MEDIAL CALCINOSIS

1. Monckeberg’s
Arteriosclerosis

2. It is also known as medial calcific
sclerosis.
Arteriosclerosis is thickening and loss of
elasticity of arterial walls.
In it Calcific deposits which is a type of
dystrophic calcification in the tunica
media of medium sized arteries seen.

3. It is a physiological phenomenon
usually seen in persons over 50
years of age.
Mostly affected vessels are
muscular arteries of extremities
and arteries supplying female
genital tract.

4. Medial calcification is often an
incidental finding in x ray of affected
sites.
Grossly the involved blood vessels
undergoes calcification and thickening
which can be palpated for peripheral
vessels.
It produces pipestem like rigid tube
without causing narrowing of lumen.

5. Microscopically Monckeberg’s
arteriosclerosis is characterized by
deposits of calcium salts in the media in
the form of concentric blue rings or
basophilic coarse granules without
associated inflammatory reaction.
Intima and adventitia remain intact.

7. Thank
you