This document provides information and formulas for various medical calculations used in pre-hospital settings, including calculations for medication bolus doses, infusion rates, fluid flow rates, and weight-based infusions. It defines common medical abbreviations and covers metric conversions and basic arithmetic. Formulas are provided for intravenous bolus medications, intravenous infusions, weight-based infusions, and intravenous fluid flow rates. Additional "street rules" shortcuts are described for calculating dopamine and lidocaine infusion rates.

1. 1
Medical Mathematics
By Michael Austin, AS, EMT-P, FP-C
There are a few drug calculations necessary in the pre-hospital setting. These calculations are needed to administer IV Bolus medications, IV medication infusions, IV fluid flow rates, and IM/SC injections. In addition, there are a few ‘street rules’ that come in handy. This packet will cover the above listed formulas. In addition, you will receive instruction in metric conversion and a review of basic arithmetic.
Common abbreviations are used in medication administration for all medical fields. Below is a list of some abbreviations that are found in drug calculations used in the pre-hospital setting:
gram = mass
min = minute
Meter = length
IVP = intravenous push
liter = volume
IVPB = intravenous piggyback
kg = kilogram
mg/kg = milligrams per kilogram
gm = gram
mcg/kg = micrograms per kilogram
mg = milligrams
mg/kg/min = milligrams per kilogram per minute
mcg = micrograms
mcg/kg/min = micrograms per kilogram per minute
L = liter
gtts/mL = drops per milliliter
mL = milliliter
gtts/min = drops per minute
cc = mL
concentration = amount of drug in 1mL of fluid
hr = hour
VOH = volume on hand
ATI = amount to be infused
DOH = drug on hand
DD = desired dose
DS = drip set
Metric Conversion
The metric system is an international decimalized system of measurement that was originally introduced by France in 1799. The main feature of the metric system was the standard set of prefixes in powers of ten. The effect of the prefixes is to multiply or divide the unit by a factor of ten, one hundred or one thousand.
kg (kilograms)
gm (grams)
to go up, divide by 1,000 to go down, multiply by 1,000
mg (milligrams)
mcg (micrograms)
Example 1:
Convert 3 grams to milligrams
Multiply 3 grams by 1,000 (going down from grams to milligrams on the chart) to get 3,000mg

2. 2
Example 2:
Convert 2 grams to micrograms
Multiply 2 grams by 1,000 to get 2,000mg, then multiply 2,000 by 1,000 to get 2,000,000mcg
Example 3:
Convert 400 micrograms to milligrams
Divide 400 micrograms (going up from micrograms to milligrams on the chart) to get 0.400mg
Basic Arithmetic
Addition of Integers: Multiplication of Integers:
Example 1: 48+402+7 Example 1: 367 x 78
Example 2: 7.4+4.84+2 Example 2: 7.45 x 5.6
Subtraction of integers: Division of Integers:
Example 1: 919-356 Example 1: 5720/44
Example 2: 9.29-6.43 Example 2: 12.36/0.24

3. 3
IV Medication Bolus / Volume to be Administered
This formula is used when administering a specific medication as a single event. This medication administration can be done via IV, SC or IM.
When you are given a volume to administer, make sure all of the units of measure are in the same prefix. After converting all the units to the same prefix, use the following formula:
Formula: IV Medication Bolus / Volume To Be Administered
desired dose x volume on hand = volume to be administered
drug on hand
Example 1:
You are ordered to give 20mg of Cardizem slow IVP. Your vial contains 25mg of the drug in 5mL of solution. How much of the medication should you administer?
Calculate volume to be administered using formula:
20mg x 5mL = 20mg x 5mL = 100 = 4 mL
25mg 25mg 25
Example 2:
Administer 1.5 mg/kg of lidocaine IVP to a patient. Your lidocaine is packaged 100mg per 5mL of solution. The patient weighs 160lb. How much of the medication should you administer?
Convert all units to like measurements:
160lb = 72kg (160 divided by 2 – 10% = 160/2 - 10% = 80 – 8 = 72)
Calculate desired dose:
1.5mg x 72kg = 108mg
Calculate volume to be administered using formula:
108mg x 5mL = 108mg x 5mL = 540 = 5.40 mL
100mg 100mg 100

4. 4
Example 3:
Administer 0.8mg of Narcan IVP to a patient. Concentration of Narcan is 0.4mg/mL in 10mL of solution. The patient weighs 160lb. How much of the medication should you administer?
Calculate drug on hand:
0.4mg/mL x 10mL = 4mg
Calculate volume to be administered using formula:
0.8mg x 10mL = 0.8mg x 10mL = 8 = 2 mL
4mg 4mg 4
Medication Infusion Rates
Infusion rates are necessary when delivering a medication during a continuous IV infusion. It is important to convert all units to like measurements.
Formula: Medication Infusion Rate
desired dose x drip set = gtts/min
concentration
or
volume on hand x drip set x desired dose = gtts/min
drug on hand
Example 1:
You are to administer a lidocaine infusion at 4mg/min. You have 4 grams of the drug in 500mL of normal saline. The infusion set is 60 gtts/mL. How many drops per minute will you deliver?
Convert all units to like measurements:
1. 4g x 1,000mg = 4,000mg
Calculate concentration:
2. 4,000mg / 500mL = 8mg/mL

5. 5
Calculate drops per minute using infusion rate formula:
4mg/min x 60gtts/mL = 4mg/min x 60gtts/mL = 240 = 30 gtts/min
8mg/mL 8mg/mL 8
or
Convert all units to like measurements:
1. 4g x 1,000mg =4,000mg
Calculate drops per minute using infusion rate formula:
500mL x 60gtts/mL x 4mg/min = 500mL x 60gtts/mL x 4mg/min = 120,000 = 30 gtts/min
4,000mg 4,000mg 4,000
Example 2:
You are to administer epinephrine at 8mcg/min. You have 2mg of the drug in 250mL of normal saline. The infusion set is 60gtts/mL. What is your infusion rate?
Convert all units to like measurements:
1. 2mg x 1,000mcg = 2,000mcg
Calculate concentration:
2. 2,000mcg / 250mL = 8mcg/mL
Calculate drops per minute using infusion rate formula:
8mcg/min x 60gtts/mL = 8mcg/min x 60gtts/mL = 480 = 60gtts/min
8mcg in 1 mL 8mcg in 1 mL 8
or
Convert all units to like measurements:
1. 2mg x 1,000mcg = 2,000mcg
Calculate drops per minute using infusion rate formula:
250mL x 60gtts/mL x 8mcg/min = 250mL x 60gtts/mL x 8mcg/min = 120,000 = 60gtts/min
2,000mcg 2,000mcg 2,000

6. 6
Weight Based Infusion Rate
Drugs like dopamine are administered in micrograms per kilogram per minute. This formula is used to calculate drug administration over time based on patient’s weight.
Formula: Weight Based Infusion Rate
desired dose x weight (kg) x drip set = gtts/min
concentration
Example 1:
Administer 5mcg/kg/min of dopamine to a patient that weights 180lb using a 60gtts/mL drip set. You have 800mg of dopamine in 500mL of normal saline. What is your drip rate?
Convert units to like measurements:
1. 800mg x 1,000 = 800,000mcg
2. 180lb / 2 – 10% = 81kg
Calculate concentration:
1. 800,000mcg / 500ml = 1,600mcg/ml
Calculate drops per minute using formula:
5mcg/kg/min x 81kg x 60gtts/mL = 5mcg/kg/min x 81kg x 60gtts/mL = 24,300 = 15.1875 = 15gtts/min
1,600mcg/mL 1,600mcg/mL 1,600
Example 2:
Administer 10mcg/kg/min of dopamine to a patient that weights 140lb using a 60gtts/mL drip set. You have 400mg of dopamine in 500mL of normal saline. What is your drip rate?
Convert units to like measurements:
1. 400mg x 1,000 = 400,000mcg
2. 140lb / 2 – 10% = 63kg
Calculate concentration:
1. 400,000mcg / 500ml = 800mcg/ml
Calculate drops per minute using formula:
10mcg/kg x 63kg x 60gtts/mL = 10mcg/kg x 63kg x 60gtts/mL = 37,800 = 47.25 = 47gtts/min
800mcg/mL x 1min 800mcg/mL x 1min 800

7. 7
IV Fluid Flow Rate
When calculating IV flow rates, it’s important to know which type of drip set that we should use. The common drip sets are listed below:
10 gtts/mL = standard (trauma or macro) drip
15 gtts/mL = standard (trauma) drip
20 gtts/mL = standard (trauma) drip
60 gtts/mL = microdrip
Formula: IV Fluid Flow Rate
amount to be infused x drip set = gtts/min
time (in minutes)
Example 1:
You are to give 500mL of normal saline over 2 hours using a 15gtts/mL drip set. Calculate the drip rate.
Convert all units to like measurements:
1. 2 hours = 120 min (60min x2)
500mL x 15gtts/mL = 500mL x 15gtts/mL = 7500 = 62.5 = 60 gtts/min
120 minutes 120 minutes 120
Example 2:
You are to administer 4 grams of Magnesium Sulfate over 25 minutes. You have 4 grams of Magnesium Sulfate in 50 mL of Normal Saline. Using a 10gtts/mL drip set, calculate the drip rate.
50mL x 10gtts/mL = 50mL x 10gtts/mL = 500 = 20gtts/min
25 minutes 25 minutes 25

8. 8
Street Rules
There are a few street rules that can be used for certain drugs in certain concentrations. It is imperative that you use the street rules ONLY when you have the correct concentration on hand and are using a 60gtts/mL (micro) drip set.
Dopamine:
For use when the concentration is 1,600mcg/mL and when using a micro (60gtts/mL) drip set. This can be obtained by having 400mg in 250mL; 800mg in 500mL; or 1600mg in 1,000mL. The calculation using the street rules when having the correct concentration will give you a 5mcg/kg/min dose.
Take the patients weight in pounds, rounded to nearest 10, and drop the last number. Subtract one if the patient weighs less than 200lbs, if more than 200lbs, subtract two. This is the gtts/min that will give you roughly 5mcg/kg/min dose.
Example 1:
Patient weighs 184lbs and you are to administer 10mcg/kg/min of dopamine. You have 800mg of dopamine in 500mL of normal saline using a 60gtts/mL drip set.
Patient’s rounded weight in pounds: 180
Drop the last number: 18
Subtract one (patient’s weight is <200lbs): -1
Dosage of 5mcg/kg/min: 17gtts/min
Dosage of 10mcg/kg/min: 34gtts/min
Example 2:
Patient weighs 218lbs and you are to administer 15mcg/kg/min of dopamine. You have 400mg of dopamine in 250mL of normal saline using a 60gtts/mL drip set.
Patient’s rounded weight in pounds: 220
Drop the last number: 22
Subtract two (patient’s weight is >200lbs): -2
Dosage of 5mcg/kg/min: 20gtts/min
Dosage of 10mcg/kg/min: 40gtts/min
Dosage of 15mcg/kg/min: 60gtts/min
Example 3:
Patient weighs 140lb and you are to administer 10mcg/kg/min of dopamine. You have 400mg of dopamine in 500mL of normal saline using a 60gtts/mL drip set.
Unable to use street rules because the concentration is not 1,600mcg/mL. In this
example, the concentration is 0.8mg/mL = 800mcg/mL.

9. 9
Lidocaine:
For use when the concentration is 4mg/mL and when using a micro (60gtts/mL) drip set. This concentration is most commonly seen by having 2 grams in 500mL. This calculation ‘the clock method’ will give you 1-4mg/min dosage when used properly.
So, with the correct concentration, if you needed to administer 2mg/min of lidocaine, you would set your drip rate to 30gtts/min.
60
15
30
45
gtts/min
1mg/min
2mg/min
3mg/min
4mg/min

10. 10
Single Universal Formula Method
The following formula takes aspects of the previously listed formula’s and places them into one single universal formula. To use this formula, you plug in the appropriate values into the formula and omit any values that you are not using. The value time is only used when it is greater than one minute. The advantage of this formula is that there is only one formula to memorize. The disadvantage of this formula is making sure to plug in only the values that you need in order to come up with the correct answer. Remember, incorrect answers in emergency medicine can kill your patient!
Formula: Single Universal Formula
desired dose x weight (kg) x drip set x volume on hand = gtts/min or mL
drug on hand x time (in min)
Example 1:
You are to administer 50mg of Solu-medrol IVP to your pediatric patient. Your vial contains 125mg of the drug in 2mL of solution. How much of the medication should you administer?
Determine which terms from formula you will use:
DD = 50mg
DOH = 125mg
VOH = 2mL
DD x WT x DS x VOH = 50mg x 2mL = 100 = 0.8mL
DOH x TIME 125mg 125
Example 2:
Administer 0.3 mg/kg of etomidate IVP to a patient. Your etomidate is packaged 40mg per 20mL of solution. The patient weighs 160lb. How much of the medication should you administer?
Determine which terms from the formula you will use:
DD = 0.3mg/kg
WT = 72kg (160lbs divided by 2 – 10% = 160/2 - 10% = 80 – 8 = 72)
DOH = 40mg
VOH = 20mL
DD x WT x DS x VOH = 0.3mg/kg x 72kg x 20mL = 432 = 10.8mL
DOH x TIME 40mg 40

11. 11
Example 3:
You are to administer 6mcg/min of an epinephrine infusion. You have 2mg of epinephrine in 250mL of normal saline. You are using a 60gtts/mL drip set. The patient weighs 230lbs. What is your infusion rate?
Determine which terms from the formula you will use:
desired dose or DD = 6mcg/min
drip set or DS = 60gtts/mL
volume on hand or VOH = 250mL
drug on hand or DOH = 2mg = 2,000mcg
DD x WT x DS x VOH = 3mcg/min x 60gtts/mL x 250mL = 45,000 = 22.5gtts/min
DOH x TIME 2,000mcg 2,000
Example 4:
Administer 10mcg/kg/min of dopamine to a patient that weights 240lb using a 60gtts/mL drip set. You have 800mg of dopamine in 500mL of normal saline. What is your infusion rate?
Determine which terms from the formula you will use:
DD = 10mcg/kg/min
WT = 108kg (240lbs divided by 2 – 10% = 240/2 - 10% = 120 – 12 = 108)
DS = 60gtts/mL
VOH = 500mL
DOH = 800mg = 800,000mcg
DD x WT x DS x VOH = 10mcg/kg/min x 108kg x 60gtts/mL x 500mL = 32,400,000 = 40.5gtts/min
DOH x TIME 800,000mcg 800,000
Example 5:
You are to administer 4 grams of Magnesium Sulfate over 25 minutes. You have 4 grams of Magnesium Sulfate in 50 mL of Normal Saline. Using a 10gtts/mL drip set, calculate the drip rate.
Determine which terms from the formula you will use:
DD = 4grams
DS = 10gtts/mL
VOH = 50mL
DOH = 4grams
TIME = 25min
DD x WT x DS x VOH = 4grams x 10gtts/mL x 50mL = 2,000 = 20gtts/min
DOH x TIME 4grams x 25 min 100

12. 12
Example 6:
You are to give 500mL of normal saline over 2 hours using a 15gtts/mL drip set. Calculate the drip rate.
Determine which terms from the formula you will use:
DS = 15gtts/mL
VOH = 500mL
TIME = 120min
DD x WT x DS x VOH = 15gtts/mL x 500mL = 7,500 = 62.5gtts/min
DOH x TIME 120 min 120