Lipids and associated disorders_121206.pptx
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High levels of LDL cholesterol and lipoprotein a in the bloodstream, along with conditions like diabetes and hypothyroidism, can lead to the development of atherosclerosis over time. Atherosclerosis occurs when fat, cholesterol, and other substances build up in the arteries in the form of plaque. This plaque hardens and narrows the arteries, reducing blood flow. If a plaque breaks off a coronary artery, it can cause a heart attack. Blood tests can detect high LDL and lipoprotein a levels, and low HDL, as markers for risk of atherosclerosis and coronary heart disease. Lifestyle changes like exercise, diet, weight control and limiting alcohol/saturated fats can help lower cholesterol and reduce risk.
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This document discusses cardiovascular diseases like heart attacks and strokes. It notes that cardiovascular diseases are the leading cause of death in the US, with high blood pressure, cholesterol, smoking, and other factors increasing risk. It then covers topics like atherosclerosis, the pathophysiology of heart attacks and strokes, symptoms, diagnostic tests, and treatments like angioplasty. Lastly, it discusses blood lipid levels, lipoproteins, recommended levels, and lifestyle modifications like the Therapeutic Lifestyle Changes diet and exercise that can help lower risk.
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This document summarizes several common cardiovascular pathologies including heart disease, hypertension, hyperlipidemia, arteriosclerosis, and peripheral vascular disease. It describes their causes, risk factors, symptoms, and treatment and prevention strategies. Heart disease is one of the leading causes of death and includes conditions like coronary artery disease. Hypertension affects over 50 million Americans and increases the risk of heart disease and stroke. Hyperlipidemia and arteriosclerosis involve the buildup of plaque in the arteries. Peripheral vascular disease occurs when blood flow to the limbs is reduced. Lifestyle changes like exercise, diet, and quitting smoking can help prevent and manage many of these conditions.
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Case study C A D
This document summarizes the case of a 73-year-old male patient admitted to the hospital for coronary artery disease. It provides details on his medical history including diabetes, hypertension, and a history of smoking. It then discusses coronary artery disease including symptoms, risk factors, diagnostic tests, treatment options through lifestyle changes, medications, and surgery. It concludes with a nursing care plan to address ineffective airway clearance related to secretions in the bronchi.
Atherosclerosis
Atherosclerosis is characterized by the buildup of fatty plaques, cholesterol, and cellular waste within the inner lining of arteries. Over time, this buildup narrows the arteries and restricts blood flow. The major risk factors for atherosclerosis include increasing age, male gender, family history, smoking, high blood pressure, diabetes, and high cholesterol. The disease process begins with endothelial injury to blood vessels, which allows cholesterol and immune cells like macrophages to accumulate in the artery wall and form fatty streaks. These can progress to raised atherosclerotic plaques made of cells, connective tissue, and lipids that further restrict blood flow. Advanced plaques can rupture or erode, potentially causing heart attacks or strokes if cl
atherosclerosis.pptx
1) Atherosclerosis is a condition where an artery wall thickens due to a build-up of fatty materials such as cholesterol. It is caused by chronic inflammation and accumulation of macrophages in the arteries.
2) It can restrict blood flow and cause blood clots to form. While often considered a heart problem, it can affect arteries anywhere.
3) Risk factors include high blood pressure, high cholesterol, smoking, and diseases like diabetes. It progresses as fatty deposits called plaques build up in artery walls over many years.
Secondary dyslipidemia
This document discusses secondary dyslipidemia, which is dyslipidemia caused by an underlying medical condition or disease. Some common causes mentioned include type 2 diabetes mellitus, cholestatic liver diseases, nephrotic syndrome, chronic renal failure, hypothyroidism, cigarette smoking, obesity, and certain drugs. The document provides details on how each of these conditions can affect lipid levels and lead to secondary dyslipidemia. It also discusses clinical presentations of dyslipidemia, diagnostic testing, and treatment approaches focused on addressing the underlying cause.
coronaryarterydiseases-210917145218.pdf
The document discusses coronary artery disease, which is caused by a buildup of plaque in the coronary arteries, limiting blood flow to the heart. It identifies major risk factors like smoking, high blood pressure, high cholesterol, and diabetes. Symptoms include chest pain and shortness of breath. Diagnosis involves ECG, cardiac enzymes tests, stress tests, and angiography. Treatment involves lifestyle changes, medications like nitroglycerin and statins, and procedures like angioplasty and bypass surgery to restore blood flow.
Coronary artery diseases.
The document discusses coronary artery disease (CAD), which occurs when the coronary arteries become narrowed or blocked, usually due to atherosclerosis. Atherosclerosis involves the buildup of cholesterol and fatty deposits called plaques inside the arteries. CAD risk factors include smoking, high blood pressure, high cholesterol, diabetes, and more. Symptoms include chest pain or angina. Diagnosis involves tests like ECG, cardiac enzymes tests, stress tests, and angiography. Treatment involves lifestyle changes like quitting smoking, diet, exercise, as well as medications, procedures like angioplasty and bypass surgery, and in severe cases, management of chest pain and risk of decreased cardiac output.
Lipid lowering drugs
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Hypercholesterolemia is defined as high levels of cholesterol in the blood (>200mg/dl) and can be caused by conditions like diabetes, hypothyroidism, obstructive jaundice, and nephrotic syndrome. High cholesterol is associated with atherosclerosis and coronary heart disease due to the deposition of cholesterol in artery walls. Low-density lipoprotein (LDL) cholesterol is considered "bad" as it contributes to atherosclerosis, while high-density lipoprotein (HDL) cholesterol is "good" as it protects against atherosclerosis. Diet and lifestyle factors like consuming polyunsaturated fatty acids, plant sterols, fiber, and avoiding high carbohydrate diets can help lower cholesterol levels, as can
一比一原版(Unimelb毕业证书)墨尔本大学毕业证如何办理
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3:国家专业人才认证中心颁发入库证书
4:这个认证书并且可以归档倒地方
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2、国（境）学习人员提供就业推荐信服务
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atherosclerosis.pptx
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2) It can restrict blood flow and cause blood clots to form. While often considered a heart problem, it can affect arteries anywhere.
3) Risk factors include high blood pressure, high cholesterol, smoking, and diseases like diabetes. It progresses as fatty deposits called plaques build up in artery walls over many years.
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Hypercholesterolemia.pptx
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一比一原版(Unimelb毕业证书)墨尔本大学毕业证如何办理
原版制作【微信:41543339】【(Unimelb毕业证书)墨尔本大学毕业证】【微信:41543339】《成绩单、外壳、雅思、offer、留信学历认证（永久存档/真实可查）》采用学校原版纸张、特殊工艺完全按照原版一比一制作（包括：隐形水印，阴影底纹，钢印LOGO烫金烫银，LOGO烫金烫银复合重叠，文字图案浮雕，激光镭射，紫外荧光，温感，复印防伪）行业标杆！精益求精，诚心合作，真诚制作！多年品质 ,按需精细制作，24小时接单,全套进口原装设备，十五年致力于帮助留学生解决难题，业务范围有加拿大、英国、澳洲、韩国、美国、新加坡，新西兰等学历材料，包您满意。
【我们承诺采用的是学校原版纸张（纸质、底色、纹路），我们拥有全套进口原装设备，特殊工艺都是采用不同进口机器一比一制作，仿真度基本可以达到100%，所有工艺效果都可提前给客户展示，不满意可以根据客户要求进行调整，直到满意为止！】
【业务选择办理准则】
一、工作未确定，回国需先给父母、亲戚朋友看下文凭的情况，办理一份就读学校的毕业证【微信41543339】文凭即可
二、回国进私企、外企、自己做生意的情况，这些单位是不查询毕业证真伪的，而且国内没有渠道去查询国外文凭的真假，也不需要提供真实教育部认证。鉴于此，办理一份毕业证【微信41543339】即可
三、进国企，银行，事业单位，考公务员等等，这些单位是必需要提供真实教育部认证的，办理教育部认证所需资料众多且烦琐，所有材料您都必须提供原件，我们凭借丰富的经验，快捷的绿色通道帮您快速整合材料，让您少走弯路。
留信网认证的作用:
1:该专业认证可证明留学生真实身份
2:同时对留学生所学专业登记给予评定
3:国家专业人才认证中心颁发入库证书
4:这个认证书并且可以归档倒地方
5:凡事获得留信网入网的信息将会逐步更新到个人身份内，将在公安局网内查询个人身份证信息后，同步读取人才网入库信息
6:个人职称评审加20分
7:个人信誉贷款加10分
8:在国家人才网主办的国家网络招聘大会中纳入资料，供国家高端企业选择人才
留信网服务项目：
1、留学生专业人才库服务（留信分析）
2、国（境）学习人员提供就业推荐信服务
3、留学人员区块链存储服务
【关于价格问题（保证一手价格）】
我们所定的价格是非常合理的，而且我们现在做得单子大多数都是代理和回头客户介绍的所以一般现在有新的单子 我给客户的都是第一手的代理价格，因为我想坦诚对待大家 不想跟大家在价格方面浪费时间
对于老客户或者被老客户介绍过来的朋友，我们都会适当给一些优惠。
选择实体注册公司办理，更放心，更安全！我们的承诺：客户在留信官方认证查询网站查询到认证通过结果后付款，不成功不收费！
Population Growth in Bataan: The effects of population growth around rural pl...
A population analysis specific to Bataan.
STATATHON: Unleashing the Power of Statistics in a 48-Hour Knowledge Extravag...
"Join us for STATATHON, a dynamic 2-day event dedicated to exploring statistical knowledge and its real-world applications. From theory to practice, participants engage in intensive learning sessions, workshops, and challenges, fostering a deeper understanding of statistical methodologies and their significance in various fields."
Predictably Improve Your B2B Tech Company's Performance by Leveraging Data
Harness the power of AI-backed reports, benchmarking and data analysis to predict trends and detect anomalies in your marketing efforts.
Peter Caputa, CEO at Databox, reveals how you can discover the strategies and tools to increase your growth rate (and margins!).
From metrics to track to data habits to pick up, enhance your reporting for powerful insights to improve your B2B tech company's marketing.
- - -
This is the webinar recording from the June 2024 HubSpot User Group (HUG) for B2B Technology USA.
Watch the video recording at https://youtu.be/5vjwGfPN9lw
Sign up for future HUG events at https://events.hubspot.com/b2b-technology-usa/
在线办理(英国UCA毕业证书)创意艺术大学毕业证在读证明一模一样
学校原件一模一样【微信：741003700 】《(英国UCA毕业证书)创意艺术大学毕业证》【微信：741003700 】学位证，留信认证（真实可查，永久存档）原件一模一样纸张工艺/offer、雅思、外壳等材料/诚信可靠,可直接看成品样本，帮您解决无法毕业带来的各种难题！外壳，原版制作，诚信可靠，可直接看成品样本。行业标杆！精益求精，诚心合作，真诚制作！多年品质 ,按需精细制作，24小时接单,全套进口原装设备。十五年致力于帮助留学生解决难题，包您满意。
本公司拥有海外各大学样板无数，能完美还原。
1:1完美还原海外各大学毕业材料上的工艺：水印，阴影底纹，钢印LOGO烫金烫银，LOGO烫金烫银复合重叠。文字图案浮雕、激光镭射、紫外荧光、温感、复印防伪等防伪工艺。材料咨询办理、认证咨询办理请加学历顾问Q/微741003700
【主营项目】
一.毕业证【q微741003700】成绩单、使馆认证、教育部认证、雅思托福成绩单、学生卡等！
二.真实使馆公证(即留学回国人员证明,不成功不收费)
三.真实教育部学历学位认证（教育部存档！教育部留服网站永久可查）
四.办理各国各大学文凭(一对一专业服务,可全程监控跟踪进度)
如果您处于以下几种情况：
◇在校期间，因各种原因未能顺利毕业……拿不到官方毕业证【q/微741003700】
◇面对父母的压力，希望尽快拿到；
◇不清楚认证流程以及材料该如何准备；
◇回国时间很长，忘记办理；
◇回国马上就要找工作，办给用人单位看；
◇企事业单位必须要求办理的
◇需要报考公务员、购买免税车、落转户口
◇申请留学生创业基金
留信网认证的作用:
1:该专业认证可证明留学生真实身份
2:同时对留学生所学专业登记给予评定
3:国家专业人才认证中心颁发入库证书
4:这个认证书并且可以归档倒地方
5:凡事获得留信网入网的信息将会逐步更新到个人身份内，将在公安局网内查询个人身份证信息后，同步读取人才网入库信息
6:个人职称评审加20分
7:个人信誉贷款加10分
8:在国家人才网主办的国家网络招聘大会中纳入资料，供国家高端企业选择人才
Global Situational Awareness of A.I. and where its headed
You can see the future first in San Francisco.
Over the past year, the talk of the town has shifted from $10 billion compute clusters to $100 billion clusters to trillion-dollar clusters. Every six months another zero is added to the boardroom plans. Behind the scenes, there’s a fierce scramble to secure every power contract still available for the rest of the decade, every voltage transformer that can possibly be procured. American big business is gearing up to pour trillions of dollars into a long-unseen mobilization of American industrial might. By the end of the decade, American electricity production will have grown tens of percent; from the shale fields of Pennsylvania to the solar farms of Nevada, hundreds of millions of GPUs will hum.
The AGI race has begun. We are building machines that can think and reason. By 2025/26, these machines will outpace college graduates. By the end of the decade, they will be smarter than you or I; we will have superintelligence, in the true sense of the word. Along the way, national security forces not seen in half a century will be un-leashed, and before long, The Project will be on. If we’re lucky, we’ll be in an all-out race with the CCP; if we’re unlucky, an all-out war.
Everyone is now talking about AI, but few have the faintest glimmer of what is about to hit them. Nvidia analysts still think 2024 might be close to the peak. Mainstream pundits are stuck on the wilful blindness of “it’s just predicting the next word”. They see only hype and business-as-usual; at most they entertain another internet-scale technological change.
Before long, the world will wake up. But right now, there are perhaps a few hundred people, most of them in San Francisco and the AI labs, that have situational awareness. Through whatever peculiar forces of fate, I have found myself amongst them. A few years ago, these people were derided as crazy—but they trusted the trendlines, which allowed them to correctly predict the AI advances of the past few years. Whether these people are also right about the next few years remains to be seen. But these are very smart people—the smartest people I have ever met—and they are the ones building this technology. Perhaps they will be an odd footnote in history, or perhaps they will go down in history like Szilard and Oppenheimer and Teller. If they are seeing the future even close to correctly, we are in for a wild ride.
Let me tell you what we see.
University of New South Wales degree offer diploma Transcript
澳洲UNSW毕业证书制作新南威尔士大学假文凭定制Q微168899991做UNSW留信网教留服认证海牙认证改UNSW成绩单GPA做UNSW假学位证假文凭高仿毕业证申请新南威尔士大学University of New South Wales degree offer diploma Transcript
Open Source Contributions to Postgres: The Basics POSETTE 2024
Postgres is the most advanced open-source database in the world and it's supported by a community, not a single company. So how does this work? How does code actually get into Postgres? I recently had a patch submitted and committed and I want to share what I learned in that process. I’ll give you an overview of Postgres versions and how the underlying project codebase functions. I’ll also show you the process for submitting a patch and getting that tested and committed.
Intelligence supported media monitoring in veterinary medicine
Media monitoring in veterinary medicien
一比一原版(GWU,GW文凭证书)乔治·华盛顿大学毕业证如何办理
毕业原版【微信:176555708】【(GWU,GW毕业证书)乔治·华盛顿大学毕业证】【微信:176555708】成绩单、外壳、offer、留信学历认证（永久存档真实可查）采用学校原版纸张、特殊工艺完全按照原版一比一制作（包括：隐形水印，阴影底纹，钢印LOGO烫金烫银，LOGO烫金烫银复合重叠，文字图案浮雕，激光镭射，紫外荧光，温感，复印防伪）行业标杆！精益求精，诚心合作，真诚制作！多年品质 ,按需精细制作，24小时接单,全套进口原装设备，十五年致力于帮助留学生解决难题，业务范围有加拿大、英国、澳洲、韩国、美国、新加坡，新西兰等学历材料，包您满意。
【我们承诺采用的是学校原版纸张（纸质、底色、纹路），我们拥有全套进口原装设备，特殊工艺都是采用不同机器制作，仿真度基本可以达到100%，所有工艺效果都可提前给客户展示，不满意可以根据客户要求进行调整，直到满意为止！】
【业务选择办理准则】
一、工作未确定，回国需先给父母、亲戚朋友看下文凭的情况，办理一份就读学校的毕业证【微信176555708】文凭即可
二、回国进私企、外企、自己做生意的情况，这些单位是不查询毕业证真伪的，而且国内没有渠道去查询国外文凭的真假，也不需要提供真实教育部认证。鉴于此，办理一份毕业证【微信176555708】即可
三、进国企，银行，事业单位，考公务员等等，这些单位是必需要提供真实教育部认证的，办理教育部认证所需资料众多且烦琐，所有材料您都必须提供原件，我们凭借丰富的经验，快捷的绿色通道帮您快速整合材料，让您少走弯路。
留信网认证的作用:
1:该专业认证可证明留学生真实身份
2:同时对留学生所学专业登记给予评定
3:国家专业人才认证中心颁发入库证书
4:这个认证书并且可以归档倒地方
5:凡事获得留信网入网的信息将会逐步更新到个人身份内，将在公安局网内查询个人身份证信息后，同步读取人才网入库信息
6:个人职称评审加20分
7:个人信誉贷款加10分
8:在国家人才网主办的国家网络招聘大会中纳入资料，供国家高端企业选择人才
留信网服务项目：
1、留学生专业人才库服务（留信分析）
2、国（境）学习人员提供就业推荐信服务
3、留学人员区块链存储服务
→ 【关于价格问题（保证一手价格）】
我们所定的价格是非常合理的，而且我们现在做得单子大多数都是代理和回头客户介绍的所以一般现在有新的单子 我给客户的都是第一手的代理价格，因为我想坦诚对待大家 不想跟大家在价格方面浪费时间
对于老客户或者被老客户介绍过来的朋友，我们都会适当给一些优惠。
选择实体注册公司办理，更放心，更安全！我们的承诺：客户在留信官方认证查询网站查询到认证通过结果后付款，不成功不收费！
一比一原版(UO毕业证)渥太华大学毕业证如何办理
UO毕业证录取书【微信95270640】购买（渥太华大学毕业证成绩单硕士学历）Q微信95270640代办UO学历认证留信网伪造渥太华大学学位证书精仿渥太华大学本科/硕士文凭证书补办渥太华大学 diplomaoffer,Transcript购买渥太华大学毕业证成绩单购买UO假毕业证学位证书购买伪造渥太华大学文凭证书学位证书,专业办理雅思、托福成绩单，学生ID卡，在读证明，海外各大学offer录取通知书，毕业证书，成绩单，文凭等材料:1:1完美还原毕业证、offer录取通知书、学生卡等各种在读或毕业材料的防伪工艺（包括 烫金、烫银、钢印、底纹、凹凸版、水印、防伪光标、热敏防伪、文字图案浮雕，激光镭射，紫外荧光，温感光标）学校原版上有的工艺我们一样不会少，不论是老版本还是最新版本，都能保证最高程度还原，力争完美以求让所有同学都能享受到完美的品质服务。
文凭办理流程：
1客户提供办理信息：姓名生日专业学位毕业时间等（如信息不确定可以咨询顾问：微信95270640我们有专业老师帮你查询）；
2开始安排制作毕业证成绩单电子图；
3毕业证成绩单电子版做好以后发送给您确认；
4毕业证成绩单电子版您确认信息无误之后安排制作成品；
5成品做好拍照或者视频给您确认；
6快递给客户（国内顺丰国外DHLUPS等快读邮寄）。
7完成交易删除客户资料
高精端提供以下服务：
一：渥太华大学渥太华大学毕业证文凭证书全套材料从防伪到印刷水印底纹到钢印烫金
二：真实使馆认证（留学人员回国证明）使馆存档
三：真实教育部认证教育部存档教育部留服网站可查
四：留信认证留学生信息网站可查
五：与学校颁发的相关证件1:1纸质尺寸制定（定期向各大院校毕业生购买最新版本毕,业证成绩单保证您拿到的是鲁昂大学内部最新版本毕业证成绩单微信95270640）
A.为什么留学生需要操作留信认证?
留信认证全称全国留学生信息服务网认证,隶属于北京中科院。①留信认证门槛条件更低,费用更美丽,并且包过,完单周期短,效率高②留信认证虽然不能去国企,但是一般的公司都没有问题,因为国内很多公司连基本的留学生学历认证都不了解。这对于留学生来说,这就比自己光拿一个证书更有说服力,因为留学学历可以在留信网站上进行查询!
B.为什么我们提供的毕业证成绩单具有使用价值？
查询留服认证是国内鉴别留学生海外学历的唯一途径但认证只是个体行为不是所有留学生都操作所以没有办理认证的留学生的学历在国内也是查询不到的他们也仅仅只有一张文凭。所以这时候我们提供的和学校颁发的一模一样的毕业证成绩单就有了使用价值。只硕大的蛇皮袋手里拎着长铁钩正站在门口朝黑色的屋内张望不好坏人小偷山娃一怔却也灵机一动立马仰起头双手拢在嘴边朝楼上大喊：“爸爸爸——有人找——那人一听朝山娃尴尬地笑笑悻悻地走了山娃立马“嘭的一声将铁门锁死心却咚咚地乱跳当山娃跟父亲说起这事时父亲很吃惊抚摸着山娃的头说还好醒得及时要不家早被人掏空了到时连电视也没得看啰不过父亲还是夸山娃能临危不乱随机应变有胆有谋山娃笑笑说那都是书上学的看童话和小说时多
The Building Blocks of QuestDB, a Time Series Database
Talk Delivered at Valencia Codes Meetup 2024-06.
Traditionally, databases have treated timestamps just as another data type. However, when performing real-time analytics, timestamps should be first class citizens and we need rich time semantics to get the most out of our data. We also need to deal with ever growing datasets while keeping performant, which is as fun as it sounds.
It is no wonder time-series databases are now more popular than ever before. Join me in this session to learn about the internal architecture and building blocks of QuestDB, an open source time-series database designed for speed. We will also review a history of some of the changes we have gone over the past two years to deal with late and unordered data, non-blocking writes, read-replicas, or faster batch ingestion.
The Ipsos - AI - Monitor 2024 Report.pdf
According to Ipsos AI Monitor's 2024 report, 65% Indians said that products and services using AI have profoundly changed their daily life in the past 3-5 years.
Learn SQL from basic queries to Advance queries
Dive into the world of data analysis with our comprehensive guide on mastering SQL! This presentation offers a practical approach to learning SQL, focusing on real-world applications and hands-on practice. Whether you're a beginner or looking to sharpen your skills, this guide provides the tools you need to extract, analyze, and interpret data effectively.
Key Highlights:
Foundations of SQL: Understand the basics of SQL, including data retrieval, filtering, and aggregation.
Advanced Queries: Learn to craft complex queries to uncover deep insights from your data.
Data Trends and Patterns: Discover how to identify and interpret trends and patterns in your datasets.
Practical Examples: Follow step-by-step examples to apply SQL techniques in real-world scenarios.
Actionable Insights: Gain the skills to derive actionable insights that drive informed decision-making.
Join us on this journey to enhance your data analysis capabilities and unlock the full potential of SQL. Perfect for data enthusiasts, analysts, and anyone eager to harness the power of data!
#DataAnalysis #SQL #LearningSQL #DataInsights #DataScience #Analytics
Beyond the Basics of A/B Tests: Highly Innovative Experimentation Tactics You...
This webinar will explore cutting-edge, less familiar but powerful experimentation methodologies which address well-known limitations of standard A/B Testing. Designed for data and product leaders, this session aims to inspire the embrace of innovative approaches and provide insights into the frontiers of experimentation!
原版制作(unimelb毕业证书)墨尔本大学毕业证Offer一模一样
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Lipids and associated disorders_121206.pptx
- 23. Atherosclerosis • Atherosclerosis is a complex disease characterized by thickening or hardening of arteries due to the accumulation of lipids (particularly cholesterol, free, and esterified) collagen, fibrous tissue, proteoglycans, calcium deposits etc. in the inner arterial wall resulting in formation of plaque that narrows and ultimately blocks the arteries causing the stoppage of blood flow resulting in the death of affected tissue. Coronary arteries— the arteries supplying blood to heart—are the most commonly affected leading to myocardial infarction or heart attacks.
- 27. Causes of atherosclerosis High LDL: The development of atherosclerosis and the risk for the coronary heart disease (CHD) is directly correlated with plasma cholesterol and LDL. On the other hand, plasma HDL is inversely correlated with CHD. The increased levels of plasma HDL (good cholesterol) are correlated with a low incidence of cardiovascular disorders. Lipoprotein a : Lipoprotein a (Lp-a) is almost identical in structure to LDL. Lp-a contains an additional apoprotein, apo-a. Lp-a inhibits fibrinolysis. The elevation of lipoprotein-a in the plasma (>30 mg/dl) suggests increased risk of CHD. It is hypothesized that elevated Lp-a reduces the breakdown of blood clots by interfering with plasminogen activation. This results in intravascular thrombosis, and increased risk of heart attacks. . Disorders that may cause atherosclerosis: Certain diseases are associated with atherosclerosis. These include diabetes mellitus, hyperlipoproteinemias, nephrotic syndrome, hypothyroidism etc. Many other factors like obesity, high consumption of saturated fat, excessive smoking, lack of physical exercise, hypertension, stress etc., are the probable causes of atherosclerosis.
- 28. Diagnosis Blood tests: blood tests usually show • High LDL • Low HDL • High total cholestrol • High Lipoprotein a(Lp-a)
- 30. Treatment Can be reduced by dietery changes and life style modifications such as • Strenuous physical exercise • Moderate alcohol intake, • Consumption of unsaturated fatty acids (vegetable and fish oils), • Reduction in body weight —all tend to increase HDL levels and reduce the risk CHD