This study examined the relationship between positive and negative psychological constructs on well-being in fibromyalgia patients compared to healthy individuals. It hypothesized that fibromyalgia patients would have a stronger correlation between negative affects (like stress, shame, guilt) and well-being measures like pain and quality of life. 81 healthy and 172 fibromyalgia participants completed questionnaires assessing psychological factors and well-being. Results found no significant differences between patients and controls in the relationship between positive constructs like gratitude and well-being. While negative affects correlated more with mental health and pain for healthy individuals, differences were marginal. The hypothesis was not supported as patients were more similar to controls than expected. Understanding patients' psychological experiences can help clinicians in fibromyalgia treatment.