers, and caring for one's physical and mental health through social support, journaling, exercise and counseling.
The document discusses different types of drugs, their effects on adolescents, and the damages caused by drug addiction. It describes stimulant drugs like amphetamines and cocaine, depressants like alcohol and benzodiazepines, and hallucinogenic drugs like LSD and marijuana. It notes that drug addiction often begins in adolescence due to problems fitting in or seeking an escape. The effects of drugs vary but include feelings of relaxation, euphoria, exhaustion and hallucinations. Drug addiction damages daily life through missed work and lost relationships, prioritizing drugs over loved ones. Long-term damages include health issues like heart attacks, mental illness, and overdose death. The conclusion emphasizes the magnitude of problems that can
15 Types of People to Avoid (at all costs)Krisman S
The document outlines 9 signs that a person is toxic: 1) They talk more than they listen and are self-centered in conversations. 2) They are never wrong and get defensive when disagreed with. 3) Drama follows them everywhere due to their victim mentality. 4) They force relationships and exaggerate connections to others. 5) They judge others based only on their own experiences. 6) They often lie to benefit themselves. 7) They lack tact and courtesy, being derogatory and boastful of their "honesty." 8) They exhibit controlling behaviors to make others act how they want. 9) They love to gossip about others and rarely find positive things to say. Having a few of these traits indicates the
It’s a wonder to me why we bother to get to know these people, but we do, and it’s very difficult to cut them out of our lives once we’ve let them in. It’s easy to talk ourselves out of taking this step, but it’s necessary if we want to maintain healthy mental and emotional states. If you’re unsure, here are some ways to spot a toxic person in your life.
The document discusses family roles that can develop in families affected by addiction. It describes six common roles: 1) The Addict, who is the center of attention due to their addiction issues. 2) The Hero, who ignores problems and presents an overly positive image. 3) The Mascot, who uses inappropriate humor to draw attention away from issues. 4) The Lost Child, who is quiet and avoids any discussion of addiction issues. 5) The Scapegoat, who acts out to divert attention from the addict's need for help. 6) The Enabler, who makes excuses and avoids acknowledging addiction problems to keep everyone happy. These roles can lead family members, especially children, to develop codependent behaviors as
This document provides information about the homeopathic remedy Lycopodium, including its botanical origins, preparation process, key symptoms, and areas of the body it affects. Lycopodium is described as being indicated for deep-seated, chronic conditions and is especially useful for intellectually keen but physically weak individuals. Its symptoms include abdominal bloating, urinary issues, cough, and anxiety about public speaking. Comparisons are made between Lycopodium and other remedies like Natrum mur.
Sensitivity Strongne Personified Natram Muriaticum Personae By Dr. Darbha Aneeta.
Homeopathic Natrum Muriaticum Personae typifies their oversensitive, Strong and retentive tendencies with an inbuilt penchant to stifling their strong emotions under a Chimera. Simply can be put as, though meticulous, hardworking and dedicated yet, do not 'let go' of their past emotions of hurt, feelings of corniness, never ever forgetting insults, reprimands; 'Hoard' things, overcautious, obsessed with their security system.
For info log on to www.healthlibrary.com.
The document discusses the culture of the Albatrosians and what can be learned from it. It notes that in their culture, women have a higher position than men and are more closely connected to the earth. Only women are allowed to remove their shoes and kneel on the earth. When eating, men must wash themselves first and eat/drink first to ensure the food is safe. The Albatrosian society appreciates silence, seriousness, and is peaceful, open to foreigners and tolerant. Their ceremonies stem from tradition and are considered very normal within their culture. The document encourages understanding that one's own culture influences observations and that what is normal differs across cultures.
1. The document provides instructions for virtual classroom rules and etiquette, including keeping cameras on, muting microphones when not speaking, and using the chat box to request to speak.
2. It then discusses different types of plants, categorizing them into those without seeds like algae and ferns, and those with seeds like flowering plants and conifers.
3. The document teaches about comparing and contrasting, providing examples and signal words to identify similarities and differences between objects or entities. It emphasizes the importance of this skill for developing writing and communication abilities.
1. Drug abuse has become a serious social problem in Indonesian society, affecting people of all ages. Though not immediately apparent, drug problems have penetrated all levels of society like an iceberg.
2. Environmental factors such as easy drug access, poor family communication, authoritarian parenting, peer pressure, and an unsafe school environment can contribute to drug use.
3. Common drugs include opiates, marijuana, amphetamines, cocaine, alcohol, and benzodiazepines. Excessive use leads to negative physical and psychological effects like euphoria, anxiety, insomnia, and organ damage.
Sept 2013 edition of whispering soul newsletterBetty Cosgrave
This document discusses the psychology of happiness. It states that happiness is commonly considered the main way to evaluate how well one's life is going. While money cannot buy happiness, regular exercise, close relationships, meaningful work, and achieving goals can increase happiness. The document also provides a 10-point list of actions people can take to improve their happiness, such as not pursuing happiness directly, being reflective, and following a healthy lifestyle.
The document discusses the themes of solitude, loneliness, and finding strength within oneself. It provides quotes on how loneliness can be overcome through solitude and learning to value one's own company. Solitude allows one to gain self-awareness and compassion for others, while loneliness leads to using others as escapes from being alone. True companionship is being alone together, and one must learn to live alone even when with others.
This document provides information about cannabis/marijuana, its effects, dependency, and quitting usage. It discusses cannabis's active chemicals and how they affect the brain. Both short-term effects like relaxation and long-term risks like increased anxiety and depression are described. Symptoms of cannabis dependency and strategies for quitting like reducing usage gradually or stopping cold turkey are presented over multiple sections.
Admissions Essay Editing - Fast And Af. Online assignment writing service.Mellisa Hedeen
Meredith Monk's piece Early Morning Melody exhibits many minimalist techniques. The song features isolated vocals that repeat a simple melody over four iterations. Monk strips the song down to just her voice, which she uses to sing the same melodic phrase. This repetition of a single melodic idea is a hallmark of minimalist music.
Though the melody repeats, the song does not feel redundant. Each repetition allows the listener to interpret the piece differently based on the lyrics and their own imagination. The lyrics conjure images of waking up early in the morning and going about a routine
Breast cancer: Post menopausal endocrine therapyDr. Sumit KUMAR
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
Magnesium carbonate is precipitated from a solution of Epsom salts by dropping in a solution of sodium or potassium carbonate. Magnesium is found in the earth's surface, chiefly as the carbonate, and is associated with potassium and calcium salts. Magnesium carbonate is a well-known remedy for difficult, aggressive children who feel a need for recognition and acceptance. Repressed feelings from a lack of care as an infant can manifest as anxiety, especially about loved ones. Dreams or lack of dreams can also express hidden emotions.
This document discusses different types of toxic personalities to avoid, including manipulative, narcissistic, negative, judgmental, dream-killing, insincere, disrespectful, and demanding people. It provides examples of how each type can negatively impact one's happiness, self-esteem, and overall well-being through manipulation, selfishness, constant criticism, lack of support, disrespect, and unrealistic expectations. The document suggests spending time with these types of toxic personalities can inadvertently influence one's own thoughts and behaviors if not avoided.
The document discusses the color code personality theory which states that there are four core motivations - yellow, blue, red, and white - that drive all people. Each color has distinct personality traits and motivations. A person has both a primary and secondary color that influence their behavior. The combinations of primary and secondary colors result in different personality types with unique strengths and weaknesses. Understanding a person's color combination provides insight into how they are motivated and how they will behave in different situations.
The document contains a portfolio by Darren Dexter P. de Chavez that includes an autobiography, values ranking, reading log, and other works. In his autobiography, he describes himself as an adventurous person who likes exploring nature and becoming independent. He hopes to have a successful career as an engineering professional in another country someday. His values ranking prioritizes family, love, and money as most important. The portfolio is dedicated to his parents, teacher, and God for their support and encouragement.
This document discusses common problems faced by young people and their parents. It identifies lack of parental affection, lack of family time together, social anxiety disorder, eating disorders like anorexia and bulimia, depression, overuse of the internet, substance abuse, and abortion as key issues. The document stresses that these problems negatively impact the relationship between teenagers and their parents as young people become more rebellious and parents fail to establish effective rules and boundaries. It concludes parents must make difficult decisions to address issues early to prevent major problems from developing in their children's lives and families.
This document discusses grief and loss in the context of addiction and recovery. It defines grief and outlines the typical stages of grief: denial, anger, bargaining, depression, and acceptance. It notes that grief from addiction loss involves mourning not just people but old ways of living and relating. The recovery process often involves grieving the loss of rituals, relationships, and roles tied to the addiction. Managing grief in recovery requires acknowledging feelings, avoiding relapse triggers, and caring for one's physical and mental health through social support, journaling, exercise and counseling.
The document discusses different types of drugs, their effects on adolescents, and the damages caused by drug addiction. It describes stimulant drugs like amphetamines and cocaine, depressants like alcohol and benzodiazepines, and hallucinogenic drugs like LSD and marijuana. It notes that drug addiction often begins in adolescence due to problems fitting in or seeking an escape. The effects of drugs vary but include feelings of relaxation, euphoria, exhaustion and hallucinations. Drug addiction damages daily life through missed work and lost relationships, prioritizing drugs over loved ones. Long-term damages include health issues like heart attacks, mental illness, and overdose death. The conclusion emphasizes the magnitude of problems that can
15 Types of People to Avoid (at all costs)Krisman S
The document outlines 9 signs that a person is toxic: 1) They talk more than they listen and are self-centered in conversations. 2) They are never wrong and get defensive when disagreed with. 3) Drama follows them everywhere due to their victim mentality. 4) They force relationships and exaggerate connections to others. 5) They judge others based only on their own experiences. 6) They often lie to benefit themselves. 7) They lack tact and courtesy, being derogatory and boastful of their "honesty." 8) They exhibit controlling behaviors to make others act how they want. 9) They love to gossip about others and rarely find positive things to say. Having a few of these traits indicates the
It’s a wonder to me why we bother to get to know these people, but we do, and it’s very difficult to cut them out of our lives once we’ve let them in. It’s easy to talk ourselves out of taking this step, but it’s necessary if we want to maintain healthy mental and emotional states. If you’re unsure, here are some ways to spot a toxic person in your life.
The document discusses family roles that can develop in families affected by addiction. It describes six common roles: 1) The Addict, who is the center of attention due to their addiction issues. 2) The Hero, who ignores problems and presents an overly positive image. 3) The Mascot, who uses inappropriate humor to draw attention away from issues. 4) The Lost Child, who is quiet and avoids any discussion of addiction issues. 5) The Scapegoat, who acts out to divert attention from the addict's need for help. 6) The Enabler, who makes excuses and avoids acknowledging addiction problems to keep everyone happy. These roles can lead family members, especially children, to develop codependent behaviors as
This document provides information about the homeopathic remedy Lycopodium, including its botanical origins, preparation process, key symptoms, and areas of the body it affects. Lycopodium is described as being indicated for deep-seated, chronic conditions and is especially useful for intellectually keen but physically weak individuals. Its symptoms include abdominal bloating, urinary issues, cough, and anxiety about public speaking. Comparisons are made between Lycopodium and other remedies like Natrum mur.
Sensitivity Strongne Personified Natram Muriaticum Personae By Dr. Darbha Aneeta.
Homeopathic Natrum Muriaticum Personae typifies their oversensitive, Strong and retentive tendencies with an inbuilt penchant to stifling their strong emotions under a Chimera. Simply can be put as, though meticulous, hardworking and dedicated yet, do not 'let go' of their past emotions of hurt, feelings of corniness, never ever forgetting insults, reprimands; 'Hoard' things, overcautious, obsessed with their security system.
For info log on to www.healthlibrary.com.
The document discusses the culture of the Albatrosians and what can be learned from it. It notes that in their culture, women have a higher position than men and are more closely connected to the earth. Only women are allowed to remove their shoes and kneel on the earth. When eating, men must wash themselves first and eat/drink first to ensure the food is safe. The Albatrosian society appreciates silence, seriousness, and is peaceful, open to foreigners and tolerant. Their ceremonies stem from tradition and are considered very normal within their culture. The document encourages understanding that one's own culture influences observations and that what is normal differs across cultures.
1. The document provides instructions for virtual classroom rules and etiquette, including keeping cameras on, muting microphones when not speaking, and using the chat box to request to speak.
2. It then discusses different types of plants, categorizing them into those without seeds like algae and ferns, and those with seeds like flowering plants and conifers.
3. The document teaches about comparing and contrasting, providing examples and signal words to identify similarities and differences between objects or entities. It emphasizes the importance of this skill for developing writing and communication abilities.
1. Drug abuse has become a serious social problem in Indonesian society, affecting people of all ages. Though not immediately apparent, drug problems have penetrated all levels of society like an iceberg.
2. Environmental factors such as easy drug access, poor family communication, authoritarian parenting, peer pressure, and an unsafe school environment can contribute to drug use.
3. Common drugs include opiates, marijuana, amphetamines, cocaine, alcohol, and benzodiazepines. Excessive use leads to negative physical and psychological effects like euphoria, anxiety, insomnia, and organ damage.
Sept 2013 edition of whispering soul newsletterBetty Cosgrave
This document discusses the psychology of happiness. It states that happiness is commonly considered the main way to evaluate how well one's life is going. While money cannot buy happiness, regular exercise, close relationships, meaningful work, and achieving goals can increase happiness. The document also provides a 10-point list of actions people can take to improve their happiness, such as not pursuing happiness directly, being reflective, and following a healthy lifestyle.
The document discusses the themes of solitude, loneliness, and finding strength within oneself. It provides quotes on how loneliness can be overcome through solitude and learning to value one's own company. Solitude allows one to gain self-awareness and compassion for others, while loneliness leads to using others as escapes from being alone. True companionship is being alone together, and one must learn to live alone even when with others.
This document provides information about cannabis/marijuana, its effects, dependency, and quitting usage. It discusses cannabis's active chemicals and how they affect the brain. Both short-term effects like relaxation and long-term risks like increased anxiety and depression are described. Symptoms of cannabis dependency and strategies for quitting like reducing usage gradually or stopping cold turkey are presented over multiple sections.
Admissions Essay Editing - Fast And Af. Online assignment writing service.Mellisa Hedeen
Meredith Monk's piece Early Morning Melody exhibits many minimalist techniques. The song features isolated vocals that repeat a simple melody over four iterations. Monk strips the song down to just her voice, which she uses to sing the same melodic phrase. This repetition of a single melodic idea is a hallmark of minimalist music.
Though the melody repeats, the song does not feel redundant. Each repetition allows the listener to interpret the piece differently based on the lyrics and their own imagination. The lyrics conjure images of waking up early in the morning and going about a routine
Breast cancer: Post menopausal endocrine therapyDr. Sumit KUMAR
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
Nutritional deficiency Disorder are problems in india.
It is very important to learn about Indian child's nutritional parameters as well the Disease related to alteration in their Nutrition.
Travel vaccination in Manchester offers comprehensive immunization services for individuals planning international trips. Expert healthcare providers administer vaccines tailored to your destination, ensuring you stay protected against various diseases. Conveniently located clinics and flexible appointment options make it easy to get the necessary shots before your journey. Stay healthy and travel with confidence by getting vaccinated in Manchester. Visit us: www.nxhealthcare.co.uk
Summer is a time for fun in the sun, but the heat and humidity can also wreak havoc on your skin. From itchy rashes to unwanted pigmentation, several skin conditions become more prevalent during these warmer months.
Discover the benefits of homeopathic medicine for irregular periods with our guide on 5 common remedies. Learn how these natural treatments can help regulate menstrual cycles and improve overall menstrual health.
Visit Us: https://drdeepikashomeopathy.com/service/irregular-periods-treatment/
STUDIES IN SUPPORT OF SPECIAL POPULATIONS: GERIATRICS E7shruti jagirdar
Unit 4: MRA 103T Regulatory affairs
This guideline is directed principally toward new Molecular Entities that are
likely to have significant use in the elderly, either because the disease intended
to be treated is characteristically a disease of aging ( e.g., Alzheimer's disease) or
because the population to be treated is known to include substantial numbers of
geriatric patients (e.g., hypertension).
Debunking Nutrition Myths: Separating Fact from Fiction"AlexandraDiaz101
In a world overflowing with diet trends and conflicting nutrition advice, it’s easy to get lost in misinformation. This article cuts through the noise to debunk common nutrition myths that may be sabotaging your health goals. From the truth about carbohydrates and fats to the real effects of sugar and artificial sweeteners, we break down what science actually says. Equip yourself with knowledge to make informed decisions about your diet, and learn how to navigate the complexities of modern nutrition with confidence. Say goodbye to food confusion and hello to a healthier you!
Nano-gold for Cancer Therapy chemistry investigatory projectSIVAVINAYAKPK
chemistry investigatory project
The development of nanogold-based cancer therapy could revolutionize oncology by providing a more targeted, less invasive treatment option. This project contributes to the growing body of research aimed at harnessing nanotechnology for medical applications, paving the way for future clinical trials and potential commercial applications.
Cancer remains one of the leading causes of death worldwide, prompting the need for innovative treatment methods. Nanotechnology offers promising new approaches, including the use of gold nanoparticles (nanogold) for targeted cancer therapy. Nanogold particles possess unique physical and chemical properties that make them suitable for drug delivery, imaging, and photothermal therapy.
5-hydroxytryptamine or 5-HT or Serotonin is a neurotransmitter that serves a range of roles in the human body. It is sometimes referred to as the happy chemical since it promotes overall well-being and happiness.
It is mostly found in the brain, intestines, and blood platelets.
5-HT is utilised to transport messages between nerve cells, is known to be involved in smooth muscle contraction, and adds to overall well-being and pleasure, among other benefits. 5-HT regulates the body's sleep-wake cycles and internal clock by acting as a precursor to melatonin.
It is hypothesised to regulate hunger, emotions, motor, cognitive, and autonomic processes.
Spontaneous Bacterial Peritonitis - Pathogenesis , Clinical Features & Manage...Jim Jacob Roy
In this presentation , SBP ( spontaneous bacterial peritonitis ) , which is a common complication in patients with cirrhosis and ascites is described in detail.
The reference for this presentation is Sleisenger and Fordtran's Gastrointestinal and Liver Disease Textbook ( 11th edition ).
3. Natrum comes under 3rd row and 1st column in
periodic table.
Natrum comes under
group 1.
C/S ALKALI METALS.
The alkali metals are soft
and easy to cut.
They have low melting
points which decreases
down the group.
Reactivity of the metals
increases down the
group.
4. As you can see the outer shell of sodium has only one
electron, which is responsible for the reactivity of the
sodium.
In order to achieve the
noble gas configuration,
sodium can give up it’s
last electron to make a
bond with chlorine.
5. Dr. R. Sankaran’s
view
In Na+ stress is on individual
relation on 1:1 basis whereas
in kali it is more reactive and
has 1: group/ family.
● Dr Sankaran examines this group from their position in the
periodic table. NATRUM, KALI, MAGNESIUM & CALCIUM are
cations and they have the tendency to give one electron to
become stable. Because of this feeling, they have the feeling
of being incomplete.
● The anions on the other hand, have excess electrons; they
have to accept more electrons to be stable. Such elements (
such as phosphorus, sulphur, etc.) too feel the need for a
relationship, but they have to make a lot of effort to keep the
relationship.
7. USES
It is used in the manufacture of sodium cyanide & sodium
peroxide, synthetic detergents, sodium hydride and
sodium borohydride.
Used in production of dyes, synthesis of perfumes, organic
reductions.
The most important and familiar sodium compound is sodium
chloride, or common salt, NaCl.
Its use in the manufacture of chlorine and sodium hydroxide by
electrolytic decomposition and in the production of sodium
carbonate (Na2CO3) by the Solvay process.
8. The 5 Best Sources of Sodium in Food
BEETROOT:-
pickled beetroot has highest amount of 200mg compared to raw and canned beets.
Beetroot also contains potassium, which helps curb the body’s adverse effects of high sodium.
Therefore, it is a healthy yet great choice to provide your body with its sodium requirement to
regulate blood pressure.
OLIVES
TOMATO JUICE
COTTAGE CHEESE
BAKED BEANS
9. Let’s see SODIUM in detail.
It is a soft, white metal, can be cut with a knife.
Sodium when burns in oxygen gives
12. 1. Sodium is highly reactive because of its electronic configuration.
Stability → → → lose its electron →→ → to combine with an anion to
form an element.
This shows their extreme dependency and need for one to one relationship.
2. It is very difficult to find Na+.
Naturally it is present in crystalline form, mainly by bonding with
chlorine as SODIUM CHLORIDE.
Therefore, natrums are completely dependent on their partners to give
them identity.
They need lots of love, care and nurturing from partner.
13. 3. As salt gives flavour to our food excess of which can also harm us.
Salt needs to be carefully added in the dish. →→→ exactly like this is the
mind of natrums….
This is the basic idea behind their DIGNITY. They think without them
nothing can happen.
4. Because of their strong bond with partner, they will do whatever
their partner wants, decides and chooses for them.
Natrum looks for a kind of romantic love where they expect the other
person to know it and fulfill it. THEY EXPECT LOVE.
14. Sodium plays an important role in cell injury.
When an injury occurs
sodium moves into the
cell.
Causing rise intra cellular
sodium levels.
Sodium holds water
along with this.
This explain the introvert,
reserved, protective
nature of natrum.
This also explains *their
tendency to hold things
up.*
15. Dr Scholten has adopted group analysis method to
understand compound salts.
He says that the essential
themes of natrum are:
• Grief
• Being closed and alone
• Restriction, denial and
prohibition.
• Sensitive and vulnerable
• Inclination to withdrawal
(model).
They get stuck in past.
They keep their problems
inside; they are closed and do
not feel like talking.
They can also have the feeling
that it is forbidden to be happy.
They feel much have been taken
from them (relate with slide -4)
16. As per him…
In group analysis, Dr Scholten links muriaticum to mother and carbonicum to father. His
concept for natrum mur are:-
NATRUM MURIATICUM
Sadness & depression self- pity
Closed, alone care
Restriction nurturing
Denial, forbidden mother
Sensitive attention
Holding on self awareness.
No mother and no care; thus the delusion that his mother is dead. Nat mur could be
needed for mothers who are strict and cold; who feel that it is bad to spoil children.
Nat mur is the one which has the feeling of being alone in the world.
17. NATRUM CARBONICUM
Sadness & depression giving meaning
Closed, alone stating values
Restriction self- worth
Denial, forbidden dignity
Sensitive shyness
Holding on father/worker
*would rather be alone in dignity than feel denied by others.
*has no father, abandoned by father.
*Forsaken feeling
18. NATRUM PHOSPHORICUM
Sadness & depression communicative
Closed, alone sympathetic
Restriction friends, acquaintance, neighbours
Denial, forbidden Brothers
Sensitive homesickness
Holding on curiosity/ travel
*Communication is forbidden- they walk around with secret.
1. Feeling that they have something which they are not allowed to share with others,
thus they carry the heavy burden of the secret.
2. Communication is very sensitive and refined; could mean culturally delicate with
respect to other people’s feelings.
3. Feel lonely and depressed as they go their own way.
4. This could be the situation: an only child, not having friends, loss of friend, moving
house.
19. NATRUM NITRICUM
Sadness & depression enjoyment
Closed, alone need for space, expansion
Restriction going out
Denial, forbidden congestion, explosive
Sensitive tension
Holding on relaxation
• Theme is not being able or not being allowed to enjoy life. Their attitude is
puritan. “Enjoyment is sinful”.
• People who enjoy things only when they are alone.
20. NATRUM FLUORATUM
Sadness & depression glamour & glitter
Closed, alone Money, cars, clothes
Restriction sex
Denial, forbidden Hard, fast, hurried
Sensitive psychopathic
Holding on superficial contacts.
● First theme is forbidden sex & most extreme taboo is incest. This makes it difficult, if not
impossible for them to talk about it and have to deal with it themselves.
● Variations of theme: feel alone in their sexual experiences.
● The sexual act may bring up such feelings of loneliness that they may start crying; eventually
they like to avoid this contact.
● They feel alone in their glittering career though build good contacts to relieve this loneliness.
● They believe such contacts are only superficial & meaningless;
● hence remain reserved.
21. As per Dr. Roberts
“The general state of mental depression and gloominess characterizes the NATRUM GROUP.
It seems as if they almost delight in making themselves and others miserable by looking on
the dark side; by their strong aversion to consolation; and their alternating gaiety and
gloom.
Profound action is seen on:
1. mental state
2. physical functions
3. chemistry of fluids
4. pathology of organs.”
32. ⮚Great anxiety from downward
motion. When going downstairs
there is anxiety of keeping
balance or harmony.
⮚There is a marked desire to
form and maintain a
relationship especially on a one
to one level.
36. ⮚They are very closed, keep
their problems inside, do not
feel like talking about it, feeling
of being alone and they carry
the burden of their sadness
alone.
⮚Unable to form a
relationship.
40. ⮚They have the feeling that it
is forbidden to be happy, that
they are not allowed to
experience this. Thus, they
can be very pessimistic
persons.
41.
42. ⮚Sensitivity is the
characteristic feature of
Natrums.
⮚They are very sensitive to
noise, to music.
⮚Any unexpected thing
may hurt them easily.
43.
44. ⮚Depressed and easily irritable.
This feature is particularly seen
after dinner which is usually the
heavy meal.
⮚This hypochondriasis increases
with the degree of constipation
and decreases with the degree of
digestion.
45.
46. ⮚Natrum people are very
much aware of their
emotions. If they have
been hurt, they tend to
not forget. They are very
emotional especially
concerning relationships.
52. The natrum element: as mentioned before, they are highly reactive they are
more sensitive as to others feelings and what others say about them which
make them feel depressed.
Bad effects of disappointment in love, from grief.
The muriatic element: this brings the rage and revengeful attitude, anger,
irritability, forgetfulness, apprehensive
Natrum muriaticum is the combination of symptoms of both these elements:
1. Ailments occur from unrequited affections, mood swings uncontrollable
laughter followed by sadness and weeping. Broods over the past, cannot
bring oneself into the state of being joyful
2. Extremely forgetful, loses the thread of conversation, forgets what she was
going to say
3. Apprehension about the future
4. Peevish irritability especially in children
5. Easily carried away to anger, every trifle excites him to anger, hypochondriac
54. The natrum element: same as previously mentioned, sadness, grief,
disappointed love
The carbon element: anxiety, timidity, irresolution, disposition to be
frightened, aversion to labour, embarrassments in society
Natrum carbonicum: when the elements are combined:
1. Fear from slightest noise, even to the rattling of paper causes
palpitation, from slam of the door, with nervous weakness
2. Aversion to mankind, to society, to strangers
3. Weeping, melancholy, suicidal thoughts especially when listening to
music
4. Music causes great sadness which increases to religious insanity.
56. The natrum element: sadness, grief, disappointed love
The Phosphorous element: excitable to a level of ecstasy, fear,
apprehension, anxiety, startles easily, apathy, sad, tired easily, high sense
of imagination
Natrum phosphoricum:
1. Anxiety at night, in bed, frightened easily
2. Delusions, imagines he sees dead people, that he has typhoid etc.
3. Indifferent to everything even to his own family. Becomes sad
mainly in the evening
4. Indisposed to talk, grows timid and bashful, mental work seems
impossible
5. Great prostration of mind occurs, forgetfulness
58. Natrum element– sad, despondent, forgetful, melancholy, hysteria, contradiction
aggravates, morning aggravation, hot patient
Arsenicum element– anxiety, fear, restlessness, midnight aggravation, chilly patient
Natrum ars:
1. Easily frightened, startles easily by noise
2. Very forgetful, aversion to mental work
3. Indifferent to all joy
4. Hysterical, laughing, mirthful followed by sadness
5. Fear of impending disease, evil forebodings
6. Anger at trifles, furious from contradiction
7. Suspicious, disturbed by conversation of people
8. < morning, midnight, cold air
9. > warm open air
10.Here the mental symptoms are all mild as when compared to these remedies
separately.
60. Natrum element: sad, gloomy, fearful, easily startles
Sulphur element: dullness and confusion of mind, indisposed to
everything- to talking, work, motion, laziness.
Natrum sulph:
1. Lively music saddens
2. Melancholy with periodical attacks of mania
3. Suicidal tendency, must exercise restraint
4. Dislikes to speak or to be spoken to
5. Mental troubles comes from a blow to the head
6. Fear of crowd, of evil, of people
7. Starting from fright or noise or in sleep.
62. ❖All Natrums show
alteration of blood
causing a condition of
Anaemia &
leucocytosis; they also
show periodicity of
mucous, cutaneous,
serous manifestations.
63. ❖All complaints arise every summer
❖ In hot weather, electric changes in the atmosphere
or direct rays of sun give rise to various elements &
complaints
64. ❖Prolonged taking of excessive salt causes profound
nutritive changes in various systems. There arise
symptoms of salt retention as evidenced by dropsy’s
& oedema.
❖General debility is main feature of Natrum Group.
❖ Physic: thin
❖ Temperature :warm, sea
❖Time : <11 a.m.
67. Natrum group remedies are frequently indicated for
headaches, especially those caused or worsened by
emotional stress, grief, hormonal imbalances, or
exposure to sunlight. The headaches may be
throbbing, pulsating, or bursting in nature and may be
accompanied by a sense of heaviness or tightness in
the head.
69. Dryness is a key characteristic of the Natrum group
remedies. This can manifest as dry skin, dry lips, dry
mouth or throat, dry cough, dry eyes, or dryness of
mucous membranes. The dryness may be aggravated
by exposure to dry or cold weather.
71. People who require Natrum group remedies often have
specific cravings and aversions. They may have a
strong craving for salty foods or a desire for unusual
substances like chalk, dirt, or raw potatoes.
Conversely, they may have aversions to certain foods
or have a dislike for salt.
73. Natrum group remedies can be indicated for various
digestive complaints. This may include indigestion,
acidity, flatulence, constipation with dry, hard stools, or
diarrhea with watery stools.
75. Women who require Natrum group remedies may
experience menstrual irregularities, such as heavy or
scanty periods, delayed or suppressed menses, or
symptoms aggravated before or after menstruation.
They may also experience emotional sensitivity or
sadness during menstruation.
77. Natrum group remedies are often prescribed for skin
conditions, such as dry and cracked skin, eczema,
herpes, hives, or cold sores. The skin symptoms may
be aggravated by exposure to the sun or emotional
stress.
79. Individuals who benefit from Natrum group remedies
may have a tendency toward allergies or
hypersensitivity. This may manifest as allergies to
specific substances, such as pollen, dust, or certain
foods, leading to symptoms like sneezing, itching,
watery eyes, or skin rashes.
81. ➢Headaches, especially throbbing headaches aggravated by
exposure to the sun
➢Dryness of mucous membranes, including dry mouth and
lips
➢Craving for salt and salty foods
➢Cold sores or herpes eruptions on the lips or around the
mouth
➢Worsening of symptoms or emotional sensitivity during
menstruation
➢Watery or clear nasal discharge, sneezing, and hay fever-like
symptoms
83. ➢Weakness and fatigue, especially in the morning
➢Sensitivity to heat and a tendency to be easily overheated
➢Digestive issues such as indigestion, bloating, and flatulence
➢Craving for eggs and other rich, fatty foods
➢Skin problems, including dryness, itching, and eruptions
aggravated by warmth
➢Joint pains, especially in the small joints, that are worse from
dampness
85. ➢Acidity and digestive disturbances, including sour belching
and heartburn
➢Indigestion caused by consuming fatty or rich foods
➢Joint pains with an excess of uric acid, leading to gout-like
symptoms
➢Cravings for highly acidic or sour foods and drinks
➢Yellowish coating on the tongue or sour taste in the mouth
➢Symptoms worsened by mental exertion or emotional stress
87. ➢Anxiety and restlessness with a strong fear of death
➢Indigestion and gastric complaints, including burning pain in
the stomach
➢Asthma and breathing difficulties, worsened by lying down
➢Skin conditions such as eczema, psoriasis, or dry, scaly
eruptions
➢Cravings for cold drinks or ice-cold water
➢Fatigue and weakness, both physical and mental
89. ➢Liver complaints and symptoms associated with a sluggish
liver
➢Worsening of symptoms in damp or rainy weather
➢Yellowish-greenish discharges or secretions from various body
parts
➢Allergies and asthma triggered by dampness or mold
➢Fatigue and a feeling of heaviness in the limbs
➢Water retention or swelling, especially in the lower extremities