Concepts of dental material/tissue interactions example of tissue interactions to dental materials

1. Material Tissue
Interaction

12. Local effects: are a function
of the ability of substances to be
distributed to these sites, their
concentrations, and exposure
times .
Site: the pulp, peridontium, the
root apex, or buccal mucosa or
tongue.
-inflammation or necrosis

13. Systemic effects: are a
function of the distribution of
substances released from materials.
Enter the body via ingestion and
absorption in the gut, inhaled
vapor, release at the tooth apex, or
absorption through the oral
mucosa.
( simple diffusion or transport via the
lymphatic or blood vessels).

15. Cytotoxicity Tests:
assess cell death caused by a
material by measuring cell
number or growth before
and after exposure to that
material

16. Dentin disk barrier test method:
The material is placed on one
side of the dentin disk.
-Collection fluid (cell culture
medium or saline) is on the other
side of the disk.
Components of the material
may diffuse through the dentin
and the effect of the medium on
cell metabolism can then be
measured

17. to test for skin/mucosa
irritation and systemic toxic
effects but also for the
potential of type IV
sensitization to materials.

24. BPA
Diabetes
Neurotoxic
effects
Reduced
fertility

30. The Role of
Residual Dentin
and Bacteria
The Role of
Materials

38. Induction of
Tertiary Dentin
Formation
The Role of
Materials

40. CaOH2/EDTA
Signaling
molecules(TGF b)
Pulpal stem
cells
2ary Odontoblast & tertiary
dentin

45. Schematic of set-up of antimicrobial photodynamic therapy treatment.
The light source used is (He-Ne) laser. The mirror guides the light beam
through a microscope objective (10 ×) to adjust the beam spot to the
size of the well diameter.

56. Scaffolds for Pulp Regeneration
Natural Synthetic
Collagen Polyethylene glycols
(PEGs
Alginate Self-assembling peptides
Fibrin

60. 1) Reactions of Pulp:
1. Microleakage:
2. Dentin Bonding:
Etching??
or

61. 3. Bonding Agents

62. 4. Etching agents

63. 5. Resin-Based Materials

64. 6. Amalgam and Casting Alloys

65. 7. Glass Ionomers

66. 8. Liners, Varnishes, and Non-resin Cements

70. 9. Bleaching Agents:

71. 10. Fissure sealants

72. 11. Fluorides
pea-size

73. 2) Endodontic materials
1. EDTA

74. 2. Sodium hypochlorite


75. 3. Calcium hydroxide

76. 4. Formocresol

77. 5. Gutta-percha

78. 6. Chlorhexidine

79. 7. Mineral trioxide aggregate

80. 3) Reaction of Other Oral Soft Tissues to
restorative Materials

81. Ni orthodontic wire

82. 

84. 4) Reaction of Bone and Soft Tissues to
Implant materials:

87. Resorb-x® plates & meshes

88. 5) Materials for short-term Application

90. a polypropylene thread that was cut too short

91. latex-based rubber dam.

92. 6) Laser in Dentistry

95. Laser
Less pain
Reduce
bacterial
infections
Preserve
tooth
Minimize
bleeding