This editorial provides an overview and introduction to a special issue of the International Journal of Critical Infrastructures on enhancing resilience in critical infrastructure systems. It summarizes key concepts discussed in the issue such as infrastructure dependency, interdependency, resilience, and risk governance for interconnected infrastructure systems. The editorial also previews the 10 papers in the special issue, which contribute to understanding how resilience can be applied to address challenges in different critical infrastructure systems and engineering systems more broadly. The papers evaluate approaches for assessing, enhancing, and modeling resilience in areas like transportation, dams, nuclear power plants, and buildings to help infrastructure systems withstand, recover from, and adapt to disruptions.