The document summarizes the past, present, and future of heart failure treatment. In the past (1950s-1970s), treatment focused on rest, sodium restriction, and drugs like digitalis and diuretics. Currently (2000s), guidelines recommend optimal medical therapy including ACE inhibitors, ARBs, beta-blockers, diuretics, and devices like ICDs, CRT, and LVADs which have improved outcomes. The future holds promise for gene and cell-based therapies, left ventricular assist devices, and prevention through understanding of genetic factors influencing heart failure.