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Impact of depression on
healthcare expenses
DISCLAIMER
Cost finding can be affected by the following:
◦ Costing perspective (provider vs societal vs consumer)
◦ Type of therapist (doctoral vs master’s vs professional)
◦ Public or private setting
◦ Duration of intervention
◦ Overhead rate applied
How does this relate to
health economics?
PRODUCTIVITY
LARGE MEDICAL EXPENDITURE
RISING MEDICAL EXPENSE
Analysis of...
No Treatment
Costs associated with:
Direct
Suicide
Workplace
Large gap in the literature
Pharmacological
Treatment
Choice of drug varies by study
Variance in measurement
across studies
Cognitive Behavior
Therapy
Variance in measurement
across studies
Inconsistency of salaries of
therapists
No treatment
Direct Costs
1990s ≈ $12 billion
2000 ≈ $26 billion
2005 ≈ $77.5 billion
2010 ≈ $98.9 billion
Workplace Costs
Presenteeism vs Absenteeism
Equivalent of ≈ 32
incremental workdays lost
Suicide-related
Costs
Suicide rate:
14.2 per 100,000 in 2005
15.9 per 100,000 in 2010
50% attributable to
depression
Pharmacological Treatment
Effectiveness
Cost vs Impact on daily life
QALYs
To be determined…
Comparison with…
Cognitive Therapy & No
Treatment
Cognitive therapy treatment
Effectiveness
Cost vs Impact on life
QALYs
To be determined…
Compared with…
Medication
Discussion of findings
Pro’s & con’s
of review
PRO CON
Research is evolving Comorbidities
Gaps being addressed Inconsistency in literature
Cost of treatment outweighed by
savings
Unable to find a standard way to
measure QALYs
Every literature review has valley’s
and mountains
Wrap Up
Bosmans, J. E., van Schaik, D. J., de Bruijne, M. C., van Hout, H. P., van Marwijk, H. W., van Tulder, M. W., & Stalman, W.
A. (2008). Are psychological treatments for depression in primary care cost-effective? J Ment Health Policy Econ,
11(1), 3-15.
Byford, S. S. Impact of treatment success on health service use and cost in depression: longitudinal database
analysis. PharmacoEconomics, 29(2), 157-170. doi:10.2165/11537360-000000000-00000
Cocker, F. F. (2014). Depression in working adults: comparing the costs and health outcomes of working when ill.
PloS one, 9(9), e105430. doi:10.1371/journal.pone.0105430
Donohue, J. M. J. M. (2007). Reducing the societal burden of depression: a review of economic costs, quality of care
and effects of treatment. PharmacoEconomics, 25(1), 7-24.
Imel, Z. E., Malterer, M. B., McKay, K. M., & Wampold, B. E. (2008). A meta-analysis of psychotherapy and medication
in unipolar depression and dysthymia. Journal of affective disorders, 110(3), 197-206.
doi:http://dx.doi.org/10.1016/j.jad.2008.03.018
Sava, F. A. F. A. Cost-effectiveness and cost-utility of cognitive therapy, rational emotive behavioral therapy, and
fluoxetine (Prozac) in treating depression: a randomized clinical trial. Journal of Clinical Psychology, 65(1), 36-52.
doi:10.1002/jclp.20550
Serrano-Blanco, A., Gabarron, E., Garcia-Bayo, I., Soler-Vila, M., Carames, E., Penarrubia-Maria, M. T., . . . Depressio
en Atencio Primaria de Gava, G. (2006). Effectiveness and cost-effectiveness of antidepressant treatment in
primary health care: a six-month randomised study comparing fluoxetine to imipramine. J Affect Disord, 91(2-3),
153-163. doi:10.1016/j.jad.2005.11.014
Wade, A. G. A. G. A review of the costs associated with depression and treatment noncompliance: the potential
benefits of online support. International clinical psychopharmacology, 25(5), 288-296.
Watkins, K. E. K. E. The cost-effectiveness of depression treatment for co-occurring disorders: a clinical trial.
Journal of substance abuse treatment, 46(2), 128-133. doi:10.1016/j.jsat.2013.08.006
Wells, K. B. M. D. M. P. H., Schoenbaum, M. P., Duan, N. P., Miranda, J. P., Tang, L. P., & Sherbourne, C. P. (2007). Cost-
Effectiveness of Quality Improvement Programs for Patients With Subthreshold Depression or Depressive
Disorder. Psychiatric Services, 58(10), 1269-1278. Retrieved from http://www.library.drexel.edu/cgi-
bin/r.cgi/login?url=http://search.proquest.com/docview/213079352?accountid=10559
http://ur9ep9bn4s.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-
8&rfr_id=info:sid/ProQ%3Anursing&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Psychia
tric+Services&rft.atitle=Cost-
Effectiveness+of+Quality+Improvement+Programs+for+Patients+With+Subthreshold+Depression+or+Depressive
+Disorder&rft.au=Wells%2C+Kenneth+B%2C+MD%2C+MPH%3BSchoenbaum%2C+Michael%2C+PhD%3BDuan
%2C+Naihua%2C+PhD%3BMiranda%2C+Jeanne%2C+PhD%3BTang%2C+Lingqi%2C+PhD%3BSherbourne%2C+
Cathy%2C+PhD&rft.aulast=Wells&rft.aufirst=Kenneth&rft.date=2007-10-
01&rft.volume=58&rft.issue=10&rft.spage=1269&rft.isbn=&rft.btitle=&rft.title=Psychiatric+Services&rft.issn=10
752730&rft_id=info:doi/

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Impact of depression on healthcare expenses

  • 1. Impact of depression on healthcare expenses
  • 2. DISCLAIMER Cost finding can be affected by the following: ◦ Costing perspective (provider vs societal vs consumer) ◦ Type of therapist (doctoral vs master’s vs professional) ◦ Public or private setting ◦ Duration of intervention ◦ Overhead rate applied
  • 3. How does this relate to health economics?
  • 7.
  • 8. Analysis of... No Treatment Costs associated with: Direct Suicide Workplace Large gap in the literature Pharmacological Treatment Choice of drug varies by study Variance in measurement across studies Cognitive Behavior Therapy Variance in measurement across studies Inconsistency of salaries of therapists
  • 9. No treatment Direct Costs 1990s ≈ $12 billion 2000 ≈ $26 billion 2005 ≈ $77.5 billion 2010 ≈ $98.9 billion Workplace Costs Presenteeism vs Absenteeism Equivalent of ≈ 32 incremental workdays lost Suicide-related Costs Suicide rate: 14.2 per 100,000 in 2005 15.9 per 100,000 in 2010 50% attributable to depression
  • 10. Pharmacological Treatment Effectiveness Cost vs Impact on daily life QALYs To be determined… Comparison with… Cognitive Therapy & No Treatment
  • 11. Cognitive therapy treatment Effectiveness Cost vs Impact on life QALYs To be determined… Compared with… Medication
  • 13. Pro’s & con’s of review PRO CON Research is evolving Comorbidities Gaps being addressed Inconsistency in literature Cost of treatment outweighed by savings Unable to find a standard way to measure QALYs Every literature review has valley’s and mountains
  • 15. Bosmans, J. E., van Schaik, D. J., de Bruijne, M. C., van Hout, H. P., van Marwijk, H. W., van Tulder, M. W., & Stalman, W. A. (2008). Are psychological treatments for depression in primary care cost-effective? J Ment Health Policy Econ, 11(1), 3-15. Byford, S. S. Impact of treatment success on health service use and cost in depression: longitudinal database analysis. PharmacoEconomics, 29(2), 157-170. doi:10.2165/11537360-000000000-00000 Cocker, F. F. (2014). Depression in working adults: comparing the costs and health outcomes of working when ill. PloS one, 9(9), e105430. doi:10.1371/journal.pone.0105430 Donohue, J. M. J. M. (2007). Reducing the societal burden of depression: a review of economic costs, quality of care and effects of treatment. PharmacoEconomics, 25(1), 7-24. Imel, Z. E., Malterer, M. B., McKay, K. M., & Wampold, B. E. (2008). A meta-analysis of psychotherapy and medication in unipolar depression and dysthymia. Journal of affective disorders, 110(3), 197-206. doi:http://dx.doi.org/10.1016/j.jad.2008.03.018 Sava, F. A. F. A. Cost-effectiveness and cost-utility of cognitive therapy, rational emotive behavioral therapy, and fluoxetine (Prozac) in treating depression: a randomized clinical trial. Journal of Clinical Psychology, 65(1), 36-52. doi:10.1002/jclp.20550
  • 16. Serrano-Blanco, A., Gabarron, E., Garcia-Bayo, I., Soler-Vila, M., Carames, E., Penarrubia-Maria, M. T., . . . Depressio en Atencio Primaria de Gava, G. (2006). Effectiveness and cost-effectiveness of antidepressant treatment in primary health care: a six-month randomised study comparing fluoxetine to imipramine. J Affect Disord, 91(2-3), 153-163. doi:10.1016/j.jad.2005.11.014 Wade, A. G. A. G. A review of the costs associated with depression and treatment noncompliance: the potential benefits of online support. International clinical psychopharmacology, 25(5), 288-296. Watkins, K. E. K. E. The cost-effectiveness of depression treatment for co-occurring disorders: a clinical trial. Journal of substance abuse treatment, 46(2), 128-133. doi:10.1016/j.jsat.2013.08.006 Wells, K. B. M. D. M. P. H., Schoenbaum, M. P., Duan, N. P., Miranda, J. P., Tang, L. P., & Sherbourne, C. P. (2007). Cost- Effectiveness of Quality Improvement Programs for Patients With Subthreshold Depression or Depressive Disorder. Psychiatric Services, 58(10), 1269-1278. Retrieved from http://www.library.drexel.edu/cgi- bin/r.cgi/login?url=http://search.proquest.com/docview/213079352?accountid=10559 http://ur9ep9bn4s.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF- 8&rfr_id=info:sid/ProQ%3Anursing&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Psychia tric+Services&rft.atitle=Cost- Effectiveness+of+Quality+Improvement+Programs+for+Patients+With+Subthreshold+Depression+or+Depressive +Disorder&rft.au=Wells%2C+Kenneth+B%2C+MD%2C+MPH%3BSchoenbaum%2C+Michael%2C+PhD%3BDuan %2C+Naihua%2C+PhD%3BMiranda%2C+Jeanne%2C+PhD%3BTang%2C+Lingqi%2C+PhD%3BSherbourne%2C+ Cathy%2C+PhD&rft.aulast=Wells&rft.aufirst=Kenneth&rft.date=2007-10- 01&rft.volume=58&rft.issue=10&rft.spage=1269&rft.isbn=&rft.btitle=&rft.title=Psychiatric+Services&rft.issn=10 752730&rft_id=info:doi/

Editor's Notes

  1. Presenteeism is being present at work and not working to your full capability Individuals with depression are estimated to work at 70% of their full capability Equivalent to 2.3 days of being absent from work a month NOTED: due to the evolving nature of how companies are run, tele-working and the affect depression has on the venture has yet to be studied
  2. High prevalence means depression & anxiety are expensive to treat on a national scale Most of which is not the result of depression treatment costs MDD direct costs account for 12-15% of the burden 21.6 billion in 2005 27.7 billion in 2010
  3. American population is currently at 318.9 million people Estimated that 16% of American's at some point in their life will experience an episode of major depressive disorder Simply put, 51.024.00 will be affected at some point in their life
  4. Direct costs = cost of delivering the intervention Primary and community care (face to face consultations, prescribed medication, phone consultations) Hospital care (inpatient stays, outpatient appointments, ER visits) Indirect costs: medication, private & alternative therapies, loss of wages, time off work, travel time to appointments Suicide costs 9.4 billion in 2005 rose to 9.7 billion in 2010 Presenteeism costs = 64.7 billion in 2005 and 78.7 billion in 2010 Absenteeism costs = 21.5 billion in 2005 and 23.3 billion in 2010
  5. Cost of wasted medication is estimated to exceed $1 billion a year Few published records of this data Reading in international clinical psychopharmacology said “a reduction in the number of disability absences was equivalent to a saving of $187 per patient per year”