General approach
•Download as PPTX, PDF•
0 likes•205 views
The document reports on 9 cases of drug overdoses and poisonings seen in young males and one female. Cases include zinc phosphide and warfarin rodenticide poisonings, alprazolam and apnea, locaine and methadone with alcohol, clonazepam and alprazolam with opium use, heroin inhalation with dyspnea, alcohol use with abdominal fullness, olanzapine, lorazepam and citalopram overuse, and cannabis inhalation.
Report
Share
Report
Share
Recommended
AAM- 6b: Metabolism of aromatic acids -2 ( Metabolic functions of Phenylalani...
AAM- 6b: Metabolism of aromatic acids -2 ( Metabolic functions of Phenylalani...Dr. Santhosh Kumar. N
This document discusses the metabolism of the aromatic amino acids tyrosine and phenylalanine. It describes:
1. Melanin is synthesized from tyrosine via the enzyme tyrosinase and is the pigment that gives skin, hair, and eyes their color. Deficiencies in tyrosinase result in albinism.
2. Tyrosine and phenylalanine are also precursors for thyroid hormones, catecholamines, and other important biomolecules. The pathways and functions of thyroid hormones, dopamine, norepinephrine, and epinephrine are outlined.
3. Tests for evaluating disorders of catecholamine metabolism like pheochromocytoma (measurement of urinary vanChocolate toxicity in animals by Dr.Amandeep
chocolate toxicity in pet animals is very common due to extensive use of chocolates and various beverages in daily food. Animals got ill by consuming these due to their indiscriminate habit of eating.....
this presentation includes causes, toxic doses, pathogenesis, clinical signs, differential diagnosis & treatment.......HOPE..... PPT WILL HELP :)
Aam 7 metabolism of sulphur containing a.a's
This document discusses the metabolism of sulfur-containing amino acids like methionine and cysteine.
It first describes the catabolism of methionine and the formation of cysteine. It then discusses the resynthesis of methionine through remethylation reactions using vitamins B12 and folate as cofactors.
The catabolism of cysteine through transamination and oxidative pathways is also covered. Cysteine serves important roles like participating in protein structure through disulfide bonds and acting as a precursor for glutathione, taurine, and iron-sulfur clusters.
The document concludes by briefly mentioning some metabolic disorders that can arise from defects in sulfur amino acid metabolism like cystinuria, cyst
Poison-Food-Chain_OC-MJ2014
This document summarizes new restrictions on the use of second-generation anticoagulants (SGARs) commonly found in rodenticides. The California Department of Pesticide Regulation (DPR) reclassified four SGARs in March to restrict them to only professional exterminators by July 1, in response to collateral wildlife deaths from secondary poisoning. Studies by the California Department of Fish and Wildlife (CDFW) scientists found high exposure rates of SGARs in various predators and scavengers that eat poisoned rodents, often resulting in population declines. The restrictions aim to reduce wildlife poisoning by limiting SGAR use to trained professionals.
Sources & Chemistry of Pesticides
Here:
Sources of all pesticides
Chemistry of all pesticides are described.
By
Dr. Yousuf Ali Sarker
DVM(BAU), MS in Pharmacology
Rat poisoning management
Rodenticides are chemicals used to kill rodent pests that can destroy large amounts of grains. They are commonly used but also pose risks to humans and pets through secondary poisoning. Common rodenticides include inorganic preparations like phosphorus and organic preparations like fluoroacetate compounds. Symptoms depend on the specific rodenticide ingested or inhaled and can include abdominal pain, vomiting, seizures, and bleeding. Treatment involves decontamination, supportive care, and antidotes like vitamin K for anticoagulants.
Aluminium Phosphide Poisoning
Toxicology on aluminium phosphide, the characteristics, fatal dose,fatal period, sign and symptoms, postmortem appearance and medicolegal importance are discussed.
Rodenticide Toxicity In Animals by Dr.Amandeep
here you can find most of the rodenticides from different classes and their toxicities(mechanism) in animals specially, along with their treatment...... hope it will help :)
Recommended
AAM- 6b: Metabolism of aromatic acids -2 ( Metabolic functions of Phenylalani...
AAM- 6b: Metabolism of aromatic acids -2 ( Metabolic functions of Phenylalani...Dr. Santhosh Kumar. N
This document discusses the metabolism of the aromatic amino acids tyrosine and phenylalanine. It describes:
1. Melanin is synthesized from tyrosine via the enzyme tyrosinase and is the pigment that gives skin, hair, and eyes their color. Deficiencies in tyrosinase result in albinism.
2. Tyrosine and phenylalanine are also precursors for thyroid hormones, catecholamines, and other important biomolecules. The pathways and functions of thyroid hormones, dopamine, norepinephrine, and epinephrine are outlined.
3. Tests for evaluating disorders of catecholamine metabolism like pheochromocytoma (measurement of urinary vanChocolate toxicity in animals by Dr.Amandeep
chocolate toxicity in pet animals is very common due to extensive use of chocolates and various beverages in daily food. Animals got ill by consuming these due to their indiscriminate habit of eating.....
this presentation includes causes, toxic doses, pathogenesis, clinical signs, differential diagnosis & treatment.......HOPE..... PPT WILL HELP :)
Aam 7 metabolism of sulphur containing a.a's
This document discusses the metabolism of sulfur-containing amino acids like methionine and cysteine.
It first describes the catabolism of methionine and the formation of cysteine. It then discusses the resynthesis of methionine through remethylation reactions using vitamins B12 and folate as cofactors.
The catabolism of cysteine through transamination and oxidative pathways is also covered. Cysteine serves important roles like participating in protein structure through disulfide bonds and acting as a precursor for glutathione, taurine, and iron-sulfur clusters.
The document concludes by briefly mentioning some metabolic disorders that can arise from defects in sulfur amino acid metabolism like cystinuria, cyst
Poison-Food-Chain_OC-MJ2014
This document summarizes new restrictions on the use of second-generation anticoagulants (SGARs) commonly found in rodenticides. The California Department of Pesticide Regulation (DPR) reclassified four SGARs in March to restrict them to only professional exterminators by July 1, in response to collateral wildlife deaths from secondary poisoning. Studies by the California Department of Fish and Wildlife (CDFW) scientists found high exposure rates of SGARs in various predators and scavengers that eat poisoned rodents, often resulting in population declines. The restrictions aim to reduce wildlife poisoning by limiting SGAR use to trained professionals.
Sources & Chemistry of Pesticides
Here:
Sources of all pesticides
Chemistry of all pesticides are described.
By
Dr. Yousuf Ali Sarker
DVM(BAU), MS in Pharmacology
Rat poisoning management
Rodenticides are chemicals used to kill rodent pests that can destroy large amounts of grains. They are commonly used but also pose risks to humans and pets through secondary poisoning. Common rodenticides include inorganic preparations like phosphorus and organic preparations like fluoroacetate compounds. Symptoms depend on the specific rodenticide ingested or inhaled and can include abdominal pain, vomiting, seizures, and bleeding. Treatment involves decontamination, supportive care, and antidotes like vitamin K for anticoagulants.
Aluminium Phosphide Poisoning
Toxicology on aluminium phosphide, the characteristics, fatal dose,fatal period, sign and symptoms, postmortem appearance and medicolegal importance are discussed.
Rodenticide Toxicity In Animals by Dr.Amandeep
here you can find most of the rodenticides from different classes and their toxicities(mechanism) in animals specially, along with their treatment...... hope it will help :)
Wheat pill poisoning presentation
1) The document discusses wheat pill (aluminum phosphide) poisoning, which produces phosphine gas that is toxic and can be fatal in small doses.
2) Phosphine gas causes multiple organ damage by inhibiting cytochrome oxidase and damaging cell membranes. It can cause cardiac arrest, pulmonary edema, liver failure and death.
3) Management of wheat pill poisoning involves gastric lavage with potassium permanganate or oils, magnesium and calcium supplementation, IV fluids, ventilation, inotropes, antiarrhythmics and supportive care over 48-72 hours given the high mortality risk despite treatment.
Razvi n [autosaved]
Treatment of tuberculosis aims to interrupt transmission and cure patients while preventing drug resistance. First-line drugs include isoniazid, rifampin, pyrazinamide, and ethambutol. Standard treatment involves 6 months of these drugs in two phases. Second-line drugs are used when resistance develops. Treatment is monitored for efficacy and toxicity. Directly observed therapy and prevention measures like the BCG vaccine and contact tracing help control tuberculosis.
Insulin
This ppt highlights the discussion pertaining to the drugs acting on endocrine system. This include the discussions on insulin, oral hypoglycemic agents and glucagon. This is based according to Vth semester syllabus.
POISONS AND ANTIDOTES.pptx
The document provides an overview of poisons and antidotes. It discusses the epidemiology of poisoning, classifications of poisons as acute or chronic, and mechanisms and management of common poisons including organophosphates, paracetamol, opioids, hydrocarbons, and alcohol. Key points covered include signs and symptoms of poisoning, use of antidotes like atropine and pralidoxime for organophosphates and N-acetylcysteine for paracetamol overdose.
Op poisning
This document provides information on organophosphate poisoning (OP poisoning) including:
1. OP poisoning is caused by potent nerve agents that inhibit the enzyme acetylcholinesterase. WHO reports millions of cases worldwide annually from accidental and intentional exposure.
2. Clinical manifestations range from mild symptoms like blurred vision and excess saliva to severe symptoms like convulsions, respiratory failure, and death. Treatment involves atropine administration to counteract acetylcholine accumulation along with other supportive care measures.
3. Complications can include intermediate syndrome causing respiratory muscle weakness and organophosphate-induced delayed polyneuropathy requiring long-term recovery support. Proper diagnosis, treatment, and psychiatric evaluation are important for
Common drug and plant poisoning
This document provides an overview of common drug and plant poisonings. It discusses acetaminophen, iron, and anticonvulsant poisonings in detail, outlining their pathophysiology, clinical features, investigations, and management including use of antidotes like N-acetylcysteine and desferoxamine. It also briefly mentions other common drug poisonings and plant toxins like oleander, datura, and jatropha. The goal is to educate about identifying and treating accidental or intentional overdoses of commonly ingested substances.
Clinical Symptoms and Management of Morphine ,Organophosphorus and Mercury ...
The document provides information on morphine, organophosphorus, and mercury poisoning. It discusses the symptoms, diagnosis, and treatment of each type of poisoning. For morphine poisoning, it outlines the three stages of symptoms from excitement to coma. Treatment involves gastric lavage and administration of the antidote naloxone. For organophosphorus poisoning, it describes how the chemicals inhibit acetylcholinesterase leading to excess acetylcholine and lists atropine and oxime compounds as antidotes. Mercury poisoning can be elemental, inorganic, or organic with each having different toxic profiles. Diagnosis involves blood and urine mercury levels while chelation therapy with DMPS is the treatment of choice.
Parkinson’S Disease
1) Parkinson's disease is a progressive degenerative disease of dopaminergic neurons in the substantia nigra, resulting in bradykinesia, tremors, and muscle rigidity.
2) Symptoms develop gradually over months and years and include tremors, slowed movement, rigidity, impaired gait, and eventually dementia.
3) Treatment aims to restore dopaminergic/cholinergic balance and includes levodopa and dopamine agonists which improve quality of life but are not curative. Long term problems include fluctuations in mobility and dyskinesia.
Oct 5 stimulants
The document discusses various stimulant drugs, their effects, and addiction. It covers cocaine, amphetamines, caffeine, nicotine, and more. Two key points are:
1) Stimulant drugs like cocaine and amphetamines disrupt neurotransmitters like dopamine and serotonin in the brain, flooding the system with feelings of pleasure and energy but also making the drugs highly addictive.
2) Long-term stimulant use can have severe medical and psychological consequences like heart attacks, psychosis, and depression due to the unnatural surges in neurotransmitters and subsequent crashes when the drugs wear off. Tolerance and dependence develop rapidly due to positive reinforcement of the drugs' effects.
Catabolism of Purine Nucleotides | Hyperuricemia | Gout
This PPT contains topic on Catabolism of purine nucleotides, Hyperuricemia and Gout.
Book referred: https://www.amazon.in/BIOCHEMISTRY-SATYANARAYANA-5TH-2017/dp/B073Y7XGH4
Anti diabetic drugs
This document discusses different classes of antidiabetic drugs used to treat diabetes mellitus. It describes how these drugs work to lower blood glucose levels by different mechanisms such as increasing insulin secretion from the pancreas, increasing insulin sensitivity, or decreasing glucose absorption. The main classes covered are sulfonylureas, meglitinides, biguanides, thiazolidinediones, alpha-glucosidase inhibitors, and SGLT-2 inhibitors. Specific drugs discussed in more detail include tolbutamide, metformin, and glipizide.
Ppt b blockers presentation
A 59-year-old man was treated for a metoprolol overdose in the emergency department. He became bradycardic and hypotensive despite treatment. Hyperinsulinemia/euglycemia therapy and intravenous lipid emulsion were initiated, and the patient regained spontaneous circulation. The document then discusses various toxic causes of bradycardia and hypotension, treatment approaches including different phases of resuscitation, stabilization and salvage therapies, and specific considerations for beta-blocker overdose management and disposition.
Chronic Kidney Disease
A 54-year-old male was admitted to the hospital with complaints of edema, abdominal pain, decreased urine output, and absence of urine. He had a history of diabetes and hypertension. Laboratory tests found increased creatinine, decreased eGFR, and abnormalities in other values indicating chronic kidney disease. He was diagnosed with chronic kidney disease and prescribed various medications to manage his condition, including amlodipine, atorvastatin, prazosin, pantoprazole, clonidine, torsemide, and calcium carbonate with vitamin D3. The patient received counseling on diet, lifestyle modifications, and monitoring of his condition and medications.
Vasopressors in icu
Vasopressors are drugs that induce vasoconstriction and elevate blood pressure. This document discusses the history, physiology, classification, and pharmacology of various vasopressors used in the ICU setting. It describes how vasopressors act on different adrenergic receptors to increase blood pressure by either increasing cardiac output, systemic vascular resistance, or both. The document reviews commonly used vasopressors like norepinephrine, epinephrine, dopamine, phenylephrine, dobutamine, and ephedrine - outlining their indications, mechanisms of action, pharmacokinetics, and adverse effects.
Acute renal failure
The document provides an overview of acute renal failure (ARF), including its anatomy, physiology, definitions, epidemiology, causes, pathogenesis, clinical features, investigations, complications, management, prognosis and prevention. It discusses ARF in various contexts such as pre-renal, renal and post-renal causes. Key points covered include classification of ARF, common causes like sepsis and nephrotoxins, treatment approaches involving fluid management and dialysis indications. Newborn-specific ARF is also briefly addressed.
Op poisoing.pdf
Organophosphate poisoning is caused by exposure to pesticides, herbicides, and nerve gases. It results in the inhibition of acetylcholinesterase, leading to accumulation of acetylcholine and overstimulation of muscarinic and nicotinic receptors. Symptoms range from mild like nausea to severe like respiratory failure. Treatment involves atropine to block acetylcholine receptors, oximes like pralidoxime to reactivate inhibited acetylcholinesterase, diazepam for seizures, supportive care, and monitoring for complications like pneumonia. Prognosis depends on prompt treatment and severity of exposure.
imipramine, therapeutic drug monitoring
1) Imipramine is a tricyclic antidepressant used to treat psychiatric disorders like depression. Its effectiveness depends on achieving therapeutic plasma concentration ranges through dosage adjustments based on factors like age, liver and kidney function, and other medications.
2) Imipramine's absorption, distribution, metabolism and excretion can be impacted by these patient factors, as well as properties like its high lipophilicity and protein binding. Therapeutic drug monitoring aims to individualize dosing to achieve optimal response while avoiding toxicity.
3) Special populations like pediatrics, geriatrics, and those with hepatic or renal impairment require careful dosage adjustments due to changes in imipramine's
DOC-20230417-WA0000..pdf
This document discusses several inborn metabolic disorders including neonatal hypoglycemia, phenylketonuria, von Gierke disease, and maple syrup urine disease. It defines each condition, describes their typical clinical features and laboratory findings, and outlines treatment approaches. Key points covered include causes of neonatal hypoglycemia like low birth weight; management involving early breastfeeding or IV glucose therapy; features of phenylketonuria like intellectual disability if untreated; and characteristic odors found in maple syrup urine disease and von Gierke disease.
Allopurinol
Allopurinol is a xanthine oxidase inhibitor used to treat gout and hyperuricemia. It works by decreasing uric acid production. Common side effects include skin rashes, though it can also cause life-threatening allergic reactions like Stevens-Johnson syndrome. Due to these risks, allopurinol should be discontinued at the first sign of rash or allergy. It is also important to monitor patients for liver and kidney toxicity.
Antidepressants
A power point presentation on drugs used in depressive disorders for the undergraduate MBBS students of Pharmacology
Can coffee help me lose weight? Yes, 25,422 users in the USA use it for that ...
The South Beach Coffee Java Diet is a variation of the popular South Beach Diet, which was developed by cardiologist Dr. Arthur Agatston. The original South Beach Diet focuses on consuming lean proteins, healthy fats, and low-glycemic index carbohydrates. The South Beach Coffee Java Diet adds the element of coffee, specifically caffeine, to enhance weight loss and improve energy levels.
Top Rated Massage Center In Ajman Chandrima Spa
The best massage spa Ajman is Chandrima Spa Ajman, which was founded in 2023 and is exclusively for men 24 hours a day. As of right now, our parent firm has been providing massage services to over 50,000+ clients in Ajman for the past 10 years. It has about 8+ branches. This demonstrates that Chandrima Spa Ajman is among the most reasonably priced spas in Ajman and the ideal place to unwind and rejuvenate. We provide a wide range of Spa massage treatments, including Indian, Pakistani, Kerala, Malayali, and body-to-body massages. Numerous massage techniques are available, including deep tissue, Swedish, Thai, Russian, and hot stone massages. Our massage therapists produce genuinely unique treatments that generate a revitalized sense of inner serenely by fusing modern techniques, the cleanest natural substances, and traditional holistic therapists.
More Related Content
Similar to General approach
Wheat pill poisoning presentation
1) The document discusses wheat pill (aluminum phosphide) poisoning, which produces phosphine gas that is toxic and can be fatal in small doses.
2) Phosphine gas causes multiple organ damage by inhibiting cytochrome oxidase and damaging cell membranes. It can cause cardiac arrest, pulmonary edema, liver failure and death.
3) Management of wheat pill poisoning involves gastric lavage with potassium permanganate or oils, magnesium and calcium supplementation, IV fluids, ventilation, inotropes, antiarrhythmics and supportive care over 48-72 hours given the high mortality risk despite treatment.
Razvi n [autosaved]
Treatment of tuberculosis aims to interrupt transmission and cure patients while preventing drug resistance. First-line drugs include isoniazid, rifampin, pyrazinamide, and ethambutol. Standard treatment involves 6 months of these drugs in two phases. Second-line drugs are used when resistance develops. Treatment is monitored for efficacy and toxicity. Directly observed therapy and prevention measures like the BCG vaccine and contact tracing help control tuberculosis.
Insulin
This ppt highlights the discussion pertaining to the drugs acting on endocrine system. This include the discussions on insulin, oral hypoglycemic agents and glucagon. This is based according to Vth semester syllabus.
POISONS AND ANTIDOTES.pptx
The document provides an overview of poisons and antidotes. It discusses the epidemiology of poisoning, classifications of poisons as acute or chronic, and mechanisms and management of common poisons including organophosphates, paracetamol, opioids, hydrocarbons, and alcohol. Key points covered include signs and symptoms of poisoning, use of antidotes like atropine and pralidoxime for organophosphates and N-acetylcysteine for paracetamol overdose.
Op poisning
This document provides information on organophosphate poisoning (OP poisoning) including:
1. OP poisoning is caused by potent nerve agents that inhibit the enzyme acetylcholinesterase. WHO reports millions of cases worldwide annually from accidental and intentional exposure.
2. Clinical manifestations range from mild symptoms like blurred vision and excess saliva to severe symptoms like convulsions, respiratory failure, and death. Treatment involves atropine administration to counteract acetylcholine accumulation along with other supportive care measures.
3. Complications can include intermediate syndrome causing respiratory muscle weakness and organophosphate-induced delayed polyneuropathy requiring long-term recovery support. Proper diagnosis, treatment, and psychiatric evaluation are important for
Common drug and plant poisoning
This document provides an overview of common drug and plant poisonings. It discusses acetaminophen, iron, and anticonvulsant poisonings in detail, outlining their pathophysiology, clinical features, investigations, and management including use of antidotes like N-acetylcysteine and desferoxamine. It also briefly mentions other common drug poisonings and plant toxins like oleander, datura, and jatropha. The goal is to educate about identifying and treating accidental or intentional overdoses of commonly ingested substances.
Clinical Symptoms and Management of Morphine ,Organophosphorus and Mercury ...
The document provides information on morphine, organophosphorus, and mercury poisoning. It discusses the symptoms, diagnosis, and treatment of each type of poisoning. For morphine poisoning, it outlines the three stages of symptoms from excitement to coma. Treatment involves gastric lavage and administration of the antidote naloxone. For organophosphorus poisoning, it describes how the chemicals inhibit acetylcholinesterase leading to excess acetylcholine and lists atropine and oxime compounds as antidotes. Mercury poisoning can be elemental, inorganic, or organic with each having different toxic profiles. Diagnosis involves blood and urine mercury levels while chelation therapy with DMPS is the treatment of choice.
Parkinson’S Disease
1) Parkinson's disease is a progressive degenerative disease of dopaminergic neurons in the substantia nigra, resulting in bradykinesia, tremors, and muscle rigidity.
2) Symptoms develop gradually over months and years and include tremors, slowed movement, rigidity, impaired gait, and eventually dementia.
3) Treatment aims to restore dopaminergic/cholinergic balance and includes levodopa and dopamine agonists which improve quality of life but are not curative. Long term problems include fluctuations in mobility and dyskinesia.
Oct 5 stimulants
The document discusses various stimulant drugs, their effects, and addiction. It covers cocaine, amphetamines, caffeine, nicotine, and more. Two key points are:
1) Stimulant drugs like cocaine and amphetamines disrupt neurotransmitters like dopamine and serotonin in the brain, flooding the system with feelings of pleasure and energy but also making the drugs highly addictive.
2) Long-term stimulant use can have severe medical and psychological consequences like heart attacks, psychosis, and depression due to the unnatural surges in neurotransmitters and subsequent crashes when the drugs wear off. Tolerance and dependence develop rapidly due to positive reinforcement of the drugs' effects.
Catabolism of Purine Nucleotides | Hyperuricemia | Gout
This PPT contains topic on Catabolism of purine nucleotides, Hyperuricemia and Gout.
Book referred: https://www.amazon.in/BIOCHEMISTRY-SATYANARAYANA-5TH-2017/dp/B073Y7XGH4
Anti diabetic drugs
This document discusses different classes of antidiabetic drugs used to treat diabetes mellitus. It describes how these drugs work to lower blood glucose levels by different mechanisms such as increasing insulin secretion from the pancreas, increasing insulin sensitivity, or decreasing glucose absorption. The main classes covered are sulfonylureas, meglitinides, biguanides, thiazolidinediones, alpha-glucosidase inhibitors, and SGLT-2 inhibitors. Specific drugs discussed in more detail include tolbutamide, metformin, and glipizide.
Ppt b blockers presentation
A 59-year-old man was treated for a metoprolol overdose in the emergency department. He became bradycardic and hypotensive despite treatment. Hyperinsulinemia/euglycemia therapy and intravenous lipid emulsion were initiated, and the patient regained spontaneous circulation. The document then discusses various toxic causes of bradycardia and hypotension, treatment approaches including different phases of resuscitation, stabilization and salvage therapies, and specific considerations for beta-blocker overdose management and disposition.
Chronic Kidney Disease
A 54-year-old male was admitted to the hospital with complaints of edema, abdominal pain, decreased urine output, and absence of urine. He had a history of diabetes and hypertension. Laboratory tests found increased creatinine, decreased eGFR, and abnormalities in other values indicating chronic kidney disease. He was diagnosed with chronic kidney disease and prescribed various medications to manage his condition, including amlodipine, atorvastatin, prazosin, pantoprazole, clonidine, torsemide, and calcium carbonate with vitamin D3. The patient received counseling on diet, lifestyle modifications, and monitoring of his condition and medications.
Vasopressors in icu
Vasopressors are drugs that induce vasoconstriction and elevate blood pressure. This document discusses the history, physiology, classification, and pharmacology of various vasopressors used in the ICU setting. It describes how vasopressors act on different adrenergic receptors to increase blood pressure by either increasing cardiac output, systemic vascular resistance, or both. The document reviews commonly used vasopressors like norepinephrine, epinephrine, dopamine, phenylephrine, dobutamine, and ephedrine - outlining their indications, mechanisms of action, pharmacokinetics, and adverse effects.
Acute renal failure
The document provides an overview of acute renal failure (ARF), including its anatomy, physiology, definitions, epidemiology, causes, pathogenesis, clinical features, investigations, complications, management, prognosis and prevention. It discusses ARF in various contexts such as pre-renal, renal and post-renal causes. Key points covered include classification of ARF, common causes like sepsis and nephrotoxins, treatment approaches involving fluid management and dialysis indications. Newborn-specific ARF is also briefly addressed.
Op poisoing.pdf
Organophosphate poisoning is caused by exposure to pesticides, herbicides, and nerve gases. It results in the inhibition of acetylcholinesterase, leading to accumulation of acetylcholine and overstimulation of muscarinic and nicotinic receptors. Symptoms range from mild like nausea to severe like respiratory failure. Treatment involves atropine to block acetylcholine receptors, oximes like pralidoxime to reactivate inhibited acetylcholinesterase, diazepam for seizures, supportive care, and monitoring for complications like pneumonia. Prognosis depends on prompt treatment and severity of exposure.
imipramine, therapeutic drug monitoring
1) Imipramine is a tricyclic antidepressant used to treat psychiatric disorders like depression. Its effectiveness depends on achieving therapeutic plasma concentration ranges through dosage adjustments based on factors like age, liver and kidney function, and other medications.
2) Imipramine's absorption, distribution, metabolism and excretion can be impacted by these patient factors, as well as properties like its high lipophilicity and protein binding. Therapeutic drug monitoring aims to individualize dosing to achieve optimal response while avoiding toxicity.
3) Special populations like pediatrics, geriatrics, and those with hepatic or renal impairment require careful dosage adjustments due to changes in imipramine's
DOC-20230417-WA0000..pdf
This document discusses several inborn metabolic disorders including neonatal hypoglycemia, phenylketonuria, von Gierke disease, and maple syrup urine disease. It defines each condition, describes their typical clinical features and laboratory findings, and outlines treatment approaches. Key points covered include causes of neonatal hypoglycemia like low birth weight; management involving early breastfeeding or IV glucose therapy; features of phenylketonuria like intellectual disability if untreated; and characteristic odors found in maple syrup urine disease and von Gierke disease.
Allopurinol
Allopurinol is a xanthine oxidase inhibitor used to treat gout and hyperuricemia. It works by decreasing uric acid production. Common side effects include skin rashes, though it can also cause life-threatening allergic reactions like Stevens-Johnson syndrome. Due to these risks, allopurinol should be discontinued at the first sign of rash or allergy. It is also important to monitor patients for liver and kidney toxicity.
Antidepressants
A power point presentation on drugs used in depressive disorders for the undergraduate MBBS students of Pharmacology
Similar to General approach (20)
Clinical Symptoms and Management of Morphine ,Organophosphorus and Mercury ...
Clinical Symptoms and Management of Morphine ,Organophosphorus and Mercury ...
Catabolism of Purine Nucleotides | Hyperuricemia | Gout
Catabolism of Purine Nucleotides | Hyperuricemia | Gout
Recently uploaded
Can coffee help me lose weight? Yes, 25,422 users in the USA use it for that ...
The South Beach Coffee Java Diet is a variation of the popular South Beach Diet, which was developed by cardiologist Dr. Arthur Agatston. The original South Beach Diet focuses on consuming lean proteins, healthy fats, and low-glycemic index carbohydrates. The South Beach Coffee Java Diet adds the element of coffee, specifically caffeine, to enhance weight loss and improve energy levels.
Top Rated Massage Center In Ajman Chandrima Spa
The best massage spa Ajman is Chandrima Spa Ajman, which was founded in 2023 and is exclusively for men 24 hours a day. As of right now, our parent firm has been providing massage services to over 50,000+ clients in Ajman for the past 10 years. It has about 8+ branches. This demonstrates that Chandrima Spa Ajman is among the most reasonably priced spas in Ajman and the ideal place to unwind and rejuvenate. We provide a wide range of Spa massage treatments, including Indian, Pakistani, Kerala, Malayali, and body-to-body massages. Numerous massage techniques are available, including deep tissue, Swedish, Thai, Russian, and hot stone massages. Our massage therapists produce genuinely unique treatments that generate a revitalized sense of inner serenely by fusing modern techniques, the cleanest natural substances, and traditional holistic therapists.
Rate Controlled Drug Delivery Systems.pdf
Rate Controlled Drug Delivery Systems, Activation Modulated Drug Delivery Systems, Mechanically activated, pH activated, Enzyme activated, Osmotic activated Drug Delivery Systems, Feedback regulated Drug Delivery Systems systems are discussed here.
Innovative Minds France's Most Impactful Healthcare Leaders.pdf
This edition features a handful of Innovative Minds: France's Most Impactful Healthcare Leaders that are leading us into a better future.
Hypotension and role of physiotherapy in it
This particular slides consist of- what is hypotension,what are it's causes and it's effect on body, risk factors, symptoms,complications, diagnosis and role of physiotherapy in it.
This slide is very helpful for physiotherapy students and also for other medical and healthcare students.
Here is the summary of hypotension:
Hypotension, or low blood pressure, is when the pressure of blood circulating in the body is lower than normal or expected. It's only a problem if it negatively impacts the body and causes symptoms. Normal blood pressure is usually between 90/60 mmHg and 120/80 mmHg, but pressures below 90/60 are generally considered hypotensive.
Empowering ACOs: Leveraging Quality Management Tools for MIPS and Beyond
Join us as we delve into the crucial realm of quality reporting for MSSP (Medicare Shared Savings Program) Accountable Care Organizations (ACOs).
In this session, we will explore how a robust quality management solution can empower your organization to meet regulatory requirements and improve processes for MIPS reporting and internal quality programs. Learn how our MeasureAble application enables compliance and fosters continuous improvement.
Gemma Wean- Nutritional solution for Artemia
GEMMA Wean is a high end larval co-feeding and weaning diet aimed at Artemia optimisation and is fortified with a high level of proteins and phospholipids. GEMMA Wean provides the early weaned juveniles with dedicated fish nutrition and is an ideal follow on from GEMMA Micro or Artemia.
GEMMA Wean has an optimised nutritional balance and physical quality so that it flows more freely and spreads readily on the water surface. The balance of phospholipid classes to- gether with the production technology based on a low temperature extrusion process improve the physical aspect of the pellets while still retaining the high phospholipid content.
GEMMA Wean is available in 0.1mm, 0.2mm and 0.3mm. There is also a 0.5mm micro-pellet, GEMMA Wean Diamond, which covers the early nursery stage from post-weaning to pre-growing.
Pediatric Emergency Care for Children | Apollo Hospital
Pediatric Emergency Care for Children | Apollo HospitalApollo 24/7 Adult & Paediatric Emergency Services
At Apollo Hospital, Lucknow, U.P., we provide specialized care for children experiencing dehydration and other symptoms. We also offer NICU & PICU Ambulance Facility Services. Consult our expert today for the best pediatric emergency care.
For More Details:
Map: https://cutt.ly/BwCeflYo
Name: Apollo Hospital
Address: Singar Nagar, LDA Colony, Lucknow, Uttar Pradesh 226012
Phone: 08429021957
Opening Hours: 24X7RECENT ADVANCES IN BREAST CANCER RADIOTHERAPY
ULTRA HYPOFRACTIONATION
Accelerated Partial Breast Irradiation: :Brachytherapy
UK FAST FORWARD
The Power of Superfoods and Exercise.pdf
Healthy Eating Habits:
Understanding Nutrition Labels: Teaches how to read and interpret food labels, focusing on serving sizes, calorie intake, and nutrients to limit or include.
Tips for Healthy Eating: Offers practical advice such as incorporating a variety of foods, practicing moderation, staying hydrated, and eating mindfully.
Benefits of Regular Exercise:
Physical Benefits: Discusses how exercise aids in weight management, muscle and bone health, cardiovascular health, and flexibility.
Mental Benefits: Explains the psychological advantages, including stress reduction, improved mood, and better sleep.
Tips for Staying Active:
Encourages consistency, variety in exercises, setting realistic goals, and finding enjoyable activities to maintain motivation.
Maintaining a Balanced Lifestyle:
Integrating Nutrition and Exercise: Suggests meal planning and incorporating physical activity into daily routines.
Monitoring Progress: Recommends tracking food intake and exercise, regular health check-ups, and provides tips for achieving balance, such as getting sufficient sleep, managing stress, and staying socially active.
Michigan HealthTech Market Map 2024 with Policy Makers, Academic Innovation C...
Michigan HealthTech Market Map 2024. Includes 7 categories: Policy Makers, Academic Innovation Centers, Digital Health Providers, Healthcare Providers, Payers / Insurance, Device Companies, Life Science Companies, Innovation Accelerators. Developed by the Michigan-Israel Business Accelerator
Feeding plate for a newborn with Cleft Palate.pptx
A feeding plate is a prosthetic device used for newborns with a cleft palate to assist in feeding and improve nutrition intake. From a prosthodontic perspective, this plate acts as a barrier between the oral and nasal cavities, facilitating effective sucking and swallowing by providing a more normal anatomical structure. It helps to prevent milk from entering the nasal passage, thereby reducing the risk of aspiration and enhancing the infant's ability to feed efficiently. The feeding plate also aids in the development of the oral muscles and can contribute to better growth and weight gain. Its custom fabrication and proper fitting by a prosthodontist are crucial for ensuring comfort and functionality, as well as for minimizing potential complications. Early intervention with a feeding plate can significantly improve the quality of life for both the infant and the parents.
Top massage center in ajman chandrima Spa
We are one of the top Massage Spa Ajman Our highly skilled, experienced, and certified massage therapists from different corners of the world are committed to serving you with a soothing and relaxing experience. Luxuriate yourself at our spas in Sharjah and Ajman, which are indeed enriched with an ambiance of relaxation and tranquility. We could confidently claim that we are one of the most affordable Spa Ajman and Sharjah as well, where you can book the massage session of your choice for just 99 AED at any time as we are open 24 hours a day, 7 days a week.
Visit : https://massagespaajman.com/
Call : 052 987 1315
MBC Support Group for Black Women – Insights in Genetic Testing.pdf
Christina Spears, breast cancer genetic counselor at the Ohio State University Comprehensive Cancer Center, joined us for the MBC Support Group for Black Women to discuss the importance of genetic testing in communities of color and answer pressing questions.
PrudentRx: A Resource for Patient Education and Engagement
PrudentRx enhances healthcare by educating patients and ensuring effective medication management in a complex, evolving landscape.
TEST BANK For Accounting Information Systems, 3rd Edition by Vernon Richardso...
TEST BANK For Accounting Information Systems, 3rd Edition by Vernon Richardso...rightmanforbloodline
TEST BANK For Accounting Information Systems, 3rd Edition by Vernon Richardson, Verified Chapters 1 - 18, Complete Newest Version
TEST BANK For Accounting Information Systems, 3rd Edition by Vernon Richardson, Verified Chapters 1 - 18, Complete Newest Version
TEST BANK For Accounting Information Systems, 3rd Edition by Vernon Richardson, Verified Chapters 1 - 18, Complete Newest VersionHow Effective is Homeopathic Medicine for Anxiety and Stress Relief.pdf
Have you ever wondered how effective is homeopathic medicine for anxiety and stress relief? Let’s dive into this fascinating topic.
Recently uploaded (20)
Can coffee help me lose weight? Yes, 25,422 users in the USA use it for that ...
Can coffee help me lose weight? Yes, 25,422 users in the USA use it for that ...
Innovative Minds France's Most Impactful Healthcare Leaders.pdf
Innovative Minds France's Most Impactful Healthcare Leaders.pdf
Empowering ACOs: Leveraging Quality Management Tools for MIPS and Beyond
Empowering ACOs: Leveraging Quality Management Tools for MIPS and Beyond
Pediatric Emergency Care for Children | Apollo Hospital
Pediatric Emergency Care for Children | Apollo Hospital
Michigan HealthTech Market Map 2024 with Policy Makers, Academic Innovation C...
Michigan HealthTech Market Map 2024 with Policy Makers, Academic Innovation C...
Feeding plate for a newborn with Cleft Palate.pptx
Feeding plate for a newborn with Cleft Palate.pptx
MBC Support Group for Black Women – Insights in Genetic Testing.pdf
MBC Support Group for Black Women – Insights in Genetic Testing.pdf
PrudentRx: A Resource for Patient Education and Engagement
PrudentRx: A Resource for Patient Education and Engagement
TEST BANK For Accounting Information Systems, 3rd Edition by Vernon Richardso...
TEST BANK For Accounting Information Systems, 3rd Edition by Vernon Richardso...
How Effective is Homeopathic Medicine for Anxiety and Stress Relief.pdf
How Effective is Homeopathic Medicine for Anxiety and Stress Relief.pdf
General approach
- 1. 1. Young – M- RODENTICIDES poisoning – zinc phosphide. 2. Young – M- RODENTICIDES poisoning – Warfarin type- 3. 31 yrs- M – Alprazolam , Apnea – 4. 23 yrs- M – loc , methadone , Alcohol 5. Young- F – clonazepam – Alprazolam – opium 6. 40 yrs- M- dyspnea and whizzing fallowing Heroin inhalation 7. 23 yrs - M – Abdominal fullness , Alcohol use last day 8. Young – M – drug overuse : Olanzapine, lorazepam, citalopram 9. Young – M – Cannabis inhalation -
- 2. general approach • reversal of the underlying disease • the aim is to maintain the arterial pH above 7.1 until the primary process causing the metabolic acidosis can be reversed. • give 1 to 2 meq/kg sodium bicarbonate as an intravenous bolus. We repeat this dose after 30 to 60 minutes if the pH is still less than 7.1.
- 3. Adverse effects ● Increased arterial and tissue capillary PCO2 ● Acceleration of lactate generation ● Reduced ionized calcium ● Hypernatremia ● Extracellular fluid (ECF) volume expansion