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microscope made by Antonie van Leeuwenhoek
lens magnifying an object
An engraving of the microscope used by Robert Hooke.
Hooke, Robert: cork cell structure and sprig of sensitive plant Robert Hooke’s drawings of the cellular structure of cork and a sprig of sensitive plant from Micrographia (1665). Oxford Science Library/Heritage-Images
compound microscope
Light microscopy image of a glomerulus demonstrating negative staining for both Congo-red and thioflavin-T.
Neutrophils and red blood cells as seen by light microscopy. Cells are stained with Giemsa; cytoplasms appear pink while polylobed nuclei are purple.
A typical TEM instrument showing the electron column, the fluorescent screen and the electronic equipment.
transmission electron microscope
Thin slice of a human neutrophil observed by transmission electron microscopy. In addition to the typical three lobes of the nucleus, many granules are also observed within the cytoplasmic space.
Vibrio cholerae, the bacterium that causes cholera, shown in a false-colour transmission electron micrograph.
A typical SEM instrument, showing the electron column, sample chamber, EDS detector, electronics console, and visual display monitors.
Scanning Electron Microscope (SEM)
Pollen grains taken on an SEM
Colour-enhanced scanning electron micrograph (magnified 50×) of a bean aphid on a leaf.
Scanning electron microscope of leukemia cells (left) shown in comparison with bone marrow cells (right).

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Microscopes