This document discusses viewing a house as an interconnected system. It provides an overview of various house systems including diagnostics using a whole-house approach, air movements, moisture, and ventilation. Common indoor air quality concerns such as formaldehyde, lead, radon, and mold are also reviewed. Maintaining elements like heating systems, drainage planes, and ventilation is important for a house's comfort, health, safety, energy efficiency, and durability. Understanding how building occupants and their environment interact with a house as a complex, integrated system can help in designing, building, or renovating homes.