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Interdisciplinary Training in
      Mathematical Biology Through
       Team-based Undergraduate
          Research and Courses
                              Jason Miller, Ph.D.
                          Department of Mathematics


                                                      JMM New Orleans
                                                        9 January 2011
Sunday, January 9, 2011                                                  1
Outline
        • A couple questions
        • ‘Convergence’
        • Truman’s program, my mantra
        • A Look at a Bigger Picture


                                        JMM New Orleans
                                          9 January 2011
Sunday, January 9, 2011                                    2
Undergraduate
                          Mathematical Biology
      • Is there a need for undergraduate degree programs
            in mathematical biology?
      • What would an undergraduate curriculum in
            mathematical biology look like?
      • Where would a mathematical biology program live?
            In a math department? A biology department?
            Separate from both?


                                                      JMM New Orleans
                                                        9 January 2011
Sunday, January 9, 2011                                                  3
JMM New Orleans
                            9 January 2011
Sunday, January 9, 2011                      4
JMM New Orleans
                            9 January 2011
Sunday, January 9, 2011                      5
JMM New Orleans
                            9 January 2011
Sunday, January 9, 2011                      6
JMM New Orleans
                            9 January 2011
Sunday, January 9, 2011                      7
JMM New Orleans
                            9 January 2011
Sunday, January 9, 2011                      8
‘Convergent’ teamwork is going to be a defining
          characteristic of 21st century science and
          mathematics.
                    It can’t be taught through a series of lectures.
                    It can’t be taught from a textbook or by reading a
                    journal paper.
                    It can’t be taught in a course for a (single) major.
          The above activities can motivate students and
          prepare them to learn to be ‘convergent’

                                                                 JMM New Orleans
                                                                   9 January 2011
Sunday, January 9, 2011                                                             9
It can be taught...
       • Our experience provides strong evidence that
             proper hands-on undergraduate research (or
             research-like) projects can train undergraduates to
             be ‘convergent’
       • Essential characteristics:
           •     it’s a real research project to the mentors
           •     mentors from different disciplines
           •     undergraduates from different disciplines
           •     long-term immersion
           •     students have sense of significant ownership
                                                           JMM New Orleans
                                                             9 January 2011
Sunday, January 9, 2011                                                       10
At Truman...
       • We’ve been building and revising an interdisciplinary
             training program in mathematics and biology
       • Bridging the epistemological gap between
             mathematics and biology.
       • NSF funded: UBM program (Interdisciplinary Training
             for Undergraduates in Biology and Mathematics) in
             2003, 2004, and 2009



                                These allowed us to make mistakes
                                so that others wouldn’t have to.
                                                            JMM New Orleans
                                                              9 January 2011
Sunday, January 9, 2011                                                        11
Truman’s Program
          “We are not trying to turn mathematics
          majors into biology majors, not are we trying
          to turn biology majors into mathematics
          majors. Rather, we are trying to bring both
          together at the intersection of the life and
          mathematical sciences to train them to work
          across disciplinary boundaries.”


                                                   JMM New Orleans
                                                     9 January 2011
Sunday, January 9, 2011                                               12
Why, then?
     • Pre-Bio2010 selfishness!
     • We had math faculty who wanted to re-engage in
           research, learn about mentoring undergraduates;
           open-minded biologists
     • Students (in CS) were ahead of us, learning
           bioinformatics
     • Had some limited internal support:
      • Truman had a culture (outside the math
               department) that valued undergraduate research
         • Summer research grants for students           JMM New Orleans
                                                           9 January 2011
Sunday, January 9, 2011                                                     13
Truman’s Program
      • Our ‘program’ grew out of our undergraduate
            research program, conversations with others in our
            community
           • HHMI, SMB, MAA BIOSIGMAA, BioQUEST, MAA
                 PREP, NIMBioS, MBI, NSF UBM PI meetings, CUR,
                 NCUR
      • We have an interdisciplinary minor in mathematical
            biology
      • The minor requires a high-quality, interdisciplinary
            research experience (on- or off-campus)
                                                        JMM New Orleans
                                                          9 January 2011
Sunday, January 9, 2011                                                    14
Why, now?
    • Having been institutionalized (curriculum), we have
         internal and external pressures to continue to succeed
    • Truman still values undergraduate research (even in the
         mathematics department)
    • Faculty are getting results (publications, grants)
    • Contributing to national need for ‘convergent’ or
         interdisciplinary scientists and mathematicians
    • Desire to broaden participation in science and
         mathematics undergraduate degree programs

                                                           JMM New Orleans
                                                             9 January 2011
Sunday, January 9, 2011                                                       15
Looking back...
               • The scope of what we have now would not
                     be possible without the UBM grants
               • The essence of what we are doing could
                     continue without external funding *but not
                     without internal funding)
               • What we are doing, others can do.

                                                             JMM New Orleans
                                                               9 January 2011
Sunday, January 9, 2011                                                         16
There’s no STEM
                           without an M
        • Last week, the House and Senate reauthorized the
              America COMPETES act
        • The America COMPETES Act is a response to ‘Rising
              Above the Gathering Storm’ report
        • The ‘Rising Above the Gathering Storm’ report
              communicates the reasons America needs to
              increase its production of STEM professionals
        • As a result, we have many ‘STEM Talent Expansion’
              programs fromt he NIH, NSF, etc.
                                                          JMM New Orleans
                                                            9 January 2011
Sunday, January 9, 2011                                                      17
There’s no STEM
                           without an M
        • Preparing ‘convergent’ scientists is an aspect of this
              (scientists for the 21st century)
        • This can’t happen without involvement from the
              mathematics community.
        • What our small community is learning about how to
              collaborate with biologists can be (and should be)
              applied to working with other disciplines and multi-
              disciplinary teams.

                                                           JMM New Orleans
                                                             9 January 2011
Sunday, January 9, 2011                                                       18
Minor’s Outcomes
                             • Data Acquisition
                             • Modeling
                             • Computation
                             • Statistics
                             • Research


                                                  JMM New Orleans
                                                    9 January 2011
Sunday, January 9, 2011                                              19
Requirements
               • Demonstrate proficiencies in each category
                     (though research, courses)
               • Earn 15+ credits doing so (must take Intro to
                     MathBio course)
               • Attend MathBio Seminar
               • Participate in two half-semester program
                     workshops/seminars

                                                            JMM New Orleans
                                                              9 January 2011
Sunday, January 9, 2011                                                        20
http://mathbio.truman.edu




      This material is based upon work supported by the National Science Foundation under NSF
      UBM #0337769, #0436348, and #0926737.             Any opinions, findings, and conclusions or
      recommendations expressed in this material are those of the author(s) and do not necessarily
      reflect the views of the National Science Foundation.

                                                                                       JMM New Orleans
                                                                                         9 January 2011
Sunday, January 9, 2011                                                                                   21

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Interdisciplinary Training in Mathematical Biology Through Team-based Undergraduate Research and Courses

  • 1. Interdisciplinary Training in Mathematical Biology Through Team-based Undergraduate Research and Courses Jason Miller, Ph.D. Department of Mathematics JMM New Orleans 9 January 2011 Sunday, January 9, 2011 1
  • 2. Outline • A couple questions • ‘Convergence’ • Truman’s program, my mantra • A Look at a Bigger Picture JMM New Orleans 9 January 2011 Sunday, January 9, 2011 2
  • 3. Undergraduate Mathematical Biology • Is there a need for undergraduate degree programs in mathematical biology? • What would an undergraduate curriculum in mathematical biology look like? • Where would a mathematical biology program live? In a math department? A biology department? Separate from both? JMM New Orleans 9 January 2011 Sunday, January 9, 2011 3
  • 4. JMM New Orleans 9 January 2011 Sunday, January 9, 2011 4
  • 5. JMM New Orleans 9 January 2011 Sunday, January 9, 2011 5
  • 6. JMM New Orleans 9 January 2011 Sunday, January 9, 2011 6
  • 7. JMM New Orleans 9 January 2011 Sunday, January 9, 2011 7
  • 8. JMM New Orleans 9 January 2011 Sunday, January 9, 2011 8
  • 9. ‘Convergent’ teamwork is going to be a defining characteristic of 21st century science and mathematics. It can’t be taught through a series of lectures. It can’t be taught from a textbook or by reading a journal paper. It can’t be taught in a course for a (single) major. The above activities can motivate students and prepare them to learn to be ‘convergent’ JMM New Orleans 9 January 2011 Sunday, January 9, 2011 9
  • 10. It can be taught... • Our experience provides strong evidence that proper hands-on undergraduate research (or research-like) projects can train undergraduates to be ‘convergent’ • Essential characteristics: • it’s a real research project to the mentors • mentors from different disciplines • undergraduates from different disciplines • long-term immersion • students have sense of significant ownership JMM New Orleans 9 January 2011 Sunday, January 9, 2011 10
  • 11. At Truman... • We’ve been building and revising an interdisciplinary training program in mathematics and biology • Bridging the epistemological gap between mathematics and biology. • NSF funded: UBM program (Interdisciplinary Training for Undergraduates in Biology and Mathematics) in 2003, 2004, and 2009 These allowed us to make mistakes so that others wouldn’t have to. JMM New Orleans 9 January 2011 Sunday, January 9, 2011 11
  • 12. Truman’s Program “We are not trying to turn mathematics majors into biology majors, not are we trying to turn biology majors into mathematics majors. Rather, we are trying to bring both together at the intersection of the life and mathematical sciences to train them to work across disciplinary boundaries.” JMM New Orleans 9 January 2011 Sunday, January 9, 2011 12
  • 13. Why, then? • Pre-Bio2010 selfishness! • We had math faculty who wanted to re-engage in research, learn about mentoring undergraduates; open-minded biologists • Students (in CS) were ahead of us, learning bioinformatics • Had some limited internal support: • Truman had a culture (outside the math department) that valued undergraduate research • Summer research grants for students JMM New Orleans 9 January 2011 Sunday, January 9, 2011 13
  • 14. Truman’s Program • Our ‘program’ grew out of our undergraduate research program, conversations with others in our community • HHMI, SMB, MAA BIOSIGMAA, BioQUEST, MAA PREP, NIMBioS, MBI, NSF UBM PI meetings, CUR, NCUR • We have an interdisciplinary minor in mathematical biology • The minor requires a high-quality, interdisciplinary research experience (on- or off-campus) JMM New Orleans 9 January 2011 Sunday, January 9, 2011 14
  • 15. Why, now? • Having been institutionalized (curriculum), we have internal and external pressures to continue to succeed • Truman still values undergraduate research (even in the mathematics department) • Faculty are getting results (publications, grants) • Contributing to national need for ‘convergent’ or interdisciplinary scientists and mathematicians • Desire to broaden participation in science and mathematics undergraduate degree programs JMM New Orleans 9 January 2011 Sunday, January 9, 2011 15
  • 16. Looking back... • The scope of what we have now would not be possible without the UBM grants • The essence of what we are doing could continue without external funding *but not without internal funding) • What we are doing, others can do. JMM New Orleans 9 January 2011 Sunday, January 9, 2011 16
  • 17. There’s no STEM without an M • Last week, the House and Senate reauthorized the America COMPETES act • The America COMPETES Act is a response to ‘Rising Above the Gathering Storm’ report • The ‘Rising Above the Gathering Storm’ report communicates the reasons America needs to increase its production of STEM professionals • As a result, we have many ‘STEM Talent Expansion’ programs fromt he NIH, NSF, etc. JMM New Orleans 9 January 2011 Sunday, January 9, 2011 17
  • 18. There’s no STEM without an M • Preparing ‘convergent’ scientists is an aspect of this (scientists for the 21st century) • This can’t happen without involvement from the mathematics community. • What our small community is learning about how to collaborate with biologists can be (and should be) applied to working with other disciplines and multi- disciplinary teams. JMM New Orleans 9 January 2011 Sunday, January 9, 2011 18
  • 19. Minor’s Outcomes • Data Acquisition • Modeling • Computation • Statistics • Research JMM New Orleans 9 January 2011 Sunday, January 9, 2011 19
  • 20. Requirements • Demonstrate proficiencies in each category (though research, courses) • Earn 15+ credits doing so (must take Intro to MathBio course) • Attend MathBio Seminar • Participate in two half-semester program workshops/seminars JMM New Orleans 9 January 2011 Sunday, January 9, 2011 20
  • 21. http://mathbio.truman.edu This material is based upon work supported by the National Science Foundation under NSF UBM #0337769, #0436348, and #0926737. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation. JMM New Orleans 9 January 2011 Sunday, January 9, 2011 21