This document summarizes research on using the bacterium strain EB92-1 for biological control of Pierce's disease in grapes. Tests were conducted on grape genotypes in different locations and at various plant growth stages. Results showed that EB92-1 was effective against Pierce's disease in Vitis vinifera cultivars, V. aestivalis, and American hybrids in Florida. Treatment of mature grapevines did not reduce new Pierce's disease cases in the first year but provided some benefit in subsequent years. Biological control was also effective in transplants tested in Florida, Georgia, and South Carolina. Methods of propagating cuttings infected with EB92-1 provided inconsistent control depending on the grape variety. Greenhouse tests found that EB