"How Scientific Wellness will Drive The Future of Health" - Nathan Price (Professor, Institute of Systems Biology)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
"Launching a New Industry – Scientific Wellness" - Mia Nease (Head of Commerc...Hyper Wellbeing
"Launching a New Industry – Scientific Wellness" - Mia Nease (Head of Commercial, Arivale)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
"Alliances with Lifestyle Medicine for Wellness as a Service (WaaS)" - Ingrid...Hyper Wellbeing
"Alliances with Lifestyle Medicine for Wellness as a Service (WaaS)" - Ingrid Edshteyn (Associate Exec Director/Founder, ACLM/Valia Lifestyle)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
"Enabling Access to Continuous Metabolic Data for Personalized Nutrition and ...Hyper Wellbeing
"Enabling Access to Continuous Metabolic Data for Personalized Nutrition and Wellbeing" - Ashwin Pushpala (CEO, Sano)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
"Empowering Consumer with Smart Devices and Smart Data for Proactive ‘Health ...Hyper Wellbeing
"Empowering Consumer with Smart Devices and Smart Data for Proactive ‘Health Care’" - Maryam Ziaei (Founder/CEO, iSono Health)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
"Enabling Individual Wellness through Computational Systems Biology, Cloud An...Hyper Wellbeing
"Enabling Individual Wellness through Computational Systems Biology, Cloud Analytics, Wearables, Machine Learning and More" - Riaan Conradie (Co-Founder, LifeQ)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
HXR 2016: Which Comes First: Overeating or Obesity? -Dr. David Ludwig, Boston...HxRefactored
The conventional approach to weight loss, based on the calorie balance model, offers the simple advice, “eat less and move more.” Unfortunately, few people can maintain weight loss over the long term through calorie restriction because the body fights back, with rising hunger and slowing metabolism. An alternative approach to treatment aims to target the underlying driver of weight gain – fat cells overstimulated to hoard too many calories – leading to weight loss with less struggle.
"Bringing Clinically Accurate Data into the Hands of Consumers for the First ...Hyper Wellbeing
"Bringing Clinically Accurate Data into the Hands of Consumers for the First 1000 Days of Life" - Julien Penders (Co-Founder/COO, Bloom Technologies)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
"Launching a New Industry – Scientific Wellness" - Mia Nease (Head of Commerc...Hyper Wellbeing
"Launching a New Industry – Scientific Wellness" - Mia Nease (Head of Commercial, Arivale)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
"Alliances with Lifestyle Medicine for Wellness as a Service (WaaS)" - Ingrid...Hyper Wellbeing
"Alliances with Lifestyle Medicine for Wellness as a Service (WaaS)" - Ingrid Edshteyn (Associate Exec Director/Founder, ACLM/Valia Lifestyle)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
"Enabling Access to Continuous Metabolic Data for Personalized Nutrition and ...Hyper Wellbeing
"Enabling Access to Continuous Metabolic Data for Personalized Nutrition and Wellbeing" - Ashwin Pushpala (CEO, Sano)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
"Empowering Consumer with Smart Devices and Smart Data for Proactive ‘Health ...Hyper Wellbeing
"Empowering Consumer with Smart Devices and Smart Data for Proactive ‘Health Care’" - Maryam Ziaei (Founder/CEO, iSono Health)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
"Enabling Individual Wellness through Computational Systems Biology, Cloud An...Hyper Wellbeing
"Enabling Individual Wellness through Computational Systems Biology, Cloud Analytics, Wearables, Machine Learning and More" - Riaan Conradie (Co-Founder, LifeQ)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
HXR 2016: Which Comes First: Overeating or Obesity? -Dr. David Ludwig, Boston...HxRefactored
The conventional approach to weight loss, based on the calorie balance model, offers the simple advice, “eat less and move more.” Unfortunately, few people can maintain weight loss over the long term through calorie restriction because the body fights back, with rising hunger and slowing metabolism. An alternative approach to treatment aims to target the underlying driver of weight gain – fat cells overstimulated to hoard too many calories – leading to weight loss with less struggle.
"Bringing Clinically Accurate Data into the Hands of Consumers for the First ...Hyper Wellbeing
"Bringing Clinically Accurate Data into the Hands of Consumers for the First 1000 Days of Life" - Julien Penders (Co-Founder/COO, Bloom Technologies)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
Mobile Health at Ochsner: The Apple HealthKit and Epic EMR IntegrationRahlyn Gossen
These slides are from the April 2, 2015 meeting of Health 2.0 New Orleans with special guest Jonathan Wilt, the Assistant Vice President of the Center for Innovation at Ochsner Health System. Jonathan spoke about Ochsner's Health System's integration of Apple HealthKit with the Epic EMR.
Audio is here: http://www.youtube.com/watch?v=UsSKui7m4VY
IoT, Big Data Healthcare Summit Western Canada - Wearables from Lab to Bedsid...Ingunn Grip Fjær
Wearables from Lab to Bedside: The Stanford Wearable Health Lab Story by Matthew Smuck, MD, Chief, Physical Medicine & Rehabilitation, Associate Professor, Orthopaedics, Director, Wearable Health Lab, Stanford University. Presented at the IoT, Big Data Healthcare Summit Western Canada on February 1, 2017.
IoT, Big Data Healthcare Summit Western Canada - Connecting With Technology -...Ingunn Grip Fjær
Connecting With Technology - Where We Are Going? by William L. Clifford, M.D., FCFP, Chief Medical Information Officer at Northern Health BC. Presented at the IoT, Big Data Healthcare Summit Western Canada on February 1, 2017.
12 Gifts of Digital Health: How Futuristic Technologies Changed Healthcare an...Enspektos, LLC
When people talk about how digital technologies will influence health, many assume changes will happen years or decades into the future. Yet, in 2014 a range of digital tech, from Big Data to genomics, gave people the gift of life, knowledge and more. Look back at the year that was in digital health and understand that he future is now.
Presentation by Robin A. Felder, PhD, Professor and Associate Director of Clinical Chemistry and Pathology, former Director of the Medical Automation Research Center and Chair, Medical Automation
AppRx Top Health & Medical Apps for Android. Annual Report
Source: HealthTap, https://www.healthtap.com/top_health_apps_2014
HealthTap is proud to release its first annual report on the top health and medical apps available today. Doctors on HealthTap have independently reviewed tens of thousands of health apps and provided recommendations for the best ones among the 100,000 health and wellness apps available in the iOS and Android app stores today.
By dividing apps into 30 separate categories, AppRx and the HealthTap Annual AppRx Report help users make sense of the vast landscape of health and wellness apps. The independent reviews provided by doctors on HealthTap help both patients and peer doctors learn which apps are medically sound, useful in supporting health or wellness goals, and easy to learn and use. The ratings reveal some surprising recommendations for best apps that might otherwise be missed.
"Continuous Digital Biomarkers from Wearable Devices" - Brandon Ballinger (Co...Hyper Wellbeing
"Continuous Digital Biomarkers from Wearable Devices" - Brandon Ballinger (Co-Founder, Cardiogram)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
"Hacking the Software for Life" - Brad Perkins (Chief Medical Officer, Human ...Hyper Wellbeing
"Hacking the Software for Life" - Brad Perkins (Chief Medical Officer, Human Logevity, Inc.)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
Mobile Health at Ochsner: The Apple HealthKit and Epic EMR IntegrationRahlyn Gossen
These slides are from the April 2, 2015 meeting of Health 2.0 New Orleans with special guest Jonathan Wilt, the Assistant Vice President of the Center for Innovation at Ochsner Health System. Jonathan spoke about Ochsner's Health System's integration of Apple HealthKit with the Epic EMR.
Audio is here: http://www.youtube.com/watch?v=UsSKui7m4VY
IoT, Big Data Healthcare Summit Western Canada - Wearables from Lab to Bedsid...Ingunn Grip Fjær
Wearables from Lab to Bedside: The Stanford Wearable Health Lab Story by Matthew Smuck, MD, Chief, Physical Medicine & Rehabilitation, Associate Professor, Orthopaedics, Director, Wearable Health Lab, Stanford University. Presented at the IoT, Big Data Healthcare Summit Western Canada on February 1, 2017.
IoT, Big Data Healthcare Summit Western Canada - Connecting With Technology -...Ingunn Grip Fjær
Connecting With Technology - Where We Are Going? by William L. Clifford, M.D., FCFP, Chief Medical Information Officer at Northern Health BC. Presented at the IoT, Big Data Healthcare Summit Western Canada on February 1, 2017.
12 Gifts of Digital Health: How Futuristic Technologies Changed Healthcare an...Enspektos, LLC
When people talk about how digital technologies will influence health, many assume changes will happen years or decades into the future. Yet, in 2014 a range of digital tech, from Big Data to genomics, gave people the gift of life, knowledge and more. Look back at the year that was in digital health and understand that he future is now.
Presentation by Robin A. Felder, PhD, Professor and Associate Director of Clinical Chemistry and Pathology, former Director of the Medical Automation Research Center and Chair, Medical Automation
AppRx Top Health & Medical Apps for Android. Annual Report
Source: HealthTap, https://www.healthtap.com/top_health_apps_2014
HealthTap is proud to release its first annual report on the top health and medical apps available today. Doctors on HealthTap have independently reviewed tens of thousands of health apps and provided recommendations for the best ones among the 100,000 health and wellness apps available in the iOS and Android app stores today.
By dividing apps into 30 separate categories, AppRx and the HealthTap Annual AppRx Report help users make sense of the vast landscape of health and wellness apps. The independent reviews provided by doctors on HealthTap help both patients and peer doctors learn which apps are medically sound, useful in supporting health or wellness goals, and easy to learn and use. The ratings reveal some surprising recommendations for best apps that might otherwise be missed.
"Continuous Digital Biomarkers from Wearable Devices" - Brandon Ballinger (Co...Hyper Wellbeing
"Continuous Digital Biomarkers from Wearable Devices" - Brandon Ballinger (Co-Founder, Cardiogram)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
"Hacking the Software for Life" - Brad Perkins (Chief Medical Officer, Human ...Hyper Wellbeing
"Hacking the Software for Life" - Brad Perkins (Chief Medical Officer, Human Logevity, Inc.)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
"Optimizing your Health at Home using your Blood and your Smartphone" - Bob M...Hyper Wellbeing
"Optimizing your Health at Home using your Blood and your Smartphone" - Bob Messerschmidt (CEO, Cor)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
"Future of Consumer Bio-Sensors" - Stanley Yang (CEO, NeuroSky)Hyper Wellbeing
"Future of Consumer Bio-Sensors" - Stanley Yang (CEO, NeuroSky)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
"From IA to AI in Healthcare" - Walter De Brouwer (CEO/Founder, doc.ai/Scanadu)Hyper Wellbeing
"From IA to AI in Healthcare" - Walter De Brouwer (CEO/Founder, doc.ai/Scanadu)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
"Electronics for Behavioral Health" - Jim Doscher (GM Healthcare, Analog Devi...Hyper Wellbeing
"Electronics for Behavioral Health" - Jim Doscher (GM Healthcare, Analog Devices, Inc.)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
"Body Analytics for Triggering Healthier, Happier and more Productive Lives" ...Hyper Wellbeing
"Body Analytics for Triggering Healthier, Happier and more Productive Lives" - Joni Kettunen (CEO, Firstbeat)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
"Beyond Quantified Self: How Quantifying Everything Is Not Enough To Improve ...Hyper Wellbeing
"Beyond Quantified Self: How Quantifying Everything Is Not Enough To Improve Societal Wellbeing" - Carlos Rodarte (Founder, Volar Health)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
"Wearables, Biometrics and Mindfulness as Medicine" - Joe Burton (Founder/CEO...Hyper Wellbeing
"Wearables, Biometrics and Mindfulness as Medicine" - Joe Burton (Founder/CEO, whil)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
"The Future of Sleep with Neurotechnology" - Anant Sachetee (Rythm)Hyper Wellbeing
"The Future of Sleep with Neurotechnology" - Anant Sachetee (Rythm)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
"Augmenting Human Decision Making: Machine Intelligence Could Help Eradicate ...Hyper Wellbeing
"Augmenting Human Decision Making: Machine Intelligence Could Help Eradicate Most Chronic Diseases" - Victor Chapela (Founder/CEO, Suggestic)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
"Using Data Science to Design Effective Precision Preventative Behavioral Med...Hyper Wellbeing
"Using Data Science to Design Effective Precision Preventative Behavioral Medicine" - Ryan Quan (Data Scientist, Omada Health)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
Satish K. Gupta, Ramesh C. Sawhney, Lajpat Rai , V. D. Chavan, Sameer Dani, Ramesh C. Arora,
W. Selvamurthy, H. K. Chopra, Navin C. Nanda
Indian Heart Journal 2011; 63:461-469
Managing DM and thyroid disease in shift workersNemencio Jr
This slide deck discusses the effects of shift work on physiology and behavior of thyroid axis and beta cell function and risk of diabetes, including glucose control among those with diabetes. Management strategies are also discussed
Works Cited Milne, Anne C., Alison Avenell, and Jan Potter. Meta-.docxkeilenettie
Works Cited
Milne, Anne C., Alison Avenell, and Jan Potter. "Meta-Analysis: Protein and Energy Supplementation in Older People."
Annals of Internal Medicine
144.1 (2006): 37-48.
ProQuest.
Web. 1 Oct. 2014.
Meta-Analysis: Protein and Energy Supplementation in Older People Anne C. Milne, MSc; Alison Avenell, MD; and Jan Potter, MBChB Background: Protein and energy undernutrition is common in older people, and further deterioration may occur during illness. Purpose: To assess whether oral protein and energy supplementa tion improves clinical and
nutritional outcomes for older people in the hospital, in an institution, or in the community. Data Sources: Cochrane Central Register of Controlled Trials (CEN TRAL), MEDLINE, EMBASE,
HealthStar, CINAHL, BIOSIS, and CAB abstracts. The authors included English- and non-English-language studies and hand-searched journals, contacted manufacturers, and sought information from trialists. The date of the most recent search of CENTRAL and MEDLINE is June 2005. Study Selection: Randomized and quasi-randomized controlled tri als of oral protein and energy
supplementation compared with placebo or control treatment in older people. Data Extraction: Two reviewers independently assessed trials for inclusion, extracted data, and assessed trial quality. Differences were resolved by consensus. Data Synthesis: Fifty-five trials were included (n = 9187 randomly tions (Peto odds ratio, 0.72 [95% Cl, 0.53 to 0.97]) and reduced mortality (Peto odds ratio, 0.66 [CI, 0.49 to 0.90]) for those un dernourished at baseline. Few studies reported evidence that suggested any change in mortality, morbidity, or function for those given supplements at home. Ten trials reported gastrointestinal disturbances, such as nausea, vomiting, and diarrhea, with oral supplements. Limitations: The quality of most studies, as reported, was poor, particularly for concealment of allocation and blinding of outcome assessors. Many studies were too small or the follow-up time was too short to detect a statistically significant change in clinical out come. The clinical results are dominated by 1 very large recent trial in patients with stroke. Although this was a high-quality trial, few participants were undernourished at baseline. Conclusions: Oral nutritional supplements can improve nutritional status and seem to reduce mortality and complications for under nourished elderly patients in the hospital. Current evidence does not support routine supplementation for older people at home or for well-nourished older patients in any setting. assigned participants). For patients in short-term care hospitals who were given oral supplements, evidence suggested fewer complica-Ann Intern Med. 2006:144:37-48. For author affiliations, see end of text.
www.annals.OIJ
ndernutrition among older people is a continuing source of concern (1, 2). Older people have longer periods of illness and longer hospital stays (3), and data show tha.
Harnessing the Power of Data From Our Bodies – Toward Personalized Preventive...Larry Smarr
10.11.01
Invited Talk
8th Latin American Seminar on Science and Health Journalism at the Institute of the Americas on UCSD Campus
Title: Harnessing the Power of Data From Our Bodies – Toward Personalized Preventive Medicine
La Jolla, CA
5 years of “Rare” Progress Research: Cheryl Rockman-Greenberg, Max Rady College of Medicine, University of Manitoba
Rare Disease Day Conference 2020 March 9-10
Let's dive deeper into the world of ODC! Ricardo Alves (OutSystems) will join us to tell all about the new Data Fabric. After that, Sezen de Bruijn (OutSystems) will get into the details on how to best design a sturdy architecture within ODC.
Connector Corner: Automate dynamic content and events by pushing a buttonDianaGray10
Here is something new! In our next Connector Corner webinar, we will demonstrate how you can use a single workflow to:
Create a campaign using Mailchimp with merge tags/fields
Send an interactive Slack channel message (using buttons)
Have the message received by managers and peers along with a test email for review
But there’s more:
In a second workflow supporting the same use case, you’ll see:
Your campaign sent to target colleagues for approval
If the “Approve” button is clicked, a Jira/Zendesk ticket is created for the marketing design team
But—if the “Reject” button is pushed, colleagues will be alerted via Slack message
Join us to learn more about this new, human-in-the-loop capability, brought to you by Integration Service connectors.
And...
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Akshay Agnihotri, Product Manager
Charlie Greenberg, Host
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Clients don’t know what they don’t know. What web solutions are right for them? How does WordPress come into the picture? How do you make sure you understand scope and timeline? What do you do if sometime changes?
All these questions and more will be explored as we talk about matching clients’ needs with what your agency offers without pulling teeth or pulling your hair out. Practical tips, and strategies for successful relationship building that leads to closing the deal.
Epistemic Interaction - tuning interfaces to provide information for AI supportAlan Dix
Paper presented at SYNERGY workshop at AVI 2024, Genoa, Italy. 3rd June 2024
https://alandix.com/academic/papers/synergy2024-epistemic/
As machine learning integrates deeper into human-computer interactions, the concept of epistemic interaction emerges, aiming to refine these interactions to enhance system adaptability. This approach encourages minor, intentional adjustments in user behaviour to enrich the data available for system learning. This paper introduces epistemic interaction within the context of human-system communication, illustrating how deliberate interaction design can improve system understanding and adaptation. Through concrete examples, we demonstrate the potential of epistemic interaction to significantly advance human-computer interaction by leveraging intuitive human communication strategies to inform system design and functionality, offering a novel pathway for enriching user-system engagements.
Accelerate your Kubernetes clusters with Varnish CachingThijs Feryn
A presentation about the usage and availability of Varnish on Kubernetes. This talk explores the capabilities of Varnish caching and shows how to use the Varnish Helm chart to deploy it to Kubernetes.
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Search and Society: Reimagining Information Access for Radical FuturesBhaskar Mitra
The field of Information retrieval (IR) is currently undergoing a transformative shift, at least partly due to the emerging applications of generative AI to information access. In this talk, we will deliberate on the sociotechnical implications of generative AI for information access. We will argue that there is both a critical necessity and an exciting opportunity for the IR community to re-center our research agendas on societal needs while dismantling the artificial separation between the work on fairness, accountability, transparency, and ethics in IR and the rest of IR research. Instead of adopting a reactionary strategy of trying to mitigate potential social harms from emerging technologies, the community should aim to proactively set the research agenda for the kinds of systems we should build inspired by diverse explicitly stated sociotechnical imaginaries. The sociotechnical imaginaries that underpin the design and development of information access technologies needs to be explicitly articulated, and we need to develop theories of change in context of these diverse perspectives. Our guiding future imaginaries must be informed by other academic fields, such as democratic theory and critical theory, and should be co-developed with social science scholars, legal scholars, civil rights and social justice activists, and artists, among others.
Kubernetes & AI - Beauty and the Beast !?! @KCD Istanbul 2024Tobias Schneck
As AI technology is pushing into IT I was wondering myself, as an “infrastructure container kubernetes guy”, how get this fancy AI technology get managed from an infrastructure operational view? Is it possible to apply our lovely cloud native principals as well? What benefit’s both technologies could bring to each other?
Let me take this questions and provide you a short journey through existing deployment models and use cases for AI software. On practical examples, we discuss what cloud/on-premise strategy we may need for applying it to our own infrastructure to get it to work from an enterprise perspective. I want to give an overview about infrastructure requirements and technologies, what could be beneficial or limiting your AI use cases in an enterprise environment. An interactive Demo will give you some insides, what approaches I got already working for real.
Key Trends Shaping the Future of Infrastructure.pdfCheryl Hung
Keynote at DIGIT West Expo, Glasgow on 29 May 2024.
Cheryl Hung, ochery.com
Sr Director, Infrastructure Ecosystem, Arm.
The key trends across hardware, cloud and open-source; exploring how these areas are likely to mature and develop over the short and long-term, and then considering how organisations can position themselves to adapt and thrive.
GDG Cloud Southlake #33: Boule & Rebala: Effective AppSec in SDLC using Deplo...James Anderson
Effective Application Security in Software Delivery lifecycle using Deployment Firewall and DBOM
The modern software delivery process (or the CI/CD process) includes many tools, distributed teams, open-source code, and cloud platforms. Constant focus on speed to release software to market, along with the traditional slow and manual security checks has caused gaps in continuous security as an important piece in the software supply chain. Today organizations feel more susceptible to external and internal cyber threats due to the vast attack surface in their applications supply chain and the lack of end-to-end governance and risk management.
The software team must secure its software delivery process to avoid vulnerability and security breaches. This needs to be achieved with existing tool chains and without extensive rework of the delivery processes. This talk will present strategies and techniques for providing visibility into the true risk of the existing vulnerabilities, preventing the introduction of security issues in the software, resolving vulnerabilities in production environments quickly, and capturing the deployment bill of materials (DBOM).
Speakers:
Bob Boule
Robert Boule is a technology enthusiast with PASSION for technology and making things work along with a knack for helping others understand how things work. He comes with around 20 years of solution engineering experience in application security, software continuous delivery, and SaaS platforms. He is known for his dynamic presentations in CI/CD and application security integrated in software delivery lifecycle.
Gopinath Rebala
Gopinath Rebala is the CTO of OpsMx, where he has overall responsibility for the machine learning and data processing architectures for Secure Software Delivery. Gopi also has a strong connection with our customers, leading design and architecture for strategic implementations. Gopi is a frequent speaker and well-known leader in continuous delivery and integrating security into software delivery.
Dev Dives: Train smarter, not harder – active learning and UiPath LLMs for do...UiPathCommunity
💥 Speed, accuracy, and scaling – discover the superpowers of GenAI in action with UiPath Document Understanding and Communications Mining™:
See how to accelerate model training and optimize model performance with active learning
Learn about the latest enhancements to out-of-the-box document processing – with little to no training required
Get an exclusive demo of the new family of UiPath LLMs – GenAI models specialized for processing different types of documents and messages
This is a hands-on session specifically designed for automation developers and AI enthusiasts seeking to enhance their knowledge in leveraging the latest intelligent document processing capabilities offered by UiPath.
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👨🏫 Andras Palfi, Senior Product Manager, UiPath
👩🏫 Lenka Dulovicova, Product Program Manager, UiPath
Mission to Decommission: Importance of Decommissioning Products to Increase E...
"How Scientific Wellness will Drive The Future of Health" - Nathan Price (Professor, Institute of Systems Biology)
1.
2. How Scientific Wellness will
Drive the Future of Health
Nathan Price, PhD
Institute for Systems Biology
Seattle, WA
Hyper Wellbeing
November 13, 2016
@ISBNathanPrice
3. Disclosures
• Dr. Price is a Co-Founder of Arivale, which
partially funded and may license discoveries
resulting from the Hundred Person Wellness
Project (to be described).
• Dr. Price serves on Scientific Advisory Board of
Habit, a new personalized nutrition company
Founders
Clayton Lewis, CEO and Co-founder
Maveron, MarketLeader, Harborview Medical Center, Capitol
Hill
Lee Hood, MD, PhD, Co-founder, SAB Chair
ISB, Amgen, National Academies, Presidential Medal
Nathan Price, PhD, Co-founder, Board of Directors
ISB, University of Illinois, Urbana-Champaign, UCSD, UW
7. Conceptual Themes of P4 Medicine
Disease DemystifiedWellness Quantified
P4 Medicine
Predictive
Preventive
Personalized
Participatory
Scientific Wellness Industry Disease Industry
8. Proposing the 100K Wellness Project
Nature,
News
piece,
(2014)
Hood and Price, Science Translational Medicine (2014)
Hood and Price,
Clinical Omics,
(2014)
9. Scientific Wellness:
Two Integrated Directions
Arivale
• A consumer facing
scientific wellness
company
• 5,000 individuals in the
first 18 months
• Transform how biotech
industry operates
ISB-Providence
• Dense, dynamic, personal data clouds
• Research to validate wellness metrics
• Research for better assays
• Optimize wellness
• Study wellness to disease transitions
• Study disease [progression, response
to therapy and transition to wellness
10. PIONEER 100 PROJECT
Principal Investigators: Lee Hood and Nathan Price
The 100K Wellness Project was initiated in 2014 with the generation of dynamic data clouds for 108
individuals. These data provided spectacular insights into what it is to be well and the nature of
wellness to disease transitions (and vice versa).
11. • 108 participants
• Age range: 20s to 88+
• 9-month study
launched March 2014
• IRB approved
• Evaluation / insights
for next phase
• Whole genome sequence
• Detailed blood, urine, saliva
measurements 3x
• Gut microbiome 3x
• Continual self-tracking and lifestyle
monitoring
• Data integration & correlations
• Monthly coaching sessions on
actionable data
• Discovery research
• Events and education
12. Assays / Measurements—108 Pioneers
Database
of actionable
possibilities that
will grow over
time
GENOME
Whole Genome
Sequencing.
SNPs Millions
LABS
Detailed lab tests 3x
(blood, urine, saliva)
Clinical chem. 150
Metabolites 700
Proteins 400
SELF-
TRACKING
Continual
self-tracking
& lifestyle
monitoring
MICROBIOME
Gut Microbiome
3x
Creating dense and dynamic personal data clouds
13. Wellness coaching for participants
Sandi Kaplan, MS, RD Craig Keebler, MD
Wellness Coach Study Physician
14. Clinical Labs Discovery:
Improvements in blood health with behavioral coaching
50%
55%
60%
65%
70%
75%
80%
85%
90%
95%
100%
Cardiovascular Diabetes Inflammation Nutrition
%changeinout-of-rangemeasurements
Baseline 3 months 6 months
Improved by 33%Improved by 6% Improved by 12% Improved by 21%
15. Clinical Labs Discovery:
Significant pre-diabetes improvements
Seven participants with pre-diabetes were completely normalized in six months
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
HbA1c
(Glycated hemoglobin)
Fasting glucose HOMA
(Insulin resistance)
Insulin
%changeinout-of-rangemeasurements
Baseline 3 months 6 months
Improved by 19%Improved by 38% Improved by 55% Improved by 56%
16. A wellness to disease transition—genetics
plus environment—an actionable
possibility
17. • Blood + Genetics illuminated the effects of increasing copies of the Hemochromatosis variant
• Left untreated, this disorder could lead to cartilage damage, liver cancer, diabetes, and heart
disease: Easily treated by regular blood donations to reduce the iron stores
• One participant ALREADY had cartilage damage from his undiagnosed disease
• Subsequent family genetic testing detected other family members at risk
0.0
50.0
100.0
150.0
200.0
250.0
Zero copies of rare
variant
(86 individuals)
One copy of rare
variant
(12 individuals)
Two copies of rare
variant
(2 individuals)
Ferritinlevels
Baseline 3 months
Genetics and Clinical Labs: Hemochromatosis
Detected risk of a deadly disease in two participants
20. • Cholesterol is positively
associated with alpha-
tocopherol (Vitamin E)
• Cholesterol is negatively
associated with
endogenous thyroxine
• A beneficial side effect of
the drug thryroxine
(Synthroid) is lowering LDL
cholesterol
Total cholesterol
community
24. Estimated risk for the
disease or trait relative
to a population
GWAS variants have been determined for about 60
diseases and traits
Variant
rs6827
Variant
rs8572
Variant
rs68883 Variant
rs0994
Variant
rs9769
Variant
rs14445
Var
iant
Variant
rs111393
Variant
rs6837
Variant
rs5837
Variant
rs68279
Variant
rs59583
Variant
rs1352
Variant
rs6827
Variant
rs68883
Variant
rs9769
Variant
rs14445
Variant
rs5837
Detrimental VariantBeneficial Variant
0
20
40
60
80
100
120
140
Cumulative Risk
Below average
Distribution from 2000 Genomes
ADHD COPD Myopia
Alzheimer's disease Crohn's disease Obesity
Anorexia Esophageal cancer Osteoarthritis
Asthma Gout Osteoporosis
Atrial fibrillation Grave's disease Ovarian cancer
Breast cancer Hematocrit Pancreatic cancer
Bipolar disorder Hypertension Parkinson's disease
Blood pressure Hypothyroidism Primary biliary cirrhosis
Bone mineral density Inflammatory bowel disease Prostate cancer
Inflammation Iron levels Psoriasis
Calcium Lung Cancer Rheumatoid arthritis
Cardiovascular disease Lupus Schizophrenia
Celiac disease Macular degeneration Stroke
Cholesterol levels Magnesium levels Type 1 Diabetes
Chronic kidney disease Metabolic syndrome Type 2 Diabetes
Colorectal cancer Migraine Ulcerative colitis
Coronary heart disease Multiple sclerosis Urate levels
25. Nutrient measurements correlated
with genetic predisposition for IBD
cystine
(plasma)
glutathione
(cytosol)
Sido, B., Hack, V., Hochlehnert, A., Lipps, H., Herfarth, C., and Dröge, W.
(1998). Impairment of intestinal glutathione synthesis in patients with
inflammatory bowel disease. Gut 42, 485–492.
Ulcerative colitis
activity
Pilot Study Correlation
Network
cysteine
(cytosol)
-2
0
2
4
6
-4
plasmacystine
-4 -2 0 2 4
Inflammatory bowel disease genetic
score
N = 107
rho = -
0.44
p =
2.3e-6
q = 0.03
26. Dense, Dynamic Personal
Data Clouds
These personalized data clouds are the foundation
of what Precision Medicine should be.
27. Enabling Individuals to take Responsibility for
their Own Wellness (and Disease)
Individuals taking responsibility for their own health
will dramatically reduce the cost of healthcare
28. Project Leadership
• Leroy Hood, MD, PhD
• Nathan Price, PhD
• Sean Bell, Business Director
Data Analytics
• Nathan Price, PhD – Analytics Lead
Gustavo Glusman, PhD, Genomics
• Andrew Magis, PhD, Multi-omics
• John Earls, Data integration
Project Management
• Kristin Brogaard, PhD Project Manager
• Sara Mecca, Project Assistant
• Mary Brunkow, PhD, Project Coordinator
Medical Advisory Board
• Robert Green, MD
• Jane Guiltinan, ND
• Michael Raff, MD
• Sarah Speck, MD
Communications
• Gretchen Sorenson, Consultant
• Hsiao-Ching Chou, Commun. Director
Participant Engagement
• Jennifer Lovejoy, PhD, VP Clinical Affairs
• Sandi Kaplan, Wellness Coach
• Craig Keebler, MD, Study Physician
ISB Hundred Person Wellness Project: Team
Special thanks to our funders: Robert Wood Johnson Foundation and
M.J. Murdock Charitable Trust
@ISBNathanPrice
Editor's Notes
Actionable big data for systems medicine and proactive healthcare
Steven Schroeder et al.
New England J Medicine, 2007
McGinnis JM, Williams-Russo P, Knickman JR. Health Aff (Millwood) 2002
Growth will be driven primarily by preventive health and wellness categories such as vitamins, nutrition, weight management and fortified foods and beverages; fitness and mind; alternative medicine and workplace wellness
The global POC market was worth $13.8 billion in 2011. By 2018, the market is expected to grow to $24 billion in the U.S. alone.
Thu Mar 26, 2015 12:13am EDT
By Sharon Begley from a survey of 121 representative U.S. employers by Fidelity Investments and the National Business Group on Health
NEW YORK (Reuters) - Employers have ratcheted up the financial incentives they offer workers to participate in wellness programs to a record $693 per employee, on average, this year from $594 in 2014 and $430 five years ago, found a report released on Thursday (Companies with more than 20,000 employees are offering an average of $878
Arivale-a wellness sciences company—consumer facing —generate 10,000 dense and dynamic individual data clouds in next 18 months—may really lead the large-scale adoption of P4 medicine and the democratization of healthcare—one of the first companies in the scientific wellness sector
The 100,000 person wellness project—academic—discovery science at ISB—pioneer assays (to the smart phone) and pioneer the integrative and modeling analytics—seek Precision Medicine funding—focus on both wellness and early disease transitions and on following disease to therapy to wellness transitions.
100 participants
9 month study starting in March
They will get:
there whole genome sequenced
Detailed Blood measurements 3 times
detailed urine and saliva measurements 3 times
Gut microbiome 3 times
Continual activity and lifestyle monitoring
discovery research on their samples
Coaching component to focus on actionable information for the participants and help guide them through the study
Regulatory: We are IRB approved
Multiple events with guest speakers held throughout the 9 months to foster community and educations
For bio-sample collection participants will go to blood draw centers for will be given kits to collect samples at home
Transition to Jennifer
Green no highlights
Remove highlights
Spell out numbers
Optional Title Slide
What might this mean: paint the picture for the board
Have a summary slide: arivale research portal can provide the genetic risk of populations for specific diseases
Patent: idea that we can identify the genetic risk for a given population and use that risk disposition to identify molecules that are relevant to those disease associations
What about the guy that was diagnosed during the study, is he low