This document provides a course outline for Histology II, an undergraduate histology course offered at a Medical School. The course is 4 credits and includes both lectures and laboratory practice. It aims to teach students about the microstructure of organ systems and the relationship between structure and function. Assessment includes summative and conclusive evaluations of laboratory work, a final written exam, and an oral presentation. The course covers the nervous, integumentary, immune, digestive, respiratory, endocrine, urinary, and genital organ systems through both lectures and laboratory study of real and virtual histological specimens.

1. COURSE OUTLINE
(1) GENERAL
SCHOOL Health Science
ACADEMIC UNIT Medical School
LEVEL OF STUDIES Undergraduate
COURSE CODE SEMESTER IV
COURSE TITLE
Histology II
Course coordinators and Instructors :
Yotanna Dalavanga
Stefanos Kalamidas
INDEPENDENT TEACHING ACTIVITIES
if credits are awarded for separate components of the course, e.g.
lectures, laboratory exercises, etc. If the credits are awarded for the
whole of the course, give the weekly teaching hours and the total credits
WEEKLY
TEACHING
HOURS
CREDITS
Lectures 4 5
Laboratory practice Total teaching
hours
8
Hours/student
2
Add rows if necessary. The organisation of teaching and the teaching
methods used are described in detail at (d).
COURSE TYPE
general background,
special background, specialised general
knowledge, skills development
Mandatory
Organ histology
Structure and function relations, interaction and
parameters determining the final structural outcome.
PREREQUISITE COURSES:
LANGUAGE OF INSTRUCTION
and EXAMINATIONS:
Greek
IS THE COURSE OFFERED TO
ERASMUS STUDENTS
No [at the present]
COURSE WEBSITE (URL) Ιστολογια ΙΙ: http://ecourse.uoi.gr/course/view.php?id=772
(2) LEARNING OUTCOMES
Learning outcomes
The course learning outcomes, specific knowledge, skills and competences of an appropriate level, which the students will
acquire with the successful completion of the course are described.
Consult Appendix A
 Description of the level of learning outcomes for each qualifications cycle, according to the Qualifications Framework of
the European Higher Education Area
 Descriptors for Levels 6, 7 & 8 of the European Qualifications Framework for Lifelong Learning and Appendix B
 Guidelines for writing Learning Outcomes
At the completion of Histology II the students should understand and appreciate
the structure and micro-architecture of the organs and their microenvironment, as well as sub-
cellular structures, as these are revealed under the microscope [light and electron], with the aid
of several methods of classic and molecular histology.
These elements concerning morphological elements beyond light microscopy and their
importance are always stressed as part of the lectures and therefore must be appreciated in the

2. context of the relevant information concerning the physiology, cell biology and biochemistry of
the organ under study.
In short they should be able to understand the relation and correlation between the structure
and the function of every particular organ and the underlined “philosophy” drive, under the fine,
final structure of an organ.
*structure-function relationship*
General Competences
Taking into consideration the general competences that the degree-holder must acquire (as these appear in the Diploma
Supplement and appear below), at which of the following does the course aim?
Search for, analysis and synthesis of data and
information, with the use of the necessary technology
Adapting to new situations
Decision-making
Working independently
Team work
Working in an international environment
Working in an interdisciplinary environment
Production of new research ideas
Project planning and management
Respect for difference and multiculturalism
Respect for the natural environment
Showing social, professional and ethical responsibility and
sensitivity to gender issues
Criticism and self-criticism
Production of free, creative and inductive thinking
……
Others…
…….
Search for, analysis and synthesis of data and information, with the use of the necessary
technology
Adapting to new situations
Decision-making
Working independently
Team work
Working in an international environment
Working in an interdisciplinary environment
Production of new research ideas
Showing social, professional and ethical responsibility and sensitivity to the patients
Criticism and self-criticism
Production of free, creative and inductive thinking
Respect for the human structure
Respect for the evolution and adaptability of the living organisms and therefore for the natural
environment

3. (3) SYLLABUS
Histology II includes the study of all the organ systems:
nervous system : CNS and sensory organs
integumentary system : skin and appendages.
immune system : introduction to immune response, bone marrow, thymus, lymph nodes,
spleen, diffuse lymphoid tissue
digestive system : mouth cavity, oesophagus, stomach, small and large intestine, GALT
-- glands related to the system : liver, pancreas, major salivary glands [parotid,
subligual, submaxillary]
respiratory system : upper respiratory system –nose, rhinopharynx, larynx, epiglottis
lower respiratory system –trachea, bronchi, bronchioles, alveoli,
interstitium, pleura, BALT
endocrine system : hypothalamus, hypothalamohypophysial axon,
pituitary / hypophysis [neurohypophesis, adenohypophesis], epiphysis,
thyroid gland, parathyroids, adrenal gland, endocrine pancreas [isles of
Langerhans
urinary system : kidney, ureter, urinary bladder, urethra
genital system : i)male : scrotum,
testis, [spermatogenesis / spermiogenesis,
hypophesis/testis interactions],
epididymis , spermatic tone, spermatic cord,
spermatic ampula, prostates, penis, male urethra
ii) female : ovary and ovary cycle [ovulation, hypophecial/ovary functional
interactions and treir results in the structural changes and the
overall changes of the organ morphology],
oviduct,
uterus - function related changes of the organ’s morphology and
correlation with the ovary structure/function changes
- function related changes of the organ’s morphology and
correlation with pregnancy
vagina, external genitalia, female urethra
placenta
mammary gland
(4) TEACHING and LEARNING METHODS - EVALUATION
DELIVERY
Face-to-face, Distance learning, etc.
Face to face [lectures / laboratory instructions]
Distance learning
USE OF INFORMATION AND
COMMUNICATIONS TECHNOLOGY
Use of ICT in teaching, laboratory education,
communication with students
The use of ICT in teaching and laboratory education is
constant and unrestricted as well as the communication with
the students
The educational procedure is coming through the uoi / e-

4. course site, either on the spot, during the laboratory practice,
or via educational material available at the site throughout the
semester.
There is a steady, constant communication with the students
via e-mail, video conferences and chat., apart from the fixed
days and hours in the lab for face to face communication
TEACHING METHODS
The manner and methods of teaching are
described in detail.
Lectures, seminars, laboratory practice,
fieldwork, study and analysis of bibliography,
tutorials, placements, clinical practice, art
workshop, interactive teaching, educational
visits, project, essay writing, artistic creativity,
etc.
The student's study hours for each learning
activity are given as well as the hours of non-
directed study according to the principles of
the ECTS
Activity Semester workload
Lectures
analysis of the
morphology of each organ
in relation with its
function
open for all the students
of the semester
52
Laboratory practice
In groups of 6-8 students
The laboratory practice is
focused in the
simultaneous study of
real/glass and digital
histological preparations,
(glass slides on
microscope and virtual
slides from internet
sources, respectively).
The students use the
microscopes and glass
slides of the lab facilities,
and they brink over their
laptops or tablets in order
to study the virtual slides
in situ, and to have all the
educational material
uploaded on our site of
the e-course, available
anytime. For the same
raison they brink over
their text books as well.
During the laboratory
practice hours the
instructors are always
present, available for
supporting the students’
study of the glass and
virtual slides
The students are also
supervised in order to
complete the study of the
assigned organs, with
question concerning the
comprehension of the
morphology and the
obligation of completing
the simple tasks of
identifying certain
structures, or locating
such structures on the
specimens used in the
particular lab exercise.
26

5. Projects and essays
The students prepare
labelled
photomicrographs of the
currently studying
organs, taken from the
virtual studies, using
appropriate software and
programmes available in
the internet
They also prepare essays
mainly concerning the
structure / function
relation analysis,
as well as pathological
outcomes of disturbed or
genetically altered
structure of various
organs .
The essays are presented
in an oral and/or written
form, throughout the
semester which is also
available in the site of
Histology II of the uoi/e-
course.
The project in
preparation has as its
main subject, the
construction of simple
structures [with
everyday’s simple
materials] of the
functional units of various
organs in the context of
the comprehension part
of the teaching, e.g. that
of the fundamental
structure/function
relationship
25
Tutorials
the teachers/instructors
are always available on
line and –as physical
presence- during the lab
practise and the pre-
assigned days and hours,
or after previous
arrangement, to guide
and help the students in
every matter concerning
their study on Histology II
-project, essay,
comprehension of virtual
slides and microscopic
specimens-.
They also instruct the
students in the field of
literature search,
10

6. proposing the
appropriate books
journals, and articles, and
discussing with the
students the appropriate
way to analyse the
available data.
The above task is
performed either with
individual students or
groups of students in case
e.g. of discussing the
progress of an essay .
Individual study
apart of every student’s
method of study we
contribute with
comprehensive questions
and self assessment
quizzes, prepared by the
instructors/teachers
using the appropriate
software. The students
are using their laptops
and with the aid of
moodle or google forms,
and complete and submit
a quiz comprised by
images from the virtual
slides, of which they are
obliged to recognise the
organ presented, firstly in
a panoramic view, and
subsequently structures
marked on it in higher
magnifications. They
have the option of
multiple attempts to help
them finally, through
careful study of the
specimen and
simultaneous use of all
sources available, to reach
the right answer.
The grading of the tests is
automatically presented
upon submission as well
as the right answers.
40
Course total 153
STUDENT PERFORMANCE
EVALUATION
Description of the evaluation procedure
Language of evaluation, methods of
evaluation, summative or conclusive, multiple
choice questionnaires, short-answer questions,
open-ended questions, problem solving,
written work, essay/report, oral examination,
public presentation, laboratory work, clinical
examination of patient, art interpretation,
other
the evaluation
is conducted in Greek and comprises of
i) evaluation of laboratory work
1. summative and 2. conclusive
--The summative evaluation [10%]
is performed at the completion of the
laboratory study of 1-3 organ systems. The
students are using their laptops and with the
aid of moodle or google forms, complete and
submit a quiz prepared by the teachers wjth

7. (5)
ATTACHED BIBLIOGRAPHY
- Suggested bibliography:
- Related academic journals:
-Προτεινόμενη Βιβλιογραφία :
-Συναφή επιστημονικά περιοδικά:
- Greek Books
Ιστολογία : το κύτταρο και οι ιστοί υπό Κωτούλας , Όθων Β., Κωτούλα , Αγγελική
Ιωάννινα : [Εκδόσεις Γ. Τσόλη] 1997
Ιστολογία: τα συστήματα οργάνων υπό Κωτούλας , Όθων Β., Πανεπιστήμιο Ιωαννίνων -
Τυπογραφείο, Πανεπιστήμιο Ιωαννίνων - Ιατρική Σχολή Ιωάννινα : [Τυπογραφείο Πανεπιστημίου
Ιωαννίνων] 1999
Ιστολογία υπό Μιχαήλ Σωτήριος Γ. Θεσσαλονίκη : Εγνατία 1982
- English Books and Translation of English Books in Greek
Ιστολογία με στοιχεία κυτταρικής βιολογίας : εισαγωγή στην ιστοπαθολογία υπό Kierszenbaum ,
Abraham L.. Tres , Laura L., Μετάφραση Γοργούλης Βασίλης, Κίττας Χρήστος, Κουλούκουσα
Μυρσίνη, Τόγια Κωνσταντίνα. Αθήνα : Π. Χ. Πασχαλίδης : Brokjen Hill c2013
Gartner, Leslie P. Ιστολογία / Leslie P. Gartner, James L. Hiatt • μετάφραση Γεώργιος Ν.
Αντωνακόπουλος • επιμέλεια Γεώργιος Ν. Αντωνακόπουλος. - 3η έκδ. - Αθήνα : Παρισιάνου Α.Ε.,
2011.
Specifically-defined evaluation criteria are
given, and if and where they are accessible to
students.
the appropriate software. The test is
comprised by images from the virtual slides,
of which they are obliged to recognise the
organ presented, firstly in a panoramic vew,
and subsequently structures marked on it in
higher magnifications. The grading of the
tests is automatically presented upon
submission as well as the right answers.
--The conclusive lab evaluation [20%] is a
combination of
*a digital test in the same format as the
summative, only that this one includes all the
organ systems studied, and
*a test on identification of specimens on
glass slides under the microscope.
ii) final/conclusive written examination,[60%],
using multiple choice, true/false and
multiple answer questions, short answer
questions, open ended questions.
iii) oral presentation of the assigned essay by a
group of 7-8 students. [10%]

8. Βασική Ιστολογία υπό Junqueira Luis C. ,Carneiro Jose. Μετάφραση Κίττας Χρήστος, Αθήνα :
Ιατρικές Εκδόσεις Πασχαλίδη 2004
Wheater's Λειτουργική Ιστολογία υπό Wheater , Paul R., Burkitt , H. George, Daniels , Victor G.
Μετάφραση Κίττας Χρήστος, Αθήνα : Πασχαλίδης 2002
Ιστολογία του ανθρώπου υπό Stevens Alan, Lowe James S. Μετάφραση Κίττας , Χρήστος Αθήνα :
Πασχαλίδης 1998
Histology for pathologists υπό Mills , Stacey E., Philadelphia : Lippincott Williams & Wilkins c2007
Histology: A Text and Atlas by Johannes A. G. Rhodin, Oxford University Press 1977
Histology: A Text and Atlas with Correlated Cell and Molecular Biology, 6th ed, Michael H. Ross,
Wojciech Pawlina, Walters Kluwer, Lippincott Williams and Wilkins, 2011
Histology Atlases
Εγχειρίδιο ιστολογίας υπό Gartner Leslie P. 1943-, Hiatt James L. 1934- Μετάφραση
Αντωνακόπουλος , Γεώργιος Ν. Αθήνα : Παρισιάνος 1998
Έγχρωμος άτλας ιστολογίας, κυτταρολογίας και μικροσκοπικής ανατομικής υπό Kuhnel , Wolfgang
1950- Μετάφραση Κοντόπουλος , Αλέξανδρος Ν. Αθήνα : Λίτσας 1986
Ιστολογία : έγχρωμος άτλαντας μικροσκοπικής ανατομίας υπό Hammersen Frithjof, Sobotta Johannes
1869-1945, Μτάφραση Κοντόπουλος , Αλέξανδρος Ν. Αθήνα : Παρισιάνος 1988
An atlas of histology υπό Zhang Shu-Xin, New York : Springer c1999
Di Fiore's atlas of histology with functional correlations υπό Eroschenko Victor P., Fiore Mariano S.
H. di Baltimore : Williams & Wilkins c2008
Journals
Experimental Cell Research
Journal of Cell Science
Histology and Histopathology
Microscopy Research and Technique
The Anatomical Record
The Journal of Cell Biology