Liver Transplantation in Chennai, India, RIMC is world’s best liver transplant center performing living donor, split liver transplant and paediatric liver transplant.

1. Liver Transplantation

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• Liver Transplantation also known as orthotopic liver transplantation is a major surgical
procedure which has given a new lease of life to thousands of patients suffering from
serious liver disease.
• Research into the possibility of liver transplantation (LT) started before the 1960s with
the pivotal baseline work of Thomas Starzl in Chicago and Boston, where the initial LT
techniques were researched in dogs.
• Starzl attempted the first human LT in 1963 in Denver, but a successful LT was not
achieved until 1967.
• The first human liver transplant was performed in 1967 at the University of Colorado.
• While initial attempts were unsuccessful, persistent efforts by him and a handful of
surgeons around the world have standardized the operation.
• Now most big centres across the world have a success rate of over 90% for this operation.
Liver Transplantation

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Chronic Liver Disease:
•Here the liver is damaged over a prolonged period by continued and repeated injury.
•The cause of injury could be chronic viral infections such as hepatitis C or hepatitis B infection,
prolonged abuse of alcohol.
• Recently, fatty liver disease is on the rise due to unhealthy dietary habits and sedentary life style.
• Over a period of time, fatty liver disease can lead to inflammation (damage) of the liver and this can
also cause chronic liver disease.
• Long-term diabetes is another cause of chronic liver disease due to fat accumulation in the liver.
•Uncommon causes of chronic liver disease are primary biliary cirrhosis, primary sclerosing
cholangitis, autoimmune liver disease where the own cells damage the liver due to their inability to
recognize the liver as its own.
Who Needs a Liver Transplant?

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•The chronically damaged liver goes through the stages of fibrosis and cirrhosis
during which the liver becomes hard and shrunken.
• This affects the liver function causing jaundice, encephalopathy (confusion,
forgetfulness, slowing of thought process), swelling of the abdomen and feet and
abnormalities in the ability of blood to clot.
• The hardened liver increases the resistance to blood flow through the liver causing
complications, such as blood vomiting, blood in stools and fluid in the abdomen.
• The third serious problem with cirrhosis is the development of liver cancer.
Liver transplantation cures all these problems of cirrhosis by replacing the
damaged liver with a new healthy liver.

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• Not all patients with cirrhosis need transplantation.
• Liver transplantation is only advised when the risk of serious complications and
death is high enough to justify a major operation such as liver transplantation.
• In most instances, a careful history, clinical examination and standard blood tests
can help in estimating the severity of liver disease and the risk of complications.
Severity of Chronic Liver Disease

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Symptoms of end stage liver disease include:
• Accumulation of fluid in the abdomen (Ascites). Infection of this abdominal fluid,
called Spontaneous
• Bacterial Peritonitis, is even more ominous.
• Deteriorating kidney function along with liver function (Hepatorenal Syndrome)
• Vomiting of blood or passage of black stools suggestive of bleeding from the
stomach and intestine.
• Altered consciousness, confusion or slow mentation (Hepatic encephalopathy)
Symptoms Of End Stage Liver Disease

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Scoring system to assess need for Liver Transplantation:
• Child Pugh score (CPT) and the Model for End Stage Liver Disease score (MELD
score).
• As a general rule, patients with MELD score greater than 15 have a survival benefit
with transplantation.
• In addition, presence of liver cancer on a background of cirrhosis is a strong
indication for liver transplantation, provided the tumor stage fits into internationally
recognized criteria.
Scoring System For Liver Transplantation

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• Patients with cirrhosis develop liver tumors. Surgical removal of these tumors is
complicated by the poor liver function.
• In such cases, liver transplantation is the ideal cure as it completely removes the
tumors and also removes the diseased liver, which is the breeding ground for these
tumors.
• However, all patients with liver tumors are not suitable for transplantation and the
liver team, which consists of best liver cirrhosis doctor in Chennai, will carry out a
detailed evaluation before suggesting transplant as an appropriate treatment.
Liver Cancer

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• Some patients with Acute Liver Failure can deteriorate despite aggressive medical
treatment and in these patients, liver transplantation is a true life-saver.
• These patients qualify for urgent liver transplantation in most organ allocation
systems around the world.
• Since the availability of this surgery, survival of patients with acute liver failure has
improved from less than 20% to over 80%.
Acute Liver Failure

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Rela Institute & Medical Centre is one of the best liver transplant hospitals in
Chennai, India.
It has provided new lease of life to individuals in desperate need of liver
transplantation in order to survive.
With the best liver transplant surgeon in Chennai, RIMC’s Liver team provides the
best care possible before, during and after the transplant surgery.
We, perhaps, are the best liver transplant specialist hospital in Chennai that can take
care of patients with acute liver diseases who desperately need transplant to get a new
lease of life.
Call us today, we are here to help you!
+91 9384681770
Why RIMC