International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCS...IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCS...IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCS...IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCS...IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCS...IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCS...IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCS...IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal
International Journal of Computer Science, Engineering and Applications (IJCS...IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCS...IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEAIJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCS...IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal
International Journal of Computer Science, Engineering and Applications (IJCS...IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCS...IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEAIJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
International Journal of Computer Science, Engineering and Applications (IJCSEA)IJCSEA Journal
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an open access peer-reviewed journal that publishes articles which contribute new results in all areas of the computer science, Engineering and Applications. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of computer science, Engineering and Applications.
All submissions must describe original research, not published or currently under review for another conference or journal.
Similar to International Journal of Computer Science, Engineering and Applications (IJCSEA) (20)
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
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Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
International Journal of Computer Science, Engineering and Applications (IJCSEA)
1. International Journal of Computer Science, Engineering and Applications (IJCSEA)
**** WJCI Indexed ****
ISSN: 2230 - 9916 (Online); 2231 - 0088 (Print)
http://airccse.org/journal/ijcsea/index.html
Scope & Topics
International Journal of Computer Science, Engineering and Applications (IJCSEA) is an
open access peer-reviewed journal that publishes articles which contribute new results in all
areas of the computer science, Engineering and Applications. The journal is devoted to the
publication of high quality papers on theoretical and practical aspects of computer science,
Engineering and Applications.
All submissions must describe original research, not published or currently under review for
another conference or journal.
Topics of interest include, but are not limited to, the following.
Algorithms and Bioinformatics
Computer Architecture and Real time Systems
Database and Data Mining
Dependable, reliable and autonomic computing
Distributed and parallel systems & algorithms
DSP/Image Processing/Pattern Recognition/Multimedia
Embedded system and software
Game and software engineering
Geographical Information Systems/ Global Navigation Satellite Systems (GIS/GNSS)
Grid and scalable computing
Intelligent Information & Database Systems
IT policy and business management
Mobile and ubiquitous computing
Modeling and Simulation
Multimedia systems and services
Networking and communications
Performance Evaluation
Programming Languages
Security and Information Assurance
Soft Computing (AI, Neural Networks, Fuzzy Systems, etc.)
Software Engineering
Web and internet computing
Theoretical computer science
Natural Language Processing
Operating Systems
Compiler Design
Computer Education
2. Paper Submission
Authors are invited to Submit papers for this journal through Email: ijcseajournal@airccse.org
or through Submission System. Submissions must be original and should not have been
published previously or be under consideration for publication while being evaluated for this
Journal.
Important Dates
Submission Deadline : August 13, 2022
Notification : September 13, 2022
Final Manuscript Due : September 21, 2022
Publication Date : Determined by the Editor-in-Chief
Contact us
Here's where you can reach us: ijcseajournal@yahoo.com (or) ijcseajournal@airccse.org
Submission System
https://coneco2009.com/submissions/imagination/home.html
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http://airccse.org/journal/ijcsea/index.html