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Clinical meeting
Presented By
Dr. Mir Aulad Hossain
Assistant Registrar
(FCPS Part-II Trainee)
Department of Paediatrics
Chattogram Maa-O-Shishu General Hospital
Particulars of patient
Name : Tasnim
Age : 6years
Sex : Female
Address : Hathazari, Chittagong
Date of admission: -15.07.2022
Date of examination: 17.07.2022
Presenting complaints
1. Rash in different sites of body for 6 days
2. Abdominal pain for 3 days
History of present illness
According to patient mother statement her child was
reasonably well 6 days back. Then she developed rash which
was first appeared in the extensor surface of both leg then
gradually involved in the buttock, back of chest and trunk.
Initially rash was pink in color than become reddish, non itchy.
rash was not associated with fever and itching. Mother Also
Complaints of abdominal pain for last 3 days which was dull
aching in nature, located around the umbilicus, non radiating
not aggravated or reduced by taking food and not associated
with vomiting.
Present illness (cont)
There was no history of fever ,joint pain, joint swelling,
epistaxis, gum bleeding, melena, hematuria no history of
taking any offending drug, exposure to ionizing radiation, . with
these complaints child was consulted with a registered
physician and treated with paracetamol and advice for
hospitalization for further evaluation and management.
h/o past illness
 h/o sore throat 1 weeks back.
BIRTH HISTORY:
 Child was born at term by normal vaginal delivery
 No H/o PNA
 Antenatal, prenatal, postnatal period was uneventful.
Feeding history
Child was on family diet .
IMMUNIZATION HISTORY:
Completely Immunized .
DEVELOPMENT HISTORY:
Age appropriate.
FAMILY HISTORY:
2nd issue of non consanguineous parents
No family member has such type of disease
Socioeconomic history
Father: Businessman
Mother: Housewife
Lives in pacca house. drinks tube well water and use
sanitary latrine
General examination
Appearance: ill looking, conscious; co-operative ,lying in
supine position
i/v cannula in situ. Afebrile,
anemia: mildly pale
Jaundice: absent
Cyanosis: Absent
Edema: Absent
Dehydration: Absent
clubbing: absent
Leuconychia: absent
Koilonychia :absent
General examination (Cont)
 Vital sign:
 Temp: Normal
 RR: 26 /min
 HR: 90 b/min
 BP : 90/50 mm of Hg (below 50th persentile)
 BCG Mark: Present
 No lymphadenopathy
 Ear nose throat: normal
 Sign of meningeal irritation: absent
 Bony tenderness :absent
General examination (Cont)
 Skin survey: Maculopapular rash present on the extensor surface of the
both legs, buttock,trunk,back of the chest of varying size and
shape.redish in colour ;rashes are palpable ,not blanced on pressure
and non tender.
 Diascopic test : Negative
 Anthropometry measurement:
 Weight-26 kg WAZ(-1.2 sd)
 Height-115 cm HAZ (-1sd)
 WHZ(-1SD)
 BMI: 19.6
Abdominal EXAMINATION:
 Abdomen:
 Inspection: shape –normal
Umbilicus centrally placed and inverted.
No visible peristalsis , mass or scar mark.
 Palpation: tenderness :present at periumbilical region.
No organomegaly present.
 Percussion: fluid thrill and
Shifting dullness – absent
 Auscultation: bowel sound present
External genitalia-normal
 NERVOUS SYSTEM:
Higher psychic function: intact
Cranial nerves: intact
Motor function: intact
Sensory function: intact
Co ordination: present
 PRECORDIUM EXAMINATION:
Shape of precordium: normal
no visible apical impulse
apex beat: left 5th intercostal space medial
TO mid clavicular line
 Thrill: absent
Heart rate: 90b/min; regular in character
 Heart sound: 1st and 2nd heart sound were audible
in all four cardiac areas
 Murmur: absent
 CHEST EXAMINATION:
 no chest deformity
 respiratory/rate: 26b/min
 breath sound vesicular
 no added sound
 OTHER SYSTEMIC EXAMINATION
REVEALED NO ABNORMALITY.
SALIENT FEATURE:
 Tasnim ,6years ,female child,2nd issue of non
consanguineous parents hailing from hathazari admitted in
CMOSHMC with the complaints of rash in different sites of
the body for 6 days. which involving extensor surface of
both lower limb ,buttock ,trunk and back of chest which was
maculopapular , varying size and shape.rashes are palpable
,not blanced on pressure and non tender,reddish in color.
Periumbilical pain for 3 days and no orgalomegaly present .
SALIENT FEATURE(Contd)
There was no history of joint pain, joint swelling,
epistaxis, gum bleeding, melena,hematuria no
history of taking any offending drugs, exposure to
ionizing radiation, on examination tasnim was ill
looking afebrile mildly pale, vitals are normal. No
bony tenderness present , BSUA was nil BCG
mark was present, anthropometrically well thriving
.
other systemic examination revels no abnormality.
Provisional diagnosis
 Henoch schonlein purpura(HSP)
DIFFERENTIAL
DIAGNOSIS:
 ITP (immune
thrombocytopenic purpura)
 Acute leukemia
 Aplastic anaemia

Investigations:
CBC : Hb% 10g/dL
ESR : 03 mm fall in 1st
hour
RBC : 5.12 million /cmm
WBC : 10.57x 10 /cmm
Platelet : 340,000/cmm
Neutrophils : 57%
Lymphocytes : 34%
Eosinophils : 05%
Monocytes : 04%
Basophils: OO%
 Red cell indices:
 Pcv:42.3
 MCV:82.6
 MCH:27.3
 MCHC:33
 RDW:12.2%
Urine routine examination:
 Color:straw
 Appearance:clear
 Albumin:nill
 Pus cell:6-8 pus cell
 RBC:nill
 Cast:
 Hyaline:nill
 Granular :nill
 RBC:nill
Investigation:
 Serum creatinin:o.5mg/dl
 Serum electrolyte:
 Na+:146mmol/l
 K+:4.2mmol/l
 Cl:106mmol/l
 hCO3:24mmol/l
Ultasonography of whole
abdomen :
 Mild thickening of bowel wall in right lumbar
region
 Partially contracted gall bladder
Treatment
 Counseling about the disease
 Maintenance of fluid and nutrition
 Tab paracetamol500 mg
 2/3rd +0+2/3rd
 Tab cortan 10mg
 1+0+1
Prognosis
 Excellent
 15-60% have 1 or more recurrence
 Chronic disease develops in 1-2 %
 <5% HSP nephritis have ESRD
 Long term prognosis depend son severity
and duration of GIT or renal involvement
Follow -up
 Blood pressure monitoring
 Bed side heat coagulation test
 Intake output chart
 Vital sign:
 After discharge f/up upto 4wk but it will be
recurrence within 4-6 month
THANK YOU

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Henoch Schonlein purpura in general population

  • 1. Clinical meeting Presented By Dr. Mir Aulad Hossain Assistant Registrar (FCPS Part-II Trainee) Department of Paediatrics Chattogram Maa-O-Shishu General Hospital
  • 2. Particulars of patient Name : Tasnim Age : 6years Sex : Female Address : Hathazari, Chittagong Date of admission: -15.07.2022 Date of examination: 17.07.2022
  • 3. Presenting complaints 1. Rash in different sites of body for 6 days 2. Abdominal pain for 3 days
  • 4. History of present illness According to patient mother statement her child was reasonably well 6 days back. Then she developed rash which was first appeared in the extensor surface of both leg then gradually involved in the buttock, back of chest and trunk. Initially rash was pink in color than become reddish, non itchy. rash was not associated with fever and itching. Mother Also Complaints of abdominal pain for last 3 days which was dull aching in nature, located around the umbilicus, non radiating not aggravated or reduced by taking food and not associated with vomiting.
  • 5. Present illness (cont) There was no history of fever ,joint pain, joint swelling, epistaxis, gum bleeding, melena, hematuria no history of taking any offending drug, exposure to ionizing radiation, . with these complaints child was consulted with a registered physician and treated with paracetamol and advice for hospitalization for further evaluation and management.
  • 6. h/o past illness  h/o sore throat 1 weeks back. BIRTH HISTORY:  Child was born at term by normal vaginal delivery  No H/o PNA  Antenatal, prenatal, postnatal period was uneventful.
  • 7. Feeding history Child was on family diet . IMMUNIZATION HISTORY: Completely Immunized . DEVELOPMENT HISTORY: Age appropriate. FAMILY HISTORY: 2nd issue of non consanguineous parents No family member has such type of disease
  • 8. Socioeconomic history Father: Businessman Mother: Housewife Lives in pacca house. drinks tube well water and use sanitary latrine
  • 9. General examination Appearance: ill looking, conscious; co-operative ,lying in supine position i/v cannula in situ. Afebrile, anemia: mildly pale Jaundice: absent Cyanosis: Absent Edema: Absent Dehydration: Absent clubbing: absent Leuconychia: absent Koilonychia :absent
  • 10. General examination (Cont)  Vital sign:  Temp: Normal  RR: 26 /min  HR: 90 b/min  BP : 90/50 mm of Hg (below 50th persentile)  BCG Mark: Present  No lymphadenopathy  Ear nose throat: normal  Sign of meningeal irritation: absent  Bony tenderness :absent
  • 11. General examination (Cont)  Skin survey: Maculopapular rash present on the extensor surface of the both legs, buttock,trunk,back of the chest of varying size and shape.redish in colour ;rashes are palpable ,not blanced on pressure and non tender.  Diascopic test : Negative  Anthropometry measurement:  Weight-26 kg WAZ(-1.2 sd)  Height-115 cm HAZ (-1sd)  WHZ(-1SD)  BMI: 19.6
  • 12. Abdominal EXAMINATION:  Abdomen:  Inspection: shape –normal Umbilicus centrally placed and inverted. No visible peristalsis , mass or scar mark.  Palpation: tenderness :present at periumbilical region. No organomegaly present.  Percussion: fluid thrill and Shifting dullness – absent  Auscultation: bowel sound present External genitalia-normal
  • 13.  NERVOUS SYSTEM: Higher psychic function: intact Cranial nerves: intact Motor function: intact Sensory function: intact Co ordination: present  PRECORDIUM EXAMINATION: Shape of precordium: normal no visible apical impulse apex beat: left 5th intercostal space medial TO mid clavicular line
  • 14.  Thrill: absent Heart rate: 90b/min; regular in character  Heart sound: 1st and 2nd heart sound were audible in all four cardiac areas  Murmur: absent  CHEST EXAMINATION:  no chest deformity  respiratory/rate: 26b/min  breath sound vesicular  no added sound
  • 15.  OTHER SYSTEMIC EXAMINATION REVEALED NO ABNORMALITY.
  • 16. SALIENT FEATURE:  Tasnim ,6years ,female child,2nd issue of non consanguineous parents hailing from hathazari admitted in CMOSHMC with the complaints of rash in different sites of the body for 6 days. which involving extensor surface of both lower limb ,buttock ,trunk and back of chest which was maculopapular , varying size and shape.rashes are palpable ,not blanced on pressure and non tender,reddish in color. Periumbilical pain for 3 days and no orgalomegaly present .
  • 17. SALIENT FEATURE(Contd) There was no history of joint pain, joint swelling, epistaxis, gum bleeding, melena,hematuria no history of taking any offending drugs, exposure to ionizing radiation, on examination tasnim was ill looking afebrile mildly pale, vitals are normal. No bony tenderness present , BSUA was nil BCG mark was present, anthropometrically well thriving . other systemic examination revels no abnormality.
  • 18. Provisional diagnosis  Henoch schonlein purpura(HSP)
  • 19. DIFFERENTIAL DIAGNOSIS:  ITP (immune thrombocytopenic purpura)  Acute leukemia  Aplastic anaemia 
  • 20. Investigations: CBC : Hb% 10g/dL ESR : 03 mm fall in 1st hour RBC : 5.12 million /cmm WBC : 10.57x 10 /cmm Platelet : 340,000/cmm Neutrophils : 57% Lymphocytes : 34% Eosinophils : 05% Monocytes : 04% Basophils: OO%
  • 21.  Red cell indices:  Pcv:42.3  MCV:82.6  MCH:27.3  MCHC:33  RDW:12.2%
  • 22. Urine routine examination:  Color:straw  Appearance:clear  Albumin:nill  Pus cell:6-8 pus cell  RBC:nill  Cast:  Hyaline:nill  Granular :nill  RBC:nill
  • 23. Investigation:  Serum creatinin:o.5mg/dl  Serum electrolyte:  Na+:146mmol/l  K+:4.2mmol/l  Cl:106mmol/l  hCO3:24mmol/l
  • 24. Ultasonography of whole abdomen :  Mild thickening of bowel wall in right lumbar region  Partially contracted gall bladder
  • 25. Treatment  Counseling about the disease  Maintenance of fluid and nutrition  Tab paracetamol500 mg  2/3rd +0+2/3rd  Tab cortan 10mg  1+0+1
  • 26. Prognosis  Excellent  15-60% have 1 or more recurrence  Chronic disease develops in 1-2 %  <5% HSP nephritis have ESRD  Long term prognosis depend son severity and duration of GIT or renal involvement
  • 27. Follow -up  Blood pressure monitoring  Bed side heat coagulation test  Intake output chart  Vital sign:  After discharge f/up upto 4wk but it will be recurrence within 4-6 month