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Giant Aneurysmal Bone Cyst 
11/1/2014 
Professor Freih Abuhassan - University 
of Jordan 1
Giant Aneurysmal Bone Cyst 
F.R.C.S.(Eng.), F.R.C.S.(Tr.& Orth.) 
Professor of Orthopaedics 
Professor Freih Abuhassan - University 
11/1/2014 2 
of Jordan
Patient profile: 
A 9-years old male child, MF, Overweight. 
Chief complaint: 
Progressive painless swelling of the 
right distal thigh of 14 m duration 
Referred to us on the 
17th Nov. 2008 
Professor Freih Abuhassan - University 
11/1/2014 3 
of Jordan
History of present illness: 
4th Sep. 2007, had pain in the distal femur 
after a fall while playing. 
Diagnosed as pathological fracture of 
the distal femur. 
Professor Freih Abuhassan - University 
11/1/2014 4 
of Jordan
4th Sep. 2007 
Professor Freih Abuhassan - University 
11/1/2014 5 
of Jordan
Treated by complete POP for 3 M 
4th Dec. 2007 
Professor Freih Abuhassan - University 
11/1/2014 6 
of Jordan
19th Jan. 2008 
Trivial trauma  Supracondylar distal 
femur fractures treated by POP for 
7 weeks 
Professor Freih Abuhassan - University 
11/1/2014 7 
of Jordan
19th Jan. 2008 
Professor Freih Abuhassan - University 
11/1/2014 8 
of Jordan
5th Mar. 2008 
Professor Freih Abuhassan - University 
11/1/2014 9 
of Jordan
Past medical history 
=History of two surgical biopsies with 
blood transfusion 
Diagnosis: Aneurysmal bone cyst 
Professor Freih Abuhassan - University 
11/1/2014 10 
of Jordan
Patient offered the following 
advices outside JUH 
1- Above Knee Amputation 
2- Resection and Joint replacement 
3- To be treated abroad 
Patient was wheel chair dependent 
since the start of treatment. 
Professor Freih Abuhassan - University 
11/1/2014 11 
of Jordan
Lesion contineued to grow 
6th June 2008 
Professor Freih Abuhassan - University 
of Jordan 
11/1/2014 12
26th Sep. 2008 
Professor Freih Abuhassan - University 
11/1/2014 13 
of Jordan
Physical examination: 
17th Nov. 2008 
General: no abnormality detected 
Right lower limb: 
= Diffuse swelling of the knee and lower thigh with 
10 cm diameter difference form the left thigh 
(firm, not tender, not pulsatile) 
=Decreased knee ROM due to the bulky swelling 
=Normal distal NV examination 
Professor Freih Abuhassan - University 
11/1/2014 14 
of Jordan
Professor Freih Abuhassan - University 
11/1/2014 15 
of Jordan
Professor Freih Abuhassan - University 
11/1/2014 16 
of Jordan
Professor Freih Abuhassan - University 
11/1/2014 17 
of Jordan
Laboratory investigation 
CBC 
KFT 
LFT 
ESR 
CRP 
All were Normal 
Professor Freih Abuhassan - University 
11/1/2014 18 
of Jordan
17th Nov. 2008 
Professor Freih Abuhassan - University 
11/1/2014 19 
of Jordan
Professor Freih Abuhassan - University 
11/1/2014 20 
of Jordan
Professor Freih Abuhassan - University 
11/1/2014 21 
of Jordan
Professor Freih Abuhassan - University 
11/1/2014 22 
of Jordan
Professor Freih Abuhassan - University 
11/1/2014 23 
of Jordan
Professor Freih Abuhassan - University 
11/1/2014 24 
of Jordan
Surgery at JUH 
19th Nov. 2008 
First stage 
Local curretage of the cyst + 
application of monoplanar external 
fixator + Circular Ex.Fix. (across 
the knee joint) Ilizarov Frame. 
Professor Freih Abuhassan - University 
11/1/2014 25 
of Jordan
Problems 
1- Difficult to apply Tourniquet 
2- Lateral Scar of previous surgery 
3-Soft bone (prolonged disuse) 
4-Extensive bleeding 
5-Overweight 
6-Residual defect after resection. 
Professor Freih Abuhassan - University 
11/1/2014 26 
of Jordan
Packing the cyst after surgery to stop 
bleeding. 
Received in the perioperative period 
= 5.5 L R/L 
= 4 U PRBC’s 
= 10 U FFP 
Role of anaesthetic team 
in the management 
Professor Freih Abuhassan - University 
11/1/2014 27 
of Jordan
=Transferred to the ICU and kept 
there till 24/11 
=Initially DIC W/up +ve 
=21st Nov. 2008 R/O pack 
Professor Freih Abuhassan - University 
11/1/2014 28 
of Jordan
Professor Freih Abuhassan - 
11/1/2014 29 
University of Jordan
Histopathology 
ABC 
Professor Freih Abuhassan - University 
11/1/2014 30 
of Jordan
Professor Freih Abuhassan - 
11/1/2014 31 
University of Jordan
Professor Freih Abuhassan - 
11/1/2014 32 
University of Jordan
Professor Freih Abuhassan - 
11/1/2014 33 
University of Jordan
Professor Freih Abuhassan - 
11/1/2014 34 
University of Jordan
16th Dec. 2008 
2nd stage Surgery 
= Under tourniquet, Anterior approach, 
Complete resection of the cyst. 
=Turbid hematoma was found inside 
the cavity. 
=Delay reconstruction of the bone 
defect till results of C&S. 
=Bone cement spacer was inserted. 
Professor Freih Abuhassan - University 
11/1/2014 35 
of Jordan
Professor Freih Abuhassan - 
11/1/2014 36 
University of Jordan
Professor Freih Abuhassan - 
11/1/2014 37 
University of Jordan
Cultures: no bacterial growth 
Gram stain: 
only WBC’s & RBC’s, no bacteria 
Professor Freih Abuhassan - University 
11/1/2014 38 
of Jordan
Reconstructive Procedure 
Professor Freih Abuhassan - University 
11/1/2014 39 
of Jordan
3nd stage Surgery 
23rd Dec. 2008 
1. Removal of Cement spacer 
2. Strut tibial autograft from the mid 
ipsilateral tibia, to femur and 
stabilized by long screws to the 
ilizarov frame. 
3. Application of ilizarov to tibia + 
bone marrow inserted. 
Professor Freih Abuhassan - University 
11/1/2014 40 
of Jordan
Professor Freih Abuhassan - University 
11/1/2014 41 
of Jordan
Professor Freih Abuhassan - University 
11/1/2014 42 
of Jordan
Professor Freih Abuhassan - University 
11/1/2014 43 
of Jordan
Professor Freih Abuhassan - 
11/1/2014 44 
University of Jordan
23rd Dec. 2008 Professor Freih Abuhassan - 
11/1/2014 University of Jordan 
45
Professor Freih Abuhassan - University 
11/1/2014 46 
of Jordan
Professor Freih Abuhassan - University 
11/1/2014 47 
of Jordan
5th Jan. 2009 
Admitted as a case popliteal fossa 
swelling to R/O organised hematoma 
U/S: no definite fluid collection but 
significant soft tissue edema. 
= Percutaneous evacuation of hematoma, 
=R/O Orthofix and application of long 
Ilizarov plate externally and fixed to the 
graft by Schanz screws 
Professor Freih Abuhassan - University 
11/1/2014 48 
of Jordan
Followed regularly in OPD 
Partial weight bearing was started 
in the on 21st Jan. 2009. 
Now FWB on crutches 
Professor Freih Abuhassan - University 
11/1/2014 49 
of Jordan
25th March 2009 
Professor Freih Abuhassan - 
11/1/2014 50 
University of Jordan
Professor Freih Abuhassan - 
11/1/2014 51 
University of Jordan
With Ilizarov family 
Professor Freih Abuhassan - 
11/1/2014 52 
University of Jordan
ABC 
In 1942, Jaffe and Lichtenstein 
first described ABC when they 
discovered "a peculiar blood 
containing cyst of large size. 
Professor Freih Abuhassan - University 
11/1/2014 53 
of Jordan
Benign Aggressive Bone 
TuLmoocar lly destructive yet do not 
metastasize or show malignant 
changes at a cellular levelcellular 
level 
ABC, GCT, CMF, 
Chondroblastoma, 
Osteoblastoma. 
Professor Freih Abuhassan - University 
11/1/2014 54 
of Jordan
ABCs represent 1%–2% of all 
primary bone lesions 
WHO 
Blood-filled spaces of variable 
size,separated by CT containing 
trabeculae of bone or osteoid 
tissue and osteoclast giant cells 
Professor Freih Abuhassan - University 
11/1/2014 55 
of Jordan
D.Dx 
Giant Cell tumour 
Aneurysmal bone cyst 
Telangiectatic osteosarcoma 
Secondary ABC –upto 35% of all ABCs 
Most commonly due to GCT (39%) 
Professor Freih Abuhassan - University 
11/1/2014 56 
of Jordan
No bone is immune 
11/1/2014 57
Giant Humerus ABC 
11/1/2014 Professor Freih Abuhassan - 58 
University of Jordan
Giant femur ABC 
Professor Freih Abuhassan - University 
11/1/2014 59 
of Jordan
Giant ABCs 
Professor Freih Abuhassan - 
11/1/2014 60 
University of Jordan
Treatment depends on 
site & size of the lesion. 
Local recurrence rate after 
classic surgical procedures 
(curettage and grafting) is about 
11.8%–30.8% 
Professor Freih Abuhassan - University 
11/1/2014 61 
of Jordan
Professor Freih Abuhassan - University 
11/1/2014 62 
of Jordan

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Giant aneurysmal bone cyst - البروفيسور فريح ابوحسان - اكياس العظام العملاقه

  • 1. Giant Aneurysmal Bone Cyst 11/1/2014 Professor Freih Abuhassan - University of Jordan 1
  • 2. Giant Aneurysmal Bone Cyst F.R.C.S.(Eng.), F.R.C.S.(Tr.& Orth.) Professor of Orthopaedics Professor Freih Abuhassan - University 11/1/2014 2 of Jordan
  • 3. Patient profile: A 9-years old male child, MF, Overweight. Chief complaint: Progressive painless swelling of the right distal thigh of 14 m duration Referred to us on the 17th Nov. 2008 Professor Freih Abuhassan - University 11/1/2014 3 of Jordan
  • 4. History of present illness: 4th Sep. 2007, had pain in the distal femur after a fall while playing. Diagnosed as pathological fracture of the distal femur. Professor Freih Abuhassan - University 11/1/2014 4 of Jordan
  • 5. 4th Sep. 2007 Professor Freih Abuhassan - University 11/1/2014 5 of Jordan
  • 6. Treated by complete POP for 3 M 4th Dec. 2007 Professor Freih Abuhassan - University 11/1/2014 6 of Jordan
  • 7. 19th Jan. 2008 Trivial trauma  Supracondylar distal femur fractures treated by POP for 7 weeks Professor Freih Abuhassan - University 11/1/2014 7 of Jordan
  • 8. 19th Jan. 2008 Professor Freih Abuhassan - University 11/1/2014 8 of Jordan
  • 9. 5th Mar. 2008 Professor Freih Abuhassan - University 11/1/2014 9 of Jordan
  • 10. Past medical history =History of two surgical biopsies with blood transfusion Diagnosis: Aneurysmal bone cyst Professor Freih Abuhassan - University 11/1/2014 10 of Jordan
  • 11. Patient offered the following advices outside JUH 1- Above Knee Amputation 2- Resection and Joint replacement 3- To be treated abroad Patient was wheel chair dependent since the start of treatment. Professor Freih Abuhassan - University 11/1/2014 11 of Jordan
  • 12. Lesion contineued to grow 6th June 2008 Professor Freih Abuhassan - University of Jordan 11/1/2014 12
  • 13. 26th Sep. 2008 Professor Freih Abuhassan - University 11/1/2014 13 of Jordan
  • 14. Physical examination: 17th Nov. 2008 General: no abnormality detected Right lower limb: = Diffuse swelling of the knee and lower thigh with 10 cm diameter difference form the left thigh (firm, not tender, not pulsatile) =Decreased knee ROM due to the bulky swelling =Normal distal NV examination Professor Freih Abuhassan - University 11/1/2014 14 of Jordan
  • 15. Professor Freih Abuhassan - University 11/1/2014 15 of Jordan
  • 16. Professor Freih Abuhassan - University 11/1/2014 16 of Jordan
  • 17. Professor Freih Abuhassan - University 11/1/2014 17 of Jordan
  • 18. Laboratory investigation CBC KFT LFT ESR CRP All were Normal Professor Freih Abuhassan - University 11/1/2014 18 of Jordan
  • 19. 17th Nov. 2008 Professor Freih Abuhassan - University 11/1/2014 19 of Jordan
  • 20. Professor Freih Abuhassan - University 11/1/2014 20 of Jordan
  • 21. Professor Freih Abuhassan - University 11/1/2014 21 of Jordan
  • 22. Professor Freih Abuhassan - University 11/1/2014 22 of Jordan
  • 23. Professor Freih Abuhassan - University 11/1/2014 23 of Jordan
  • 24. Professor Freih Abuhassan - University 11/1/2014 24 of Jordan
  • 25. Surgery at JUH 19th Nov. 2008 First stage Local curretage of the cyst + application of monoplanar external fixator + Circular Ex.Fix. (across the knee joint) Ilizarov Frame. Professor Freih Abuhassan - University 11/1/2014 25 of Jordan
  • 26. Problems 1- Difficult to apply Tourniquet 2- Lateral Scar of previous surgery 3-Soft bone (prolonged disuse) 4-Extensive bleeding 5-Overweight 6-Residual defect after resection. Professor Freih Abuhassan - University 11/1/2014 26 of Jordan
  • 27. Packing the cyst after surgery to stop bleeding. Received in the perioperative period = 5.5 L R/L = 4 U PRBC’s = 10 U FFP Role of anaesthetic team in the management Professor Freih Abuhassan - University 11/1/2014 27 of Jordan
  • 28. =Transferred to the ICU and kept there till 24/11 =Initially DIC W/up +ve =21st Nov. 2008 R/O pack Professor Freih Abuhassan - University 11/1/2014 28 of Jordan
  • 29. Professor Freih Abuhassan - 11/1/2014 29 University of Jordan
  • 30. Histopathology ABC Professor Freih Abuhassan - University 11/1/2014 30 of Jordan
  • 31. Professor Freih Abuhassan - 11/1/2014 31 University of Jordan
  • 32. Professor Freih Abuhassan - 11/1/2014 32 University of Jordan
  • 33. Professor Freih Abuhassan - 11/1/2014 33 University of Jordan
  • 34. Professor Freih Abuhassan - 11/1/2014 34 University of Jordan
  • 35. 16th Dec. 2008 2nd stage Surgery = Under tourniquet, Anterior approach, Complete resection of the cyst. =Turbid hematoma was found inside the cavity. =Delay reconstruction of the bone defect till results of C&S. =Bone cement spacer was inserted. Professor Freih Abuhassan - University 11/1/2014 35 of Jordan
  • 36. Professor Freih Abuhassan - 11/1/2014 36 University of Jordan
  • 37. Professor Freih Abuhassan - 11/1/2014 37 University of Jordan
  • 38. Cultures: no bacterial growth Gram stain: only WBC’s & RBC’s, no bacteria Professor Freih Abuhassan - University 11/1/2014 38 of Jordan
  • 39. Reconstructive Procedure Professor Freih Abuhassan - University 11/1/2014 39 of Jordan
  • 40. 3nd stage Surgery 23rd Dec. 2008 1. Removal of Cement spacer 2. Strut tibial autograft from the mid ipsilateral tibia, to femur and stabilized by long screws to the ilizarov frame. 3. Application of ilizarov to tibia + bone marrow inserted. Professor Freih Abuhassan - University 11/1/2014 40 of Jordan
  • 41. Professor Freih Abuhassan - University 11/1/2014 41 of Jordan
  • 42. Professor Freih Abuhassan - University 11/1/2014 42 of Jordan
  • 43. Professor Freih Abuhassan - University 11/1/2014 43 of Jordan
  • 44. Professor Freih Abuhassan - 11/1/2014 44 University of Jordan
  • 45. 23rd Dec. 2008 Professor Freih Abuhassan - 11/1/2014 University of Jordan 45
  • 46. Professor Freih Abuhassan - University 11/1/2014 46 of Jordan
  • 47. Professor Freih Abuhassan - University 11/1/2014 47 of Jordan
  • 48. 5th Jan. 2009 Admitted as a case popliteal fossa swelling to R/O organised hematoma U/S: no definite fluid collection but significant soft tissue edema. = Percutaneous evacuation of hematoma, =R/O Orthofix and application of long Ilizarov plate externally and fixed to the graft by Schanz screws Professor Freih Abuhassan - University 11/1/2014 48 of Jordan
  • 49. Followed regularly in OPD Partial weight bearing was started in the on 21st Jan. 2009. Now FWB on crutches Professor Freih Abuhassan - University 11/1/2014 49 of Jordan
  • 50. 25th March 2009 Professor Freih Abuhassan - 11/1/2014 50 University of Jordan
  • 51. Professor Freih Abuhassan - 11/1/2014 51 University of Jordan
  • 52. With Ilizarov family Professor Freih Abuhassan - 11/1/2014 52 University of Jordan
  • 53. ABC In 1942, Jaffe and Lichtenstein first described ABC when they discovered "a peculiar blood containing cyst of large size. Professor Freih Abuhassan - University 11/1/2014 53 of Jordan
  • 54. Benign Aggressive Bone TuLmoocar lly destructive yet do not metastasize or show malignant changes at a cellular levelcellular level ABC, GCT, CMF, Chondroblastoma, Osteoblastoma. Professor Freih Abuhassan - University 11/1/2014 54 of Jordan
  • 55. ABCs represent 1%–2% of all primary bone lesions WHO Blood-filled spaces of variable size,separated by CT containing trabeculae of bone or osteoid tissue and osteoclast giant cells Professor Freih Abuhassan - University 11/1/2014 55 of Jordan
  • 56. D.Dx Giant Cell tumour Aneurysmal bone cyst Telangiectatic osteosarcoma Secondary ABC –upto 35% of all ABCs Most commonly due to GCT (39%) Professor Freih Abuhassan - University 11/1/2014 56 of Jordan
  • 57. No bone is immune 11/1/2014 57
  • 58. Giant Humerus ABC 11/1/2014 Professor Freih Abuhassan - 58 University of Jordan
  • 59. Giant femur ABC Professor Freih Abuhassan - University 11/1/2014 59 of Jordan
  • 60. Giant ABCs Professor Freih Abuhassan - 11/1/2014 60 University of Jordan
  • 61. Treatment depends on site & size of the lesion. Local recurrence rate after classic surgical procedures (curettage and grafting) is about 11.8%–30.8% Professor Freih Abuhassan - University 11/1/2014 61 of Jordan
  • 62. Professor Freih Abuhassan - University 11/1/2014 62 of Jordan