Examine the key differences between invasive and osmotic diarrhea in this comparative presentation. Explore the underlying mechanisms, clinical manifestations, and diagnostic considerations for each type of diarrhea. Learn about management strategies tailored to address the distinct pathophysiological processes involved, including pharmacological interventions, fluid and electrolyte replacement, and dietary modifications. Gain a deeper understanding of how recognizing these differences informs effective treatment approaches for patients experiencing diarrhea of various etiologies.
2. Diarrhoea:
• more than 3 bowel motions per day.
• stools are looser than normal.
• stool volume is more than 300g.
• can cause loss of fluids and electrolytes.
3. INVASIVE DIARRHOEA
• also known as inflammatory diarrhoea
• caused due to invasion of mucosa of the large bowel.
• the invasion leads to inflammation.
• it usually leads to bloody diarrhoea.
• it causes defective absorption of fluids and electrolytes.
• main causes are: shigella or e. histolytica dysentry, crohns disease.
4. complications of invasive diarrhoea:
• damage to intestinal mucosa.
• sepsis
• malnutrtion
• dehydration
• TREATMENT:
• rehydration therapy
• it is treated with antibiotics and anti diarrhoeal agents.
5. osmotic diarrhoea:
• caused due to generalised malabsorption, specific defect in
absorption like disaccaride deficiency.
• ingestion of poorly absorbed substance which retain fluid in the
lumen like magnesium, phosphate.
• high concentration of solute remains in the intestine.
• diarrhoea volume is decreased or moderate in this type.
• it tends to improve when oral intake stops.
• no blood in stool.
6. complications of osmotic diarrhoea:
• nutritional deficiency
• disbalance of electrolyes.
• Treatment:
• in case of disturbance of normal gut flora, we use antbiotics
• rehydration therapy.
