Hadoop is an open-source software framework for distributed storage and processing of large datasets across clusters of computers. It uses MapReduce as a programming model and HDFS for storage. The document provides an overview of key Hadoop concepts including MapReduce terminology, the job launch process, mappers, reducers, input/output formats, and running Hadoop jobs on a cluster. It also discusses using Hadoop Streaming to run MapReduce jobs with any executable and submitting jobs to a GridEngine cluster.