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1. 8/18/2020 Is Cannabis Effective for Incontinence?
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CANNABIS FOR INCONTINENCE
Is Cannabis Effective for
Incontinence?
What can medical marijuana do for incontinence?

2. 8/18/2020 Is Cannabis Effective for Incontinence?
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Posted by:
Lemon Knowles, today at 12:00am
Is Cannabis Effective for Incontinence?
Urinary incontinence is nothing new. It can happen to any person but becomes more prominent
with age. Sometimes it is just a small leaking, but often it becomes uncontrollable and the person
su ering from incontinence is bound to wear protective wear like adult diapers or pads. Women
su er twice as much as men due to their physiology.
Most often it happens when the muscles are too weak or too active. When your muscles are too
weak, even a sneeze, lifting a heavy object, or laughing could let you wet your pants. This is called
stress incontinence. When the muscles are overactive, you might have a constant urge to urinate
even if your bladder is empty.
This reminds us often of little kids when they have to go. The crossing of the legs and stutter
walking to get to the restroom as fast as possible. More people su er from this than is commonly
known.
How is Urinary Continence De ned?
Urinary continence is seen as a loss of bladder control. Sometimes it is due to biological factors like
weak bladder muscles or in ammation. Some nerve damage associated with diseases like multiple
sclerosis or Parkinson´s disease also is at play. An overactive bladder is also known as a spastic

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bladder or detrusor overactivity. As it is sometimes embarrassing, people su ering from this
condition also tend to carry more stress.
Di erent Kinds of Incontinence
Most people experience minor leaks or spots, but some lose small amounts of urine more
frequently. These are the di erent types of incontinence people are dealing with:
Stress incontinence – This happens when there is sudden pressure on the bladder by coughing,
laughing, sneezing, exercising, or lifting something heavy.
Urge incontinence – When a sudden intense urge is experienced to urinate that is followed by an
involuntary loss of urine. This condition could be caused by a minor issue or something more
severe like diabetes or a neurological disorder.
Over ow incontinence – a frequent experience or constant dribbling of urine because of a
bladder that doesn´t empty completely
Functional incontinence – A physical or mental impairment blocks you from getting to the toilet
in time. Something like severe arthritis could be the cause as it slows down movement.
Mixed incontinence – more than one of the above-mentioned conditions are at play
How does the bladder work?
The bladder is one of the simpler functioning organs in the body. The major structure at work is
the smooth detrusor muscle. To enable urinating, the lower detrusor muscle closer to the bottom
part of the bladder where it combines e orts with the urethral sphincter, contracts. When the
bladder is lling up, the muscle stays relaxed. Neural circuits in the brain and spinal cord let it
function healthily.
When there is damage to central inhibitory pathways or sensitization of nerve bers in the bladder,
it triggers bladder overactivity. When a child is potty trained, the bladder is controlled through
sensory inputs and control. But when the bladder is overactive, the communication is not as
smooth as desired.
How does Cannabis a ect Incontinence?
There are endocannabinoids found all over the bladder and its surrounding areas. Both the
cannabinoid receptors, CB1 and CB2, are also present. In a study in 2017, scientists discovered that
detrusor overactivity can be a ected by known agonists of the cannabinoid receptors. In the
urothelium, where the smooth detrusor muscle cells meet the sensory neurons, CB 1 activity show
promise as a modulator. It indicates that cannabis therapeutics can play a bene cial role.
When conventional medication is used, intending to calm the nerves. This is why cannabis is so
e ective as it has anti-in ammatory properties. Studies show that THC and CBD both show e cacy
against overactive bladder conditions.

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THC and CBD for Incontinence
In two random controlled trials, 426 male and female patients were used. All of them were also
diagnosed with multiple sclerosis. They were treated with THC/CBD capsules or oromucosal spray.
The studies showed that cannabis treatment had a relevant decrease in incontinence. There were
also no side-e ects encountered when the tablets were administrated. Some side-e ects like
headaches, dry mouth, and vomiting were experienced with the spray. But the side-e ects were
mild with regards to conventional medicine.
More clinical trials showed that the administration of cannabis-derived extracts improves bladder
control. It is even e ective for people with spinal cord injuries. More studies were done on patients
with advanced multiple sclerosis where a signi cant decreased urinary urgency, frequency, and
nocturia were experienced. Scientists found that there was a 38% reduction in incontinence
episodes. Extracts also show to reduce overactive bladder symptoms resistant to previous
treatments.
Afterthoughts
Cannabis as a viable treatment for incontinence is widely received by those who like a holistic
approach rather than conventional medications. It is a safe and e ective way to treat overactive
bladders. More studies are naturally necessary to determine if THC and CBD should be used in
combination, or if it is just as e ective when used alone.
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NEWS
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INTERVIEW
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