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COMPANYHISTORY
• Founded in 1990 in the United
Kingdom.
• Leaders in the field of cosmetic
consumer research
• Expanded to the United States
in 2014
• Global research capabilities
ADVANTAGES
 Geographical Locations
 Markets Served
 Services Provided
 Subject Database
 Quality Assurance
 Expertise in testing
including internationally
sought after malodor judges
COMPANYOVERVIEW
 Industry experts in Consumer Product Testing
 Key Staff Average > 20 Years Experience
 Core Team Together > 15 Years
 3 Research Sites
 Perform Contract Testing Services
 Industry Recognized Published Experts
 35,000 Global Subject Database
QCREGULATIONS
 ISO 9001
 ICH GCP
 EMEA
 FDA compliant
 Monthly external QC audit
 Internal QC:
 Study documents
 EC approval
 Study active phase
SUBJECTDATABASE
 Our locations, experience, and strategic partnerships
ensure we will meet the enrollment benchmarks for your
clinical study.
 Global database of 35,000 panelists with full medical
histories
 Age range 0-70+
 Special consumer profiles – Habits and Brand Loyalty
SUBJECTDATABASE
 Recruiters have 20+ years of clinical trial expertise
 Exclusive SEO for recruiting specific demographics
 Physician partnerships for direct recruiting
 Highly effective recruiting strategy
 Community education, outreach, event sponsorships and PR
 Digital media: social media, banners, email marketing
 Word of mouth
 98% subject retention rate
SUBJECTDATABASE
 Ethnic Panels
 Indian
 Asian
 African
 Hispanic
NJFACILITY
 8,000 sq. ft. research facility
 Climatically controlled hot room accommodates
- 50 panellists
 Full service wash/changing facilities
 SPF suite & Spa
 Wash/locker room and changing area
 Spray room with extraction system
 Numerous treatment rooms
 Full service hair salon
 Imaging suite (Visia CR)
FLORIDAFACILITY
 11,000 sq. ft. research
facility
 2 Climatically controlled
hot room accommodates
- 50 panellists
 Full service
wash/changing facilities
 SPF suite & Spa
FLORIDAFACILITY
 Wash/locker room and
changing area
 Spray room with extraction
system
 Numerous treatment rooms
 Full service hair salon
 Imaging suite (Visia CR)
HOTROOM 50 SEAT CAPACITY
MARKETSSERVED
 Personal Care
 Toiletries
 OTC
 Skin Care
 Eye Care
 Hair Care
 Oral Care
SERVICESPROVIDED
SAFETY EFFICACY ACCEPTABILITY
SAFETY
 PRIMARY IRRITATION PATCH
TESTING
 Standard 1, 2 & 3 application patch tests
 96-Hour Patch Test
 Frosch & Kligman Soap Chamber Test
 SECONDARY IRRITATION PATCH
TESTING
 HRIPTs
 Jordan & King
 Kligman
 Shelanski
SERVICESPROVIDED
SAFETY
 Open Application
 Human Eye Direct and Non-
Instillation
 Comedogenicity
 Phototoxicity
 Photosensitization
 Home-Use
SERVICESPROVIDED
SPF
 SPF – Global Regulations
 ISO 24444
 Europe
 Australia/NZ
 Japan and Pacific Rim
 South Africa
 FDA
 USA & Canada
 SPF – Types of Study
 Water-resistant
 Very Water-Resistant
 Sweat-resistant
SERVICESPROVIDED
APD
 ANTI-PERSPIRANT STUDIES
 Gravimetric method
 “Hot room”
 DEODORANT STUDIES
 Hedonic & Intensity
 Axillae
 Feet
 Vests, Shirts, Socks
SERVICESPROVIDED
ANTIAGEING
TEST
 Anti-Wrinkle (Profilometry)
 Hyperpigmentation (Chromameter)
 Skin Elasticity (Cutometer)
 Moisturisation Test (Corneometer)
 Compare Skins at Specific Ages
CLAIM
 “Anti-Aging”
 “Makes my Skin Look 10 Years
Younger”
SERVICESPROVIDED
ANTIWRINKLE
PROFILOMETRY TEST
 Visual and Instrumental
Assessment
– Generate skin replicas using Silflo
– Perform LASER profiling
CLAIM
 “Anti-Wrinkle”
 “Wrinkle-Defense”
 “Reduces the appearance of wrinkles by x%
in x weeks”
SERVICESPROVIDED
FACIALIMAGING
 CANFIELD VISIA CR
 Image capture for wrinkles and fine lines, skin texture, coloration/evenness,
photodamage, vascular features and porphyrins (P. acnes)
 High Resolution
 Rapid Capture Time
 PreSet Lighting Modes
 Minimises Technician Error
 Produces great B/A images
SERVICESPROVIDED
SKINLIGHTENING
SKIN LIGHTENING
 Visual and Instrumental
Assessment
 Chromameter, Mexamater
CLAIM
 “Improves skin tone”
 “Improves skin luminosity”
 “Helps reduce the appearance of
hyper-pigmented age spots”
 “Brightens skin”
SERVICESPROVIDED
SKINFIRMNESS
 ELASTICITY / FIRMNESS
 Visual and/or Instrumental
 DTM, Cutometer
 CLAIM
 “Firming”
 “Improves the elasticity of your
skin”
SERVICESPROVIDED
MOISTURISATION
MOISTURISATION (Emollient)
 In-Use or Controlled Application
 Visual and/or Instrumental
Assessment
 TEWL
 Evaporimeter, Tewameter
CLAIM
 “Improves the skin’s natural
barrier”
 “Emollient”
 “Kind to skin”
SERVICESPROVIDED
MOISTURISATION
MOISTURISATION (Humectant)
 In-Use or Controlled Application
 Visual and/or Instrumental
Assessment
 Corneometer, Dermal Phase
Meter (NOVA)
CLAIM
 “Provides moisture-boosting
hydration”
 “Revitalizing Moisturiser”
 “Moisturises for up to x hours”
SERVICESPROVIDED
ANTIINFLAMMATORY
ANTI-INFLAMMATORY TEST
 Compromise skin with
 SLS (typically 0.75%)
 UV (typically 4x MED)
 Follow treated & untreated sites to
resolution (visual or blistering)
CLAIM
 “Anti-Inflammatory”
 “Restorative”
 “Skin soothing” (after sun)
SERVICESPROVIDED
OXIDATION
TISSUE OXYYGENATION STUDY
 Transcutometer monitor (TCM4)
 Partial oxygen (pO2) values
 8.5kPa (pre) to 10.5kPa (post)
CLAIM
 “Clinically proven to help increase
oxygen levels in the skin ”
SERVICESPROVIDED
LESION
LESION COUNT STUDIES
 Non-Inflamed:
 Microcysts
 Blackheads (open
comedones)
 Whiteheads (closed
comedones)
Inflamed:
 Pustules
 Papules
SERVICESPROVIDED
SLIMMING
SLIMMING STUDIES
 Lipid reduction
 Ultra-sound
 Circumference reduction
 Arms
 Thighs
 Tummy
 Weight reduction
 BMI
SERVICESPROVIDED
HAIRCARE
HAIR CARE SUDIES
 Anti-Dandruff
 Expert Graders
 Strengthening
 MTT (Mini Tensile Tester)
 Hair Brush Friction
Method
 Colour Retention
 Chromameter
SERVICESPROVIDED
HAIRCARE
HAIR CARE SUDIES
(Stylist / Panelist Assesments)
 Oiliness
 Anti-Frizz
 Colour Retention
 Shine
 Frizziness
 Bounce
 Volumising
 Refreshing properties
 Smell
 Feel
 Access to custom designed
instrumentation
SERVICESPROVIDED
OTHERSTUDIES
 Nappy Studies
 Baby Wipes
 Depilatory
 Feminine Hygiene
 Wear Tests
 Foundations, Mascaras, Lipsticks
 Nail Strength
SERVICESPROVIDED
ACCEPTABILITY
Taste Tests
 Healthy or Taste-Compromised
Panels
Wear Tests
 Contact Lens, Dentures Lipsticks,
Mascaras
Preference Tests
 Fragrances, Packaging
SERVICESPROVIDED
INVESTIGATOREXPERTISE
 Novel Protocol Design
 Skin Graders
 Odor Assessors
 Hair/Scalp Assessors
 Bioinstrumentation
 Recruitment
 CRF/eCRF Development and
Completion
CONSULTANTPHYSICIANS
UNITED KINGDON
Dr Anthony Ormerod, MB BS MRCP FRCP
Medical Director; Consultant
Dermatologist / Surgeon
Dr Geetha Kugan, MRCP DCH FROPCH
Consultant Paediatrician
Dr M Idrees, BSc MBBS DO MRCOphth
Practising Consultant Ophthalmologist
Dr John Simmons, MB BS FRCP
Practicing Consultant Pharmacokineticist
Rachel Holley
Practicing Midwife
Dr Mary Summerville, MB BS
Practicing Consultant Gynecologist
CONSULTANTPHYSICIANS
UNITED STATES
Dr Jerry Bagel, M.D.
Practicing Consultant Dermatologist
Dr John Edward Vine, M.D.
Practicing Consultant Dermatologist
Dr Jules Richter, M.D.
Practicing Consultant Internist
Dr Joyce Glazer, M.D.
Practicing Consultant Internist
Dr Stephen Hudis, DDS, FACP
Practising Consultant Dentist
Dr Suzanne K. Jadico, MD
Practicing Consultant Ophthalmologist
Dr Anita Saha, M.D. FACOG
Practicing Obstetrics and Gynecology
Dr Trefor Evans, Ph.D
Follicular Substantiation Expert
GLOBALRESEARCH

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Global Consumer Research Leader

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  • 2. COMPANYHISTORY • Founded in 1990 in the United Kingdom. • Leaders in the field of cosmetic consumer research • Expanded to the United States in 2014 • Global research capabilities
  • 3. ADVANTAGES  Geographical Locations  Markets Served  Services Provided  Subject Database  Quality Assurance  Expertise in testing including internationally sought after malodor judges
  • 4. COMPANYOVERVIEW  Industry experts in Consumer Product Testing  Key Staff Average > 20 Years Experience  Core Team Together > 15 Years  3 Research Sites  Perform Contract Testing Services  Industry Recognized Published Experts  35,000 Global Subject Database
  • 5. QCREGULATIONS  ISO 9001  ICH GCP  EMEA  FDA compliant  Monthly external QC audit  Internal QC:  Study documents  EC approval  Study active phase
  • 6. SUBJECTDATABASE  Our locations, experience, and strategic partnerships ensure we will meet the enrollment benchmarks for your clinical study.  Global database of 35,000 panelists with full medical histories  Age range 0-70+  Special consumer profiles – Habits and Brand Loyalty
  • 7. SUBJECTDATABASE  Recruiters have 20+ years of clinical trial expertise  Exclusive SEO for recruiting specific demographics  Physician partnerships for direct recruiting  Highly effective recruiting strategy  Community education, outreach, event sponsorships and PR  Digital media: social media, banners, email marketing  Word of mouth  98% subject retention rate
  • 8. SUBJECTDATABASE  Ethnic Panels  Indian  Asian  African  Hispanic
  • 9. NJFACILITY  8,000 sq. ft. research facility  Climatically controlled hot room accommodates - 50 panellists  Full service wash/changing facilities  SPF suite & Spa  Wash/locker room and changing area  Spray room with extraction system  Numerous treatment rooms  Full service hair salon  Imaging suite (Visia CR)
  • 10. FLORIDAFACILITY  11,000 sq. ft. research facility  2 Climatically controlled hot room accommodates - 50 panellists  Full service wash/changing facilities  SPF suite & Spa
  • 11. FLORIDAFACILITY  Wash/locker room and changing area  Spray room with extraction system  Numerous treatment rooms  Full service hair salon  Imaging suite (Visia CR)
  • 12. HOTROOM 50 SEAT CAPACITY
  • 13. MARKETSSERVED  Personal Care  Toiletries  OTC  Skin Care  Eye Care  Hair Care  Oral Care
  • 15. SAFETY  PRIMARY IRRITATION PATCH TESTING  Standard 1, 2 & 3 application patch tests  96-Hour Patch Test  Frosch & Kligman Soap Chamber Test  SECONDARY IRRITATION PATCH TESTING  HRIPTs  Jordan & King  Kligman  Shelanski SERVICESPROVIDED
  • 16. SAFETY  Open Application  Human Eye Direct and Non- Instillation  Comedogenicity  Phototoxicity  Photosensitization  Home-Use SERVICESPROVIDED
  • 17. SPF  SPF – Global Regulations  ISO 24444  Europe  Australia/NZ  Japan and Pacific Rim  South Africa  FDA  USA & Canada  SPF – Types of Study  Water-resistant  Very Water-Resistant  Sweat-resistant SERVICESPROVIDED
  • 18. APD  ANTI-PERSPIRANT STUDIES  Gravimetric method  “Hot room”  DEODORANT STUDIES  Hedonic & Intensity  Axillae  Feet  Vests, Shirts, Socks SERVICESPROVIDED
  • 19. ANTIAGEING TEST  Anti-Wrinkle (Profilometry)  Hyperpigmentation (Chromameter)  Skin Elasticity (Cutometer)  Moisturisation Test (Corneometer)  Compare Skins at Specific Ages CLAIM  “Anti-Aging”  “Makes my Skin Look 10 Years Younger” SERVICESPROVIDED
  • 20. ANTIWRINKLE PROFILOMETRY TEST  Visual and Instrumental Assessment – Generate skin replicas using Silflo – Perform LASER profiling CLAIM  “Anti-Wrinkle”  “Wrinkle-Defense”  “Reduces the appearance of wrinkles by x% in x weeks” SERVICESPROVIDED
  • 21. FACIALIMAGING  CANFIELD VISIA CR  Image capture for wrinkles and fine lines, skin texture, coloration/evenness, photodamage, vascular features and porphyrins (P. acnes)  High Resolution  Rapid Capture Time  PreSet Lighting Modes  Minimises Technician Error  Produces great B/A images SERVICESPROVIDED
  • 22. SKINLIGHTENING SKIN LIGHTENING  Visual and Instrumental Assessment  Chromameter, Mexamater CLAIM  “Improves skin tone”  “Improves skin luminosity”  “Helps reduce the appearance of hyper-pigmented age spots”  “Brightens skin” SERVICESPROVIDED
  • 23. SKINFIRMNESS  ELASTICITY / FIRMNESS  Visual and/or Instrumental  DTM, Cutometer  CLAIM  “Firming”  “Improves the elasticity of your skin” SERVICESPROVIDED
  • 24. MOISTURISATION MOISTURISATION (Emollient)  In-Use or Controlled Application  Visual and/or Instrumental Assessment  TEWL  Evaporimeter, Tewameter CLAIM  “Improves the skin’s natural barrier”  “Emollient”  “Kind to skin” SERVICESPROVIDED
  • 25. MOISTURISATION MOISTURISATION (Humectant)  In-Use or Controlled Application  Visual and/or Instrumental Assessment  Corneometer, Dermal Phase Meter (NOVA) CLAIM  “Provides moisture-boosting hydration”  “Revitalizing Moisturiser”  “Moisturises for up to x hours” SERVICESPROVIDED
  • 26. ANTIINFLAMMATORY ANTI-INFLAMMATORY TEST  Compromise skin with  SLS (typically 0.75%)  UV (typically 4x MED)  Follow treated & untreated sites to resolution (visual or blistering) CLAIM  “Anti-Inflammatory”  “Restorative”  “Skin soothing” (after sun) SERVICESPROVIDED
  • 27. OXIDATION TISSUE OXYYGENATION STUDY  Transcutometer monitor (TCM4)  Partial oxygen (pO2) values  8.5kPa (pre) to 10.5kPa (post) CLAIM  “Clinically proven to help increase oxygen levels in the skin ” SERVICESPROVIDED
  • 28. LESION LESION COUNT STUDIES  Non-Inflamed:  Microcysts  Blackheads (open comedones)  Whiteheads (closed comedones) Inflamed:  Pustules  Papules SERVICESPROVIDED
  • 29. SLIMMING SLIMMING STUDIES  Lipid reduction  Ultra-sound  Circumference reduction  Arms  Thighs  Tummy  Weight reduction  BMI SERVICESPROVIDED
  • 30. HAIRCARE HAIR CARE SUDIES  Anti-Dandruff  Expert Graders  Strengthening  MTT (Mini Tensile Tester)  Hair Brush Friction Method  Colour Retention  Chromameter SERVICESPROVIDED
  • 31. HAIRCARE HAIR CARE SUDIES (Stylist / Panelist Assesments)  Oiliness  Anti-Frizz  Colour Retention  Shine  Frizziness  Bounce  Volumising  Refreshing properties  Smell  Feel  Access to custom designed instrumentation SERVICESPROVIDED
  • 32. OTHERSTUDIES  Nappy Studies  Baby Wipes  Depilatory  Feminine Hygiene  Wear Tests  Foundations, Mascaras, Lipsticks  Nail Strength SERVICESPROVIDED
  • 33. ACCEPTABILITY Taste Tests  Healthy or Taste-Compromised Panels Wear Tests  Contact Lens, Dentures Lipsticks, Mascaras Preference Tests  Fragrances, Packaging SERVICESPROVIDED
  • 34. INVESTIGATOREXPERTISE  Novel Protocol Design  Skin Graders  Odor Assessors  Hair/Scalp Assessors  Bioinstrumentation  Recruitment  CRF/eCRF Development and Completion
  • 35. CONSULTANTPHYSICIANS UNITED KINGDON Dr Anthony Ormerod, MB BS MRCP FRCP Medical Director; Consultant Dermatologist / Surgeon Dr Geetha Kugan, MRCP DCH FROPCH Consultant Paediatrician Dr M Idrees, BSc MBBS DO MRCOphth Practising Consultant Ophthalmologist Dr John Simmons, MB BS FRCP Practicing Consultant Pharmacokineticist Rachel Holley Practicing Midwife Dr Mary Summerville, MB BS Practicing Consultant Gynecologist
  • 36. CONSULTANTPHYSICIANS UNITED STATES Dr Jerry Bagel, M.D. Practicing Consultant Dermatologist Dr John Edward Vine, M.D. Practicing Consultant Dermatologist Dr Jules Richter, M.D. Practicing Consultant Internist Dr Joyce Glazer, M.D. Practicing Consultant Internist Dr Stephen Hudis, DDS, FACP Practising Consultant Dentist Dr Suzanne K. Jadico, MD Practicing Consultant Ophthalmologist Dr Anita Saha, M.D. FACOG Practicing Obstetrics and Gynecology Dr Trefor Evans, Ph.D Follicular Substantiation Expert