The document discusses technologies of the future and exponential growth. It introduces the Department of Engineering at Aarhus University, which aims to educate outstanding engineers and perform research. It then covers several technologies being researched at the university including multi-core processors, photonic chip design, brain-computer interfaces, renewable energy systems, biomaterials, and single-cell analysis techniques. Computational power is enabling advances in these fields.
Growth Opportunities in Aeronautical and Mechanical Engineering By ATOA Scientific Technologies, Multiphysics CAE simulation solution provider, Future of Aeronautical and Mechanical Engineering
During the 9th “International Advanced Battery Power Conference” Klaus Eberhardt, Technology
Manager Battery and PV, ATF, presented our focus on cost-effective Li-Ion battery factories. The
conference took place from April 10-11, 2018 in Münster/Germany.
The expected growth in the battery industry will require numerous new factories around the globe. There is a clear trend that the battery manufacturing follows the automotive manufacturing: Closer to the customer, regulative requirements and safety aspects are the key drivers. Adequate sized battery manufacturing facilities are the prerequisite for achieving the required cost target of 100 $/kWh for the battery cells.
In his presentation, Mr. Eberhardt discussed cost reduction
potentials for the factory through scaling effects as well as smart
building concepts.
The role of engineering providers in successful industrialization of bio base...M+W Group
There are several examples of uses for a range of biologically-based products that are currently being developed. Even though crude oil has historically been used as a raw
material in numerous everyday objects, renewable raw materials can now provide an alternative to crude-oil-based industrial production thanks to industrial biotechnology. M+W Central Europe GmbH's Specialty Chemicals Unit supports such initiatives and projects
through feasibility studies, plant and process simulations, de-bottlenecking measures and other
engineering services, such as technology transfer and operationalization.
Engineering service providers play an important role in the successful industrialization of biobased
products. Dr. Anton Volkov, Lead Process Engineer for Industrial Biotechnology, held a talk on this subject, titled, "The Role of Engineering Providers in Successful Industrialization of
Bio-Based Products" where he examined how process innovation and technology can help manufacturing sustainable and cost competitive bio-based and green innovations.
Civil Engineering and Urban Planning: An International Journal (CiVEJ)civejjour
Civil Engineering and Urban Planning: An International Journal (CiVEJ) is an open-access, peer-reviewed journal that publishes articles which contribute new results in all areas of the Civil Engineering and Urban Planning. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of Civil Engineering and Urban Planning. The goal of this journal is to bring together researchers and practitioners from academia and industry to focus on Civil Engineering and Urban Planning advancements, and establishing new collaborations in these areas. Original research papers, state-of-the-art reviews are invited for publication in all areas of Civil Engineering and Urban Planning.
Growth Opportunities in Aeronautical and Mechanical Engineering By ATOA Scientific Technologies, Multiphysics CAE simulation solution provider, Future of Aeronautical and Mechanical Engineering
During the 9th “International Advanced Battery Power Conference” Klaus Eberhardt, Technology
Manager Battery and PV, ATF, presented our focus on cost-effective Li-Ion battery factories. The
conference took place from April 10-11, 2018 in Münster/Germany.
The expected growth in the battery industry will require numerous new factories around the globe. There is a clear trend that the battery manufacturing follows the automotive manufacturing: Closer to the customer, regulative requirements and safety aspects are the key drivers. Adequate sized battery manufacturing facilities are the prerequisite for achieving the required cost target of 100 $/kWh for the battery cells.
In his presentation, Mr. Eberhardt discussed cost reduction
potentials for the factory through scaling effects as well as smart
building concepts.
The role of engineering providers in successful industrialization of bio base...M+W Group
There are several examples of uses for a range of biologically-based products that are currently being developed. Even though crude oil has historically been used as a raw
material in numerous everyday objects, renewable raw materials can now provide an alternative to crude-oil-based industrial production thanks to industrial biotechnology. M+W Central Europe GmbH's Specialty Chemicals Unit supports such initiatives and projects
through feasibility studies, plant and process simulations, de-bottlenecking measures and other
engineering services, such as technology transfer and operationalization.
Engineering service providers play an important role in the successful industrialization of biobased
products. Dr. Anton Volkov, Lead Process Engineer for Industrial Biotechnology, held a talk on this subject, titled, "The Role of Engineering Providers in Successful Industrialization of
Bio-Based Products" where he examined how process innovation and technology can help manufacturing sustainable and cost competitive bio-based and green innovations.
Civil Engineering and Urban Planning: An International Journal (CiVEJ)civejjour
Civil Engineering and Urban Planning: An International Journal (CiVEJ) is an open-access, peer-reviewed journal that publishes articles which contribute new results in all areas of the Civil Engineering and Urban Planning. The journal is devoted to the publication of high quality papers on theoretical and practical aspects of Civil Engineering and Urban Planning. The goal of this journal is to bring together researchers and practitioners from academia and industry to focus on Civil Engineering and Urban Planning advancements, and establishing new collaborations in these areas. Original research papers, state-of-the-art reviews are invited for publication in all areas of Civil Engineering and Urban Planning.
Urban Futures for Architects - presented to Introduction to Architecture class at University of Kansas School of Architecture 22 Sep 2011. Topics covered:
1 How Do You Think About the Future? an overview of futures thinking, the change process
2 Big Urban Futures. demography, limited resources affecting 21st c cities
3 Architecture, Language and You. Places you can see the future today
Cindy Frewen, architect/blogger and Shelly Kramer, PR/blogger presented benefits of social media for architects and architectural firms. Marketing, recruiting, advocacy, and thought leadership were covered, including the use of various platform, strategies, example corporate strategies, and analytics.
Architects Who Blog: Connecting Online for Influencing, Educating, and Inspir...Cindy Frewen, FAIA, PhD
Cindy Frewen, Bob Borson, and Jody Brown presented at the AIA national convention in Washington DC on social media for architects, especially blogging, tweeting, linked in, and facebook.
5/13/14 Webinar presented by Ektron's Bob Canaway, VP of Marketing and Megan Menesale, Sr. Product Marketing Manager on the Ektron Content Marketing Platform (CMP), which enhances acquisition of customers; helps drive leads; and increases customer engagement
Opportunities and challenges in printed electronics productionQuad Industries
Printed electronics represents an enormous potential in a world of interconnected appliances. But there is still a large gap between the technology that is available and the potential for real-life applications. “That’s why we are focusing so strongly on intensive collaboration with our customers,” says Wim Christiaens, R&D director at Quad Industries.
Software Sustainability: The Challenges and Opportunities for Enterprises and...Patricia Lago
This is the opening keynote presentation to the 14th IFIP WG 8.1 Working Conference on the Practice of Enterprise Modeling (PoEM) 2021. See at https://poem2021.rtu.lv/program
Mechanical engineering video lectures for e learningMagic Marks
Mechanical Engineering is that discipline of engineering that covers the broadest scope of study. Many different areas of study are included in Mechanical Engineering like energy, dynamics, vibration, combustion, robotics, fluid mechanics and manufacturing processes among others.
Electroma Department of Electronics and communication EngineeringIIMTGroupofColleges
Department of Electronics and communication of IIMT College of Engineering organized various activities like Science Project Fair, Faculty Development.
Presentation of KLEEMANN Lifts and the COMPOSITION Project by Aggelos Papadopoulos, Technical Services Manager at Kleemann Lifts. The presentation was held at the IoT Innovation Days held at Fraunhofer FIT in Sankt Augustin, Germany.
Urban Futures for Architects - presented to Introduction to Architecture class at University of Kansas School of Architecture 22 Sep 2011. Topics covered:
1 How Do You Think About the Future? an overview of futures thinking, the change process
2 Big Urban Futures. demography, limited resources affecting 21st c cities
3 Architecture, Language and You. Places you can see the future today
Cindy Frewen, architect/blogger and Shelly Kramer, PR/blogger presented benefits of social media for architects and architectural firms. Marketing, recruiting, advocacy, and thought leadership were covered, including the use of various platform, strategies, example corporate strategies, and analytics.
Architects Who Blog: Connecting Online for Influencing, Educating, and Inspir...Cindy Frewen, FAIA, PhD
Cindy Frewen, Bob Borson, and Jody Brown presented at the AIA national convention in Washington DC on social media for architects, especially blogging, tweeting, linked in, and facebook.
5/13/14 Webinar presented by Ektron's Bob Canaway, VP of Marketing and Megan Menesale, Sr. Product Marketing Manager on the Ektron Content Marketing Platform (CMP), which enhances acquisition of customers; helps drive leads; and increases customer engagement
Opportunities and challenges in printed electronics productionQuad Industries
Printed electronics represents an enormous potential in a world of interconnected appliances. But there is still a large gap between the technology that is available and the potential for real-life applications. “That’s why we are focusing so strongly on intensive collaboration with our customers,” says Wim Christiaens, R&D director at Quad Industries.
Software Sustainability: The Challenges and Opportunities for Enterprises and...Patricia Lago
This is the opening keynote presentation to the 14th IFIP WG 8.1 Working Conference on the Practice of Enterprise Modeling (PoEM) 2021. See at https://poem2021.rtu.lv/program
Mechanical engineering video lectures for e learningMagic Marks
Mechanical Engineering is that discipline of engineering that covers the broadest scope of study. Many different areas of study are included in Mechanical Engineering like energy, dynamics, vibration, combustion, robotics, fluid mechanics and manufacturing processes among others.
Electroma Department of Electronics and communication EngineeringIIMTGroupofColleges
Department of Electronics and communication of IIMT College of Engineering organized various activities like Science Project Fair, Faculty Development.
Presentation of KLEEMANN Lifts and the COMPOSITION Project by Aggelos Papadopoulos, Technical Services Manager at Kleemann Lifts. The presentation was held at the IoT Innovation Days held at Fraunhofer FIT in Sankt Augustin, Germany.
A conference on computer science will not only improve your perspective over the said tech but also will keep you updated over the recent advancements on the same and at the same time will give you ample opportunity to represent your views, satisfy your queries and will give you a platform to showcase your ideas.
Surface Ventures: What Exponential Growth of Technology means for Tribolog...Tomasz Liskiewicz
Knowledge grows exponentially. The more we know, the greater our ability to learn and the faster we expand our knowledge base. The growth of knowledge fuels the growth of technology, with each new scientific discovery becoming a tool with which novel technologies are invented. It might be difficult to appreciate and accept the fact of exponential growth, as human perception is linear. Our brains have linear expectations, because that has always been the case. However, it has been postulated, that we are currently “on the knee” of the exponential growth of technology curve. As a result, technology progresses so fast, that the past no longer looks like the present, and the present is nowhere near how the future will look like. Materials science will play a key role in enabling future technologies, and we are in the midst of a materials science revolution that will impact every industry. Today, materials scientists are engineering smart, novel materials and functional surfaces with advanced properties well beyond state-of-the-art. Novel materials mean breakthrough opportunities in medicine, energy generation, transportation, consumer electronics, and high value manufacturing. This perspective talk discusses the current opportunities and future challenges for the protective and tribological coatings in the context of exponential growth of technology.
Level up your career with a Post Master's Degree in C-ITS (Connected Vehicles)Caroline HANRAS
You are interested in the high tech field of Connected cars and wish to take your career to the next level? The Post Master's degree may be the right option for you!
EURECOM's Post Master's degree offers the necessary knowledge required by engineers and managers to design connected cars / connected mobility applications and the related mechanisms to understand the innovations and seize the unique opportunities of the booming Vehicular Communications industry.
SmartBrains An Indian government authorize Training center offer various types of skill and development course in various cities in India. Our head office at noida U.P.
SmartBrains An Indian government authorize Training center offer various types of skill and development course in various cities in India. Our head office at Noida U.P.
Hybrid optimization of pumped hydro system and solar- Engr. Abdul-Azeez.pdffxintegritypublishin
Advancements in technology unveil a myriad of electrical and electronic breakthroughs geared towards efficiently harnessing limited resources to meet human energy demands. The optimization of hybrid solar PV panels and pumped hydro energy supply systems plays a pivotal role in utilizing natural resources effectively. This initiative not only benefits humanity but also fosters environmental sustainability. The study investigated the design optimization of these hybrid systems, focusing on understanding solar radiation patterns, identifying geographical influences on solar radiation, formulating a mathematical model for system optimization, and determining the optimal configuration of PV panels and pumped hydro storage. Through a comparative analysis approach and eight weeks of data collection, the study addressed key research questions related to solar radiation patterns and optimal system design. The findings highlighted regions with heightened solar radiation levels, showcasing substantial potential for power generation and emphasizing the system's efficiency. Optimizing system design significantly boosted power generation, promoted renewable energy utilization, and enhanced energy storage capacity. The study underscored the benefits of optimizing hybrid solar PV panels and pumped hydro energy supply systems for sustainable energy usage. Optimizing the design of solar PV panels and pumped hydro energy supply systems as examined across diverse climatic conditions in a developing country, not only enhances power generation but also improves the integration of renewable energy sources and boosts energy storage capacities, particularly beneficial for less economically prosperous regions. Additionally, the study provides valuable insights for advancing energy research in economically viable areas. Recommendations included conducting site-specific assessments, utilizing advanced modeling tools, implementing regular maintenance protocols, and enhancing communication among system components.
Welcome to WIPAC Monthly the magazine brought to you by the LinkedIn Group Water Industry Process Automation & Control.
In this month's edition, along with this month's industry news to celebrate the 13 years since the group was created we have articles including
A case study of the used of Advanced Process Control at the Wastewater Treatment works at Lleida in Spain
A look back on an article on smart wastewater networks in order to see how the industry has measured up in the interim around the adoption of Digital Transformation in the Water Industry.
NO1 Uk best vashikaran specialist in delhi vashikaran baba near me online vas...Amil Baba Dawood bangali
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Cosmetic shop management system project report.pdfKamal Acharya
Buying new cosmetic products is difficult. It can even be scary for those who have sensitive skin and are prone to skin trouble. The information needed to alleviate this problem is on the back of each product, but it's thought to interpret those ingredient lists unless you have a background in chemistry.
Instead of buying and hoping for the best, we can use data science to help us predict which products may be good fits for us. It includes various function programs to do the above mentioned tasks.
Data file handling has been effectively used in the program.
The automated cosmetic shop management system should deal with the automation of general workflow and administration process of the shop. The main processes of the system focus on customer's request where the system is able to search the most appropriate products and deliver it to the customers. It should help the employees to quickly identify the list of cosmetic product that have reached the minimum quantity and also keep a track of expired date for each cosmetic product. It should help the employees to find the rack number in which the product is placed.It is also Faster and more efficient way.
Sachpazis:Terzaghi Bearing Capacity Estimation in simple terms with Calculati...Dr.Costas Sachpazis
Terzaghi's soil bearing capacity theory, developed by Karl Terzaghi, is a fundamental principle in geotechnical engineering used to determine the bearing capacity of shallow foundations. This theory provides a method to calculate the ultimate bearing capacity of soil, which is the maximum load per unit area that the soil can support without undergoing shear failure. The Calculation HTML Code included.
Saudi Arabia stands as a titan in the global energy landscape, renowned for its abundant oil and gas resources. It's the largest exporter of petroleum and holds some of the world's most significant reserves. Let's delve into the top 10 oil and gas projects shaping Saudi Arabia's energy future in 2024.
1. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGEAARHUS
UNIVERSITY
DEPARTMENT OF ENGINEERING
AU
TECHNOLOGIES
OF THE FUTURE
EXPONENTIAL GROWTH
2. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
DEPARTMENT OF ENGINEERING
To Educate more Outstanding Engineers on All Levels
To Perform Engineering Science Research at the Highest International Level
Learn about us – follow the link.
3. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
EXPONENTIAL GROWTH
An analysis of the history of technology shows that technological change is exponential,
contrary to the common-sense “intuitive linear” view.
The exponential function: C is the initial amount. t is the time period.
(1 + r) is the growth factor, r is the growth rate.
y = C (1 + r) t
4.
5.
6. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
DEPARTMENT OF ENGINEERING
To Educate more Outstanding Engineers on All Levels
To Perform Engineering Science Research at the Highest International Level
Associate Professor Martijn J. R. Heck
7. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
• MULTI-CORE processors allow for the continuous scaling of Moore’s Law.
• Because they overcome bottlenecks of heat dissipation and data synchronization.
• Currently: 80 cores are at the high end. It is expected that the number of cores will
increase to around one hundred in the next few years and multiple hundreds by 2020.
• The maximum number of cores is expected to be around a thousand cores.
• Heck’s group is Developing Chip Layouts which incorporate
Optical Sources seaking further improvements in Performance
and Energy consumption.
ENG ECE: PHOTONICS GROUP
Heck & Bowers, 2014 Journal of Selected Topics in Quantum Electronics
8. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
New Chip Designs - new paradigms
• Optical approaches as by Heck et al.
• Chips are primarely 2D design and it make sence to use the third dimension
• Mimicking the Brain and its design
The impact of computers will become…
COMPUTATIONAL POWER WILL
CONTINUE TO INCREASE
9. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
Most computers will NOT be computers.
How many electric motors do you have in your home?
How many did you buy as electric motors?
I control several computers, but most computers I control
are embedded in cars, remote controls, refrigerators, etc.
We will see Smart, or apparently Intelligent Products.
Intels computer on stick, 2015
10. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
DEPARTMENT OF ENGINEERING
To Educate more Outstanding Engineers on All Levels
To Perform Engineering Science Research at the Highest International Level
11. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
THE CAR AS AN EXAMPLE
TWT in Germany is one of the project’s case companies:
They helps car-manufacturers (BMW / Audi) with simulations and models of prototypes.
Peter Gorm Larsen:
A car built around the turn of the millennium, didn’t contain many computers controlling its functions.
A modern car, involves more than 100 different small computers controlling everything from the keys and brakes to
cruise control and automatic parking functionality.
It is clear that this development provides the car industry with completely new challenges in both the development and
the test stages.
What do you do when the many computers need to talk to each other?
How do you ensure that they adapt as well as possible to the context in which they will be used?
12. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
INTELLIGENCE THROUGH ALGORITHMS
Agricultural machinery of the future needs to communicate
Resources and time to be saved during harvesting
if the different field operations and harvesting
equipment can be coordinated in a more
optimal way
13. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
CONSEQUENCE
With increasing computational power, system complexity, and with improved algorithms
technology will become responsive and demonstrate more complex behaviour:
This AUDI autonomously drove across the US
14. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
DEPARTMENT OF ENGINEERING
To Educate more Outstanding Engineers on All Levels
To Perform Engineering Science Research at the Highest International Level
Preben Kidmose
15. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
INTERFACING WITH THE BRAIN
Preben Kidmose builds this in-the-ear EEG device:
It is a Brain-computer interface developed with
micro-computers and advanced algorithms that can
interpret electrical activity in the brain cells and
thereby reveal some mental states
An insulin shock detector is one of the many potential applications of the technology
The device will protects diabetes patients. Small electrodes measure electrical brain
signals and warn the patient if their blood sugar drops to a critically low level
16. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
DEPARTMENT OF ENGINEERING
To Educate more Outstanding Engineers on All Levels
To Perform Engineering Science Research at the Highest International Level
Rune Hylsberg Jakobson
17. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
FLEXIBLE USE OF ELECTRICITY NEEDED?
Problem: Solar and wind energy is fluctuating. Consumer demand is fluctuating
How to minimize a surplus of electricity production & reduce emission of greenhouse gases?
Develop an information system placing decision at the consumer level and balance
consumers needs and opportunities given to the consumer with actual energy production
capabilities
Use data analysis to improve understanding – learn - when, how much and in which way
energy is used in households
Develop algorithms that will informing consumers of alternative choices
18. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
CONSEQUENCE
With increasing computational power, and with the human brain in the loop
our decision process change
One impressive technology recently
demoed is Skype Translator
It provide live translation from
one language to another:
This is now, what happens with further
computational power available?
19. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
HYBRID THINKING
Ray Kurzweil elaborated in a
recent TED talk on what happens
when you combine:
› Brain machine interfaces
› Communication networks
› Cloud computing
› Increased computational power
20. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
Martijn Heck: “You only succeed if you can do it well. If you cannot do it well, basically you
have a useless technology”.
This attitude, our curriosity drives evolution. Like the chip design evolving through paradigms.
It is the Evolution Process which is Exponential, not only Moore’s law.
Miniaturization of technology is also an evolution process. The fundamental concepts driving
this is our ability to apply Materials and Control their Arrangement.
TECHNOLOGICAL DEVELOPMENT IS AN
EVOLUTION
21.
22. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
US Initiative by Barack Obama, 2011
For many years, the United States has been a dominant player in the discovery of
transformative materials that are the basis of entirely new products and industries, yet the
time lag between discovery of advanced materials and their use in commercial products
can be 20 years or more.
At the heart of MGI is the Materials Innovation Infrastructure
› Framework for seamlessly integrated Experiments, Computation, Theory
› Access to Digital Data
› A Well-Equipped Workforce
MATERIALS GENOME PROJECT (MGI)
23. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
DEPARTMENT OF ENGINEERING
To Educate more Outstanding Engineers on All Levels
To Perform Engineering Science Research at the Highest International Level
Assoc. Prof. Søren P. Madsen
24. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
IMPROVING SOLAR ENERGY
PRODUCTION
Søren Madsen is building Mathematical Models of the Nano Material and its Layout,
solving the Electro Magnetic field equations to get an idea of Electron Transport in the
Titanium dioxide layer as Sun Light hits the Surface
The Material Development Cycle is reduced as a
high number of variation of Silver nanoparticle
shapes and layout is virtually tested prior to
production in the iNANO clean room
We need computational power to test more
advanced material systems
Johannsen et al. 2015 in Applied Physics Letters
25. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
… and you get a self powered camera:
The pixel’s photodiode can be used to not only
measure the incident light level, but also
convert the incident light into electrical energy
MERGING SOLAR ENERGY PRODUCTION
WITH INTEGRATED ELECTRONICS
Nayar, S.K., Sims, D.C. & Fridberg, M., 2015 Towards Self-Powered Cameras.
Proceeding of the International Conference on Computational Photography ICCP.
26. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
DEPARTMENT OF ENGINEERING
To Educate more Outstanding Engineers on All Levels
To Perform Engineering Science Research at the Highest International Level
27. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
Microstructure from 3D print:
• Shielding of the nanostructure because of the large differences in
stiffness needed for transduction and native tissue
• Anatomical correct shapes to fit the site of implant
Nano: Micro:Same material
Combined into a single component
Nanostructure:
• Bioactivity induced mechanically
and chemically.
BIOMATERIAL GUIDE CELLS TO BUILD TISSUE
30. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
Functionalized Scaffolds for Tissue Engineering
We have established methods to build 3D scaffolds in a manner that enables us to synthesize
designs which include functions within the 3D scaffold at all length scales from macro to nano:
Advanced functionalization is needed if a scaffold is to succeed with correct tissue regeneration. Regenerated tissue must
include inherent functions realized in native tissue. Thus, an integrated design approach is needed.
Anatomical correct
shapes to fit the site of
implant made by the
surgeon.
Molecular surface modifications
to improve cellular signaling
and / or nanostructural interaction.
Artificial vascularisation
to improve perfusion
and cultivation of thick
tissues.
Use of composites to
tailor scaffold morphology
and improve host integration.
mm μm nm
Particles
Fibers Platelet
Porous
31. 3D Characterization
Nygaard et al. in
Biotech. & Bioeng.
The history of LevOss – a journey of innovation
AcademicCommercial
2006 20132012 2014 2015 2020
Filing of IP
Three-dimentional
Nanostructured Hybrid
Scaffold and
Manufacture Thereof.
Patent nr.
PCT/DK2010/050167
Spun out from
University
Jan 2012 with Seed
investment from
SEED capital
2010
HTF Grant
2 M Euro
GMP partner and in
vivo models
Closure of next
Seed Round
Invitation for X M Euro
Building of syndicate
Large animal model
Mini pig study
Weak translation of rabbit data
in larger animals
Multiple tissues
Biomarkers by gene
expression
Scaffold
Production
Chen et al. in
Acta Biomaterialia
MQUL Collaboration
Drug delivery system for OA
MIT Collaboration
Microtia tissue engineering
New SAB
Prof Mats Brittberg
Prof Verdonk
Q3 2015
Mechanotransduction
hypothesis – cartilage ?
Biomarkers by gene expression
AU Thesis
Mechanics of Stem Cells
Filing new IP
Injectable
PA/2013 70759
Bone Repair
Jensen et al. in
J. Biomed. Mater. Res.
BREAK THROUGH
PAPER
ENGLER ET AL. 2006 IN CELL
MATRIX ELASTICITY DIRECTS STEM
CELL LINEAGE SPECIFICATION
Nanoporous
Deformations
Nygaard et al. on
Invited Biomechanics Workshop
AU Thesis
Cartilage signaling
siRNA to Stem
Cells
Andersen et al. in
Molecular Therapy
Vascularization
Wittenborn et al. in
J Magn Reson Imaging
Nanostructured Scaffold
Bjerre et al. on
ORS 55th Annual Meeting
Cartilage Repair
Christensen et al. in
Knee Surg. Sports Trauma. Arthroscopy
B.Sc Course Design of Medical Devices
M.Sc Course Tissue Engineering (first in Denmark)
3D Print with RNA
Andersen et al. in
Adv. Func. Materials
32. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
DEPARTMENT OF ENGINEERING
To Educate more Outstanding Engineers on All Levels
To Perform Engineering Science Research at the Highest International Level
33. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
FOCUSING ON A SINGLE CELL
Peter Kristensen is able to find the few
cancer cells between billions of healthy
cells in a blood sample
The key is a small chip that is able to bind the
cancer cells on its surface using antibodies
Through selection (image processing) that single cell of interest is
identified and the surroundings are destroyed with UV light
Access to single cells will enhance our understanding of disease
progression and how cell functions and interact
34. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
DEPARTMENT OF ENGINEERING
To Educate more Outstanding Engineers on All Levels
To Perform Engineering Science Research at the Highest International Level
Associate Professor Xuping
Zhang
35. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
ROBOTIC SINGLE-CELL HANDLING
Xuping Zhang builds a robot
that works within a microscope
With it, he can handle cells:
pick-and-place, positioning,
rotating, sorting, patterning,
identification, inspection,
isolation, injection, etc.
Specifically he works on an intra cytoplasmic sperm injection (ICSI) system.
36. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
DRUG DELIVERY
NANOCOMPOSITE DELIVER SIRNA TO STEM CELL AND CONTROL THEIR
DIFFERENTIATION
Andersen et al. 2010 Molecular Therapy 18 (11) 2018-2027
37. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
DRUG DELIVERY
NANOCOMPOSITE DELIVER SIRNA TO STEM CELL AND CONTROL THEIR
DIFFERENTIATION
Making bone and fat within the same material – in each side, solely by
delivering two different siRNA sequences to stem cells (hMSC):
Histological sections from the mouse stained with von Kossa (mineralization
appears black) and by immunohistochemistry for osteocalcin
(osteocalcin appears brown) Andersen et al. 2010 Molecular Therapy 18 (11) 2018-2027
38. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
MATERIALS ENGINEERING
BIOMATERIALS – SELF ASSEMBLY IN NATURE
Fratzl and Weinkamer (2007)
40. 24TH OF APRIL 2015
FD
HEAD OF MECHANICAL ENGINEERING
JENS VINGE
DEPARTMENT OF ENGINEERING
AARHUS
UNIVERSITYAU
DEPARTMENT OF ENGINEERING
To Educate more Outstanding Engineers on All Levels
To Perform Engineering Science Research at the Highest International Level
Learn about us – follow the link.
Morning – thank you for taking your time to show up.
My opportunity to let you know about a recent perspective on Technology and let become a bit more familiar with My Department of Engineering
I have taken the liberty to alter the language into English
We came to this organisation from international standards (Body of Knowledge) on how the Engineering Disciplines is established through history
It is combined with the fact coming from that it is people in our organisation who actually do the science.
The current computational power
The computational power to come
Passing the computational power of the brain in a mouse 2020 and humans some 2050 ?
Picture of the Intel Pentium chip
Can we continue to improve on this kind of technology, the densification of transistors?
We agree on that the computational power in computers will continue to grow as predicted.
And it will transcent the capability of the human brain to do calculations
Intel has rather impressively crammed in a quad-core Atom CPU, 32GB of storage and 2GB of RAM, along with a USB port, WiFi and Bluetooth 4.0 support and a mini-USB connector for power. It runs Windows 8.1.
What runs the in the computer is code, software. The smartness comes from the algorithms – the code.
The enabling step in building smart / intelligent products is profound integration of hardware and software.
http://www.telegraph.co.uk/finance/newsbysector/industry/engineering/11495706/Driverless-cars-to-create-320000-UK-jobs-and-save-2500-lives.html
Driverless cars to create 320,000 UK jobs and save 2,500 lives Britain will get huge economic boost from driverless cars which will also cut death toll on roads, new report predict.
Why don’t we see this AUDI on the streets? Because technology is being brought to marked along with comsumer adaptation and willingness to pay for features.
Self driving cars tend to make pasengers sick (12%)
One of the most complex systems that we know of is our brain.
Accumulating information on Energy comsumption and guide consumers in their behaviour.
we create a better balance between our electricity consumption and our electricity production from renewable energy sources.”
Live translation and live information support will change negotiations, lower barriers and improve conflict handling.
The transition towards hybrid thinking starts with the Google Glass and Apple Watch and once these technologies is combined with our knowledge on Medical Devices we will get to the hybrid thinking as presented here.
It will be great as a scientist in 2040 when my brain together with my exponential growing non-biological cloud brain crack problems.
Materials Genome Initiative National Science and Technology Council Committee on Technology Subcommittee on the Materials Genome Initiative
DECEMBER 2014
Here in Europe we do the same; we call it something else less coordinated, but the X-Ray facility in Lund is one example.
Ti O2 = Titanium dioxide
This is an example on how Materials Engineering and System Integration lead to innovation.
The continued miniturization provide improved sensors in our microscopes letting us see smaller details leading to improved processing – its an evolution
Materials Engineering harness computation power to predict materials behaviour during processing or in its final state
3D printing of the macro structure rely on Digital Manufacturing converting 3D geometry into physical shapes
Turn through a material investigating a single cells frozen while in the process of developing bone.
XTM Image from ESRF
How long time did it take me to make this image – approximately 2,5 years.
His chip works according to a simple principle. It contains a canal with fluid through which the patient’s blood is injected. There are special antibodies on the inner surface of the canal that are able to capture the cancer cells in the sample.
Cells are like Robots. From the Genome they are program using DNA. During the process of decoding DNA in actions, that the cell take, it splises the DNA into RNA as a natural process.
You can take advantage of this proces and deliver RNA directly into the cell using nanoparticles and program it.
BCL2L2 = Osteogenic (BONE)
TRIB2 = adipose (FAT)
Euplectella :
Not only as miniturization as shown here
But also with increase in system integration (complexity)
The Michigan Micro Mote is thought as sensor for medican devices, collecting information, proces it and transmitting response using its radio layer.
