Aspectos positivos e gargalos para a inovação - preços das novas tecnologias ...Empreender Saúde
********* Temas a discutir
Aspectos positivos da Saúde no Brasil
Gargalos
Incorporação de novas tecnologias
Registro de preços - CEMED
Tendências do mercado e os seus impactos
Sugestões para melhoramento
************ Aspectos positivos
Ampla cobertura assistencial (SUS + Privado)
Tecnologia de ponta disponível em vários hospitais públicos e privados
Estrito controle sanitário (ANVISA)
********* Gargalos
Baixo nível de atendimento em rede publica, SUS e planos/hospitais privados menores
Alto custo do Brasil
Processos governamentais burocráticos e demorados:
Registro de novos produtos (ANVISA)
Processo de aprovação de pesquisas e de incorporação de novas tecnologias no SUS
Metodologia de aprovação de registro de preços de medicamentos (CMED)
Baixo investimento (ou mal aproveitamento) do Governo – Reembolsos SUS desfasados
******* Incorporação de novas tecnologias
No SUS – CONITEC
Leva em consideração aspectos como eficácia, acurácia, efetividade e segurança, além da avaliação econômica dos benefícios e dos custos em relação as tecnologias já existentes
Requer registro prévio na ANVISA – Para medicamentos precisa preços registrados na CEMED
No âmbito privado
Requer registro prévio na ANVISA
Para medicamentos precisa preços registrados na CEMED
****** Resolução CEMED Nro. 2, 2004
Critérios para apuração de preços de novos medicamentos a serem lançados no mercado
Novas apresentações não podem ter preços superiores aos já praticados no mercado para a mesma sustância ativa
Novos medicamentos, apos analise comparativa de eficácia terapêutica, terão preços limitados pelo custo de tratamento das opções terapêuticas disponíveis e pelo menor preço praticado para o mesmo produto no mercado internacional
Medicamentos inovadores – Molécula que seja objeto de patente no pais e traga ganho para o tratamento – Preço não pode ser superior ao menor preço praticado em Austrália, Canada, Estados Unidos, Espanha, Grécia, Portugal, Franca, Itália e Nova Zelândia
PRECOS NAO PODEM SER SUPERIORES AOS PRATICADOS EM OUTROS PAISES COM MERCADOS DE MENOR CUSTO E DINAMICAS DIFERENTES
******** Novas tecnologias tem dificuldade em obter preços adequados
Preços autorizados pela CEMED:
- Não podem ser superiores aos dos outros países com estruturas de custo muito diferentes (infraestrutura, impostos, etc.)
- Preços registrados em reais não podem ser ajustados pela variação cambial
Não podem ser superiores as antigas tecnologias já existentes no Brasil
Em alguns casos as tecnologias antigas tem preços registrados (reembolso) muito superiores aos das novas!
Registrados previamente a resolução da CMED
Aspectos positivos e gargalos para a inovação - preços das novas tecnologias ...Empreender Saúde
********* Temas a discutir
Aspectos positivos da Saúde no Brasil
Gargalos
Incorporação de novas tecnologias
Registro de preços - CEMED
Tendências do mercado e os seus impactos
Sugestões para melhoramento
************ Aspectos positivos
Ampla cobertura assistencial (SUS + Privado)
Tecnologia de ponta disponível em vários hospitais públicos e privados
Estrito controle sanitário (ANVISA)
********* Gargalos
Baixo nível de atendimento em rede publica, SUS e planos/hospitais privados menores
Alto custo do Brasil
Processos governamentais burocráticos e demorados:
Registro de novos produtos (ANVISA)
Processo de aprovação de pesquisas e de incorporação de novas tecnologias no SUS
Metodologia de aprovação de registro de preços de medicamentos (CMED)
Baixo investimento (ou mal aproveitamento) do Governo – Reembolsos SUS desfasados
******* Incorporação de novas tecnologias
No SUS – CONITEC
Leva em consideração aspectos como eficácia, acurácia, efetividade e segurança, além da avaliação econômica dos benefícios e dos custos em relação as tecnologias já existentes
Requer registro prévio na ANVISA – Para medicamentos precisa preços registrados na CEMED
No âmbito privado
Requer registro prévio na ANVISA
Para medicamentos precisa preços registrados na CEMED
****** Resolução CEMED Nro. 2, 2004
Critérios para apuração de preços de novos medicamentos a serem lançados no mercado
Novas apresentações não podem ter preços superiores aos já praticados no mercado para a mesma sustância ativa
Novos medicamentos, apos analise comparativa de eficácia terapêutica, terão preços limitados pelo custo de tratamento das opções terapêuticas disponíveis e pelo menor preço praticado para o mesmo produto no mercado internacional
Medicamentos inovadores – Molécula que seja objeto de patente no pais e traga ganho para o tratamento – Preço não pode ser superior ao menor preço praticado em Austrália, Canada, Estados Unidos, Espanha, Grécia, Portugal, Franca, Itália e Nova Zelândia
PRECOS NAO PODEM SER SUPERIORES AOS PRATICADOS EM OUTROS PAISES COM MERCADOS DE MENOR CUSTO E DINAMICAS DIFERENTES
******** Novas tecnologias tem dificuldade em obter preços adequados
Preços autorizados pela CEMED:
- Não podem ser superiores aos dos outros países com estruturas de custo muito diferentes (infraestrutura, impostos, etc.)
- Preços registrados em reais não podem ser ajustados pela variação cambial
Não podem ser superiores as antigas tecnologias já existentes no Brasil
Em alguns casos as tecnologias antigas tem preços registrados (reembolso) muito superiores aos das novas!
Registrados previamente a resolução da CMED
Aula do prof. Luiz Agner sobre análise quantitativa de dados do Card Sorting. Disciplina de Arquitetura de Informação. Pós em MKT e Design Digital. ESPM, 2009.
AeHIN 28 August, 2014 - Innovation in Healthcare IT Standards: The Path to Bi...Timothy Cook
AeHIN Hour is our network's regular webinar where we feature topics on eHealth, HIS, and Civil Registration and Vital Statistics.
This presentation was from Dr. Luciana Cavalini, PhD. and Timothy Cook, MSc.
Profa. Luciana Tricai Cavalini, MD, PhD.
Luciana is a physician with PhD in Public Health. She is a Professor at the Department of Health Information Technologies, Medical Sciences College, Rio de Janeiro State University, Brazil and Professor at the Department of Epidemiology and Biostatistics, Community Health Institute, Fluminense Federal University, Brazil.
Luciana is also the Coordinator of the Technological Development Unit in Multilevel Healthcare Information Modeling and Coordinator of the Emergent Group in Research and Innovation on Healthcare Information Technologies. br.linkedin.com/pub/luciana-tricai-cavalini/88/8b6/533/en
Timothy Wayne Cook, MSc.
Tim is an Advanced Electronics Technologist with a MSc in Health Informatics.
He is the creator and core developer of the Multilevel Healthcare Information Modeling (MLHIM) specifications and Chief Technology Officer at MedWeb 3.0 (The Semantic Med Web). He also serves as International Collaborator at the National Institute of Science and Technology – Medicine Assisted by Scientific Computing, Brazil. https://www.linkedin.com/in/timothywaynecook
Conheça o Guia rápido do Microsoft Project 2013.
Para conhecer mais sobre a ferramenta ou desejar apresentações converse com um de nossos consultores que iremos agora mesmo em sua empresa e fazemos uma apresentação das novas funcionalidades do Project 2013 contato@webcarioca.com.br
Este artigo faz uma reflexão sobre o surgimento e o desenvolvimento dos jogos eróticos.
Nesse contexto se discute a criação de um gamearte em ambiente virtual tridimensional de conteúdo adulto. CyberSexGame tem por objetivo simular alguns aspectos da vida real e da
comunicação entre humanos, máquinas e outras espécies. Ao enfatizar a produção de
símbolos imagéticos, sonoros e hápticos reais/virtuais construídos colaborativamente,
permitem ao usuário, manter inter-relações afetivas e/ou sexuais com demais pessoas por meio da Internet, em tempo real.
Dr. Luciana Cavalini's presentation at the 6th meeting of the Brazilian Python Community in 2010.
See: http://www.mlhim.org http://gplus.to/MLHIM and http://gplus.to/MLHIMComm for more information about semantic interoperability in healthcare.
#mlhim #semantic_interoperability #health_informatics
Aula do prof. Luiz Agner sobre análise quantitativa de dados do Card Sorting. Disciplina de Arquitetura de Informação. Pós em MKT e Design Digital. ESPM, 2009.
AeHIN 28 August, 2014 - Innovation in Healthcare IT Standards: The Path to Bi...Timothy Cook
AeHIN Hour is our network's regular webinar where we feature topics on eHealth, HIS, and Civil Registration and Vital Statistics.
This presentation was from Dr. Luciana Cavalini, PhD. and Timothy Cook, MSc.
Profa. Luciana Tricai Cavalini, MD, PhD.
Luciana is a physician with PhD in Public Health. She is a Professor at the Department of Health Information Technologies, Medical Sciences College, Rio de Janeiro State University, Brazil and Professor at the Department of Epidemiology and Biostatistics, Community Health Institute, Fluminense Federal University, Brazil.
Luciana is also the Coordinator of the Technological Development Unit in Multilevel Healthcare Information Modeling and Coordinator of the Emergent Group in Research and Innovation on Healthcare Information Technologies. br.linkedin.com/pub/luciana-tricai-cavalini/88/8b6/533/en
Timothy Wayne Cook, MSc.
Tim is an Advanced Electronics Technologist with a MSc in Health Informatics.
He is the creator and core developer of the Multilevel Healthcare Information Modeling (MLHIM) specifications and Chief Technology Officer at MedWeb 3.0 (The Semantic Med Web). He also serves as International Collaborator at the National Institute of Science and Technology – Medicine Assisted by Scientific Computing, Brazil. https://www.linkedin.com/in/timothywaynecook
Conheça o Guia rápido do Microsoft Project 2013.
Para conhecer mais sobre a ferramenta ou desejar apresentações converse com um de nossos consultores que iremos agora mesmo em sua empresa e fazemos uma apresentação das novas funcionalidades do Project 2013 contato@webcarioca.com.br
Este artigo faz uma reflexão sobre o surgimento e o desenvolvimento dos jogos eróticos.
Nesse contexto se discute a criação de um gamearte em ambiente virtual tridimensional de conteúdo adulto. CyberSexGame tem por objetivo simular alguns aspectos da vida real e da
comunicação entre humanos, máquinas e outras espécies. Ao enfatizar a produção de
símbolos imagéticos, sonoros e hápticos reais/virtuais construídos colaborativamente,
permitem ao usuário, manter inter-relações afetivas e/ou sexuais com demais pessoas por meio da Internet, em tempo real.
Dr. Luciana Cavalini's presentation at the 6th meeting of the Brazilian Python Community in 2010.
See: http://www.mlhim.org http://gplus.to/MLHIM and http://gplus.to/MLHIMComm for more information about semantic interoperability in healthcare.
#mlhim #semantic_interoperability #health_informatics
In need of an update, existing healthcare infrastructure has been revamped during COVID-19, while telehealth has become a priority for many organizations.
Tips For A Great Telehealth Patient ExperienceTodd Berner MD
In the face of a global pandemic, healthcare organizations have been forced to adjust their approach to telehealth. Here's how any healthcare professional can remotely connect with their patients.
Staying Productive in the Face of Clinician BurnoutTodd Berner MD
Clinician burnout is driving many to early retirement or to leave the healthcare industry. Hospitals should approach this issue as a long-term investment and plan to support their doctors.
For hospitals and other healthcare facilities, it's important to realize that delivering a great service is more important than ever in the face of consumers comparison shopping.
Though patient portals have enjoyed widespread adoption among healthcare professionals, patients have been much more apathetic. How can organizations listen to patients and make these tools more palatable?
Patient Engagement Is Not One Size Fits AllTodd Berner MD
Patient engagement shouldn't be all about technology. Rather, care providers owe it to their patients to determine the best ways to get them involved in their health and ensure the best outcomes for them.
Patient advocacy is especially important for those living with rare diseases. As the potential to cure some of these conditions rises with the advent of gene therapy, advocacy groups will need to ensure ethical testing and implementation of new solutions.
Todd Berner talks about the growing potential for gene therapy methods to treat rare diseases that previously would have been difficult to effectively address.
Pharmaceutical companies are reevaluating the way they help patients. From better production and distribution of medicine to improvements in patient engagement, the future looks highly dependent on innovative technology and better communication.
Virtual reality has become a popular technology for entertainment in recent years, but it has other applications as well. Learn about how VR can be used to prepare aspiring doctors and surgeons for working with patients.
The CRISPR Controversy—The Debate Over Genetic ManipulationTodd Berner MD
Todd Berner gives a rundown of recent news and developments on CRISPR, a genetic manipulation tool creating a buzz in the scientific community for its potential applications and debatable ownership.
Go Big or Go Home—The Data Boon in HealthcareTodd Berner MD
Big Data has the potential to give us insights into our own physical conditions more than ever before. Read about some of the best applications for this new trend.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
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- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
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CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound