This document outlines the roles and effects of myofunctional appliances and cartilage in orthodontics, detailing types of cartilage, methods of ossification, and the influence of orthodontic forces on mandibular growth. It also discusses various functional appliances, their design, indications for use, and management procedures, emphasizing the importance of timing in treatment. Additionally, it presents different treatment methodologies and the effects on skeletal and dental growth, concluding that compliance with removable appliances is critical for achieving significant corrective outcomes.