The America Invents Act takes effect in September 2012, bringing significant changes to US patent law. Key provisions include: 1. Supplemental examination allows patent owners to address issues to strengthen patents against certain challenges. 2. Third parties can submit prior art for pending patent applications. 3. Inter partes review replaces inter partes reexamination, allowing more challenges based on anticipation and obviousness. 4. Requirements for inventor oaths become more flexible. 5. Transitional post-grant review covers some business method patents. 6. Failure to obtain or present advice of counsel can no longer be used as evidence of willful infringement.