An immigrant inventor started the first pedicure footspa company in 1975 in Wisconsin. He partnered with another individual in 1983 to focus on footspa equipment. Together they sold thousands of pedicure spas until 1998 when the company was sold. In 2006, the original inventor and partner founded Continuum Footspas to create innovative pedicure chairs, including their flagship Maestro Pedicure Chair which features luxurious design, various massage technologies, and overall customer comfort and relaxation. Continuum Footspas is a family owned business committed to superior pedicure products.
Esse has been a family-owned business for over fifty years. CSL Group is proud to be the exclusive Esse distributor in the U.S., Canada and Israel.
For more details on our products and services, please feel free to visit us at http://www.cslshoes.com/
Audio cityusa offers cost effective vossen wheels & rims of bespoke quali...audiocityusadotcom
One of the unrivaled names in the aftermarket automotive industry, AudioCityUSA offers a wide selection of Vossen wheels & rims of bespoke quality and stylish designs. Available in various sizes, such as 19/20/22 inches, Vossen Wheels are offered in finishes like Bronze, Gold, Grey, Gunmetal, Silver, and Machined.
Esse has been a family-owned business for over fifty years. CSL Group is proud to be the exclusive Esse distributor in the U.S., Canada and Israel.
For more details on our products and services, please feel free to visit us at http://www.cslshoes.com/
Audio cityusa offers cost effective vossen wheels & rims of bespoke quali...audiocityusadotcom
One of the unrivaled names in the aftermarket automotive industry, AudioCityUSA offers a wide selection of Vossen wheels & rims of bespoke quality and stylish designs. Available in various sizes, such as 19/20/22 inches, Vossen Wheels are offered in finishes like Bronze, Gold, Grey, Gunmetal, Silver, and Machined.
A creative hub where ideas and visions come to life with a staunch belief that the best design is genuine and touches people’s life. Our basic premise is “Think First, Create Next”.
We design creative solutions for business challenges, and compelling communication campaigns which will help the brand connect with its audiences across all media channels.
We have studied market dynamics, human behavior and the interactivity of the two A team of experienced professionals who have worked in multinational advertising agencies and film productions to help provide effective solutions towards brand building.
Whether you’re looking to purchase a spa for your home or if you need one for your business, the best choice is Aquavia Spa. Aquavia Spa is Europe’s largest spa manufacturer. With operations in over 30 countries since 1988, it has a wide range of products. Our catalogue covers every conceivable need as our spas have been designed for home use, commercial establishments and for practice sport. Visit: https://spahuset.no/
(c) https://www.spahuset.no Whether you’re looking to purchase a spa for your home or if you need one for your
business, the best choice is Aquavia Spa.
Aquavia Spa is Europe’s largest spa manufacturer. With operations in over 30
countries since 1988, it has a wide range of products. Our catalogue covers every
conceivable need as our spas have been designed for home use, commercial establishments and for practice sport.
All of our hot tubs are proudly manufactured by our team of experts at our manufacturing plant in the USA! Not just assembled here, but built from the ground up by American workers. With our manufacturing plant located in Northumberland, PA since 1993 , Strong Spas™ has evolved into the second largest spa manufacturer in the world. We are pleased to offer you unsurpassed quality, luxury, and style to fit any lifestyle and any budget, with our expansive and robust line of luxury hot tubs, hot tub parts, and accessories. With our North American freight service, and expansive network of Factory Authorized Local Service Technicians, we are able to sell, ship, and service our hot tubs throughout the United States and Canada
Available with a winding drum or counterbalance drive system, the commercial dumbwaiter is an ideal fit for any restaurant, university, clinic, library, laboritory or office building. Choose from a floor level or counter height for loading accessibility and ease.
http://www.transitionsmobility.com
This was a working presentation aimed at S3 pupils (14yrs) during a PRODUCT DESIGN class. They were working through the design process and it ended with them testing out various types of chairs in terms of ergonomics etc. Feel free to chop and change it...
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
A creative hub where ideas and visions come to life with a staunch belief that the best design is genuine and touches people’s life. Our basic premise is “Think First, Create Next”.
We design creative solutions for business challenges, and compelling communication campaigns which will help the brand connect with its audiences across all media channels.
We have studied market dynamics, human behavior and the interactivity of the two A team of experienced professionals who have worked in multinational advertising agencies and film productions to help provide effective solutions towards brand building.
Whether you’re looking to purchase a spa for your home or if you need one for your business, the best choice is Aquavia Spa. Aquavia Spa is Europe’s largest spa manufacturer. With operations in over 30 countries since 1988, it has a wide range of products. Our catalogue covers every conceivable need as our spas have been designed for home use, commercial establishments and for practice sport. Visit: https://spahuset.no/
(c) https://www.spahuset.no Whether you’re looking to purchase a spa for your home or if you need one for your
business, the best choice is Aquavia Spa.
Aquavia Spa is Europe’s largest spa manufacturer. With operations in over 30
countries since 1988, it has a wide range of products. Our catalogue covers every
conceivable need as our spas have been designed for home use, commercial establishments and for practice sport.
All of our hot tubs are proudly manufactured by our team of experts at our manufacturing plant in the USA! Not just assembled here, but built from the ground up by American workers. With our manufacturing plant located in Northumberland, PA since 1993 , Strong Spas™ has evolved into the second largest spa manufacturer in the world. We are pleased to offer you unsurpassed quality, luxury, and style to fit any lifestyle and any budget, with our expansive and robust line of luxury hot tubs, hot tub parts, and accessories. With our North American freight service, and expansive network of Factory Authorized Local Service Technicians, we are able to sell, ship, and service our hot tubs throughout the United States and Canada
Available with a winding drum or counterbalance drive system, the commercial dumbwaiter is an ideal fit for any restaurant, university, clinic, library, laboritory or office building. Choose from a floor level or counter height for loading accessibility and ease.
http://www.transitionsmobility.com
This was a working presentation aimed at S3 pupils (14yrs) during a PRODUCT DESIGN class. They were working through the design process and it ended with them testing out various types of chairs in terms of ergonomics etc. Feel free to chop and change it...
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Integrating Ayurveda into Parkinson’s Management: A Holistic ApproachAyurveda ForAll
Explore the benefits of combining Ayurveda with conventional Parkinson's treatments. Learn how a holistic approach can manage symptoms, enhance well-being, and balance body energies. Discover the steps to safely integrate Ayurvedic practices into your Parkinson’s care plan, including expert guidance on diet, herbal remedies, and lifestyle modifications.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
2. Company Overview.
How it all Began.
In 1975, John Meyerovich, a Russian immigrant came to the United States. John was
an engineer by trade in Russia. He had an idea for a pedicure footspa and invented
the world’s first footspa. John and his immediate family moved to Wisconsin and
opened two nail salons located in Fox Point and in Elm Grove.
The Elm Grove location relocated to Brookfield and both salons expanded into offering
product lines, skin care and nail services. This growth lead to the creation of European
Touch Company, Inc.
Joe Galati met John Meyerovich in 1983 and cofounded European Touch Ltd II which
was the company responsible for the design, development and sale of whirlpool
pedicure spas. John’s primary responsibility was in the nail care products, while Joe’s
primary responsibility was the footspa equipment.
3. Company Overview.
The Legacy Continues.
From 1985 through 1998, thousands of pedicure spas were manufactured and
sold all over the world. Both European Touch companies were sold to Styling
Technology in June of 1998.
Since 1998, Joe and John have kept their finger on the pulse of the pedicure
industry. They sensed an opportunity to bring something innovative and creative
and founded Continuum Footspas LLC in June of 2006.
Continuum Footspas, a family owned company located in New Berlin,
Wisconsin, is totally different, totally committed to superior design,
quality and service.
Welcome to the highest standards in the pedicure industry.
Welcome to the Continuum Footspas family.
4. The Maestro Pedicure Chair
• The Maestro™ promises an alternative
experience guaranteed to satisfy the most
discriminating clientele. But it’s more than
just a pretty face.
• The curvaceous cherry wood base conceals
a steel frame which easily supports 300
pounds, making The Maestro as strong and
beautiful as the arch itself.
5. The Maestro Pedicure Chair
• Sleek lines and distinctive looks highlight
a pedicure chair that is inviting and
functional.
• Integrated lower lumbar support
together with a color coordinated
headrest ensure total comfort and
relaxation.
6. The Basin and Leg Supports
• Featuring a solid surface material similar to Corian®,
the basin is arguably one of The Maestro’s most prominent
features. It’s extremely durable and stain resistant yet
unmistakably beautiful. The Maestro’s basin also
features a patent pending integrated footrest, removable
foot massage rollers and a built-in spout with overflow protection.
• The Maestro’s dual and independent leg supports pivot
upward to support the entire leg, not just the foot. Feet
are perfectly positioned for massage and
pedicure treatments.
7. Acoustic Resonance Massage Technology
• Clients are relaxed by resonating
pulsars embedded into an
incredibly comfortable and beautifully
upholstered* seat cushion.
• Clients select from specially composed passages or may utilize their own
MP3 player to create a customized acoustic resonance experience. High
quality headphones also are provided.
• Touch keypad is embedded into the armrest allowing the client to
effortlessly adjust the resonance and headphone volume independently.
*Upholstery is available in thirteen colors and features luxurious double-stitching in a
contrasting color.
8. NoPipe™ Jet Technology
A Lasting Sensation.
• The Maestro features NoPipe
Jet Technology that provides a
strong, invigorating massage that’s
truly sensational.
• NoPipe Jet Technology is also whisper
quiet and easy to clean.
9. Technician’s Chair
One Incredible Design Deserves Another.
• Curved cherry veneer seat and back.
• Contoured cushion matches The
Maestro chair cushion.
• Telescoping column height range is
15 1/2quot; to 20”.
• Very comfortable, well-made
and functional.
• Coordinates beautifully with
The Maestro pedicure spa.
10. Accessory Cart
Design, Functionality, Convenience.
An exceptionally attractive portable cart that complements
The Maestro in both look and feel.
• Much more than a cheap plastic
accessory cart.
• A large work surface.
• Removable storage tray.
• Extra large towel bin.
11. The Other Details
At Continuum Everything is Important.
• All wood surfaces are solid cherry veneers stained and protected with a
durable conversion varnish finish.
• The Maestro‘s digital controls are designed with convenience, functionality and
quality in mind. Most operational functions are controlled by the touch
of a button.
• Adjustable, color-coordinated neck/head rest is standard.
• Convenient cup holder/tray is standard.
• Drain pump is standard.
• Every Maestro includes a Pedicure Log Book that makes
documentation easy and convenient.
• ETL certified.
• Designed and manufactured in the USA.
12. The Team at Continuum Footspas
Thanks You for Your Support.
• Please share your comments and suggestions with us.
We want to hear from you!
• Call 877.255.3030 or send an email to: info@continuumfootspas.com.
• Visit our website often as it is updated frequently.
www.salonpedicurespas.com
13. CORPORATE HEADQUARTERS MAILING ADDRESS
2236 S. 162ND Street P.O. Box 363
New Berlin, WI 53151 USA Brookfield, WI 53008
USA
p: 262 754 4900 f: 262 754 4901 tf: 1 877 255 3030
www.salonpedicurespas.com