SlideShare a Scribd company logo
Theme: Therapeutics –
evolving and growing sector

Location: UCC,
Western Gateway Building, Cork
Date: Tuesday15th February 2011



                                  © DOLMEN 2010
Sean McNulty, MD
           Dolmen / INNOVATOR is a leading
           consultancy providing innovation management
           and design services to our clients in diverse
           markets.
WHO I AM




                                                      © DOLMEN 2010
SPE AKERs
            Mark Ledwidge, PhD
            Founder & VP Strategy, Solvotrin
            Therapeutics Ltd.


            Christian Stafford, PhD
            Senior Commercialisation Specialist,
            Lifescience & Food Commercialisation
            Group ( EI Bio)
            Enterprise Ireland



                                               © DOLMEN 2010
a Generation 1. Ideas:
Team Ide                Idea gathering
                        Group Ideas
                     2. Develop Opportunities:
                        Map Opportunities
                        Select Opportunities
                        Share Opportunities
                     3. Business Feasibility:
                        Develop the Business
                          potential
                        Rate your business
                          feasibility!
                                          © DOLMEN 2010
TEAM 1

IDENTIFY CELLULAR ASSETS


                           © DOLMEN 2010
se ts
                     aseting
                la-rmark
          ce llu >                          •Cellular arrays
     tifyity ->
IdenUnivers •Primary Cells                  •Royalty
             •Toxicology                          •IP legal
             •Stream-lined decision time    •Cost of patents and cell lines
             •Commercialisation focus       •Cell banks
                                                  •Devils advocate
             •Preclinical                         •Personalised med
                  •Pre Ind
             •Deposit bank of information
             •Identification process
                                            Ger Fitz (Micro)
             •Value
             •Broadband in a box            Brand
                   •Product for sale
             •Brand as commodity            Benefits:
             •Linking into catelogues       • University revenue generation
                                            Co-cost of entry:
             •Marketing commodities         • Centralising through single conduit.
             •Cell lines                    •International access.
                                                                                     © DOLMEN 2010
ity
        tun
      or ng
    pp pi                           TITLE: SILVERCELL
 . O ap
2 M
             The ideas              Describe the solution -           Customer
• Existing certified storage GLP    concept/system                    Identify what is the target market?
                                                                      Who is the customers? End users? Other
• Licensed by the IMB                                                 beneficiaries?

• Facilitate the international                                        - Toxicologists
trade of cells and tissues.                                           - Pharma
• Direct link with Pharmacies.                                        - Dry discon.
• Create revenue for
                                    What are the benefits?
Univeristies
                                    -University revenue generation.
• Make research sustainable
                                    Cost efficient centralised
• In future Industry will require
                                    process. International single
safety and ….. On human tissue
                                    brand.
and cells.
• Toxicity testing                                                                                 © DOLMEN 2010
TEAM 2

LINKSYN IN 51ST STATE


                        © DOLMEN 2010
n        g
             rtunit y M ap p i
2. Oppo                             TITLE: LINKSYN IN 51st STATE
           The ideas                Describe the solution -     Customer
                                    concept/system              Identify what is the target market?
• PROFILE TARGET MATCH                                          Who is the customers? End users? Other
                                                                beneficiaries?
• NETWORK                           - HOW TO LEVERAGE LOCAL
                                                                -MNCs + SMEs.
• ‘Irish Mafia’ Techlink. Team of   FOOTPRINT BY DEVELOPING

experts                             LOCAL NETWORKS.

• BARE PIPELINE
• R&D
                                    What are the benefits?

• NICHE EXPERTISE                   - FUNDING COLLABORATION.
• Id: decision makers, HQ           MARKET ACCESS. JOBS. TAX.
contacts



                                                                                             © DOLMEN 2010
ig
                           a rma + b
              se of big Ph print in
    anced u
                                               • Unused IP
                              t
E nh              d tech foo
        + big me efit of SMEs.
                                               • License money
  food              en
           nd for b
                                               • What do SMEs need?
     Irela                                     • Money market resources
                                               • How not to get swallowed?
                                               • Contacts to HQ
                                               •Path to market
    • How to leverage local footprint.
    • Linksyn in the 51st State
                                               • Customer- an individual or a group within a …
    •Customer decision makers.
                                               • Value proposition

    • Profile multinationals                   • Research Vs Development

    • Match company profile to your offering   • Niche expertise

    • Incentives                               • Networks: Bio, Pharma…
                                               •What is in it for local MGR?
    • services supplied?
                                               • Irish Mafia
    •Broaden pipeline



                                                                                           © DOLMEN 2010
TEAM 3

SPIN DOCTORS


               © DOLMEN 2010
nity M apping
2. Opportu                      TITLE: SPIN DOCTORS
            The ideas          Describe the solution -             Customer
                               concept/system                      Identify what is the target market?
  • €5million fund                                                 Who is the customers? End users? Other
                                                                   beneficiaries?
  • 20 in 5                    Experts in therapeutics will lead
                                                                   • PI Institution
  • market driven evaluation   start-ups to success by following
                                                                   • VC
  • Early partner scouting     the money from seed to
                                                                   • Big Pharma Foundations
  •Follow the money            $millions to exit.

  • Business Partners           What are the benefits?
  •Mentors                     -Industry experts. Seed funding.
  • R&D and production in      Right location. Money.
  Ireland
  • HQ in USA
  • Experts
                                                                                                © DOLMEN 2010
R
          O DEL FO P
      EW M TART-U
1. A N UTIC S                                          2. P
                                                               ICK
TH ERAPE                                                           AND
                                                                       ‘LAN
                                                                    PAR D’ TH
                                                                        TNE   E RI
                                                                            R      GHT
    • too much focus on start-up?            • For Pharma

    •Startup US license?                     • Their needs, market size

    • When is the right time?                • Data compatible with product roadmap

    • What is a good idea?                   • sales force-IP/patient

    • Market size >€1b                       •Niche

    • People-lack of comm skills- sales/mk   • Reg status

    • No VC infastructure                    •For startup

    • €5m fund 2015                          •Source of funding

    • Technology evaluation                  • Routes to market

    • Follow the money                       • Business Plan

    • Market driver- R&D!!!                  • Sale or partnership, (exit), timing

    •Scouting Partners early                 • Value of business/technology
                                             •Reg status

                                                                                      © DOLMEN 2010
TEAM 4

NCTFC


         © DOLMEN 2010
nity M apping
2. Opportu             TITLE: NCTFC                          National Clinical Trials Funding Corp



      The ideas       Describe the solution -                      Customer
                      concept/system                               Identify what is the target market?
                                                                   Who is the customers? End users? Other
                                                                   beneficiaries?
                      A new funding structure for
                                                                   • Pis
                      Clinical trials in Ireland.
                                                                   •Pharma
                                                                   •Device

                       What are the benefits?
                      -Deliver Phase II trials in Ireland.
                      - Funding streams
                      -Health system
                      -Grow indigenous companies

                                                                                                © DOLMEN 2010
o
                  ment (t
 Make   develop cient
            ore effi
                                        •I.T system

phase II) m                             •Data management
             • Specialist areas
                                        •Pharma
                •Sponsor (Directives)   •Device

                •National Structure
                •€250million
                •HSE
                •2% budget

                •Regulatory Ethics

                •CRO

                •C.R.C’s
                •Research nurses
                •Revenue Streams
                •Funding
                     •€5-10million
                                                           © DOLMEN 2010
resentations
       P
TEAM
  Presentation of
  value propositions
  for selected
  opportunities.




                        © DOLMEN 2010
t happe ns next
Wha
        • Complete and return the participant follow up
          sheet to your EI Regional Development Executive
        • Join the IDEAGEN LinkedIn group
          http://www.linkedin.com/groups?gid=2649046&trk=hb_side_g

          Keep up to date on latest from IDEAGEN by
        • Following on Twitter
               http://twitter.com/ideagen
          •Becoming a fan on Facebook
          http://www.facebook.com/pages/Ideagen/134045788401



                                                               © DOLMEN 2010
T he End


           Thank you

           Sean McNulty
           smcnulty@dolmen.ie




                                © DOLMEN 2010

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Ideagen Cork report

  • 1. Theme: Therapeutics – evolving and growing sector Location: UCC, Western Gateway Building, Cork Date: Tuesday15th February 2011 © DOLMEN 2010
  • 2. Sean McNulty, MD Dolmen / INNOVATOR is a leading consultancy providing innovation management and design services to our clients in diverse markets. WHO I AM © DOLMEN 2010
  • 3. SPE AKERs Mark Ledwidge, PhD Founder & VP Strategy, Solvotrin Therapeutics Ltd. Christian Stafford, PhD Senior Commercialisation Specialist, Lifescience & Food Commercialisation Group ( EI Bio) Enterprise Ireland © DOLMEN 2010
  • 4. a Generation 1. Ideas: Team Ide Idea gathering Group Ideas 2. Develop Opportunities: Map Opportunities Select Opportunities Share Opportunities 3. Business Feasibility: Develop the Business potential Rate your business feasibility! © DOLMEN 2010
  • 5. TEAM 1 IDENTIFY CELLULAR ASSETS © DOLMEN 2010
  • 6. se ts aseting la-rmark ce llu > •Cellular arrays tifyity -> IdenUnivers •Primary Cells •Royalty •Toxicology •IP legal •Stream-lined decision time •Cost of patents and cell lines •Commercialisation focus •Cell banks •Devils advocate •Preclinical •Personalised med •Pre Ind •Deposit bank of information •Identification process Ger Fitz (Micro) •Value •Broadband in a box Brand •Product for sale •Brand as commodity Benefits: •Linking into catelogues • University revenue generation Co-cost of entry: •Marketing commodities • Centralising through single conduit. •Cell lines •International access. © DOLMEN 2010
  • 7. ity tun or ng pp pi TITLE: SILVERCELL . O ap 2 M The ideas Describe the solution - Customer • Existing certified storage GLP concept/system Identify what is the target market? Who is the customers? End users? Other • Licensed by the IMB beneficiaries? • Facilitate the international - Toxicologists trade of cells and tissues. - Pharma • Direct link with Pharmacies. - Dry discon. • Create revenue for What are the benefits? Univeristies -University revenue generation. • Make research sustainable Cost efficient centralised • In future Industry will require process. International single safety and ….. On human tissue brand. and cells. • Toxicity testing © DOLMEN 2010
  • 8. TEAM 2 LINKSYN IN 51ST STATE © DOLMEN 2010
  • 9. n g rtunit y M ap p i 2. Oppo TITLE: LINKSYN IN 51st STATE The ideas Describe the solution - Customer concept/system Identify what is the target market? • PROFILE TARGET MATCH Who is the customers? End users? Other beneficiaries? • NETWORK - HOW TO LEVERAGE LOCAL -MNCs + SMEs. • ‘Irish Mafia’ Techlink. Team of FOOTPRINT BY DEVELOPING experts LOCAL NETWORKS. • BARE PIPELINE • R&D What are the benefits? • NICHE EXPERTISE - FUNDING COLLABORATION. • Id: decision makers, HQ MARKET ACCESS. JOBS. TAX. contacts © DOLMEN 2010
  • 10. ig a rma + b se of big Ph print in anced u • Unused IP t E nh d tech foo + big me efit of SMEs. • License money food en nd for b • What do SMEs need? Irela • Money market resources • How not to get swallowed? • Contacts to HQ •Path to market • How to leverage local footprint. • Linksyn in the 51st State • Customer- an individual or a group within a … •Customer decision makers. • Value proposition • Profile multinationals • Research Vs Development • Match company profile to your offering • Niche expertise • Incentives • Networks: Bio, Pharma… •What is in it for local MGR? • services supplied? • Irish Mafia •Broaden pipeline © DOLMEN 2010
  • 11. TEAM 3 SPIN DOCTORS © DOLMEN 2010
  • 12. nity M apping 2. Opportu TITLE: SPIN DOCTORS The ideas Describe the solution - Customer concept/system Identify what is the target market? • €5million fund Who is the customers? End users? Other beneficiaries? • 20 in 5 Experts in therapeutics will lead • PI Institution • market driven evaluation start-ups to success by following • VC • Early partner scouting the money from seed to • Big Pharma Foundations •Follow the money $millions to exit. • Business Partners What are the benefits? •Mentors -Industry experts. Seed funding. • R&D and production in Right location. Money. Ireland • HQ in USA • Experts © DOLMEN 2010
  • 13. R O DEL FO P EW M TART-U 1. A N UTIC S 2. P ICK TH ERAPE AND ‘LAN PAR D’ TH TNE E RI R GHT • too much focus on start-up? • For Pharma •Startup US license? • Their needs, market size • When is the right time? • Data compatible with product roadmap • What is a good idea? • sales force-IP/patient • Market size >€1b •Niche • People-lack of comm skills- sales/mk • Reg status • No VC infastructure •For startup • €5m fund 2015 •Source of funding • Technology evaluation • Routes to market • Follow the money • Business Plan • Market driver- R&D!!! • Sale or partnership, (exit), timing •Scouting Partners early • Value of business/technology •Reg status © DOLMEN 2010
  • 14. TEAM 4 NCTFC © DOLMEN 2010
  • 15. nity M apping 2. Opportu TITLE: NCTFC National Clinical Trials Funding Corp The ideas Describe the solution - Customer concept/system Identify what is the target market? Who is the customers? End users? Other beneficiaries? A new funding structure for • Pis Clinical trials in Ireland. •Pharma •Device What are the benefits? -Deliver Phase II trials in Ireland. - Funding streams -Health system -Grow indigenous companies © DOLMEN 2010
  • 16. o ment (t Make develop cient ore effi •I.T system phase II) m •Data management • Specialist areas •Pharma •Sponsor (Directives) •Device •National Structure •€250million •HSE •2% budget •Regulatory Ethics •CRO •C.R.C’s •Research nurses •Revenue Streams •Funding •€5-10million © DOLMEN 2010
  • 17. resentations P TEAM Presentation of value propositions for selected opportunities. © DOLMEN 2010
  • 18. t happe ns next Wha • Complete and return the participant follow up sheet to your EI Regional Development Executive • Join the IDEAGEN LinkedIn group http://www.linkedin.com/groups?gid=2649046&trk=hb_side_g Keep up to date on latest from IDEAGEN by • Following on Twitter http://twitter.com/ideagen •Becoming a fan on Facebook http://www.facebook.com/pages/Ideagen/134045788401 © DOLMEN 2010
  • 19. T he End Thank you Sean McNulty smcnulty@dolmen.ie © DOLMEN 2010