HemaCare is a leading provider of apheresis products and services for biomedical research and cellular therapy. They have over 39 years of experience in blood collection and banking. They provide apheresis collections and human-derived blood components for preclinical and clinical applications such as biologics, immunotherapy, and cell therapy. HemaCare has established collection centers across the US that follow standardized protocols to optimize cell collection. They can customize collections based on factors like donor age, gender, and HLA type. HemaCare offers fresh and cryopreserved leukopaks as well as serum-free biopreservation media to maintain cell viability for shipping and storage.

1. HemaCare®
Product
Comprehensive Products & Services
for BioResearch & Cellular Therapy
2017

2. HemaCare: Leading Provider of Apheresis Products,
Blood Cells, & Apheresis Collection Services
• Market leader
– 250,000 apheresis procedures
– Over 39 years experience in blood collection and
banking
• Apheresis collections & human‐derived blood
components
– Preclinical & clinical applications
• Biologics
• Immunotherapy
• Cell therapy
• Assay development
• Medical devices
• Support preclinical research, clinical studies from
Phase I to Phase III, & commercialization
– Recognized by Dendreon as a top apheresis
collection performer for PROVENGE® cell therapy
Headquarters
Los Angeles, California

3. HemaCare Quality Advantage:
Our Donors Make the DIFFERENCE
Highly Characterized Donor Database
•We know our donors
 Recall donors / repeat collections
•They are qualified & tested for each donation
 Qualification, serological, & infectious testing performed
•We can recruit donors for specific investigator needs
 Age, gender, height, weight, ethnicity
 Medical history – vaccinations, diet, family history
 Lifestyle characteristics
 HLA type
 HIV, HepA, HepB, CMV testing
All donors are qualified per FDA regulations & IRB‐approved informed consent.

4. Apheresis Collection
The HemaCare Advantage
• Established collection center
• Rapidly add new centers as needed
• Standardized protocols & procedures across all
sites
• 24/7/365 support from clinical, logistics,
regulatory, & training experts
• Single point of contact
• Ability to optimize cell collection by controlling & qualifying the apheresis
processes based on cGMP & cGTP principles
• Use of clinical‐grade, serum‐free, protein‐free preservation media such as
HypoThermosol® & CryoStor® enables worldwide shipment of fresh or frozen
cellular products, extending shelf‐life of cells

5. Apheresis Collection‐
State of the art technology
• Based upon unique centrifugal technology
• Allows for distinct separation of whole blood plasma‐red blood cells‐white blood cells
• Selected removal of targeted components into collection bag
• Return remaining blood components to the donor
Terumo Optia
COBE Spectra
Industry standard
>20 years

6. HemaCare High Quality Leukapheresis Raw Material
Full Leukopak Count (x106) ±
SD
Total Nucleated Cells 14,400 550
Mononuclear Cells 12,100 600
n= 1,202 leukapheresis products

7. Fresh or Frozen Leukopak‐ unique offering
• HemaCare is the only provider of cryopreserved leukopak
– Use on demand
– Multiple portions for use at different times
– High recovery and viability
– Desirable for allogeneic cell therapy development, or cell
expansion protocols

8. Biopreservation Media
Success in the regenerative medicine, biobanking, and drug discovery
industries depends on the shelf life and viability of cells, tissues, and organs
designated for research or clinical applications.
CryoStor®
Pre-formulated with 2, 5, 10%, or
a custom volume of USP-grade
DMSO, CryoStor yields superior
post-thaw cell viability,
recovery, and function. Serum-
free and protein-free!
HypoThermosol®
Protein-free, serum-free
hypothermic storage media are
designed for maximum shelf life
and shipping stability at 2-8°C.

9. Thank You!
Visit us at www.hemacare.com