This document provides tips for giving effective presentations. It discusses using the "onion model" to structure a presentation with the outer layers focusing on why the topic matters and the big picture, followed by what was done, and finally limiting details on how the work was done. It also recommends using the "assertion-evidence" template for slides, where the slide title makes an assertion and the body provides evidence. Finally, it lists some pet peeves about presentations, such as not reading text on slides out loud and overusing bullet points.
6. Ketogenic diet as supporting treatment
option in glioblastoma multiformae
7. Ketogenic diet as supporting treatment
option in glioblastoma multiformae
On a ketogenic diet, the liver produces ketone bodies, in
par9cular β-hydroxybuturate (BHB)
8. Ketogenic diet as supporting treatment
option in glioblastoma multiformae
BHB can cross the blood-brain barrier and serve as an
alterna9ve fuel for brain cells, replacing glucose
9. Ketogenic diet as supporting treatment
option in glioblastoma multiformae
A diet is ketogenic when carbohydrate intake falls below
20-50 gram/day while fat comprises ~80% of caloric
intake
10. Ketogenic diet as supporting treatment
option in glioblastoma multiformae
Glioblastoma mul9formae (GBM) needs glucose for
growth, and seems inhibited by the presence of BHB
11. Ketogenic diet as supporting treatment
option in glioblastoma multiformae
Several clinical trials are currently ongoing to determine
whether ketogenic diets can slow or inhibit GBM growth
28. Ketogenic diet as supporting treatment
option in glioblastoma multiformae
• On a ketogenic diet, the liver produces ketone bodies, in
par9cular β-hydroxybuturate (BHB)
• BHB can cross the blood-brain barrier and serve as an
alterna9ve fuel for brain cells, replacing glucose
• A diet is ketogenic when carbohydrate intake falls below
20-50 gram/day while fat comprises ~80% of caloric intake
• Glioblastoma mul9formae (GBM) needs glucose for
growth, and seems inhibited by the presence of BHB
• Several clinical trials are currently ongoing to determine
whether ketogenic diets can slow or inhibit GBM growth
29. Why eating eggs and bacon may cure
brain cancer
• Cancer is the leading cause of death in developed
countries
• Despite medical advances, most cancer treatments are
gruesome yet only moderately successful
• If we could prevent or treat cancer by a simple change in
diet, that would be awesome
• Increasing evidence links cancer to high-carbohydrate
diets (in par9cular sugar and starches)
• Ea9ng a high-fat, low-carb diet (like the Atkins diet) may
starve tumors of necessary glucose
• Ini9al trials with brain-cancer pa9ents have been
promising, and further trials are ongoing
51. The Department in numbers
• We have 36 faculty members
• Annual grant funding: $5M
– Funding agencies: NSF, NIH, ARO, ONR,
DARPA, DTRA, USDA
• Our faculty members supervise 112 graduate
students
– 69 EEB, 23 Plant Biology, 10 CMB, 10 other
• 20% of our graduate students receive external
fellowships
– 14 NSF GRFP, 1 NIH F31, 10 other
52. The Department in numbers
36faculty members
112
graduate students
69 EEB
23 PB
10 CMB
10 Other
20%students on external fellowships
14 NSF GRFP
1 NIH F31
10 Other
$5M
annual grant funding
NSF, NIH, ARO, ONR, DARPA, DTRA, USDA