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Substrate-Independent
        Minds
     Randal A. Koene
     Carboncopies.org




                        1
DYSTOPIA




           2
SELECTION




            3
EMPATHY




          4
CHALLENGES




             5
AUGMENTED




            6
BEING




        7
SUBSTRATE-
INDEPENDENT
MINDS




                 WHOLE
                  BRAIN
              EMULATION8
SYSTEM IDENTIFICATION
ROADMAP
REQUIREMENTS




               11
SCOPE
RESOLUTION




             12
EMULATION
PLATFORM    80 million ATP per action
            potential
            Brain: 20-40W (20-44% of
            body)
            Average action potential
            takes 1.5ms
            About 4nW per event
            Supports 7 billion
            concurrent events
            Average rate 4-7Hz... 470
            billion events/s
                                   13
STRUCTURAL
CONNECTOME




             14
15
16
FUNCTIONAL
CHARACTERIZATION




                   17
MOLECULAR
TICKER TAPE




      Kording (Northwestern), Boyden (MIT), Church (Harvard), Koene   18
FUNCTIONALIZED
NANOPARTICLES
WIRELESS
MICROPROBES




              Gomez-Martinez et al. (2009)
                                       20
21
TEAM
NETWORK

          2um   1um




                      22
Carboncopies.org
B



BODY




           BRAIN
Thank You
    carboncopies.org
randal.a.koene@carboncopies.org



                                  25

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Dr. Randal Koene: Substrate-Independent Minds (Australian Singularity Summit 2012)

Editor's Notes

  1. General concept of demux tree Specific implementation via nanowires, Rudolpho Llinas NYU School of Med, 500nm polymer or platinum wires
  2. General concept of demux tree Specific implementation via nanowires, Rudolpho Llinas NYU School of Med, 500nm polymer or platinum wires
  3. You choose a modeling resolution At it and below, functional characterization is key; the components must be simple enough to capture all their relevant behavior Above it, structural characterization is key; the interaction of components and their emergent product; connectome Function-structure in neuronal networks, and hardware/software – both are actually very similar in any other complex system, including computers You can use concurrent functional characterization and low-res structural information (e.g. finding all neurons) to infer functional connectivity – but there is risk of missing latent functions You can reduce the signal dimensions – considering only spatial architectural information (morphology) instead of spatial and temporal information (responses) by combining high-res structural information with inference of “functional type” - but even with a complete library of types and their paramter-related distributions of behaviors, there there is risk that mapping may not be one-to-one and that spatial data errors (e.g. misreadings of component sizes) may be cumulative and may be hard to correct without the addition of locally gathered functional information It is also better in general to rebuild a complex system bit by bit, while carrying out validation that it still works
  4. Red blood cell diameter 8um. Existing biopassive & bioactive coatings for neural implants. Passes through every capillary to every neuron in the brain. Chip in cell has been done Artificial red blood cell has been done
  5. Teams: Hub cell (8um), sensor, stimulation, herding, chains, tag delivery, morphology recording agents (1-2um)