Gregor Mendel conducted experiments with pea plants in the 1860s to study inheritance patterns of traits. Through his work with thousands of pea plants across generations, he discovered the fundamental principles of heredity, including that traits are controlled by discrete units (genes) which are inherited based on dominant and recessive patterns. His work established the basic rules of Mendelian genetics, including segregation and independent assortment of genes. However, his findings were not widely accepted until rediscovered in the early 1900s. The document provides details on Mendel's experiments and conclusions, as well as further concepts in genetics like incomplete dominance and codominance.
1. Mendel conducted breeding experiments with pea plants to study inheritance of traits such as flower color.
2. Through his experiments, he discovered that traits are inherited as discrete units (genes) which segregate and assort independently during reproduction according to his laws of inheritance.
3. Mendel's work laid the foundations of classical genetics although it was not widely recognized until rediscovered later.
Chapter 5 principles of inheritance and variationmohan bio
- Mendelian genetics deals with the study of heredity and variation through experiments in pea plants by Gregor Mendel.
- Mendel discovered the laws of inheritance through experiments showing traits are inherited in dominant and recessive patterns.
- His work was later combined with the chromosomal theory of inheritance which showed genes are located on chromosomes and segregate during gamete formation according to Mendel's laws.
Gregor Mendel conducted experiments breeding pea plants in the 1850s-1860s to understand heredity. By tracking inherited traits over multiple generations, he discovered that traits are transmitted by discrete factors (now known as genes) and follow predictable patterns. His work established the foundations of classical genetics, including the laws of segregation and independent assortment. Though his work was largely ignored at first, it was rediscovered in 1900 and revolutionized understanding of inheritance.
Gregor Johann Mendel was an Augustinian monk who conducted genetic experiments with pea plants in the 1850s and 1860s. He presented his findings in 1865, which proposed basic principles of inheritance now known as Mendel's laws of inheritance. However, his work was not widely recognized until the 1900s. Mendel's experiments involved breeding thousands of pea plants and tracking discrete traits like flower color, seed texture, and pod shape over multiple generations. His results showed dominant and recessive traits are inherited in predictable ratios and segregate independently of one another. Mendel's experiments were groundbreaking in establishing genetics as a science.
MENDELE'S EXPERIMNENT AND TERMINOLOGY, BY MR. DINABANDHU BARAD, MSC TUTOR, DEPARTMENT OF PEDIATRIC, SUM NURSING COLLEGE, SIKSHA 'O' ANUSANDHAN DEEMED TO BE UNIVERSITY
This document provides an overview of Mendelian genetics. It discusses:
- Gregor Mendel, the father of genetics, who discovered the basic principles of heredity through pea plant experiments in the mid-1800s.
- Key genetic terminology like traits, heredity, genetics, alleles, genotype and phenotype.
- Mendel's experiments on monohybrid and dihybrid crosses, which showed that traits are inherited in predictable ratios and follow the laws of dominance and segregation.
- Mendel's laws of inheritance: dominance, segregation, and independent assortment. His work established the foundation of modern genetics.
This document provides an overview of theoretical genetics concepts including:
1) It defines key genetics terms and concepts discovered by Gregor Mendel through his pea plant experiments, including genes, alleles, dominance, segregation, and Punnett squares.
2) It explains Mendel's principles of inheritance including segregation and independent assortment of alleles and how this determines genotype and phenotype probabilities.
3) It discusses extensions of Mendelian genetics including co-dominance, multiple alleles, genetic linkage, sex-linkage, and examples like blood types and hemophilia.
Gregor Mendel conducted experiments with pea plants in the 1860s to study inheritance patterns. He found that inherited traits are determined by discrete units (now known as genes and alleles) that segregate and assort independently during reproduction. Through his experiments with monohybrid and dihybrid crosses, Mendel deduced the laws of segregation and independent assortment. His results followed predictable ratios and supported the rules of probability. Later experiments using testcrosses confirmed Mendel's findings and allowed determination of genotypes.
1. Mendel conducted breeding experiments with pea plants to study inheritance of traits such as flower color.
2. Through his experiments, he discovered that traits are inherited as discrete units (genes) which segregate and assort independently during reproduction according to his laws of inheritance.
3. Mendel's work laid the foundations of classical genetics although it was not widely recognized until rediscovered later.
Chapter 5 principles of inheritance and variationmohan bio
- Mendelian genetics deals with the study of heredity and variation through experiments in pea plants by Gregor Mendel.
- Mendel discovered the laws of inheritance through experiments showing traits are inherited in dominant and recessive patterns.
- His work was later combined with the chromosomal theory of inheritance which showed genes are located on chromosomes and segregate during gamete formation according to Mendel's laws.
Gregor Mendel conducted experiments breeding pea plants in the 1850s-1860s to understand heredity. By tracking inherited traits over multiple generations, he discovered that traits are transmitted by discrete factors (now known as genes) and follow predictable patterns. His work established the foundations of classical genetics, including the laws of segregation and independent assortment. Though his work was largely ignored at first, it was rediscovered in 1900 and revolutionized understanding of inheritance.
Gregor Johann Mendel was an Augustinian monk who conducted genetic experiments with pea plants in the 1850s and 1860s. He presented his findings in 1865, which proposed basic principles of inheritance now known as Mendel's laws of inheritance. However, his work was not widely recognized until the 1900s. Mendel's experiments involved breeding thousands of pea plants and tracking discrete traits like flower color, seed texture, and pod shape over multiple generations. His results showed dominant and recessive traits are inherited in predictable ratios and segregate independently of one another. Mendel's experiments were groundbreaking in establishing genetics as a science.
MENDELE'S EXPERIMNENT AND TERMINOLOGY, BY MR. DINABANDHU BARAD, MSC TUTOR, DEPARTMENT OF PEDIATRIC, SUM NURSING COLLEGE, SIKSHA 'O' ANUSANDHAN DEEMED TO BE UNIVERSITY
This document provides an overview of Mendelian genetics. It discusses:
- Gregor Mendel, the father of genetics, who discovered the basic principles of heredity through pea plant experiments in the mid-1800s.
- Key genetic terminology like traits, heredity, genetics, alleles, genotype and phenotype.
- Mendel's experiments on monohybrid and dihybrid crosses, which showed that traits are inherited in predictable ratios and follow the laws of dominance and segregation.
- Mendel's laws of inheritance: dominance, segregation, and independent assortment. His work established the foundation of modern genetics.
This document provides an overview of theoretical genetics concepts including:
1) It defines key genetics terms and concepts discovered by Gregor Mendel through his pea plant experiments, including genes, alleles, dominance, segregation, and Punnett squares.
2) It explains Mendel's principles of inheritance including segregation and independent assortment of alleles and how this determines genotype and phenotype probabilities.
3) It discusses extensions of Mendelian genetics including co-dominance, multiple alleles, genetic linkage, sex-linkage, and examples like blood types and hemophilia.
Gregor Mendel conducted experiments with pea plants in the 1860s to study inheritance patterns. He found that inherited traits are determined by discrete units (now known as genes and alleles) that segregate and assort independently during reproduction. Through his experiments with monohybrid and dihybrid crosses, Mendel deduced the laws of segregation and independent assortment. His results followed predictable ratios and supported the rules of probability. Later experiments using testcrosses confirmed Mendel's findings and allowed determination of genotypes.
Gregor Mendel conducted experiments with pea plants in the 1860s to study patterns of inheritance. Through his experiments, he discovered that inherited traits are determined by discrete units (now known as genes) that segregate and assort independently during reproduction. Mendel's work established the laws of segregation and independent assortment, which describe how traits are inherited and passed from parents to offspring through gametes and fertilization. His findings were consistent with basic rules of probability and provided evidence that supported his theories of genetic inheritance.
Gregor Mendel conducted experiments with pea plants in the 1860s to study patterns of inheritance. Through his experiments, he discovered that inherited traits are determined by discrete units (now known as genes) that segregate and assort independently during reproduction. Mendel's work established the laws of segregation and independent assortment, which describe how traits are inherited and passed from parents to offspring through gametes and fertilization. His findings were consistent with basic rules of probability and provided evidence that supported his theories of genetic inheritance.
Gregor Mendel conducted experiments with pea plants to study inheritance of traits. He found that traits are passed from parents to offspring through discrete units called alleles, and that alleles segregate and assort independently during reproduction according to his principles of segregation and independent assortment. Mendel's discoveries established the foundations of classical genetics.
12/15/2011
1
Genetic
Mendle’s law
Patterns of Inheritance
• Mendel’s Laws
• Variations on Mendel’s Laws
• The Chromosomal Basis of Inheritance
• Sex Chromosomes and Sex-linked Genes
12/15/2011
2
The Field of Genetics has Ancient Roots
• Hippocrates (father of medicine): particles from every part of the body travel to eggs
and sperm to be passed on
• Aristotle (philosopher): ‘potential’ rather than particles to produce body features
• 19th century biologists: blending- mom and dad’s traits blend like blue and yellow paint
Hippocrates Aristotle
Experimental Genetics Began in an Abbey Garden
• Modern genetics began in 1860s
• Gregor Mendel (monk in what was then Austria- now Czech Republic)
• Parents pass on discrete, heritable factors (1866)
• Heritable factors retain their individuality for generations (no blending)
• Studied garden peas
12/15/2011
3
• In a typical breeding experiment
– Mendel mated two different, true-breeding varieties, a process called hybridization
• The true-breeding parents
– Are called the P generation
• The hybrid offspring of the P generation
– Are called the F1 generation
– F2 generation comes next
Experimental Genetics Began in an Abbey Garden
• Cross: pollinating a flower of one variety with the pollen of another variety
Mendel chose to work with peas:
– Because they are available in many varieties
– Because he could strictly control which plants mated with which
– Because he could easily start his experiments with varieties that were “true-breeding”
12/15/2011
4
Some genetic vocabulary
Character: a heritable feature, such as flower color
Trait: a variant of a character, such as purple or white flowers
Gene: a discrete unit of hereditary information consisting of a specific
DNA (nucleotide) sequence on a chromosome
Allele: alternative version of a gene
Mendel’s Law of Segregation Describes the Inheritance of a Single Characteristic
Performed monohybrid crosses (only 1 trait differs between the varieties)
• When Mendel crossed contrasting, true-breeding white and purple
flowered pea plants
» All of the offspring were purple!!!
Mendel discovered:
A ratio of about three to one (3:1)
purple to white flowers,
in the F2 generation
When Mendel crossed the F1 plants –
Many of the plants had
purple flowers, but some
had white flowers
12/15/2011
5
Mendel’s Law of Segregation Describes the Inheritance of a Single Characteristic
Mendel developed a hypothesis to explain the 3:1 inheritance pattern that he observed
among the F2 offspring
Four Parts:
1. First, alternative versions of genes account for variations in inherited characters
which are now called alleles
Allele for purple flowers
Locus for flower-color gene
Homologous
pair of
chromosomes
Allele for white flowers
Mendel’s Model for Inheritance
Four Parts:
1. First, .
Gregor Mendel conducted experiments with pea plants in the 1850s and 1860s to study inheritance of traits. Through his experiments with over 28,000 pea plants, he discovered that traits are passed from parents to offspring through discrete factors, now known as genes. Mendel identified that for each trait, organisms inherit one gene from each parent, and that some genes are dominant and will always be expressed while others are recessive and only expressed when the dominant gene is not present. His work formed the basis of classical genetics and established the laws of segregation and independent assortment.
Gregor Mendel conducted experiments with pea plants in the 19th century to study inheritance patterns of traits like seed color, pod shape, flower color, etc. He found that traits are inherited in predictable ratios and proposed Mendel's laws of inheritance. The laws of segregation, independent assortment and dominance describe how alleles separate and transmit from parents to offspring. Mendel's work established the foundations of classical genetics and heredity.
AP Biology Inheritance and chromosomal mutationsStephanie Beck
This document provides information about Gregor Mendel and his experiments with pea plants that formed the basis of classical genetics and heredity. It discusses Mendel's work with traits controlled by single genes, including his discovery of dominant and recessive alleles and his laws of segregation and independent assortment. It also describes more complex patterns of inheritance beyond simple Mendelian genetics, including incomplete dominance, codominance, multiple alleles, epistasis, pleiotropy, and polygenic and sex-linked traits. The document uses examples like coat color in cats and human genetic disorders to illustrate these concepts.
This document provides an overview of genetics and Mendelian inheritance. It discusses how Mendel conducted experiments on pea plants to develop the principles of heredity, including his laws of inheritance. Mendel showed that traits are inherited as discrete units (genes) that assort independently, with one trait (dominant) masking the expression of another (recessive) trait. His work demonstrated monohybrid and dihybrid crosses, and laid the foundations for modern genetics.
Principles of Inheritance, Class 12 CBSEblessiemary
This document provides information about principles of inheritance and variation in genetics. It discusses key topics including:
- Genetics deals with inheritance and variation from parents to offspring. Variation results in offspring differing from parents.
- Gregor Mendel conducted experiments with pea plants in the 1800s and established the principles of heredity, including dominance, segregation, independent assortment. He demonstrated genes are passed from parents to offspring in predictable ratios.
- Chromosomal theory of inheritance later explained that genes are located on chromosomes and segregate during gamete formation according to Mendel's laws. The work of Morgan, Sutton, and Boveri supported this theory through experimentation.
Gregor Mendel conducted experiments breeding pea plants starting in 1854. He discovered that traits are inherited as discrete units (now called genes) that are passed unchanged from parents to offspring. Through his experiments with monohybrid and dihybrid crosses, Mendel deduced his two laws of inheritance: 1) The Law of Segregation states that alleles segregate and sort independently into gametes, and 2) The Law of Independent Assortment states that genes assort independently of one another when gametes are formed.
Genetics is the study of heredity and genes. Gregor Mendel conducted experiments with pea plants in the 1800s that formed the basis of genetics. Through his work, he discovered the principles of inheritance, including that traits are determined by units now called genes, genes occur in different forms called alleles, dominant alleles mask recessive alleles, and alleles assort independently during gamete formation. Mendel's principles can be used to predict the results of genetic crosses and the inheritance of traits.
Gregory Mendel was an Austrian monk who conducted experiments in the 1850s on the inheritance of traits in pea plants. Through careful experimentation and statistical analysis, Mendel discovered that traits are passed from parents to offspring through discrete units called genes. He found that some genes, called dominant genes, mask the effects of other recessive genes. Mendel's work established the foundations of genetics and heredity through his principles of inheritance and experiments using Punnett squares.
This document provides an overview of Gregor Mendel's experiments with pea plants and the principles of inheritance he discovered. It discusses Mendel's work crossbreeding pea plants and tracking inherited traits over generations. From this work, Mendel discovered his Laws of Inheritance - the principles of dominance, segregation, independent assortment, and the difference between homozygous and heterozygous traits. The document explains Mendel's experiments and how he used this to develop theories about how traits are passed from parents to offspring through discrete units now known as genes.
Gregor Mendel was an Austrian monk who is considered the father of genetics. In the mid-1800s, he conducted experiments breeding pea plants and discovered the basic principles of heredity. He found that traits are passed from parents to offspring through discrete factors that we now call genes. Mendel's work laid the foundation for modern genetics and showed that inheritance follows specific biological rules.
Genetics is a branch of biology concerned with the study of genes, genetic variation, and heredity in organisms. Though heredity had been observed for millennia, Gregor Mendel, Moravian scientist and Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene.
Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded beyond inheritance to studying the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the context of a population. In science and especially in mathematical studies, a variational principle is one that enables a problem to be solved using calculus of variations, which concerns finding functions that optimize the values of quantities that depend on those functions.
Females have two X chromosomes, while males have one X and one Y chromosome. Females need two X chromosomes because one of the two X chromosomes in each cell of a female is randomly inactivated very early in development. This process, called X-inactivation or lyonization, ensures that females, like males, have only one active X chromosome per cell. It balances gene expression between males and females.
Gregor Mendel conducted experiments with pea plants to establish the basic laws of inheritance. He found that traits from parents separate and recombine in predictable ways when passed to offspring. Mendel determined that traits are determined by discrete factors, now known as genes, which are inherited independently of each other. His work established the fundamental rules of genetics and heredity.
A Visual Guide to 1 Samuel | A Tale of Two HeartsSteve Thomason
These slides walk through the story of 1 Samuel. Samuel is the last judge of Israel. The people reject God and want a king. Saul is anointed as the first king, but he is not a good king. David, the shepherd boy is anointed and Saul is envious of him. David shows honor while Saul continues to self destruct.
Gregor Mendel conducted experiments with pea plants in the 1860s to study patterns of inheritance. Through his experiments, he discovered that inherited traits are determined by discrete units (now known as genes) that segregate and assort independently during reproduction. Mendel's work established the laws of segregation and independent assortment, which describe how traits are inherited and passed from parents to offspring through gametes and fertilization. His findings were consistent with basic rules of probability and provided evidence that supported his theories of genetic inheritance.
Gregor Mendel conducted experiments with pea plants in the 1860s to study patterns of inheritance. Through his experiments, he discovered that inherited traits are determined by discrete units (now known as genes) that segregate and assort independently during reproduction. Mendel's work established the laws of segregation and independent assortment, which describe how traits are inherited and passed from parents to offspring through gametes and fertilization. His findings were consistent with basic rules of probability and provided evidence that supported his theories of genetic inheritance.
Gregor Mendel conducted experiments with pea plants to study inheritance of traits. He found that traits are passed from parents to offspring through discrete units called alleles, and that alleles segregate and assort independently during reproduction according to his principles of segregation and independent assortment. Mendel's discoveries established the foundations of classical genetics.
12/15/2011
1
Genetic
Mendle’s law
Patterns of Inheritance
• Mendel’s Laws
• Variations on Mendel’s Laws
• The Chromosomal Basis of Inheritance
• Sex Chromosomes and Sex-linked Genes
12/15/2011
2
The Field of Genetics has Ancient Roots
• Hippocrates (father of medicine): particles from every part of the body travel to eggs
and sperm to be passed on
• Aristotle (philosopher): ‘potential’ rather than particles to produce body features
• 19th century biologists: blending- mom and dad’s traits blend like blue and yellow paint
Hippocrates Aristotle
Experimental Genetics Began in an Abbey Garden
• Modern genetics began in 1860s
• Gregor Mendel (monk in what was then Austria- now Czech Republic)
• Parents pass on discrete, heritable factors (1866)
• Heritable factors retain their individuality for generations (no blending)
• Studied garden peas
12/15/2011
3
• In a typical breeding experiment
– Mendel mated two different, true-breeding varieties, a process called hybridization
• The true-breeding parents
– Are called the P generation
• The hybrid offspring of the P generation
– Are called the F1 generation
– F2 generation comes next
Experimental Genetics Began in an Abbey Garden
• Cross: pollinating a flower of one variety with the pollen of another variety
Mendel chose to work with peas:
– Because they are available in many varieties
– Because he could strictly control which plants mated with which
– Because he could easily start his experiments with varieties that were “true-breeding”
12/15/2011
4
Some genetic vocabulary
Character: a heritable feature, such as flower color
Trait: a variant of a character, such as purple or white flowers
Gene: a discrete unit of hereditary information consisting of a specific
DNA (nucleotide) sequence on a chromosome
Allele: alternative version of a gene
Mendel’s Law of Segregation Describes the Inheritance of a Single Characteristic
Performed monohybrid crosses (only 1 trait differs between the varieties)
• When Mendel crossed contrasting, true-breeding white and purple
flowered pea plants
» All of the offspring were purple!!!
Mendel discovered:
A ratio of about three to one (3:1)
purple to white flowers,
in the F2 generation
When Mendel crossed the F1 plants –
Many of the plants had
purple flowers, but some
had white flowers
12/15/2011
5
Mendel’s Law of Segregation Describes the Inheritance of a Single Characteristic
Mendel developed a hypothesis to explain the 3:1 inheritance pattern that he observed
among the F2 offspring
Four Parts:
1. First, alternative versions of genes account for variations in inherited characters
which are now called alleles
Allele for purple flowers
Locus for flower-color gene
Homologous
pair of
chromosomes
Allele for white flowers
Mendel’s Model for Inheritance
Four Parts:
1. First, .
Gregor Mendel conducted experiments with pea plants in the 1850s and 1860s to study inheritance of traits. Through his experiments with over 28,000 pea plants, he discovered that traits are passed from parents to offspring through discrete factors, now known as genes. Mendel identified that for each trait, organisms inherit one gene from each parent, and that some genes are dominant and will always be expressed while others are recessive and only expressed when the dominant gene is not present. His work formed the basis of classical genetics and established the laws of segregation and independent assortment.
Gregor Mendel conducted experiments with pea plants in the 19th century to study inheritance patterns of traits like seed color, pod shape, flower color, etc. He found that traits are inherited in predictable ratios and proposed Mendel's laws of inheritance. The laws of segregation, independent assortment and dominance describe how alleles separate and transmit from parents to offspring. Mendel's work established the foundations of classical genetics and heredity.
AP Biology Inheritance and chromosomal mutationsStephanie Beck
This document provides information about Gregor Mendel and his experiments with pea plants that formed the basis of classical genetics and heredity. It discusses Mendel's work with traits controlled by single genes, including his discovery of dominant and recessive alleles and his laws of segregation and independent assortment. It also describes more complex patterns of inheritance beyond simple Mendelian genetics, including incomplete dominance, codominance, multiple alleles, epistasis, pleiotropy, and polygenic and sex-linked traits. The document uses examples like coat color in cats and human genetic disorders to illustrate these concepts.
This document provides an overview of genetics and Mendelian inheritance. It discusses how Mendel conducted experiments on pea plants to develop the principles of heredity, including his laws of inheritance. Mendel showed that traits are inherited as discrete units (genes) that assort independently, with one trait (dominant) masking the expression of another (recessive) trait. His work demonstrated monohybrid and dihybrid crosses, and laid the foundations for modern genetics.
Principles of Inheritance, Class 12 CBSEblessiemary
This document provides information about principles of inheritance and variation in genetics. It discusses key topics including:
- Genetics deals with inheritance and variation from parents to offspring. Variation results in offspring differing from parents.
- Gregor Mendel conducted experiments with pea plants in the 1800s and established the principles of heredity, including dominance, segregation, independent assortment. He demonstrated genes are passed from parents to offspring in predictable ratios.
- Chromosomal theory of inheritance later explained that genes are located on chromosomes and segregate during gamete formation according to Mendel's laws. The work of Morgan, Sutton, and Boveri supported this theory through experimentation.
Gregor Mendel conducted experiments breeding pea plants starting in 1854. He discovered that traits are inherited as discrete units (now called genes) that are passed unchanged from parents to offspring. Through his experiments with monohybrid and dihybrid crosses, Mendel deduced his two laws of inheritance: 1) The Law of Segregation states that alleles segregate and sort independently into gametes, and 2) The Law of Independent Assortment states that genes assort independently of one another when gametes are formed.
Genetics is the study of heredity and genes. Gregor Mendel conducted experiments with pea plants in the 1800s that formed the basis of genetics. Through his work, he discovered the principles of inheritance, including that traits are determined by units now called genes, genes occur in different forms called alleles, dominant alleles mask recessive alleles, and alleles assort independently during gamete formation. Mendel's principles can be used to predict the results of genetic crosses and the inheritance of traits.
Gregory Mendel was an Austrian monk who conducted experiments in the 1850s on the inheritance of traits in pea plants. Through careful experimentation and statistical analysis, Mendel discovered that traits are passed from parents to offspring through discrete units called genes. He found that some genes, called dominant genes, mask the effects of other recessive genes. Mendel's work established the foundations of genetics and heredity through his principles of inheritance and experiments using Punnett squares.
This document provides an overview of Gregor Mendel's experiments with pea plants and the principles of inheritance he discovered. It discusses Mendel's work crossbreeding pea plants and tracking inherited traits over generations. From this work, Mendel discovered his Laws of Inheritance - the principles of dominance, segregation, independent assortment, and the difference between homozygous and heterozygous traits. The document explains Mendel's experiments and how he used this to develop theories about how traits are passed from parents to offspring through discrete units now known as genes.
Gregor Mendel was an Austrian monk who is considered the father of genetics. In the mid-1800s, he conducted experiments breeding pea plants and discovered the basic principles of heredity. He found that traits are passed from parents to offspring through discrete factors that we now call genes. Mendel's work laid the foundation for modern genetics and showed that inheritance follows specific biological rules.
Genetics is a branch of biology concerned with the study of genes, genetic variation, and heredity in organisms. Though heredity had been observed for millennia, Gregor Mendel, Moravian scientist and Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene.
Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded beyond inheritance to studying the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the context of a population. In science and especially in mathematical studies, a variational principle is one that enables a problem to be solved using calculus of variations, which concerns finding functions that optimize the values of quantities that depend on those functions.
Females have two X chromosomes, while males have one X and one Y chromosome. Females need two X chromosomes because one of the two X chromosomes in each cell of a female is randomly inactivated very early in development. This process, called X-inactivation or lyonization, ensures that females, like males, have only one active X chromosome per cell. It balances gene expression between males and females.
Gregor Mendel conducted experiments with pea plants to establish the basic laws of inheritance. He found that traits from parents separate and recombine in predictable ways when passed to offspring. Mendel determined that traits are determined by discrete factors, now known as genes, which are inherited independently of each other. His work established the fundamental rules of genetics and heredity.
A Visual Guide to 1 Samuel | A Tale of Two HeartsSteve Thomason
These slides walk through the story of 1 Samuel. Samuel is the last judge of Israel. The people reject God and want a king. Saul is anointed as the first king, but he is not a good king. David, the shepherd boy is anointed and Saul is envious of him. David shows honor while Saul continues to self destruct.
THE SACRIFICE HOW PRO-PALESTINE PROTESTS STUDENTS ARE SACRIFICING TO CHANGE T...indexPub
The recent surge in pro-Palestine student activism has prompted significant responses from universities, ranging from negotiations and divestment commitments to increased transparency about investments in companies supporting the war on Gaza. This activism has led to the cessation of student encampments but also highlighted the substantial sacrifices made by students, including academic disruptions and personal risks. The primary drivers of these protests are poor university administration, lack of transparency, and inadequate communication between officials and students. This study examines the profound emotional, psychological, and professional impacts on students engaged in pro-Palestine protests, focusing on Generation Z's (Gen-Z) activism dynamics. This paper explores the significant sacrifices made by these students and even the professors supporting the pro-Palestine movement, with a focus on recent global movements. Through an in-depth analysis of printed and electronic media, the study examines the impacts of these sacrifices on the academic and personal lives of those involved. The paper highlights examples from various universities, demonstrating student activism's long-term and short-term effects, including disciplinary actions, social backlash, and career implications. The researchers also explore the broader implications of student sacrifices. The findings reveal that these sacrifices are driven by a profound commitment to justice and human rights, and are influenced by the increasing availability of information, peer interactions, and personal convictions. The study also discusses the broader implications of this activism, comparing it to historical precedents and assessing its potential to influence policy and public opinion. The emotional and psychological toll on student activists is significant, but their sense of purpose and community support mitigates some of these challenges. However, the researchers call for acknowledging the broader Impact of these sacrifices on the future global movement of FreePalestine.
🔥🔥🔥🔥🔥🔥🔥🔥🔥
إضغ بين إيديكم من أقوى الملازم التي صممتها
ملزمة تشريح الجهاز الهيكلي (نظري 3)
💀💀💀💀💀💀💀💀💀💀
تتميز هذهِ الملزمة بعِدة مُميزات :
1- مُترجمة ترجمة تُناسب جميع المستويات
2- تحتوي على 78 رسم توضيحي لكل كلمة موجودة بالملزمة (لكل كلمة !!!!)
#فهم_ماكو_درخ
3- دقة الكتابة والصور عالية جداً جداً جداً
4- هُنالك بعض المعلومات تم توضيحها بشكل تفصيلي جداً (تُعتبر لدى الطالب أو الطالبة بإنها معلومات مُبهمة ومع ذلك تم توضيح هذهِ المعلومات المُبهمة بشكل تفصيلي جداً
5- الملزمة تشرح نفسها ب نفسها بس تكلك تعال اقراني
6- تحتوي الملزمة في اول سلايد على خارطة تتضمن جميع تفرُعات معلومات الجهاز الهيكلي المذكورة في هذهِ الملزمة
واخيراً هذهِ الملزمة حلالٌ عليكم وإتمنى منكم إن تدعولي بالخير والصحة والعافية فقط
كل التوفيق زملائي وزميلاتي ، زميلكم محمد الذهبي 💊💊
🔥🔥🔥🔥🔥🔥🔥🔥🔥
Elevate Your Nonprofit's Online Presence_ A Guide to Effective SEO Strategies...TechSoup
Whether you're new to SEO or looking to refine your existing strategies, this webinar will provide you with actionable insights and practical tips to elevate your nonprofit's online presence.
CapTechTalks Webinar Slides June 2024 Donovan Wright.pptxCapitolTechU
Slides from a Capitol Technology University webinar held June 20, 2024. The webinar featured Dr. Donovan Wright, presenting on the Department of Defense Digital Transformation.
Temple of Asclepius in Thrace. Excavation resultsKrassimira Luka
The temple and the sanctuary around were dedicated to Asklepios Zmidrenus. This name has been known since 1875 when an inscription dedicated to him was discovered in Rome. The inscription is dated in 227 AD and was left by soldiers originating from the city of Philippopolis (modern Plovdiv).
2. Mendelian Genetics
Gregor Mendel
“Father of Genetics”
Augustinian
Monk at Brno
Monastery in
Austria (now
Czech Republic)
Not a great teacher
but well trained in
math, statistics,
probability,
physics, and
interested in plants
and heredity.
While assigned to
teach, he was also
assigned to tend
the gardens and
grow vegetables
for the monks to
eat.
Mountains with
short, cool growing
season meant pea
(Pisum sativum)
was an ideal crop
plant.
3. Contributions in 1860s (US Civil War Era)
• Discovered Genes as Particles of Inheritance
• Discovered Patterns of Inheritance
• Discovered Genes Come from Both Parents
Egg + Sperm = Zygote
Nature vs Nurture
Sperm means Seed (Homunculus)
• Discovered One Form of Gene (Allele) Dominant
to Another
• Discovered Recessive Allele Expressed in
Absence of Dominant Allele
http://academic.evergreen.edu/v/vivianoc/homunculus.gif
4. Mendel worked with peas (Pisum sativum)
• Good choice for environment of monastery
• Network provided unusual varieties for testing
• Obligate self-pollination reproductive system
Permits side-by-side genetic barriers
Cross-pollinations require intentional process
• Crosses meticulously documented
• Crosses numerically/statistically analyzed
• Scientists of 1860s could not understand math
• Work lost in journals for 50 years!
• Rediscovered in 1900s independently by 3 scientists
• Recognized as landmark work!
5.
6. • Pea plants have several advantages for genetics.
– Pea plants are available in many varieties with distinct
heritable features (characters) with different variants (traits).
– Another advantage of peas is that Mendel had strict control
over which plants mated with which.
– Each pea plant has male
(stamens) and female
(carpal) sexual organs.
– In nature, pea plants typically
self-fertilize, fertilizing ova
with their own sperm.
– However, Mendel could also
move pollen from one plant
to another to cross-pollinate
plants.
7. • In a typical breeding experiment, Mendel
would cross-pollinate (hybridize) two
contrasting, true-breeding pea varieties.
– The true-breeding parents are the P generation and
their hybrid offspring are the F1 generation.
• Mendel would then allow the F1 hybrids to self-
pollinate to produce an F2 generation.
• It was mainly Mendel’s quantitative analysis of
F2 plants that revealed the two fundamental
principles of heredity: the law of segregation
and the law of independent assortment.
8. • If the blending model were correct, the F1 hybrids
from a cross between purple-flowered and white-
flowered pea plants would have pale purple
flowers.
• Instead, the F1 hybrids
all have purple flowers,
just a purple as the
purple-flowered
parents.
2. By the law of segregation, the
two alleles for a characters are
packaged into separate gametes
Fig. 14.2
11. Vocabulary
• Character –heritable feature
• Trait – each variant for a character
• True-breeding – plants that self-pollinate all
offspring are the same variety
• Monohybrid cross – a cross that tracks the
inheritance of a single character
• P generation – (parental) true-breeding
• F1- (first filial) offspring of P generation
• F2 – (second filial) offspring from F1 cross
12. Vocabulary (continued)
• Allele- alternate version of a gene
• Dominate allele – expressed in the heterozygote
• Recessive allele – not expressed in the heterozygote
• Homozygote – pair of identical alleles for a
character
– Homozygous dominant- BB
– Homozygous recessive - bb
• Heterozygote – two different alleles for a character
(Bb)
• Genotype – genetic makeup
• Phenotype – appearance of an organism
13.
14. Wrinkled
P Round
x
F1
All Round
Phenotype
Yet Another Example of Mendel’s Work
F1 x F1 = F2
F2 3
/4 Round
1
/4 Wrinkled
1. Round is dominant to Wrinkled
2. Use W/w rather than R/r for
symbolic logic: in handwriting
make it legible! Ww
ww WW
Ww
Genotype
Homozygous
Recessive
Homozygous
Dominant
Heterozygous
Wrinkled
ww
Round
Ww
w
Round
Ww
Round
WW
W
w
W
Punnett Square:
possible
gametes
possible gametes
NEVER use W/R or w/r
15. Unknown Round Wrinkled
x
Mendel as a Scientist
ww
Round
Ww
Round
Ww
W
Round
Ww
Round
Ww
W
w
w
possible
gametes
possible gametes
F1 x F1 = F2
F2
Wrinkled
ww
Round
Ww
w
Round
Ww
Round
WW
W
w
W
Punnett Square:
possible
gametes
possible gametes
Test Cross:
If Unknown is WW:
Wrinkled
ww
Wrinkled
ww
w
Round
Ww
Round
Ww
W
w
w
possible
gametes
possible gametes
If Unknown is Ww:
Test Progeny All Round
Test Progeny Half Round
Half Wrinkled
16. Unknown Round Wrinkled
x
Mendel as a Scientist
ww
Round
Ww
Round
Ww
W
Round
Ww
Round
Ww
W
w
w
possible
gametes
possible gametes
Test Cross:
If Unknown is WW:
Wrinkled
ww
Wrinkled
ww
w
Round
Ww
Round
Ww
W
w
w
possible
gametes
possible gametes
If Unknown is Ww:
Actual Results Decision
3 Round 2 Wrinkled Ww
2 Round 3 Wrinkled Ww
1 Round 4 Wrinkled Ww
0 Round 5 Wrinkled Ww
4 Round 1 Wrinkled Ww
5 Round 0 Wrinkled WW
<5% chance unknown is Ww
1
/2 • 1
/2 • 1
/2 • 1
/2 • 1
/2 = 1
/32
It only takes 1 wrinkled to be
sure the unknown is Ww!
Small families do not follow
expected ratios perfectly!
You could be wrong (rarely)!
Rare, but it can happen!
20. Test cross – designed to reveal the
genotype of an organism
21. Mendelian Inheritance and Rules
of Probability
• Rule of Multiplication – the probability
that two events will occur simultaneously is
the product of their individual
probabilities
• Probability that an egg from the F1 (Pp)
will receive p = ½
• Probability that an sperm from the F1 (Pp)
will receive p = ½
• Probability that a of offspring receiving
two recessive alleles during fertilization
½ x ½ = ¼
22. Rule Applies to dihybrid Crosses
• For a dihybrid cross, YyRr x YyRr, what is
the probability of an F2 having the
genotype YYRR?
23. Mendel’s Results and
Conclusions
• Mendel concluded
that:
• 1. Each trait is
controlled by 2 genes
or alleles.
• 2. Some alleles are
dominant, while other
alleles are recessive.
• Important terms:
• Homozygous
• Pure bred
• Heterozygous
• hybrid
• Phenotype
• genotype
24. Mendel’s Conclusions
• 3. Law of Segregation
—During meiosis,
each allele separates in
an orderly manner
from its partner, the
two always go to
different gametes.
• 4. Law of Independent
Assortment—During
Metaphase and Anaphase
I of meiosis, the alleles for
different traits segregate
independently. This
mixes chromosomes from
your father and mother.
25. More on Mendel
• Mutiple alleles—
sometimes more than
2 different alleles exist
for a trait. (ABO
blood type).
• Sometimes several
gene pairs work
together to bring about
a trait.
Polygenetic inheritance (skin
color)
Continous variation
Epistatis—a process whereby
a pair of recessive alleles
at one locus masks the
effect of genes at other
loci.(albinism)
Pleiotropy—The effect of
one can can have many
secondary effects. (cystic
fibrosis)
26. Genetics After Mendel
Red
x
Yellow
All Orange
When these alleles go walking, they both do
some talking (codominance)!
OK, so we cannot use R/r nor Y/y so we pick
a third letter…P for the petal color gene.
Notice: we do NOT mix R/Y or r/y!
PR
PR
PY
PY
PR
PY
F1 x F1 = F2
F2
Yellow
PY
PY
Orange
PR
PY
PY
Orange
PR
PY
Red
PR
PR
PR
PY
PR
Punnett Square:
possible
gametes
possible gametes
P
F1
This F2 will NOT have a 3:1 ratio
of phenotypes.
Instead it shows a 1:2:1 ratio!
The exception here proves the rule.
After 1900 several scientists tried to
replicate Mendel’s crosses using other
species including snapdragon.
27. In addition to this, there are multiple alleles possible:
PR
= red PY
= yellow p = no pigment
The combination of alleles in a diploid determine the flower color:
PR
PR
= red
PR
PY
= orange
PY
PY
= yellow
PR
p = pink
PY
p = cream
pp = white
Human hair color follows a similar pattern:
Alleles: HBn
= brown HBd
= blonde hR
= red hbk
= black
The combinations of these alleles determine the base hair color:
HBn
HBn
= dark brown
HBn
HBd
= sandy brown
HBn
hR
= auburn/reddish
brown
HBn
hbk
= dark brown
HBd
HBd
= blonde
HBd
hR
= strawberry
blonde
HBd
hbk
= blonde
hR
hR
= red
hR
hbk
= red
hbk
hbk
= black
Dominant does NOT mean frequent!
Recessive can
be common!
30. Codominance
• Two alleles affect the phenotype in separate
and distinguishable ways.
• Neither allele can mask the other and both
are expressed in the offspring and not in an
“intermediate” form.
• Example: red flowers that are crossed with
white flowers that yield red and white
flowers.
31. Codominance. Human
Blood Types
Codominance is a
condition where two
non-identical alleles
of a pair specify two
different phenotypes,
yet one cannot mask
the expression of the
other (blood types in
humans)
Blood types in
humans are an
example of a multiple
allele system
32. • 1) In cattle, roan coat color (mixed red and white
hairs) occurs in the heterozygous (Rr) offspring of
red (RR) and white (rr) homozygotes. When two
roan cattle are crossed, the phenotypes of the
progeny are found to be in the ratio of 1 red:2
roan:1 white. Which of the following crosses
could produce the highest percentage of roan
cattle?
• A) roan x roan
• B) red x white
• C) white x roan
• D) red x roan
• E) All of the above crosses would give the same
percentage of roan.
33. Pleiotropy
• Most genes have
multiple
phenotypic effects.
The ability of a
gene to affect an
organism in many
ways is called
pleiotropy.
34. Epistasis
Epistasis
• Epistasis occurs
when a gene at one
locus alters or
influences the
expression of a gene
at a second loci. In
this example, C is for
color and the
dominate allele must
be present for
pigment (color) to be
expressed.
35. Phenotype = Genotype + Environment
Crop Yield = Genotype
+ Minerals
+ Water
+ Light
- Pests
etc.
Human Skin Color = Genotype
+ Sun (UV) Exposure
- Aging Factors
The sun exposure effect is most obvious in
people of intermediate skin base color
but everyone can have “tan lines.”
Optimizing these
factors determines
agricultural
productivity…
36. Who Gets To Mate With Whom? …Two Extremes
Inbreeding Depression: related parents give same recessives to children
Hemophilia: Queen Victoria’s Mutation and Diseased Grandchildren
Tay-Sachs: Jewish Populations
Bipolar: Irish Populations
Dog Diseases: German Shepherd hip dysplasia
Hybrid Vigor: recessives of one family are “covered” by dominant of other family
Wild Corn A x Wild Corn B
High Yield Hybrid Corn!
37. Going Outside the Box of a Species: Bread Wheat
AA (diploid wheat) x DD (diploid grass)
AD (sterile diploid)
similar to mule!
AADD
(fertile tetraploid)
Triticum urartu Aegilops tauschii
colchicine
or spontaneous
BB (diploid grass)
BAD (sterile triploid)
colchicine
or spontaneous
BBAADD
Fertile hexaploid
Bread Wheat
Triticum aestivum
Bread Wheat Created 7500 BC with spontaneous doubling of DNA
Levy A. A. and M. Feldman. 2002. The impact of polyploidy on grass genome evolution. Plant Physiol. 130: 1587-1593.
Aegilops speltoides
38. Environmental Impact on Phenotype
pH of the soil will change the color of
hydrangea flowers from blue to pink