3. Dtpa renogram
• Dtpa preparation:
1.Allow the kit vial to attain ambient tempeature.
2. Add 2-3ml of sterile sodium pertechnetate (Na99mTcO4
) in 0.9% sodium chloride
solution containing the required activity of 99mTc and mix well.
3. Keep the vial in boiling water bath for 5 min (alternately at room
temperature for
about 15 min).
4. Remove the vial from water bath and allow it to cool for 10 min.
5. The preparation is now ready for use.
4. Localization: glomerular filtration and
Is purely filtered by the glomerulus and
excreted through the urinary system
and bladder.
Dose
Adult- 5-10mciPediatrics- 0.05 mCi/kg
Mode of administration:IV
Indications:
•Evaluation for renal artery stenosis, obstruction, and/or trauma.
• Evaluation of renal tubular function and perfusion (glomerular filtration) for blood flow,
parenchyma, and excretion.
• Evaluation of renal vascular flow •Evaluation of a kidney transplant
Patient preparation:
Instruct the patient to be NPO (liquids only) for at least 4 hours on morning before study. Instruct the patient to hydrate well (water;
up to 10 mL/kg) and void just before test.hydration should continue between studies. Dehydration causes delayed uptake and
clearance.
5. • INSTRUMENTATION
• Gamma camera: Large field of view
• Collimator: Low energy, high resolution, parallel hole
• Photopeak: 15%-20% window centered over 140 keV
• POSITIONING
• Routine renal: Supine, camera posterior
• Renal transplant: Camera anterior over allograft
• .
6. • COMPUTER ACQUISITION
• Blood flow: 1- to 2-second frames for 60 seconds
• Dynamic: 30-second frames for 25-30 minutes
• Prevoid image: 500k count
• Postvoid image
• PROCESSING
• Draw region of interest around kidneys.
• Draw background area next to each kidney.
• Generate time-activity curves for flow and dynamic
• phases.
• Generate differential function calculation
7. Ec renogram
• Ec preparation
1. Allow the kit vials to attain ambient temperature.
2. Add 2 ml of sterile sodium pertechnetate (Na99mTcO4) solution
containing upto 50 mCi (1.85 GBq) to Component-A vial (reaction vial).
Allow it to stand at room temperature for 10 min.
3. Add 1 ml of water for injection/saline to Component-B vial and mix well.
4. Aseptically transfer the contents of Component-B vial to Component-A
vial (reaction vial) and heat in boiling water bath for 10 min.
5. Allow it to stand at room temperature for 5 min.
6. Add 0.5ml of Component-C to the reaction vial to adjust pH to ~ 7.
7. The preparation is now ready for use.
8. • Dose : 5-6 mci (adults)
• 1.5-2 mci/kg (children)
• Indication:
Hydroneprosis
Puj obstruction
Aqusition :
Inject Tc-99m EC followed by 40mg Lasix on table
Imaging-20 min:
full syringe
Flow
Prevoid
Empty syringe
Postvoid
delay
9. dmsa
• Tc-99m DMSA
• Child: 50 μCi/kg (minimum dose of 600 μCi)
• Adult: 5 mCi (185 MBq)
Mode of administration : IV
LOCALISATION:
90% binds to plasma proteins, preventing any significant glomerular filtration, hence slow clearance from renal cortex (proximal
convoluted tubules) with 40%-50% of the injected dose localizing in the proximal tubules of the cortex. Only
10% excreted through the urine in the first several hours
INDICATION:
Evaluation of renal cortex
Detection and locallzation of renal mass (space-occupying lesions)
• INSTRUMENTATION
• Planar gamma camera: Large-field-of-view, parallel-hole collimator for differential calculation. Pinhole collimator for cortical
images. Converging collimator may be used for adults. SPECT: Dual- or triple-head preferred
10. • IMAGING PROCEDURE
• Patient should void before starting.
• Inject radiopharmaceutical intravenously.
• Image at 2 hours after injection.
• Acquire parallel collimator images for 500k on anterior and posterior
views for differential calculation.
• Pinhole images acquire for 100k counts per view.
• Position patient (RAO LAO)so each kidney is imaged separately, but
camera is equidistance from patient.
11. • Dmsa preparation:
1. Allow the kit vial to attain ambient temperature
2. add req activity 20mci (max 50)
3. Allow it to stand at room temperature for 15 min.
4. The preparation is now ready for use
