The document outlines the differences between invasive and osmotic diarrhoea. Invasive diarrhoea is characterized by inflammation of the large bowel and can lead to symptoms such as bloody stools, while osmotic diarrhoea results from malabsorption and causes moderate stool volume without blood. Treatment for both types includes rehydration therapy, with antibiotics used specifically for invasive diarrhoea.

1. difference between invasive
and osmotic diarrhoea
by Sunidhi Singh
IM 434

2. Diarrhoea:
• more than 3 bowel motions per day.
• stools are looser than normal.
• stool volume is more than 300g.
• can cause loss of fluids and electrolytes.

3. INVASIVE DIARRHOEA
• also known as inflammatory diarrhoea
• caused due to invasion of mucosa of the large bowel.
• the invasion leads to inflammation.
• it usually leads to bloody diarrhoea.
• it causes defective absorption of fluids and electrolytes.
• main causes are: shigella or e. histolytica dysentry, crohns disease.

4. complications of invasive diarrhoea:
• damage to intestinal mucosa.
• sepsis
• malnutrtion
• dehydration
• TREATMENT:
• rehydration therapy
• it is treated with antibiotics and anti diarrhoeal agents.

5. osmotic diarrhoea:
• caused due to generalised malabsorption, specific defect in
absorption like disaccaride deficiency.
• ingestion of poorly absorbed substance which retain fluid in the
lumen like magnesium, phosphate.
• high concentration of solute remains in the intestine.
• diarrhoea volume is decreased or moderate in this type.
• it tends to improve when oral intake stops.
• no blood in stool.

6. complications of osmotic diarrhoea:
• nutritional deficiency
• disbalance of electrolyes.
• Treatment:
• in case of disturbance of normal gut flora, we use antbiotics
• rehydration therapy.