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MARCH 2017
AMGEN CANADA
TRANSFORMING OUR 
HEALTH SYSTEM TOGETHER
2 Amgen Proprietary—Internal Use Only
WHAT ARE TODAY’S CONCERNS?
↓ ECONOMIC
GROWTH
↑ AGEING
POPULATIONS
↑ FOCUS ON DRUGS
AND PRICING
Express Scripts Says Costly
New Cholesterol Drugs
Could “Wreak Havoc”
Societies face a costly and growing burden of 
serious disease … this is “the enemy”
4 Amgen Proprietary—Internal Use Only
First, let’s take a look at the current fiscal pressures
As a participant in the Canadian healthcare system, Amgen
understands the fiscal challenges that federal/provincial
and territorial governments face
We also believe that we can help improve the system
5 Amgen Proprietary—Internal Use Only
NATIONAL BREAKDOWN OF HEALTHCARE EXPENDITURE
Where is most 
of the money 
being spent 
in 2015?
Source: CIHI, National Health Expenditure Database, October 2015.
6 Amgen Proprietary—Internal Use Only
Benefits of a focus on outcomes: improved patient outcomes,
reduced variation, reduced medical cost, continuous improvement
THE VALUE‐BASED HEALTHCARE SOLUTION
The goal of value-
based healthcare
(VBHC) is to
improve quality
and outcomes
at the same or
lower cost...
Holistic approach ...relying on quality outcome data as
starting point to improve care cycle
7 Amgen Proprietary—Internal Use Only
ICHOM
The International Consortium for Health Outcome Measurement
STANDARDIZED OUTCOMES WE CAN ALL AGREE ON 
• Standardize, meaningful, relevant, patient centered outcomes
• Aspiration: By 2017, we aim to have published Standard Sets covering more than
50 percent of the global disease burden
• 21 set of standards completed as of today
• In Canada, The Montreal Jewish General and Sick Kids have participated in the
elaboration of sets of standards in addition to a number of academics.
www.ichom.org
8 Amgen Proprietary—Internal Use Only
Parameter Improvement Opportunity
Mindset
Recognize value of key stakeholder input; need to collaborate across siloes
Partnerships
Collaborative partnerships across sectors
Data
Capture, analyze & share outcomes and financial data; standard definitions
of outcomes
Policy Multi-year political commitment to enact value and outcome-based policies
Payment
Value-based payment models – override budget silo and annual
budget constraints
WE NEED TO MAKE FUNDAMENTAL SHIFTS TO MOVE 
TOWARDS VALUE‐BASED HEALTHCARE IN CANADA
9 Amgen Proprietary—Internal Use Only
Amgen’s medications target unmet needs and grievous illnesses and we believe they transform patients’
lives. Measuring the health impact of our products in patients is a challenge we are willing to take on
SOLVING THE CHALLENGE TOGETHER
• Adopt VBHC concepts to
move beyond cost measures
only to patient outcomes and
system value
• Agree on measurable outcomes,
modify the financial incentives
from volume to outcomes and
value, ensure the health
technology assessment (HTA)
process includes stronger VBHC
considerations, pan-Canadian
Pharmaceutical Alliance (pCPA)
evolves to negotiate innovative
Product Listing Agreements
• Reward players that implement
integrated system solutions that
promote value
• Ensure that outcomes
measurement is part of every
aspect of healthcare
interventions
Develop Innovative
Solutions
Deliver Value
and Outcomes
Improve
Efficiency
10 Amgen Proprietary—Internal Use Only
We’ve started on this journey and can do more together to serve patients
AMGEN’S COMMITMENT
Our medications are improving patient outcomes for serious
illnesses and contributing value beyond costs
Our programming is focused on enabling system change
We are keen to help deliver outcomes-driven sustainable
healthcare solutions
• Helping payers manage risk
• Identifying ways to use healthcare dollars efficiently
through process improvement
• Supporting quality measures through appropriate indicators
11 Amgen Proprietary—Internal Use Only
QUESTIONS

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GETTING TO ACCESS: TRANSFORMING OUR HEALTH SYSTEM TOGETHER

  • 2. 2 Amgen Proprietary—Internal Use Only WHAT ARE TODAY’S CONCERNS? ↓ ECONOMIC GROWTH ↑ AGEING POPULATIONS ↑ FOCUS ON DRUGS AND PRICING Express Scripts Says Costly New Cholesterol Drugs Could “Wreak Havoc”
  • 4. 4 Amgen Proprietary—Internal Use Only First, let’s take a look at the current fiscal pressures As a participant in the Canadian healthcare system, Amgen understands the fiscal challenges that federal/provincial and territorial governments face We also believe that we can help improve the system
  • 5. 5 Amgen Proprietary—Internal Use Only NATIONAL BREAKDOWN OF HEALTHCARE EXPENDITURE Where is most  of the money  being spent  in 2015? Source: CIHI, National Health Expenditure Database, October 2015.
  • 6. 6 Amgen Proprietary—Internal Use Only Benefits of a focus on outcomes: improved patient outcomes, reduced variation, reduced medical cost, continuous improvement THE VALUE‐BASED HEALTHCARE SOLUTION The goal of value- based healthcare (VBHC) is to improve quality and outcomes at the same or lower cost... Holistic approach ...relying on quality outcome data as starting point to improve care cycle
  • 7. 7 Amgen Proprietary—Internal Use Only ICHOM The International Consortium for Health Outcome Measurement STANDARDIZED OUTCOMES WE CAN ALL AGREE ON  • Standardize, meaningful, relevant, patient centered outcomes • Aspiration: By 2017, we aim to have published Standard Sets covering more than 50 percent of the global disease burden • 21 set of standards completed as of today • In Canada, The Montreal Jewish General and Sick Kids have participated in the elaboration of sets of standards in addition to a number of academics. www.ichom.org
  • 8. 8 Amgen Proprietary—Internal Use Only Parameter Improvement Opportunity Mindset Recognize value of key stakeholder input; need to collaborate across siloes Partnerships Collaborative partnerships across sectors Data Capture, analyze & share outcomes and financial data; standard definitions of outcomes Policy Multi-year political commitment to enact value and outcome-based policies Payment Value-based payment models – override budget silo and annual budget constraints WE NEED TO MAKE FUNDAMENTAL SHIFTS TO MOVE  TOWARDS VALUE‐BASED HEALTHCARE IN CANADA
  • 9. 9 Amgen Proprietary—Internal Use Only Amgen’s medications target unmet needs and grievous illnesses and we believe they transform patients’ lives. Measuring the health impact of our products in patients is a challenge we are willing to take on SOLVING THE CHALLENGE TOGETHER • Adopt VBHC concepts to move beyond cost measures only to patient outcomes and system value • Agree on measurable outcomes, modify the financial incentives from volume to outcomes and value, ensure the health technology assessment (HTA) process includes stronger VBHC considerations, pan-Canadian Pharmaceutical Alliance (pCPA) evolves to negotiate innovative Product Listing Agreements • Reward players that implement integrated system solutions that promote value • Ensure that outcomes measurement is part of every aspect of healthcare interventions Develop Innovative Solutions Deliver Value and Outcomes Improve Efficiency
  • 10. 10 Amgen Proprietary—Internal Use Only We’ve started on this journey and can do more together to serve patients AMGEN’S COMMITMENT Our medications are improving patient outcomes for serious illnesses and contributing value beyond costs Our programming is focused on enabling system change We are keen to help deliver outcomes-driven sustainable healthcare solutions • Helping payers manage risk • Identifying ways to use healthcare dollars efficiently through process improvement • Supporting quality measures through appropriate indicators
  • 11. 11 Amgen Proprietary—Internal Use Only QUESTIONS