The document discusses the significant impact of microscopes and digital technology on medicine, tracing back to Anton van Leeuwenhoek's innovations in microscopy in 1674. It highlights how advancements in technology, such as genomics and the internet, allow for greater understanding and exploration of both small and large-scale constructs in medicine. The text emphasizes the importance of using technology to enhance human connection and knowledge while maintaining the essence of human spirit in healthcare.

1. The Microscope and theThe Microscope and the
MegamacroscopeMegamacroscope
(The Internet and The Digital(The Internet and The Digital
Age):Age):
Impact on Medicine’s future!Impact on Medicine’s future!
Kim Solez, M.D.Kim Solez, M.D.

2. SlideSlide 22
Visioning Broadly Defined!Visioning Broadly Defined!
The Microscope.The Microscope.
When Anton Van Leeuwenhoek built the firstWhen Anton Van Leeuwenhoek built the first
practical microscope in Holland in 1674 itpractical microscope in Holland in 1674 it
changed the horizons of human beings forever,changed the horizons of human beings forever,
allowing them to see with their own eyes theallowing them to see with their own eyes the
structure of life itself. Today's high sciencestructure of life itself. Today's high science
marvels - gene chip technology,laser capturemarvels - gene chip technology,laser capture
microdissection, genomics, and proteomics - are amicrodissection, genomics, and proteomics - are a
direct extension of Van Leeuwenhoek's originaldirect extension of Van Leeuwenhoek's original
discovery.discovery.

3. SlideSlide 33
Visioning Broadly Defined!Visioning Broadly Defined!
The Microscope.The Microscope.

4. SlideSlide 44
Visioning Broadly Defined!Visioning Broadly Defined!
The Microscope.The Microscope.
Anton Van Leeuwenhoek’s original microscope hadAnton Van Leeuwenhoek’s original microscope had
magnifications of 270 diameters and a simplemagnifications of 270 diameters and a simple
screw thread focus adjustmentscrew thread focus adjustment

5. SlideSlide 55
Visioning Broadly Defined!Visioning Broadly Defined!
The Microscope. Long Life.The Microscope. Long Life.
Van Leeuwenhoek lived 91 years (1632-1723) andVan Leeuwenhoek lived 91 years (1632-1723) and
during his long life he used his lenses to makeduring his long life he used his lenses to make
pioneering studies on an extraordinary variety ofpioneering studies on an extraordinary variety of
things, both living and non-living, reporting histhings, both living and non-living, reporting his
findings in over a hundred letters to the Royalfindings in over a hundred letters to the Royal
Society of England and the French Academy.Society of England and the French Academy.

6. SlideSlide 66
Visioning Broadly Defined! TheVisioning Broadly Defined! The
Microscope. Long Life.Microscope. Long Life.
Knowledge.Knowledge.In 1716 at the age of 84 he wrote:In 1716 at the age of 84 he wrote:
"My work, which I've done for a long time, was not"My work, which I've done for a long time, was not
pursued in order to gain the praise I now enjoy,pursued in order to gain the praise I now enjoy,
but chiefly from a craving after knowledge, whichbut chiefly from a craving after knowledge, which
I notice resides in me more than in most otherI notice resides in me more than in most other
men. And therewithal, whenever I found outmen. And therewithal, whenever I found out
anything remarkable, I have thought it my duty toanything remarkable, I have thought it my duty to
put down my discovery on paper, so that allput down my discovery on paper, so that all
ingenious people might be informed thereof."ingenious people might be informed thereof."

7. SlideSlide 77
The Internet /Digital Age: ExaminingThe Internet /Digital Age: Examining
the basic structure of information itself.the basic structure of information itself.
..
Knowledge and information were of foremostKnowledge and information were of foremost
importance to Van Leeuwenhoek. Todayimportance to Van Leeuwenhoek. Today
computers, the Internet, the Digital Age, allow uscomputers, the Internet, the Digital Age, allow us
to examine the basic structure of informationto examine the basic structure of information
itself.itself.

8. SlideSlide 88
The Internet /Digital Age: Seeing BigThe Internet /Digital Age: Seeing Big
Things: The MegamacroscopeThings: The Megamacroscope..
Microscope means "seeing small things". Today's connectedMicroscope means "seeing small things". Today's connected
computers of the Internet allow us to see andcomputers of the Internet allow us to see and
conceptualize very big things, constructs that otherwiseconceptualize very big things, constructs that otherwise
would be completely out of our reach. So connectedwould be completely out of our reach. So connected
computers become "Megamacroscopes" and again thecomputers become "Megamacroscopes" and again the
horizon has been changed very greatly. Connectionshorizon has been changed very greatly. Connections
between people and ideas are being made at anbetween people and ideas are being made at an
increasing rate that benefit every area of humanincreasing rate that benefit every area of human
endeavor.endeavor.

9. SlideSlide 99
Capturing the imagination ofCapturing the imagination of
the public and health carethe public and health care
providers.providers.Providing a future vision of the benefits ofProviding a future vision of the benefits of
technology without losing the higher elements oftechnology without losing the higher elements of
the human spirit.the human spirit.
1.1. Data compression.Data compression.
2.2. Point of service information.Point of service information.
3.3. High impact education.High impact education.
4.4. Measuring impact of interventions on health.Measuring impact of interventions on health.

10. SlideSlide 99
Capturing the imagination ofCapturing the imagination of
the public and health carethe public and health care
providers.providers.Providing a future vision of the benefits ofProviding a future vision of the benefits of
technology without losing the higher elements oftechnology without losing the higher elements of
the human spirit.the human spirit.
1.1. Data compression.Data compression.
2.2. Point of service information.Point of service information.
3.3. High impact education.High impact education.
4.4. Measuring impact of interventions on health.Measuring impact of interventions on health.