Laminar fMRI with Rosette space trajectory
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PETALUTE modified rosette for Sodium MRI
In this work, we demonstrate the sodium magnetic resonance imaging (MRI) capabilities of a three-dimensional (3D) dual-echo ultrashort echo time (UTE) sequence with a novel rosette petal trajectory (PETALUTE), in comparison to the 3D density-adapted (DA) radial spokes UTE sequence. #mri #ismrm #msk
PETALUTE: Preclinical Applications of the Modified Rosette for FAST-Flexible ...
PETALUTE: Preclinical Applications of the Modified Rosette for FAST-Flexible Contrast MR(S)I
3D UTE 31P-MRSI with modified rosette k-space (PETALUTE): Comparison with con...
Phosphorus-31 magnetic resonance spectroscopic imaging (31P-MRSI) provides valuable non-invasive in vivo information on tissue metabolism but is burdened by poor sensitivity and prolonged scan duration. Ultra-short echo time (UTE) acquisitions minimize signal loss when probing signals with relatively short spin-spin relaxation time (T2), while also preventing first-order dephasing. Here, a three-dimensional (3D) UTE sequence with a rosette k-space trajectory is applied to 31P-MRSI at 3T. Conventional chemical shift imaging (CSI) employs highly regular Cartesian k-space sampling, susceptible to substantial artifacts when accelerated via undersampling. In contrast, this novel sequence’s “petal-like” pattern offers incoherent sampling more suitable for compressed sensing (CS). These results showcase the competitive performance of UTE rosette 31P-MRSI against conventional weighted CSI with simulation, phantom, and in vivo leg muscle comparisons.
Modified Rosette PETALUTE for preclinical imaging
We have demonstrated a sequence, PETALUTE, for clinical and preclinical high (3T) and ultra-high fields (>7T) scanners.
The modified Rosette kspace dual-echo Acquisition/ PETALUTE strategy could further enhance integrated and translational research studies to understand human and non-human complex structures and physiologies better.
Lung imaging Using 3D Dual-Echo FID Ultra-short Echo Time MRI with novel Rose...
Lung imaging Using 3D Dual-Echo FID Ultra-short Echo Time MRI with novel Rosette k-space Pattern: PETALUTE
Multisite UTE 31P Rosette MRSI(PETALUTE)
While Phosphorous (31P) MRS (I) has been promising in experimental and clinical settings since the early 70s, it has been beset by prohibitively lower sensitivity, limited spectral-spatial resolution, and prolonged acquisition. This manuscript and proceedings of the annual scientific meeting of ISMRM in 2022 (REF1) and 2023 (REF2) demonstrate that our novel acquisition strategy, the novel Rosette Trajectory for fast and flexible MR(S)I contrast (Shen et al. 2023 (REF3), later we renamed it as PETALUTE after the translation to the preclinical scanners of 7T and 9.4T), enables operator-independent (1) rapid acquisition (~7 minutes), (2) reconstruction, and (3) processing pipeline, resulting in phosphorous metabolite ratio maps (10 x 10 x 10 mm3) of the whole brain.
In response to the “Repeat it with Me” challenge organized by the Reproducible Research study group of ISMRM, we demonstrated the power of this technique in 5 healthy volunteers at three different institutions with different experimental setups (2nd Place: UTE 31P 3D Rosette MRSI Reproducibility Team, REF4). Since the proposed acquisition/reconstruction/processing pipeline was operator/scanner/coil-independent, the Reproducer sub-teams successfully replicated the findings of the original proceeding in 2022 (REF1). As part of this challenge, we provided some MATLAB scripts and k-space data to reproduce some of the results described in this manuscript. The software and data can be downloaded from https://purr.purdue.edu/projects/ismrm31pmrsi.
These results will likely be of broad interest across clinical settings since the proposed acquisition strategy is not specific to any region, nuclei, or magnetic field and is operator-independent. This study's resolution and signal-to-noise ratios permit the metabolite maps in an experimentally and clinically feasible timeframe at 3 Tesla and 7T.
REF1 Bozymski B, Shen X, Ozen AC, Ibey S, Chiew M, Thomas A, Dydak U, Emir UE. Ultra-Short Echo Time 31P 3D MRSI at 3T with Novel Rosette k-space Trajectory. Proceedings 30th Scientific Meeting, International Society for Magnetic Resonance in Medicine, 2022.
REF2 Farley N, Bozymski B, Dydak U, Emir UE*. Fast 3D 31P MRSI Using Novel Rosette Petal Trajectory at 3T with x4 Accelerated Compressed Sensing. Proceedings 31st Scientific Meeting, International Society for Magnetic Resonance in Medicine, 2023.
REF3 Shen X, Özen AC, Sunjar A, Ilbey S, Sawiak S, Shi R, Chiew M, Emir UE. Ultrashort T2 components imaging of the whole brain using 3D dual-echo UTE MRI with rosette k-space pattern. Magnetic Resonance in Medicine. 2023;89(2):508–521.
REF4 https://challenge.ismrm.org/2023-24-reproducibility-challenge/results-22-23/
Rosette Applications (MRI and MRSI) at UHF human (7T) and animal scanners (9....
MRI
MRSI
LEAF
PETAL
EGG
ROSETTE
MRI
siemens
bruker
his study aimed to develop a new 3D dual-echo rosette k-space trajectory, specifically for applications of ultra-short echo time (UTE) magnetic resonance imaging (MRI). The direct imaging of the myelin bilayer, which has ultra-short transverse relaxation time (uT2), was acquired to test the performance of the proposed UTE sequence.
Theory and Methods The rosette trajectory was developed based on rotations of a ‘petal-like’ pattern in the kx-ky plane, with oscillated extensions in kz-direction for 3D coverage. Five healthy volunteers were recruited and underwent ten dual-echo rosette UTE scans with varied echo times (TEs). Dual-exponential model fitting was performed to separate uT2 signals, with the output of uT2 fraction, uT2 value and long T2 value.
Results The reconstructed images’ signal contrast between white matter (WM) and grey matter (GM) increased with longer TEs. The WM regions had higher uT2 fraction values than GM (10.9%±1.9% vs. 5.7%±2.4%). The uT2 value was about 0.12 milliseconds in WM.
Conclusion The higher uT2 fraction value in WM compared to GM demonstrated the ability of the proposed sequence to capture rapidly decaying signals.
Submillimeter fMRI Acquisition using a dual-echo Rosette kspace trajectory at 3T
Submillimeter fMRI Acquisition using a dual-echo Rosette kspace trajectory at 3T
Recommended
PETALUTE modified rosette for Sodium MRI
In this work, we demonstrate the sodium magnetic resonance imaging (MRI) capabilities of a three-dimensional (3D) dual-echo ultrashort echo time (UTE) sequence with a novel rosette petal trajectory (PETALUTE), in comparison to the 3D density-adapted (DA) radial spokes UTE sequence. #mri #ismrm #msk
PETALUTE: Preclinical Applications of the Modified Rosette for FAST-Flexible ...
PETALUTE: Preclinical Applications of the Modified Rosette for FAST-Flexible Contrast MR(S)I
3D UTE 31P-MRSI with modified rosette k-space (PETALUTE): Comparison with con...
Phosphorus-31 magnetic resonance spectroscopic imaging (31P-MRSI) provides valuable non-invasive in vivo information on tissue metabolism but is burdened by poor sensitivity and prolonged scan duration. Ultra-short echo time (UTE) acquisitions minimize signal loss when probing signals with relatively short spin-spin relaxation time (T2), while also preventing first-order dephasing. Here, a three-dimensional (3D) UTE sequence with a rosette k-space trajectory is applied to 31P-MRSI at 3T. Conventional chemical shift imaging (CSI) employs highly regular Cartesian k-space sampling, susceptible to substantial artifacts when accelerated via undersampling. In contrast, this novel sequence’s “petal-like” pattern offers incoherent sampling more suitable for compressed sensing (CS). These results showcase the competitive performance of UTE rosette 31P-MRSI against conventional weighted CSI with simulation, phantom, and in vivo leg muscle comparisons.
Modified Rosette PETALUTE for preclinical imaging
We have demonstrated a sequence, PETALUTE, for clinical and preclinical high (3T) and ultra-high fields (>7T) scanners.
The modified Rosette kspace dual-echo Acquisition/ PETALUTE strategy could further enhance integrated and translational research studies to understand human and non-human complex structures and physiologies better.
Lung imaging Using 3D Dual-Echo FID Ultra-short Echo Time MRI with novel Rose...
Lung imaging Using 3D Dual-Echo FID Ultra-short Echo Time MRI with novel Rosette k-space Pattern: PETALUTE
Multisite UTE 31P Rosette MRSI(PETALUTE)
While Phosphorous (31P) MRS (I) has been promising in experimental and clinical settings since the early 70s, it has been beset by prohibitively lower sensitivity, limited spectral-spatial resolution, and prolonged acquisition. This manuscript and proceedings of the annual scientific meeting of ISMRM in 2022 (REF1) and 2023 (REF2) demonstrate that our novel acquisition strategy, the novel Rosette Trajectory for fast and flexible MR(S)I contrast (Shen et al. 2023 (REF3), later we renamed it as PETALUTE after the translation to the preclinical scanners of 7T and 9.4T), enables operator-independent (1) rapid acquisition (~7 minutes), (2) reconstruction, and (3) processing pipeline, resulting in phosphorous metabolite ratio maps (10 x 10 x 10 mm3) of the whole brain.
In response to the “Repeat it with Me” challenge organized by the Reproducible Research study group of ISMRM, we demonstrated the power of this technique in 5 healthy volunteers at three different institutions with different experimental setups (2nd Place: UTE 31P 3D Rosette MRSI Reproducibility Team, REF4). Since the proposed acquisition/reconstruction/processing pipeline was operator/scanner/coil-independent, the Reproducer sub-teams successfully replicated the findings of the original proceeding in 2022 (REF1). As part of this challenge, we provided some MATLAB scripts and k-space data to reproduce some of the results described in this manuscript. The software and data can be downloaded from https://purr.purdue.edu/projects/ismrm31pmrsi.
These results will likely be of broad interest across clinical settings since the proposed acquisition strategy is not specific to any region, nuclei, or magnetic field and is operator-independent. This study's resolution and signal-to-noise ratios permit the metabolite maps in an experimentally and clinically feasible timeframe at 3 Tesla and 7T.
REF1 Bozymski B, Shen X, Ozen AC, Ibey S, Chiew M, Thomas A, Dydak U, Emir UE. Ultra-Short Echo Time 31P 3D MRSI at 3T with Novel Rosette k-space Trajectory. Proceedings 30th Scientific Meeting, International Society for Magnetic Resonance in Medicine, 2022.
REF2 Farley N, Bozymski B, Dydak U, Emir UE*. Fast 3D 31P MRSI Using Novel Rosette Petal Trajectory at 3T with x4 Accelerated Compressed Sensing. Proceedings 31st Scientific Meeting, International Society for Magnetic Resonance in Medicine, 2023.
REF3 Shen X, Özen AC, Sunjar A, Ilbey S, Sawiak S, Shi R, Chiew M, Emir UE. Ultrashort T2 components imaging of the whole brain using 3D dual-echo UTE MRI with rosette k-space pattern. Magnetic Resonance in Medicine. 2023;89(2):508–521.
REF4 https://challenge.ismrm.org/2023-24-reproducibility-challenge/results-22-23/
Rosette Applications (MRI and MRSI) at UHF human (7T) and animal scanners (9....
MRI
MRSI
LEAF
PETAL
EGG
ROSETTE
MRI
siemens
bruker
his study aimed to develop a new 3D dual-echo rosette k-space trajectory, specifically for applications of ultra-short echo time (UTE) magnetic resonance imaging (MRI). The direct imaging of the myelin bilayer, which has ultra-short transverse relaxation time (uT2), was acquired to test the performance of the proposed UTE sequence.
Theory and Methods The rosette trajectory was developed based on rotations of a ‘petal-like’ pattern in the kx-ky plane, with oscillated extensions in kz-direction for 3D coverage. Five healthy volunteers were recruited and underwent ten dual-echo rosette UTE scans with varied echo times (TEs). Dual-exponential model fitting was performed to separate uT2 signals, with the output of uT2 fraction, uT2 value and long T2 value.
Results The reconstructed images’ signal contrast between white matter (WM) and grey matter (GM) increased with longer TEs. The WM regions had higher uT2 fraction values than GM (10.9%±1.9% vs. 5.7%±2.4%). The uT2 value was about 0.12 milliseconds in WM.
Conclusion The higher uT2 fraction value in WM compared to GM demonstrated the ability of the proposed sequence to capture rapidly decaying signals.
Submillimeter fMRI Acquisition using a dual-echo Rosette kspace trajectory at 3T
Submillimeter fMRI Acquisition using a dual-echo Rosette kspace trajectory at 3T
Fast 3D-P31-MRSI Using Custom Rosette Petal Trajectory at 3T with 4x Accelera...
Fast 3D-P31-MRSI Using Custom Rosette Petal Trajectory at 3T with 4x Accelerated Compressed Sensing
Ultra-Short Echo Time 31P 3D MRSI at 3T/7T with Novel Rosette k-space Trajectory
ltra-Short Echo Time 31P 3D MRSI at 3T/7T with Novel Rosette k-space Trajectory
Submillimeter fMRI Acquisition using a dual-echo Rosette kspace trajectory
Submillimeter fMRI Acquisition using a dual-echo Rosette kspace trajectory
Ultra-Short Echo Time 31P 3D MRSI at 3T with Novel Rosette k-space Trajectory
Ultra-Short Echo Time 31P 3D MRSI at 3T with Novel Rosette k-space Trajectory
UTE 31P 3D Rosette MRSI reproducibility
UTE 31P 3D Rosette MRSI reproducibility Team has demonstrated the Reproducibility of the method. The method has been challenged on #siemenshealthineers PET-MRI (mMR) and Prisma 3T scanners.ISMRM #spectroscopy ISMRM ChallengeISMRM RAPID Biomedical
https://lnkd.in/gnjCHtu2
Submillimeter fMRI Acquisition using a dual-echo Rosette kspace trajectory at 3T
n this study, we overcome the technological barrier against acquiring submillimeter resolution (~ 0.5 mm) fMRI data at 3T via a novel dual-echo Rosette k-space design. This design results in the fine representation of activation maps in two different functional tasks and might be a springboard in neuroimaging by providing very high-resolution spatiotemporal dynamics of neural networks. The method will be further evolved with the feedback from the MRI community via the GitHub platform as such for further acceleration, inflow saturation, and 3D coverage via 3D sampling and/or multiband approaches.
rosette fmri very high resolution at 3T
rosette fmri very high resolution at 3T
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3D-UTE Rosette MRI and MRSI at UHF human (7T) and animal scanners (9.4T) usin...
#ismrm #ISMRM2022 #ISMRM22
3D-UTE Rosette Applications (MRI and MRSI) at UHF human (7T) and animal scanners (9.4T) using The Berkeley Advanced Reconstruction Toolbox (BART) toolbox
Uzay Emir
Afternoon Tea with BART
Time: 15:45-16:45
Simultaneous Measurement of functional MRI and MRS by Fast Non-water Suppress...
The non-water suppressed magnetic resonance spectroscopic imaging (MRSI) sequence with concentric k-space trajectory was proposed to measure functional MRI and MRSI signals simultaneously. A right-hand finger-tapping task was performed at 3T MRI scanner to test the simultaneous hemodynamic and neurochemical measurements in the human primary motor cortex. The results showed a significant overlap betweenT2* and metabolite (glutamate) changes.
Quantitative Susceptibility Mapping (QSM) Using High-resolution Ultra-Short E...
Karnik A, Shen X, Monsivais H, Sunjar A, Özen A, Ilbey S, Chiew M, Cakmak M, Rispoli J, Emir UE., Quantitative Susceptibility Mapping (QSM) Using High-resolution Ultra-Short Echo Time (UTE) MRI with Rosette k-space Pattern International Society for Magnetic Resonance in Medicine Annual Meeting 2022
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1H/31P 3D MRSI at 3T with Novel Rosette k-space Trajectory with compressed se...
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Bozymski B, Shen X, Özen A, Ilbey S, Thomas MA, Chiew M, Dydak U, Emir UE. Ultra-Short Echo Time 31P 3D MRSI at 3T with Novel Rosette k-space Trajectory, International Society for Magnetic Resonance in Medicine Annual Meeting 2022
CMRR workshop in vivo GABA Glutamate and fMRI BOLD imaging Event-Related fMRS
CMRR workshop
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GABA Glutamate UHF Semi-laser
Advanced Magnetic Resonance Spectroscopy Protocol at 7T
7T hardware (Siemens Scanner and Nova Medical head coil), BaTiO3 dielectric padding
Ip et al., 2017 NeuroImage
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Time-Resolved fMRI-fMRS measures simultaneous Neurotransmitters and BOLD-fMRI...
Time-Resolved fMRI-fMRS measures simultaneous Neurotransmitters and BOLD-fMRI signals in the human brain at 7T
2021 Minnesota Workshop on High and Ultra-high Field Imaging
https://bit.ly/3kE66qk
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standardization
Across-vendor
semi-LASER
single-voxel
MRS
3T
GABA spectroscopy
edited GABA 1H MEGA-PRESS spectra
GABA-edited
Magnetic Resonance Spectroscopy, MRI, Human Connectome, 2-HG, 2-hydroxyglutarate, zoom, zoom MRSI, reduced field of View, rFOV, Cerebellum, High-resolution, IDH, Isocitrate, IDH1, IDH2, Cancer, Glioma, Parcellation, Macro Anatomical
Functional
Myeloarchitectonic
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MR Spectroscopy Study Group
fMRI - fMRSI
glutamate
gaba
fMRS
ISMRM
standardization
Across-vendor
semi-LASER
single-voxel
MRS
3T
human brain mapping
GABAergic inhibition in the human visual cortex relates to eye dominance
Binocular vision is created by fusing the separate inputs arriving from left and right eye. Even in the healthy visual system there is often a small imbalance in the strength of these connections projecting to the brain. ‘Eye dominance’ provides a measure of the perceptual dominance of one eye over the other. Theoretical models suggest that eye dominance is related to reciprocal inhibition between monocular units in the primary visual cortex, the first location where the binocular input is combined. As the specific inhibitory interactions in the binocular visual system critically depend on the presence of visual input, we sought to test the role of inhibition by measuring the inhibitory (GABA) neurotransmitters during monocular visual stimulation of the dominant and the non-dominant eye. GABA levels were acquired in a single volume of interest in the early visual cortex, including V1 from both hemispheres, using a combined functional magnetic resonance imaging and magnetic resonance spectroscopy (combined fMRI-MRS) sequence on a 7-Tesla MRI scanner. Individuals with stronger eye dominance had a greater difference in GABAergic inhibition between the eyes. This relationship was present only when the visual system was actively processing sensory input and was not present at rest. We provide the first evidence that imbalances in GABA levels during ongoing sensory processing are related to eye dominance in the human visual cortex. Our finding supports the view that intracortical inhibition underlies normal eye dominance.
GABA spectroscopy
edited GABA 1H MEGA-PRESS spectra
GABA-edited
Magnetic Resonance Spectroscopy, MRI, Human Connectome, 2-HG, 2-hydroxyglutarate, zoom, zoom MRSI, reduced field of View, rFOV, Cerebellum, High-resolution, IDH, Isocitrate, IDH1, IDH2, Cancer, Glioma, Parcellation, Macro Anatomical
Functional
Myeloarchitectonic
functional MRS
MR Spectroscopy Study Group
fMRI - fMRSI
glutamate
gaba
fMRS
ISMRM
standardization
Across-vendor
semi-LASER
single-voxel
MRS
3T
human brain mapping
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Bordettela is a gram negative cocobacilli spread by air born drop let
Richard's aventures in two entangled wonderlands
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
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Fast 3D-P31-MRSI Using Custom Rosette Petal Trajectory at 3T with 4x Accelera...
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https://lnkd.in/gnjCHtu2
Submillimeter fMRI Acquisition using a dual-echo Rosette kspace trajectory at 3T
n this study, we overcome the technological barrier against acquiring submillimeter resolution (~ 0.5 mm) fMRI data at 3T via a novel dual-echo Rosette k-space design. This design results in the fine representation of activation maps in two different functional tasks and might be a springboard in neuroimaging by providing very high-resolution spatiotemporal dynamics of neural networks. The method will be further evolved with the feedback from the MRI community via the GitHub platform as such for further acceleration, inflow saturation, and 3D coverage via 3D sampling and/or multiband approaches.
rosette fmri very high resolution at 3T
rosette fmri very high resolution at 3T
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Laminar fMRI at 3T using Dual-echo Rosette with a TE= 15 us
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3D-UTE Rosette MRI and MRSI at UHF human (7T) and animal scanners (9.4T) usin...
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3D-UTE Rosette Applications (MRI and MRSI) at UHF human (7T) and animal scanners (9.4T) using The Berkeley Advanced Reconstruction Toolbox (BART) toolbox
Uzay Emir
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Time: 15:45-16:45
Simultaneous Measurement of functional MRI and MRS by Fast Non-water Suppress...
The non-water suppressed magnetic resonance spectroscopic imaging (MRSI) sequence with concentric k-space trajectory was proposed to measure functional MRI and MRSI signals simultaneously. A right-hand finger-tapping task was performed at 3T MRI scanner to test the simultaneous hemodynamic and neurochemical measurements in the human primary motor cortex. The results showed a significant overlap betweenT2* and metabolite (glutamate) changes.
Quantitative Susceptibility Mapping (QSM) Using High-resolution Ultra-Short E...
Karnik A, Shen X, Monsivais H, Sunjar A, Özen A, Ilbey S, Chiew M, Cakmak M, Rispoli J, Emir UE., Quantitative Susceptibility Mapping (QSM) Using High-resolution Ultra-Short Echo Time (UTE) MRI with Rosette k-space Pattern International Society for Magnetic Resonance in Medicine Annual Meeting 2022
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Event-Related fMRS A transient break in excitatory-inhibitory balance
Time-Resolved fMRI-fMRS measures simultaneous Neurotransmitters and BOLD-fMRI...
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Detection of oncogenic IDH1 mutations using magnetic resonance spectroscopy of 2-hydroxyglutarate
standardization
Across-vendor
semi-LASER
single-voxel
MRS
3T
GABA spectroscopy
edited GABA 1H MEGA-PRESS spectra
GABA-edited
Magnetic Resonance Spectroscopy, MRI, Human Connectome, 2-HG, 2-hydroxyglutarate, zoom, zoom MRSI, reduced field of View, rFOV, Cerebellum, High-resolution, IDH, Isocitrate, IDH1, IDH2, Cancer, Glioma, Parcellation, Macro Anatomical
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fMRS
ISMRM
standardization
Across-vendor
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GABAergic inhibition in the human visual cortex relates to eye dominance
Binocular vision is created by fusing the separate inputs arriving from left and right eye. Even in the healthy visual system there is often a small imbalance in the strength of these connections projecting to the brain. ‘Eye dominance’ provides a measure of the perceptual dominance of one eye over the other. Theoretical models suggest that eye dominance is related to reciprocal inhibition between monocular units in the primary visual cortex, the first location where the binocular input is combined. As the specific inhibitory interactions in the binocular visual system critically depend on the presence of visual input, we sought to test the role of inhibition by measuring the inhibitory (GABA) neurotransmitters during monocular visual stimulation of the dominant and the non-dominant eye. GABA levels were acquired in a single volume of interest in the early visual cortex, including V1 from both hemispheres, using a combined functional magnetic resonance imaging and magnetic resonance spectroscopy (combined fMRI-MRS) sequence on a 7-Tesla MRI scanner. Individuals with stronger eye dominance had a greater difference in GABAergic inhibition between the eyes. This relationship was present only when the visual system was actively processing sensory input and was not present at rest. We provide the first evidence that imbalances in GABA levels during ongoing sensory processing are related to eye dominance in the human visual cortex. Our finding supports the view that intracortical inhibition underlies normal eye dominance.
GABA spectroscopy
edited GABA 1H MEGA-PRESS spectra
GABA-edited
Magnetic Resonance Spectroscopy, MRI, Human Connectome, 2-HG, 2-hydroxyglutarate, zoom, zoom MRSI, reduced field of View, rFOV, Cerebellum, High-resolution, IDH, Isocitrate, IDH1, IDH2, Cancer, Glioma, Parcellation, Macro Anatomical
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MR Spectroscopy Study Group
fMRI - fMRSI
glutamate
gaba
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standardization
Across-vendor
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single-voxel
MRS
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Submillimeter fMRI Acquisition using a dual-echo Rosette kspace trajectory
Ultra-Short Echo Time 31P 3D MRSI at 3T with Novel Rosette k-space Trajectory
Ultra-Short Echo Time 31P 3D MRSI at 3T with Novel Rosette k-space Trajectory
Submillimeter fMRI Acquisition using a dual-echo Rosette kspace trajectory at 3T
Submillimeter fMRI Acquisition using a dual-echo Rosette kspace trajectory at 3T
Laminar fMRI at 3T using Dual-echo Rosette with a TE= 15 us
Laminar fMRI at 3T using Dual-echo Rosette with a TE= 15 us
3D-UTE Rosette MRI and MRSI at UHF human (7T) and animal scanners (9.4T) usin...
3D-UTE Rosette MRI and MRSI at UHF human (7T) and animal scanners (9.4T) usin...
Simultaneous Measurement of functional MRI and MRS by Fast Non-water Suppress...
Simultaneous Measurement of functional MRI and MRS by Fast Non-water Suppress...
Quantitative Susceptibility Mapping (QSM) Using High-resolution Ultra-Short E...
Quantitative Susceptibility Mapping (QSM) Using High-resolution Ultra-Short E...
High Resolution 3D Ultra-Short Echo Time MRI with Rosette k-Space Pattern for...
High Resolution 3D Ultra-Short Echo Time MRI with Rosette k-Space Pattern for...
1H/31P 3D MRSI at 3T with Novel Rosette k-space Trajectory with compressed se...
1H/31P 3D MRSI at 3T with Novel Rosette k-space Trajectory with compressed se...
CMRR workshop in vivo GABA Glutamate and fMRI BOLD imaging Event-Related fMRS
CMRR workshop in vivo GABA Glutamate and fMRI BOLD imaging Event-Related fMRS
Time-Resolved fMRI-fMRS measures simultaneous Neurotransmitters and BOLD-fMRI...
Time-Resolved fMRI-fMRS measures simultaneous Neurotransmitters and BOLD-fMRI...
Proposing an Accelerated Magnetic Resonance Spectroscopic Imaging Acquisition...
Proposing an Accelerated Magnetic Resonance Spectroscopic Imaging Acquisition...
GABAergic inhibition in the human visual cortex relates to eye dominance
GABAergic inhibition in the human visual cortex relates to eye dominance
Recently uploaded
bordetella pertussis.................................ppt
Bordettela is a gram negative cocobacilli spread by air born drop let
Richard's aventures in two entangled wonderlands
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...
Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...University of Maribor
Slides from talk:
Aleš Zamuda: Remote Sensing and Computational, Evolutionary, Supercomputing, and Intelligent Systems.
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Inter-Society Networking Panel GRSS/MTT-S/CIS Panel Session: Promoting Connection and Cooperation
https://www.etran.rs/2024/en/home-english/Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
Seminar of U.V. Spectroscopy by SAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Travis Hills' Endeavors in Minnesota: Fostering Environmental and Economic Pr...
Travis Hills of Minnesota developed a method to convert waste into high-value dry fertilizer, significantly enriching soil quality. By providing farmers with a valuable resource derived from waste, Travis Hills helps enhance farm profitability while promoting environmental stewardship. Travis Hills' sustainable practices lead to cost savings and increased revenue for farmers by improving resource efficiency and reducing waste.
20240520 Planning a Circuit Simulator in JavaScript.pptx
Evaporation step counter work. I have done a physical experiment.
(Work in progress.)
ISI 2024: Application Form (Extended), Exam Date (Out), Eligibility
The Indian Statistical Institute (ISI) has extended its application deadline for 2024 admissions to April 2. Known for its excellence in statistics and related fields, ISI offers a range of programs from Bachelor's to Junior Research Fellowships. The admission test is scheduled for May 12, 2024. Eligibility varies by program, generally requiring a background in Mathematics and English for undergraduate courses and specific degrees for postgraduate and research positions. Application fees are ₹1500 for male general category applicants and ₹1000 for females. Applications are open to Indian and OCI candidates.
Leaf Initiation, Growth and Differentiation.pdf
Leaf initiation, growth and differentiation, genetic control of leaf development.
Orion Air Quality Monitoring Systems - CWS
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
THEMATIC APPERCEPTION TEST(TAT) cognitive abilities, creativity, and critic...
THEMATIC APPERCEPTION TEST(TAT) cognitive abilities, creativity, and critic...Abdul Wali Khan University Mardan,kP,Pakistan
hematic appreciation test is a psychological assessment tool used to measure an individual's appreciation and understanding of specific themes or topics. This test helps to evaluate an individual's ability to connect different ideas and concepts within a given theme, as well as their overall comprehension and interpretation skills. The results of the test can provide valuable insights into an individual's cognitive abilities, creativity, and critical thinking skillsToxic effects of heavy metals : Lead and Arsenic
Heavy metals are naturally occuring metallic chemical elements that have relatively high density, and are toxic at even low concentrations. All toxic metals are termed as heavy metals irrespective of their atomic mass and density, eg. arsenic, lead, mercury, cadmium, thallium, chromium, etc.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
3D Hybrid PIC simulation of the plasma expansion (ISSS-14)
3D Particle-In-Cell (PIC) algorithm,
Plasma expansion in the dipole magnetic field.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
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bordetella pertussis.................................ppt
bordetella pertussis.................................ppt
Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...
Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...
Travis Hills' Endeavors in Minnesota: Fostering Environmental and Economic Pr...
Travis Hills' Endeavors in Minnesota: Fostering Environmental and Economic Pr...
20240520 Planning a Circuit Simulator in JavaScript.pptx
20240520 Planning a Circuit Simulator in JavaScript.pptx
ISI 2024: Application Form (Extended), Exam Date (Out), Eligibility
ISI 2024: Application Form (Extended), Exam Date (Out), Eligibility
PRESENTATION ABOUT PRINCIPLE OF COSMATIC EVALUATION
PRESENTATION ABOUT PRINCIPLE OF COSMATIC EVALUATION
Mudde & Rovira Kaltwasser. - Populism - a very short introduction [2017].pdf
Mudde & Rovira Kaltwasser. - Populism - a very short introduction [2017].pdf
THEMATIC APPERCEPTION TEST(TAT) cognitive abilities, creativity, and critic...
THEMATIC APPERCEPTION TEST(TAT) cognitive abilities, creativity, and critic...
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...
3D Hybrid PIC simulation of the plasma expansion (ISSS-14)
3D Hybrid PIC simulation of the plasma expansion (ISSS-14)
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...