This document presents forest plots showing results from primary, secondary, and subgroup analyses comparing the efficacy of two medical interventions. The primary analysis forest plot compares the overall effects of the interventions on the main measured outcomes. Secondary analysis forest plots examine effects on additional secondary outcomes. Subgroup analysis forest plots break down the primary outcomes by patient characteristics to examine treatment effects in specific patient populations.
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Medicina
1. AJ McArdle et al. N Engl J Med 2021;385:11-22.
Forest Plots for Primary, Secondary, and Subgroup Analyses.
Editor's Notes
Figure 2. Forest Plots for Primary, Secondary, and Subgroup Analyses. Shown are outcomes for patients with suspected MIS-C who received IVIG plus glucocorticoids (Panel A) or glucocorticoids alone (Panel B) as compared with those who received IVIG alone (reference group, indicated by an odds ratio or average hazard ratio of 1.00). Odds ratios are shown for all comparisons except time-to-event analyses, for which average hazard ratios were calculated. Values to the right of the dashed vertical line indicate the superiority of IVIG alone, except for the second primary outcome (a reduction in disease severity on the ordinal scale by day 2, indicated by blue arrows), for which values to the left indicate the superiority of IVIG alone.
