In 1895, Wilhelm Roentgen discovered X-rays while experimenting with cathode ray tubes. He noticed a plate glowing in a dark room even when the tube was covered, leading him to take the first X-ray photo of his wife's hand. Roentgen could not explain the nature of these new rays, so he called them X-rays. In 1901, Roentgen received the Nobel Prize in Physics for his discovery. X-rays revolutionized medicine by allowing doctors to see inside the body. Later advances like CT scans provided more detailed 3D views of organs.